{"id":"https://openalex.org/W2604112126","doi":"https://doi.org/10.1200/jco.2004.22.14_suppl.7207","title":"A phase II study of a 3-day schedule with topotecan and cisplatin every three weeks in patients with previously in treated small cell lung cancer and extensive disease: Final results","display_name":"A phase II study of a 3-day schedule with topotecan and cisplatin every three weeks in patients with previously in treated small cell lung cancer and extensive disease: Final results","publication_year":2004,"publication_date":"2004-07-15","ids":{"openalex":"https://openalex.org/W2604112126","doi":"https://doi.org/10.1200/jco.2004.22.14_suppl.7207","mag":"2604112126"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2004.22.14_suppl.7207","doi":"https://doi.org/10.1200/jco.2004.22.14_suppl.7207","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2004.22.14_suppl.7207","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077199450","display_name":"Ulrik Lassen","orcid":"https://orcid.org/0000-0002-3865-4574","observed_orcids":["https://orcid.org/0000-0002-3865-4574"]},"institutions":[{"id":"https://openalex.org/I2799546111","display_name":"Roskilde Sygehus","ror":"https://ror.org/00t2n7611","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799546111"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"funder","lineage":["https://openalex.org/I2801498763"]},{"id":"https://openalex.org/I2801827564","display_name":"Herlev Hospital","ror":"https://ror.org/00wys9y90","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801827564","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]},{"id":"https://openalex.org/I4210091196","display_name":"Vejle Sygehus","ror":"https://ror.org/00e8ar137","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I4210091196","https://openalex.org/I4210142184"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"U. Lassen","raw_affiliation_strings":["Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark","institution_ids":["https://openalex.org/I2799546111","https://openalex.org/I2801498763","https://openalex.org/I2801827564","https://openalex.org/I2802709434","https://openalex.org/I4210091196"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070373312","display_name":"Morten Mau\u2010S\u00f8rensen","orcid":"https://orcid.org/0000-0003-2235-1250","observed_orcids":["https://orcid.org/0000-0003-2235-1250"]},"institutions":[{"id":"https://openalex.org/I2799546111","display_name":"Roskilde Sygehus","ror":"https://ror.org/00t2n7611","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799546111"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"funder","lineage":["https://openalex.org/I2801498763"]},{"id":"https://openalex.org/I2801827564","display_name":"Herlev Hospital","ror":"https://ror.org/00wys9y90","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801827564","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]},{"id":"https://openalex.org/I4210091196","display_name":"Vejle Sygehus","ror":"https://ror.org/00e8ar137","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I4210091196","https://openalex.org/I4210142184"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"M. S\u00f8rensen","raw_affiliation_strings":["Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark","institution_ids":["https://openalex.org/I2799546111","https://openalex.org/I2801498763","https://openalex.org/I2801827564","https://openalex.org/I2802709434","https://openalex.org/I4210091196"]}]},{"author_position":"middle","author":{"id":null,"display_name":"P. B. Jensen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799546111","display_name":"Roskilde Sygehus","ror":"https://ror.org/00t2n7611","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799546111"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"funder","lineage":["https://openalex.org/I2801498763"]},{"id":"https://openalex.org/I2801827564","display_name":"Herlev Hospital","ror":"https://ror.org/00wys9y90","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801827564","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]},{"id":"https://openalex.org/I4210091196","display_name":"Vejle Sygehus","ror":"https://ror.org/00e8ar137","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I4210091196","https://openalex.org/I4210142184"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"P. B. Jensen","raw_affiliation_strings":["Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark","institution_ids":["https://openalex.org/I2799546111","https://openalex.org/I2801498763","https://openalex.org/I2801827564","https://openalex.org/I2802709434","https://openalex.org/I4210091196"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061738554","display_name":"Seppo Wang Langer","orcid":"https://orcid.org/0000-0001-9732-9192","observed_orcids":["https://orcid.org/0000-0001-9732-9192"]},"institutions":[{"id":"https://openalex.org/I2799546111","display_name":"Roskilde