{"id":"https://openalex.org/W2606286146","doi":"https://doi.org/10.2471/blt.16.176677","title":"Transmission of Zika virus through breast milk and other breastfeeding-related bodily-fluids: a systematic review","display_name":"Transmission of Zika virus through breast milk and other breastfeeding-related bodily-fluids: a systematic review","publication_year":2016,"publication_date":"2016-05-02","ids":{"openalex":"https://openalex.org/W2606286146","doi":"https://doi.org/10.2471/blt.16.176677","mag":"2606286146"},"language":"en","primary_location":{"id":"doi:10.2471/blt.16.176677","doi":"https://doi.org/10.2471/blt.16.176677","is_oa":true,"landing_page_url":"https://doi.org/10.2471/blt.16.176677","pdf_url":null,"source":{"id":"https://openalex.org/S22004576","display_name":"Bulletin of the World Health Organization","issn_l":"0042-9686","issn":["0042-9686","1564-0604"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ddh","doaj","dongbi-b","doyens","fnege-4","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319663","host_organization_name":"World Health Organization","host_organization_lineage":["https://openalex.org/P4310319663","https://openalex.org/P4310321776"],"host_organization_lineage_names":["World Health Organization","United Nations"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of the World Health Organization","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.2471/blt.16.176677","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057813658","display_name":"Susannah Colt","orcid":"https://orcid.org/0000-0002-1935-4197","observed_orcids":["https://orcid.org/0000-0002-1935-4197"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susannah Colt","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039538924","display_name":"Maria Nieves Garcia\u2010Casal","orcid":"https://orcid.org/0000-0002-8410-3861","observed_orcids":["https://orcid.org/0000-0002-8410-3861"]},"institutions":[{"id":"https://openalex.org/I4210105654","display_name":"World Health Organization","ror":"https://ror.org/01f80g185","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210105654"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Maria N Garcia-Casal","raw_affiliation_strings":["Evidence and Programme Guidance, Department of Nutrition for Health and Development, World Health Organization, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Evidence and Programme Guidance, Department of Nutrition for Health and Development, World Health Organization, Geneva, Switzerland","institution_ids":["https://openalex.org/I4210105654"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064640046","display_name":"Juan Pablo Pe\u00f1a\u2010Rosas","orcid":"https://orcid.org/0000-0002-6737-9831","observed_orcids":["https://orcid.org/0000-0002-6737-9831"]},"institutions":[{"id":"https://openalex.org/I4210105654","display_name":"World Health Organization","ror":"https://ror.org/01f80g185","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210105654"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Juan Pablo Pe\u00f1a-Rosas","raw_affiliation_strings":["Evidence and Programme Guidance, Department of Nutrition for Health and Development, World Health Organization, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Evidence and Programme Guidance, Department of Nutrition for Health and Development, World Health Organization, Geneva, Switzerland","institution_ids":["https://openalex.org/I4210105654"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059785514","display_name":"Julia Leigh Finkelstein","orcid":"https://orcid.org/0000-0001-9512-5559","observed_orcids":["https://orcid.org/0000-0001-9512-5559"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julia L. Finkelstein","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014537831","display_name":"Pura Rayco\u2010Solon","orcid":"https://orcid.org/0000-0002-6548-1269","observed_orcids":["https://orcid.org/0000-0002-6548-1269"]},"institutions":[{"id":"https://openalex.org/I4210105654","display_name":"World Health Organization","ror":"https://ror.org/01f80g185","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210105654"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Pura Rayco-Solon","raw_affiliation_strings":["Evidence and Programme Guidance, Department of Nutrition for Health and Development, World Health Organization, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Evidence and Programme Guidance, Department of Nutrition for Health and Development, World Health Organization, Geneva, Switzerland","institution_ids":["https://openalex.org/I4210105654"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017368898","display_name":"Zita Weise Prinzo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210105654","display_name":"World Health Organization","ror":"https://ror.org/01f80g185","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210105654"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Zita Weise Prinzo","raw_affiliation_strings":["Evidence and Programme Guidance, Department of Nutrition for Health and Development, World Health Organization, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Evidence and Programme Guidance, Department of Nutrition for Health and Development, World Health Organization, Geneva, Switzerland","institution_ids":["https://openalex.org/I4210105654"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047124475","display_name":"Saurabh Mehta","orcid":"https://orcid.org/0000-0003-3788-0665","observed_orcids":["https://orcid.org/0000-0003-3788-0665"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Saurabh Mehta","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America","institution_ids":["https://openalex.org/I205783295"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.8455,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.91843532,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11581","display_name":"Viral Infections and Outbreaks Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12047","display_name":"Viral Infections and Vectors","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/zika-virus","display_name":"Zika virus","score":0.9950000047683716},{"id":"https://openalex.org/keywords/breastfeeding","display_name":"breastfeeding","score":0.6600000262260437},{"id":"https://openalex.org/keywords/breast-milk","display_name":"breast milk","score":0.8640000224113464},{"id":"https://openalex.org/keywords/vertical-transmission","display_name":"vertical