{"id":"https://openalex.org/W2604371193","doi":null,"title":"Original Investigation Urine Potassium Excretion, Kidney Failure, and Mortality in CKD","display_name":"Original Investigation Urine Potassium Excretion, Kidney Failure, and Mortality in CKD","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2604371193","mag":"2604371193"},"language":"en","primary_location":{"id":"mag:2604371193","doi":null,"is_oa":false,"landing_page_url":"https://www.ajkd.org/article/S0272-6386(16)30102-0/pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046199401","display_name":"Amanda K. Leonberg\u2010Yoo","orcid":"https://orcid.org/0000-0001-9810-9298","observed_orcids":["https://orcid.org/0000-0001-9810-9298"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amanda K. Leonberg\u2010Yoo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9810-9298","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061553198","display_name":"Hocine Tighiouart","orcid":"https://orcid.org/0000-0003-1448-327X","observed_orcids":["https://orcid.org/0000-0003-1448-327X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hocine Tighiouart","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032690087","display_name":"Andrew S. Levey","orcid":"https://orcid.org/0000-0003-1491-501X","observed_orcids":["https://orcid.org/0000-0003-1491-501X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew S. Levey","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108478740","display_name":"Gerald J. Beck","orcid":"https://orcid.org/0000-0002-8876-5045","observed_orcids":["https://orcid.org/0000-0002-8876-5045"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gerald J. Beck","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5076361487","display_name":"Mark J. Sarnak","orcid":"https://orcid.org/0000-0002-2457-6368","observed_orcids":["https://orcid.org/0000-0002-2457-6368","https://orcid.org/0000-0003-4927-6609"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark J. Sarnak","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4927-6609","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12876","display_name":"Potassium and Related Disorders","score":0.39750000834465027,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12876","display_name":"Potassium and Related Disorders","score":0.39750000834465027,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.3125,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.11089999973773956,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.9079999923706055},{"id":"https://openalex.org/keywords/kidney-failure","display_name":"renal failure","score":0.9710000157356262},{"id":"https://openalex.org/keywords/all-cause-mortality","display_name":"all-cause mortality","score":0.9470000267028809},{"id":"https://openalex.org/keywords/potassium-intake","display_name":"potassium intake","score":0.9649999737739563},{"id":"https://openalex.org/keywords/dialysis-initiation","display_name":"dialysis initiation","score":0.847000002861023},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.9200000166893005},{"id":"https://openalex.org/keywords/mdrd-study","display_name":"MDRD Study","score":0.7910000085830688},{"id":"https://openalex.org/keywords/kidney-disease-progression","display_name":"kidney disease progression","score":0.5389999747276306}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8168483972549438},{"id":"https://openalex.org/C2779978075","wikidata":"https://www.wikidata.org/wiki/Q202301","display_name":"Dialysis","level":2,"score":0.6691480278968811},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.6246811151504517},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.6151431798934937},{"id":"https://openalex.org/C10146269","wikidata":"https://www.wikidata.org/wiki/Q185557","display_name":"Excretion","level":2,"score":0.6130712032318115},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5752126574516296},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.46344637870788574},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.43020346760749817},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.41392984986305237},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2604371193","doi":null,"is_oa":false,"landing_page_url":"https://www.ajkd.org/article/S0272-6386(16)30102-0/pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1974997866","https://openalex.org/W1990590422","https://openalex.org/W1993785612","https://openalex.org/W1998613034","https://openalex.org/W2020620294","https://openalex.org/W2058705761","https://openalex.org/W2062961637","https://openalex.org/W2071619992","https://openalex.org/W2075391935","https://openalex.org/W2079054690","https://openalex.org/W2101610091","https://openalex.org/W2106062322","https://openalex.org/W2106445408","https://openalex.org/W2113489501","https://openalex.org/W2130131216","https://openalex.org/W2131828349","https://openalex.org/W2135383573","https://openalex.org/W2148680864","https://openalex.org/W2154055479","https://openalex.org/W2171699929","https://openalex.org/W2174290084","https://openalex.org/W2177296427","https://openalex.org/W2260087147","https://openalex.org/W2305607443","https://openalex.org/W2321986725","https://openalex.org/W2626133752"],"related_works":["https://openalex.org/W2398596652","https://openalex.org/W3165937972","https://openalex.org/W4220885288","https://openalex.org/W4396990767","https://openalex.org/W2012967253","https://openalex.org/W2773577141","https://openalex.org/W7100585975","https://openalex.org/W2938277838","https://openalex.org/W1683574448","https://openalex.org/W2121869897"],"abstract_inverted_index":{"Background:":[0],"Low":[1],"urine":[2,33,116,131,192,205,236,244,278],"potassium":[3,10,34,117,132,193,206,237,245,252,279],"excretion,":[4,118],"as":[5,128,138,247],"a":[6,23,61,248,258,298],"surrogate":[7,249],"for":[8,17,165,219,227,250,286],"dietary":[9,82,251],"intake,":[11],"is":[12],"associated":[13,209,282],"with":[14,35,96,173,186,210,283],"higher":[15,203],"risk":[16,285],"hypertension":[18],"and":[19,81,122,222,262,266],"cardiovascular":[20],"disease":[21,41,87],"in":[22,38,56,69,89],"general":[24,273],"population.":[25,275],"Few":[26],"studies":[27],"have":[28],"investigated":[29],"the":[30,75,158,272,301],"relationship":[31],"of":[32,54,77,140,214],"clinical":[36],"outcomes":[37],"chronic":[39],"kidney":[40,86,166,220,291],"(CKD).":[42],"Study":[43,59],"Design:":[44],"Longitudinal":[45],"cohort":[46],"study.":[47],"Setting":[48],"&":[49],"Participants:":[50],"The":[51,110],"MDRD":[52],"(Modification":[53],"Diet":[55],"Renal":[57,149],"Disease)":[58],"was":[60,114,145,155,168,181,195,208,281],"randomized":[62],"controlled":[63],"trial":[64],"(N":[65],"5":[66],"840)":[67],"conducted":[68],"1989":[70],"to":[71,73,93,100,271],"1993":[72],"examine":[74],"effects":[76],"blood":[78],"pressure":[79],"control":[80],"protein":[83],"restriction":[84],"on":[85],"progression":[88],"adults":[90],"aged":[91],"18":[92],"70":[94],"years":[95],"CKD":[97,264,274],"stages":[98],"2":[99],"4.":[101],"This":[102],"post":[103],"hoc":[104],"analysis":[105],"included":[106],"812":[107],"participants.":[108],"Predictor:":[109],"primary":[111],"predictor":[112],"variable":[113],"24-hour":[115],"measured":[119],"at":[120,123],"baseline":[121,204],"multiple":[124],"time":[125],"points":[126],"(presented":[127],"time-updated":[129,234],"average":[130,235],"excretion).":[133],"Outcomes:":[134],"Kidney":[135,295,303],"failure,":[136],"defined":[137],"initiation":[139],"dialysis":[141],"therapy":[142],"or":[143],"transplantation,":[144],"determined":[146],"from":[147,257],"US":[148],"Data":[150],"System":[151],"data.":[152],"All-cause":[153],"mortality":[154,179],"assessed":[156],"using":[157,233,243],"National":[159,302],"Death":[160],"Index.":[161],"Results:":[162],"Median":[163,177],"follow-up":[164,180],"failure":[167,221],"6.1":[169],"(IQR,":[170,183],"3.5-11.7)":[171],"years,":[172,185],"9":[174],"events/100":[175],"patient-years.":[176,189],"all-cause":[178,228,287],"19.2":[182],"10.8-20.6)":[184],"3":[187],"deaths/100":[188],"Baseline":[190],"mean":[191],"excretion":[194,246,280],"2.39":[196],"6":[197],"0.89":[198],"(SD)":[199],"g/d.":[200],"Each":[201],"1-SD":[202],"level":[207],"an":[211],"adjusted":[212],"HR":[213],"0.95":[215],"(95%":[216,224],"CI,":[217,225],"0.87-1.04)":[218],"0.83":[223],"0.74-0.94)":[226],"mortality.":[229],"Results":[230,254],"were":[231,241],"consistent":[232],"measurements.":[238],"Limitations:":[239],"Analyses":[240],"performed":[242],"intake.":[253],"are":[255],"obtained":[256],"primarily":[259],"young,":[260],"nondiabetic,":[261],"advanced":[263],"population":[265],"may":[267],"not":[268,290],"be":[269],"generalizable":[270],"Conclusions:":[276],"Higher":[277],"lower":[284],"mortality,":[288],"but":[289],"failure.":[292],"Am":[293],"J":[294],"Dis.":[296],"69(3):341-349.":[297],"2016":[299],"by":[300],"Foundation,":[304],"Inc.":[305]},"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2017-04-14T00:00:00"}