{"id":"https://openalex.org/W2605287328","doi":"https://doi.org/10.1128/iai.00001-17","title":"Key Role of Capsular Polysaccharide in the Induction of Systemic Infection and Abortion by Hypervirulent Campylobacter jejuni","display_name":"Key Role of Capsular Polysaccharide in the Induction of Systemic Infection and Abortion by Hypervirulent Campylobacter jejuni","publication_year":2017,"publication_date":"2017-04-04","ids":{"openalex":"https://openalex.org/W2605287328","doi":"https://doi.org/10.1128/iai.00001-17","mag":"2605287328","pmid":"https://pubmed.ncbi.nlm.nih.gov/28373351","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5442617"},"language":"en","primary_location":{"id":"doi:10.1128/iai.00001-17","doi":"https://doi.org/10.1128/iai.00001-17","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.00001-17","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5442617","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025498781","display_name":"Orhan \u015eahin","orcid":"https://orcid.org/0000-0003-0262-4581","observed_orcids":["https://orcid.org/0000-0003-0262-4581"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Orhan Sahin","raw_affiliation_strings":["Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, Iowa, USA","Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]},{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043201022","display_name":"Samantha Terhorst","orcid":"https://orcid.org/0009-0005-5727-4218","observed_orcids":["https://orcid.org/0009-0005-5727-4218"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samantha A. Terhorst","raw_affiliation_strings":["Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069830570","display_name":"Eric Ryan Burrough","orcid":"https://orcid.org/0000-0003-4747-9189","observed_orcids":["https://orcid.org/0000-0003-4747-9189"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric R. Burrough","raw_affiliation_strings":["Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088962691","display_name":"Zhangqi Shen","orcid":"https://orcid.org/0000-0003-4789-7540","observed_orcids":["https://orcid.org/0000-0003-4789-7540"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhangqi Shen","raw_affiliation_strings":["Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078767515","display_name":"Zuowei Wu","orcid":"https://orcid.org/0000-0003-2153-5816","observed_orcids":["https://orcid.org/0000-0003-2153-5816"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zuowei Wu","raw_affiliation_strings":["Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101736240","display_name":"Lei Dai","orcid":"https://orcid.org/0000-0002-7688-9817","observed_orcids":["https://orcid.org/0000-0002-7688-9817"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lei Dai","raw_affiliation_strings":["Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031831726","display_name":"Yizhi Tang","orcid":"https://orcid.org/0000-0003-0805-7020","observed_orcids":["https://orcid.org/0000-0003-0805-7020"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yizhi Tang","raw_affiliation_strings":["Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027984887","display_name":"Paul Joseph Plummer","orcid":"https://orcid.org/0000-0002-5784-8382","observed_orcids":["https://orcid.org/0000-0002-5784-8382"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul J. Plummer","raw_affiliation_strings":["Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, Iowa, USA","Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]},{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057914265","display_name":"Ju Ji","orcid":"https://orcid.org/0000-0001-7281-1636","observed_orcids":["https://orcid.org/0000-0001-7281-1636"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ju Ji","raw_affiliation_strings":["Department of Statistics, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103043986","display_name":"Michael J. Yaeger","orcid":"https://orcid.org/0000-0002-7259-8414","observed_orcids":["https://orcid.org/0000-0002-7259-8414"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael J. Yaeger","raw_affiliation_strings":["Department of Veterinary Pathology, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Pathology, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086172106","display_name":"Qijing Zhang","orcid":"https://orcid.org/0009-0005-8690-1655","observed_orcids":["https://orcid.org/0009-0005-8690-1655"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qijing Zhang","raw_affiliation_strings":["Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I173911158"],"apc_list":null,"apc_paid":null,"fwci":2.6209,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.87819364,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"85","issue":"6","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/campylobacter-jejuni","display_name":"Campylobacter jejuni","score":0.9950000047683716},{"id":"https://openalex.org/keywords/capsular-polysaccharide","display_name":"capsular