{"id":"https://openalex.org/W2607218014","doi":"https://doi.org/10.1007/s11894-017-0558-9","title":"Lactase Non-persistence and Lactose Intolerance","display_name":"Lactase Non-persistence and Lactose Intolerance","publication_year":2017,"publication_date":"2017-04-18","ids":{"openalex":"https://openalex.org/W2607218014","doi":"https://doi.org/10.1007/s11894-017-0558-9","mag":"2607218014","pmid":"https://pubmed.ncbi.nlm.nih.gov/28421381"},"language":"en","primary_location":{"id":"doi:10.1007/s11894-017-0558-9","doi":"https://doi.org/10.1007/s11894-017-0558-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11894-017-0558-9","pdf_url":null,"source":{"id":"https://openalex.org/S62844930","display_name":"Current Gastroenterology Reports","issn_l":"1522-8037","issn":["1522-8037","1534-312X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Gastroenterology Reports","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109103313","display_name":"Theodore M. Bayless","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Theodore M. Bayless","raw_affiliation_strings":[", 800 A Southerly Road, # 1122, Towson, MD, 21286, USA. tbayless@jhmi.edu","Meyerhoff Digestive Diseases-Inflammatory Bowel Disease Center, Gastroenterology Division, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD, 21287, USA. tbayless@jhmi.edu","Meyerhoff Digestive Diseases-Inflammatory Bowel Disease Center, Gastroenterology Division, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD, 21287, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":", 800 A Southerly Road, # 1122, Towson, MD, 21286, USA. tbayless@jhmi.edu","institution_ids":[]},{"raw_affiliation_string":"Meyerhoff Digestive Diseases-Inflammatory Bowel Disease Center, Gastroenterology Division, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD, 21287, USA. tbayless@jhmi.edu","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Meyerhoff Digestive Diseases-Inflammatory Bowel Disease Center, Gastroenterology Division, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD, 21287, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101677648","display_name":"Elizabeth A. Brown","orcid":"https://orcid.org/0000-0002-1137-664X","observed_orcids":["https://orcid.org/0000-0002-1137-664X"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth Brown","raw_affiliation_strings":["Department of Population, Family and Reproductive Health, Johns Hopkins University, Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD, 21205, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Population, Family and Reproductive Health, Johns Hopkins University, Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD, 21205, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109405751","display_name":"David M. Paige","orcid":"https://orcid.org/0000-0002-3788-1994","observed_orcids":["https://orcid.org/0000-0002-3788-1994"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David M. Paige","raw_affiliation_strings":["Department of Population, Family and Reproductive Health, Johns Hopkins University, Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD, 21205, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Population, Family and Reproductive Health, Johns Hopkins University, Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD, 21205, USA","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5109103313"],"corresponding_institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436","https://openalex.org/I4210150714"],"apc_list":{"value":3790,"currency":"USD","value_usd":3790},"apc_paid":null,"fwci":2.7042,"has_fulltext":false,"cited_by_count":234,"citation_normalized_percentile":{"value":0.93018336,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"19","issue":"5","first_page":"23","last_page":"23"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13199","display_name":"Digestive system and related health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13199","display_name":"Digestive system and related health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13984","display_name":"Nutrition, Genetics, and Disease","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lactase-non-persistence","display_name":"lactase non-persistence","score":0.9959999918937683},{"id":"https://openalex.org/keywords/lactose-intolerance","display_name":"lactose intolerance","score":0.9980000257492065},{"id":"https://openalex.org/keywords/lactase-persistence","display_name":"lactase persistence","score":0.8700000047683716},{"id":"https://openalex.org/keywords/milk-consumption","display_name":"milk consumption","score":0.9129999876022339},{"id":"https://openalex.org/keywords/dairy-products","display_name":"dairy products","score":0.6309999823570251},{"id":"https://openalex.org/keywords/calcium-intake","display_name":"calcium intake","score":0.656000018119812},{"id":"https://openalex.org/keywords/vitamin-d-intake","display_name":"vitamin D intake","score":0.8759999871253967},{"id":"https://openalex.org/keywords/irritable-bowel-syndrome","display_name":"irritable bowel syndrome","score":0.6970000267028809},{"id":"https://openalex.org/keywords/northern-european-populations","display_name":"northern European populations","score":0.7260000109672546}],"concepts":[{"id":"https://openalex.org/C2777432071","wikidata":"https://www.wikidata.org/wiki/Q219223","display_name":"Lactose intolerance","level":3,"score":0.9354053735733032},{"id":"https://openalex.org/C2778724459","wikidata":"https://www.wikidata.org/wiki/Q127900","display_name":"Lactose","level":2,"score":0.8724511861801147},{"id":"https://openalex.org/C2778974006","wikidata":"https://www.wikidata.org/wiki/Q379764","display_name":"Lactase","level":3,"score":0.8712807893753052},{"id":"https://openalex.org/C2781009140","wikidata":"https://www.wikidata.org/wiki/Q7170389","display_name":"Persistence (discontinuity)","level":2,"score":0.6352299451828003},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.6230806112289429},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6097774505615234},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.53858482837677},{"id":"https://openalex.org/C2778345441","wikidata":"https://www.wikidata.org/wiki/Q6460735","display_name":"Meal","level":2,"score":0.494502991437912},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.31954115629196167},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2698303759098053},{"id":"https://openalex.org/C187320778","wikidata":"https://www.wikidata.org/wiki/Q1349130","display_name":"Geotechnical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003611","descriptor_name":"Dairy Products","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007787","descriptor_name":"Lactose Intolerance","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D007787","descriptor_name":"Lactose Intolerance","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D007787","descriptor_name":"Lactose Intolerance","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D007787","descriptor_name":"Lactose Intolerance","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008892","descriptor_name":"Milk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015536","descriptor_name":"Down-Regulation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D043183","descriptor_name":"Irritable Bowel Syndrome","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D043183","descriptor_name":"Irritable Bowel Syndrome","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D043322","descriptor_name":"Lactase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D043322","descriptor_name":"Lactase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11894-017-0558-9","doi":"https://doi.org/10.1007/s11894-017-0558-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11894-017-0558-9","pdf_url":null,"source":{"id":"https://openalex.org/S62844930","display_name":"Current Gastroenterology Reports","issn_l":"1522-8037","issn":["1522-8037","1534-312X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Gastroenterology Reports","raw_type":"journal-article"},{"id":"pmid:28421381","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28421381","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current gastroenterology reports","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"},{"score":0.6735000014305115,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":78,"referenced_works":["https://openalex.org/W152651434","https://openalex.org/W326194469","https://openalex.org/W604859579","https://openalex.org/W1528056035","https://openalex.org/W1553764755","https://openalex.org/W1576751645","https://openalex.org/W1709490831","https://openalex.org/W1761524747","https://openalex.org/W1783761218","https://openalex.org/W1946152840","https://openalex.org/W1967788479","https://openalex.org/W1971128853","https://openalex.org/W1976923556","https://openalex.org/W1980367772","https://openalex.org/W1980411008","https://openalex.org/W1984188274","https://openalex.org/W1997010195","https://openalex.org/W2000380175","https://openalex.org/W2001722477","https://openalex.org/W2005743307","https://openalex.org/W2010057578","https://openalex.org/W2020284022","https://openalex.org/W2022720664","https://openalex.org/W2026925931","https://openalex.org/W2036429321","https://openalex.org/W2038640724","https://openalex.org/W2039374563","https://openalex.org/W2044910043","https://openalex.org/W2048024602","https://openalex.org/W2049146458","https://openalex.org/W2059904611","https://openalex.org/W2060459207","https://openalex.org/W2079284289","https://openalex.org/W2080212304","https://openalex.org/W2083485706","https://openalex.org/W2083545762","https://openalex.org/W2084524743","https://openalex.org/W2094575972","https://openalex.org/W2096758237","https://openalex.org/W2098061680","https://openalex.org/W2108090423","https://openalex.org/W2110684190","https://openalex.org/W2118973530","https://openalex.org/W2119224740","https://openalex.org/W2120979046","https://openalex.org/W2121146210","https://openalex.org/W2121665960","https://openalex.org/W2144999720","https://openalex.org/W2147330766","https://openalex.org/W2158993441","https://openalex.org/W2170978984","https://openalex.org/W2174107311","https://openalex.org/W2176113649","https://openalex.org/W2194619413","https://openalex.org/W2208484549","https://openalex.org/W2253798447","https://openalex.org/W2282083000","https://openalex.org/W2298103311","https://openalex.org/W2316468234","https://openalex.org/W2320438215","https://openalex.org/W2323372612","https://openalex.org/W2325446425","https://openalex.org/W2326335154","https://openalex.org/W2334321399","https://openalex.org/W2338650966","https://openalex.org/W2340593010","https://openalex.org/W2345650612","https://openalex.org/W2345691423","https://openalex.org/W2396945236","https://openalex.org/W2406864133","https://openalex.org/W2414775747","https://openalex.org/W2460890813","https://openalex.org/W2562234647","https://openalex.org/W2750038757","https://openalex.org/W4233131722","https://openalex.org/W4247357189","https://openalex.org/W4255982026","https://openalex.org/W4298176356"],"related_works":["https://openalex.org/W2742901038","https://openalex.org/W2123551598","https://openalex.org/W2403027631","https://openalex.org/W1987112022","https://openalex.org/W7221546214","https://openalex.org/W1940010542","https://openalex.org/W2031103971","https://openalex.org/W2406491147","https://openalex.org/W2147330766","https://openalex.org/W2116588486"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":20},{"year":2025,"cited_by_count":25},{"year":2024,"cited_by_count":26},{"year":2023,"cited_by_count":22},{"year":2022,"cited_by_count":31},{"year":2021,"cited_by_count":40},{"year":2020,"cited_by_count":24},{"year":2019,"cited_by_count":23},{"year":2018,"cited_by_count":20},{"year":2017,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2017-04-28T00:00:00"}