Sygehus","ror":"https://ror.org/00t2n7611","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799546111"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"funder","lineage":["https://openalex.org/I2801498763"]},{"id":"https://openalex.org/I2801827564","display_name":"Herlev Hospital","ror":"https://ror.org/00wys9y90","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801827564","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]},{"id":"https://openalex.org/I4210091196","display_name":"Vejle Sygehus","ror":"https://ror.org/00e8ar137","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I4210091196","https://openalex.org/I4210142184"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"S. W. Langer","raw_affiliation_strings":["Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark","institution_ids":["https://openalex.org/I2799546111","https://openalex.org/I2801498763","https://openalex.org/I2801827564","https://openalex.org/I2802709434","https://openalex.org/I4210091196"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083259679","display_name":"Brita Bjerregaard Jensen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799546111","display_name":"Roskilde Sygehus","ror":"https://ror.org/00t2n7611","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799546111"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"funder","lineage":["https://openalex.org/I2801498763"]},{"id":"https://openalex.org/I2801827564","display_name":"Herlev Hospital","ror":"https://ror.org/00wys9y90","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801827564","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]},{"id":"https://openalex.org/I4210091196","display_name":"Vejle Sygehus","ror":"https://ror.org/00e8ar137","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I4210091196","https://openalex.org/I4210142184"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"B. B. Jensen","raw_affiliation_strings":["Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark","institution_ids":["https://openalex.org/I2799546111","https://openalex.org/I2801498763","https://openalex.org/I2801827564","https://openalex.org/I2802709434","https://openalex.org/I4210091196"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022463562","display_name":"Nina Jeppesen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799546111","display_name":"Roskilde Sygehus","ror":"https://ror.org/00t2n7611","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799546111"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"funder","lineage":["https://openalex.org/I2801498763"]},{"id":"https://openalex.org/I2801827564","display_name":"Herlev Hospital","ror":"https://ror.org/00wys9y90","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801827564","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]},{"id":"https://openalex.org/I4210091196","display_name":"Vejle Sygehus","ror":"https://ror.org/00e8ar137","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I4210091196","https://openalex.org/I4210142184"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"N. Jeppesen","raw_affiliation_strings":["Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark","institution_ids":["https://openalex.org/I2799546111","https://openalex.org/I2801498763","https://openalex.org/I2801827564","https://openalex.org/I2802709434","https://openalex.org/I4210091196"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034875580","display_name":"Carsten Rytter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799546111","display_name":"Roskilde Sygehus","ror":"https://ror.org/00t2n7611","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799546111"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"funder","lineage":["https://openalex.org/I2801498763"]},{"id":"https://openalex.org/I2801827564","display_name":"Herlev Hospital","ror":"https://ror.org/00wys9y90","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801827564","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]},{"id":"https://openalex.org/I4210091196","display_name":"Vejle Sygehus","ror":"https://ror.org/00e8ar137","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I4210091196","https://openalex.org/I4210142184"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"C. Rytter","raw_affiliation_strings":["Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark","institution_ids":["https://openalex.org/I2799546111","https://openalex.org/I2801498763","https://openalex.org/I2801827564","https://openalex.org/I2802709434","https://openalex.org/I4210091196"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049829108","display_name":"Anders Mellemgaard","orcid":"https://orcid.org/0000-0002-9712-942X","observed_orcids":["https://orcid.org/0000-0002-9712-942X"]},"institutions":[{"id":"https://openalex.org/I2799546111","display_name":"Roskilde