polysaccharide","score":0.9980000257492065},{"id":"https://openalex.org/keywords/ovine-abortion","display_name":"ovine abortion","score":0.9369999766349792},{"id":"https://openalex.org/keywords/bacteremia","display_name":"bacteremia","score":0.9449999928474426},{"id":"https://openalex.org/keywords/systemic-infection","display_name":"systemic infection","score":0.9449999928474426},{"id":"https://openalex.org/keywords/virulence-factors","display_name":"virulence factors","score":0.5820000171661377},{"id":"https://openalex.org/keywords/zoonotic-pathogens","display_name":"zoonotic pathogens","score":0.5440000295639038},{"id":"https://openalex.org/keywords/vaccine-development","display_name":"vaccine development","score":0.5540000200271606}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8275644183158875},{"id":"https://openalex.org/C2776957140","wikidata":"https://www.wikidata.org/wiki/Q265488","display_name":"Campylobacter jejuni","level":3,"score":0.8225122690200806},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7186985015869141},{"id":"https://openalex.org/C2778642596","wikidata":"https://www.wikidata.org/wiki/Q8452","display_name":"Abortion","level":3,"score":0.6005537509918213},{"id":"https://openalex.org/C155292618","wikidata":"https://www.wikidata.org/wiki/Q1137328","display_name":"Bacterial capsule","level":4,"score":0.4265343248844147},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.35683006048202515},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.33348268270492554},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3130542039871216},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.27273428440093994},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.23265424370765686},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000031","descriptor_name":"Abortion, Septic","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002169","descriptor_name":"Campylobacter Infections","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002169","descriptor_name":"Campylobacter Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006168","descriptor_name":"Guinea Pigs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011135","descriptor_name":"Polysaccharides, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011135","descriptor_name":"Polysaccharides, Bacterial","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015964","descriptor_name":"Gene Expression Regulation, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016123","descriptor_name":"Campylobacter jejuni","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016123","descriptor_name":"Campylobacter jejuni","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D016667","descriptor_name":"Bacterial Capsules","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016667","descriptor_name":"Bacterial Capsules","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D037521","descriptor_name":"Virulence Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1128/iai.00001-17","doi":"https://doi.org/10.1128/iai.00001-17","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.00001-17","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4608556","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5442617","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5442617","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5442617","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infect Immun","raw_type":"Text"},{"id":"pmid:28373351","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28373351","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and immunity","raw_type":"Journal Article"},{"id":"pmh:oai:lib.dr.iastate.edu:vdpam_pubs-1091","doi":null,"is_oa":false,"landing_page_url":"https://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=1091&context=vdpam_pubs","pdf_url":null,"source":{"id":"https://openalex.org/S4377196104","display_name":"Iowa State University Digital Repository (Iowa State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I173911158","host_organization_name":"Iowa State University","host_organization_lineage":["https://openalex.org/I173911158"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Veterinary Diagnostic and Production Animal Medicine Publications","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4608556","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5442617","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6032145818","display_name":null,"funder_award_id":"2013-67015-20368","funder_id":"https://openalex.org/F4320332299","funder_display_name":"National Institute of Food and Agriculture"}],"funders":[{"id":"https://openalex.org/F4320332299","display_name":"National Institute of Food and