transmission","score":0.9089999794960022},{"id":"https://openalex.org/keywords/perinatal-transmission","display_name":"perinatal transmission","score":0.8209999799728394},{"id":"https://openalex.org/keywords/sweat","display_name":"sweat","score":0.43700000643730164},{"id":"https://openalex.org/keywords/maternal-infection","display_name":"maternal infection","score":0.4090000092983246},{"id":"https://openalex.org/keywords/rt-pcr-detection","display_name":"RT-PCR detection","score":0.625},{"id":"https://openalex.org/keywords/mosquito-borne-diseases","display_name":"mosquito-borne diseases","score":0.7059999704360962}],"concepts":[{"id":"https://openalex.org/C2777053367","wikidata":"https://www.wikidata.org/wiki/Q202864","display_name":"Zika virus","level":3,"score":0.8823800086975098},{"id":"https://openalex.org/C2776283161","wikidata":"https://www.wikidata.org/wiki/Q174876","display_name":"Breastfeeding","level":2,"score":0.7587968111038208},{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.5740764737129211},{"id":"https://openalex.org/C2775871700","wikidata":"https://www.wikidata.org/wiki/Q22728","display_name":"Breast milk","level":2,"score":0.5702207684516907},{"id":"https://openalex.org/C3020294031","wikidata":"https://www.wikidata.org/wiki/Q174876","display_name":"Breast feeding","level":2,"score":0.562586784362793},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5511309504508972},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.47586458921432495},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.3851695954799652},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3261473774909973},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.17159277200698853},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.14351493120193481},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0738520622253418},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2471/blt.16.176677","doi":"https://doi.org/10.2471/blt.16.176677","is_oa":true,"landing_page_url":"https://doi.org/10.2471/blt.16.176677","pdf_url":null,"source":{"id":"https://openalex.org/S22004576","display_name":"Bulletin of the World Health Organization","issn_l":"0042-9686","issn":["0042-9686","1564-0604"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ddh","doaj","dongbi-b","doyens","fnege-4","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319663","host_organization_name":"World Health Organization","host_organization_lineage":["https://openalex.org/P4310319663","https://openalex.org/P4310321776"],"host_organization_lineage_names":["World Health Organization","United Nations"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of the World Health Organization","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.2471/blt.16.176677","doi":"https://doi.org/10.2471/blt.16.176677","is_oa":true,"landing_page_url":"https://doi.org/10.2471/blt.16.176677","pdf_url":null,"source":{"id":"https://openalex.org/S22004576","display_name":"Bulletin of the World Health Organization","issn_l":"0042-9686","issn":["0042-9686","1564-0604"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ddh","doaj","dongbi-b","doyens","fnege-4","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319663","host_organization_name":"World Health Organization","host_organization_lineage":["https://openalex.org/P4310319663","https://openalex.org/P4310321776"],"host_organization_lineage_names":["World Health Organization","United Nations"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of the World Health Organization","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"},{"score":0.40450000762939453,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3122844274","https://openalex.org/W2777333691","https://openalex.org/W2921380275","https://openalex.org/W2587185378","https://openalex.org/W2913897583","https://openalex.org/W2916529057","https://openalex.org/W2482418871","https://openalex.org/W2775153848","https://openalex.org/W3017741623","https://openalex.org/W4224313383"],"abstract_inverted_index":{"Background":[0],"\r\nZika":[1],"virus":[2],"(ZIKV)":[3],"infection":[4,43,66,98],"is":[5,11,217],"an":[6,14],"emerging":[7],"mosquito-borne":[8],"disease,":[9],"which":[10],"associated":[12,112],"with":[13,64,189],"increase":[15],"in":[16,44,67,122,135,159,196],"central":[17],"nervous":[18],"system":[19],"malformations":[20],"and":[21,38,58,73,147,163,186],"newborn":[22],"microcephaly":[23],"cases.":[24],"This":[25],"review":[26,52],"investigated":[27],"evidence":[28,115,216],"of":[29,41,53,96,105,108,116,125,174,184,200],"breastfeeding":[30,62,176,221],"transmission":[31,212,222,226],"from":[32,223],"ZIKV-infected":[33,175,190],"mothers":[34,101,137,161,177],"to":[35,209,219],"their":[36],"children":[37],"the":[39,103,109,197,204],"presence":[40],"ZIKV":[42,65,97,117,119,157,193,211],"breastfeeding-related":[45],"fluids.\r\n\r\n\r\nMethodology/Principal":[46],"findings":[47],"\r\nWe":[48,170],"conducted":[49,76],"a":[50,78],"systematic":[51],"observational":[54],"studies,":[55,57],"case":[56,86],"surveillance":[59],"reports":[60,87],"involving":[61],"women":[63],"several":[68],"international":[69],"databases.":[70],"Data":[71],"extraction":[72],"analysis":[74],"were":[75,133,156,179],"following":[77],"PROSPERO-registered":[79],"protocol.":[80],"From":[81],"472":[82],"non-duplicate":[83],"records,":[84],"two":[85,187],"met":[88],"criteria":[89],"for":[90,151,168],"inclusion.":[91],"We":[92],"reviewed":[93],"three":[94,110,127,172,182,202],"cases":[95,173,188],"among":[99],"lactating":[100],"near":[102],"time":[104],"delivery.":[106],"Two":[107],"(2/3)":[111],"newborns":[113],"had":[114],"infection.":[118],"was":[120,142,149,165,194],"detected":[121,195],"breast":[123,198],"milk":[124,130,199],"all":[126,136,160,201],"mothers.":[128],"Breast":[129],"detection":[131],"results":[132],"positive":[134,143,158],"(3/3)":[138],"by":[139,144],"RT-PCR,":[140],"one":[141],"culture":[145],"(1/3),":[146],"none":[148],"tested":[150,167],"ZIKV-specific":[152],"antibodies.":[153],"Serum":[154],"samples":[155],"(3/3),":[162],"sweat":[164],"not":[166,207],"ZIKV.\r\n\r\n\r\nConclusions/Significance":[169],"describe":[171],"who":[178],"symptomatic":[180],"within":[181],"days":[183],"delivery,":[185],"newborns.":[191],"While":[192],"mothers,":[203],"data":[205],"are":[206],"sufficient":[208],"conclude":[210],"via":[213],"breastfeeding.":[214],"More":[215],"needed":[218],"distinguish":[220],"other":[224],"perinatal":[225],"routes.":[227]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2017-04-28T00:00:00"}