Sygehus","ror":"https://ror.org/00t2n7611","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799546111"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"funder","lineage":["https://openalex.org/I2801498763"]},{"id":"https://openalex.org/I2801827564","display_name":"Herlev Hospital","ror":"https://ror.org/00wys9y90","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801827564","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]},{"id":"https://openalex.org/I4210091196","display_name":"Vejle Sygehus","ror":"https://ror.org/00e8ar137","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I4210091196","https://openalex.org/I4210142184"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"A. Mellemgaard","raw_affiliation_strings":["Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark","institution_ids":["https://openalex.org/I2799546111","https://openalex.org/I2801498763","https://openalex.org/I2801827564","https://openalex.org/I2802709434","https://openalex.org/I4210091196"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049735840","display_name":"Olfred Hansen","orcid":"https://orcid.org/0000-0003-0396-1424","observed_orcids":["https://orcid.org/0000-0003-0396-1424"]},"institutions":[{"id":"https://openalex.org/I2799546111","display_name":"Roskilde Sygehus","ror":"https://ror.org/00t2n7611","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799546111"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"funder","lineage":["https://openalex.org/I2801498763"]},{"id":"https://openalex.org/I2801827564","display_name":"Herlev Hospital","ror":"https://ror.org/00wys9y90","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801827564","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]},{"id":"https://openalex.org/I4210091196","display_name":"Vejle Sygehus","ror":"https://ror.org/00e8ar137","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I4210091196","https://openalex.org/I4210142184"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"O. Hansen","raw_affiliation_strings":["Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark","institution_ids":["https://openalex.org/I2799546111","https://openalex.org/I2801498763","https://openalex.org/I2801827564","https://openalex.org/I2802709434","https://openalex.org/I4210091196"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050957961","display_name":"Kell \u00d8sterlind","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799546111","display_name":"Roskilde Sygehus","ror":"https://ror.org/00t2n7611","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799546111"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"funder","lineage":["https://openalex.org/I2801498763"]},{"id":"https://openalex.org/I2801827564","display_name":"Herlev Hospital","ror":"https://ror.org/00wys9y90","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801827564","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]},{"id":"https://openalex.org/I4210091196","display_name":"Vejle Sygehus","ror":"https://ror.org/00e8ar137","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I4210091196","https://openalex.org/I4210142184"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"K. \u00d8sterlind","raw_affiliation_strings":["Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Finsen Center, Rigshospitalet, Copenhagen, Denmark; S\u00f8nderborg Hospital, S\u00f8nderborg, Denmark; Roskilde Hospital, Roskilde, Denmark; Vejle Hospital, Vejle, Denmark; Hiller\u00f8d Hospital, Hiller\u00f8d, Denmark; Odense University Hospital, Odense, Denmark; Herlev University Hospital, Herlev, Denmark","institution_ids":["https://openalex.org/I2799546111","https://openalex.org/I2801498763","https://openalex.org/I2801827564","https://openalex.org/I2802709434","https://openalex.org/I4210091196"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"22","issue":"14_suppl","first_page":"7207","last_page":"7207"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.9648000001907349,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.9648000001907349,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11845","display_name":"Cancer therapeutics and mechanisms","score":0.030400000512599945,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/topotecan","display_name":"topotecan","score":0.8410000205039978},{"id":"https://openalex.org/keywords/cisplatin","display_name":"cisplatin","score":1.0},{"id":"https://openalex.org/keywords/small-cell-lung-cancer","display_name":"small cell lung cancer","score":0.996999979019165},{"id":"https://openalex.org/keywords/extensive-stage","display_name":"extensive stage","score":0.656000018119812},{"id":"https://openalex.org/keywords/chemotherapy-efficacy","display_name":"chemotherapy efficacy","score":0.5490000247955322},{"id":"https://openalex.org/keywords/neutropenia","display_name":"neutropenia","score":0.800000011920929},{"id":"https://openalex.org/keywords/thrombocytopenia","display_name":"thrombocytopenia","score":0.9580000042915344},{"id":"https://openalex.org/keywords/time-to-progression","display_name":"time