Agriculture","ror":"https://ror.org/05qx3fv49"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W1551746096","https://openalex.org/W1828780954","https://openalex.org/W1845975704","https://openalex.org/W1849301422","https://openalex.org/W1937678612","https://openalex.org/W1974388389","https://openalex.org/W1977101213","https://openalex.org/W1979349667","https://openalex.org/W1984536951","https://openalex.org/W1996518446","https://openalex.org/W2003496942","https://openalex.org/W2006316123","https://openalex.org/W2016778738","https://openalex.org/W2025733027","https://openalex.org/W2027358702","https://openalex.org/W2048227696","https://openalex.org/W2048622484","https://openalex.org/W2048895133","https://openalex.org/W2050356851","https://openalex.org/W2052120864","https://openalex.org/W2058305781","https://openalex.org/W2058327542","https://openalex.org/W2059242915","https://openalex.org/W2060308269","https://openalex.org/W2079081483","https://openalex.org/W2079096624","https://openalex.org/W2086162150","https://openalex.org/W2089525460","https://openalex.org/W2100494795","https://openalex.org/W2103540045","https://openalex.org/W2104638396","https://openalex.org/W2108368634","https://openalex.org/W2109757350","https://openalex.org/W2119101052","https://openalex.org/W2119217447","https://openalex.org/W2120904752","https://openalex.org/W2122758896","https://openalex.org/W2123244912","https://openalex.org/W2128154577","https://openalex.org/W2128214209","https://openalex.org/W2129217207","https://openalex.org/W2132815440","https://openalex.org/W2138593217","https://openalex.org/W2142993603","https://openalex.org/W2151558818","https://openalex.org/W2152727327","https://openalex.org/W2159156173","https://openalex.org/W2159162370","https://openalex.org/W2160502540","https://openalex.org/W2163537711","https://openalex.org/W2168302495","https://openalex.org/W2170565907","https://openalex.org/W2185023692","https://openalex.org/W2514778355","https://openalex.org/W4391200357","https://openalex.org/W4409137095"],"related_works":["https://openalex.org/W138798669","https://openalex.org/W2105635920","https://openalex.org/W2058305781","https://openalex.org/W50448626","https://openalex.org/W2109871362","https://openalex.org/W2132815440","https://openalex.org/W2601964469","https://openalex.org/W3094987684","https://openalex.org/W7098177572","https://openalex.org/W2149570030"],"abstract_inverted_index":{"ABSTRACT":[0],"Campylobacter":[1,33],"jejuni":[2,61,118,258],"is":[3,62],"a":[4,8,100,107,123,135,201,206,230,247],"zoonotic":[5],"pathogen,":[6],"and":[7,45,79,103,121,134,162,191,223,240,245],"hypervirulent":[9,256],"clone,":[10],"named":[11],"clone":[12,124,198,216],"SA,":[13],"has":[14,210],"recently":[15],"emerged":[16],"as":[17,229],"the":[18,25,37,43,47,70,93,155,235,251],"predominant":[19],"cause":[20],"of":[21,95,139,145,158,170,237,253],"ovine":[22],"abortion":[23,81,105,163,241],"in":[24,42,53,76,82,97,104,129,141,151,160,164,187,214,242],"United":[26],"States.":[27],"To":[28],"induce":[29],"abortion,":[30],"orally":[31],"ingested":[32],"must":[34],"translocate":[35],"across":[36],"intestinal":[38],"epithelium,":[39],"spread":[40],"systemically":[41],"circulation,":[44],"reach":[46],"fetoplacental":[48],"tissue.":[49],"Bacterial":[50],"factors":[51],"involved":[52],"these":[54,176],"steps":[55],"are":[56],"not":[57],"well":[58],"understood.":[59],"C.":[60,117,257],"known":[63],"to":[64,85,154],"produce":[65],"capsular":[66],"polysaccharide":[67],"(CPS),":[68],"but":[69],"specific":[71],"role":[72,94],"that":[73,197],"CPS":[74,96,203,228],"plays":[75],"systemic":[77,238],"infection":[78,239],"particularly":[80],"animals":[83,244],"remains":[84],"be":[86],"determined.":[87],"In":[88],"this":[89],"study,":[90],"we":[91],"evaluated":[92],"bacteremia":[98,140,159],"using":[99,106],"mouse":[101],"model":[102,111],"pregnant":[108,165,243],"guinea":[109,166,188],"pig":[110,189],"following":[112],"oral":[113],"challenge.":[114],"Compared":[115],"with":[116,205],"NCTC":[119],"11168":[120],"81-176,":[122],"SA":[125,199,217],"isolate":[126],"(IA3902)":[127],"resulted":[128],"significantly":[130,136],"higher":[131],"bacterial":[132],"counts":[133],"longer":[137],"duration":[138],"mice.":[142],"The":[143,178],"loss":[144],"capsule":[146,171,179],"production":[147],"via":[148],"gene-specific":[149],"mutagenesis":[150],"IA3902":[152],"led":[153],"complete":[156],"abolishment":[157],"mice":[161],"pigs,":[167],"while":[168],"complementation":[169],"expression":[172],"almost":[173],"fully":[174],"restored":[175],"phenotypes.":[177],"mutant":[180],"strain":[181],"was":[182],"also":[183],"impaired":[184],"for":[185,234,250],"survival":[186],"sera":[190],"sheep":[192],"blood.":[193],"Sequence-based":[194],"analyses":[195],"revealed":[196],"possesses":[200],"unique":[202],"locus":[204],"mosaic":[207],"structure,":[208],"which":[209],"been":[211],"stably":[212],"maintained":[213],"all":[215],"isolates":[218],"derived":[219],"from":[220],"various":[221],"hosts":[222],"times.":[224],"These":[225],"findings":[226],"establish":[227],"key":[231],"virulence":[232],"factor":[233],"induction":[236],"provide":[246],"viable":[248],"candidate":[249],"development":[252],"vaccines":[254],"against":[255],".":[259]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-04-14T00:00:00"}