to progression","score":0.8199999928474426},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.859000027179718}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8843110799789429},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.7822813391685486},{"id":"https://openalex.org/C2777063308","wikidata":"https://www.wikidata.org/wiki/Q1435822","display_name":"Neutropenia","level":3,"score":0.7091295123100281},{"id":"https://openalex.org/C2781209748","wikidata":"https://www.wikidata.org/wiki/Q419953","display_name":"Topotecan","level":3,"score":0.6348719000816345},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5878418684005737},{"id":"https://openalex.org/C2778239845","wikidata":"https://www.wikidata.org/wiki/Q412415","display_name":"Cisplatin","level":3,"score":0.5796676278114319},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5477854013442993},{"id":"https://openalex.org/C31760486","wikidata":"https://www.wikidata.org/wiki/Q7180990","display_name":"Phases of clinical research","level":3,"score":0.5429033041000366},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.5421948432922363},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.4827236831188202},{"id":"https://openalex.org/C2778850193","wikidata":"https://www.wikidata.org/wiki/Q3775974","display_name":"Febrile neutropenia","level":4,"score":0.4521307647228241},{"id":"https://openalex.org/C2776907518","wikidata":"https://www.wikidata.org/wiki/Q1734165","display_name":"Performance status","level":3,"score":0.4465548098087311},{"id":"https://openalex.org/C2778822529","wikidata":"https://www.wikidata.org/wiki/Q1951525","display_name":"Progressive disease","level":3,"score":0.44655388593673706},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.42628708481788635},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.3884351849555969}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1200/jco.2004.22.14_suppl.7207","doi":"https://doi.org/10.1200/jco.2004.22.14_suppl.7207","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2004.22.14_suppl.7207","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},{"id":"doi:10.1200/jco.2004.22.90140.7207","doi":"https://doi.org/10.1200/jco.2004.22.90140.7207","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2004.22.90140.7207","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/4327b518-a22c-4686-9abc-9a97ac52e293","doi":null,"is_oa":false,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/4327b518-a22c-4686-9abc-9a97ac52e293","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Lassen , U , Sorensen , M , Jensen , PB , Langer , SW , Jensen , BB , Jeppesen , N , Rytter , C , Mellemgaard , A , Hansen , O & Osterlind , K 2004 , ' A phase II study of a 3-day schedule with topotecan and cisplatin every three weeks in patients with previously in treated small cell lung cancer and extensive disease : Final results. ' , Journal of Clinical Oncology , vol. 22 , no. 14 , pp. 667S-667S .","raw_type":"contributionToPeriodical"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2087433743","https://openalex.org/W2038193873","https://openalex.org/W2056724724","https://openalex.org/W2136994222","https://openalex.org/W4232069243","https://openalex.org/W2138416295","https://openalex.org/W2590693394","https://openalex.org/W7097469221","https://openalex.org/W1996976488","https://openalex.org/W2171059946"],"abstract_inverted_index":{"7207":[0],"Background:":[1],"The":[2,177,222,258,276],"role":[3],"of":[4,49,72,103,134,159,272],"campthotecins":[5],"in":[6,170,200,213,291],"small":[7],"cell":[8],"lung":[9],"cancer":[10],"(SCLC)":[11],"is":[12,252,266,278],"emerging,":[13],"and":[14,29,51,59,107,120,174,195,202,205,208,215,231,264,274,286],"5-day":[15,270],"regimens":[16],"with":[17,21,41,67,97,138,181,255,282],"topetecan":[18,50,114],"alone":[19],"or":[20,142],"cisplatin":[22,121],"have":[23],"been":[24,57,168],"shown":[25],"to":[26,33,93,154,225,268,280,300],"be":[27,289],"active":[28,254],"tolerable.":[30],"In":[31],"order":[32],"provide":[34],"a":[35,46,68,82,132,157,292],"more":[36],"feasible":[37],"regimen":[38,48,178,251],"for":[39,131],"patients":[40,96,161,281],"extensive":[42,101,283],"disease":[43,140],"we":[44,60],"developed":[45],"three-day":[47],"cisplatin.":[52,275],"Preliminary":[53],"data":[54,259],"has":[55,167],"previously":[56],"presented":[58],"now":[61,187,288],"present":[62],"the":[63,232,262,269],"final,":[64],"updated":[65,242],"results":[66,243],"median":[69,223,233],"follow-up":[70],"time":[71,224,235],"18":[73],"months.":[74],"This":[75,87],"investigators":[76],"initiated":[77],"study":[78,90,248],"was":[79,91,198,211,220,227,236],"supported":[80],"by":[81],"grant":[83],"from":[84,244],"GlaxoSmithKline.":[85],"Methods:":[86],"phase":[88,246,293],"II":[89,247],"planned":[92],"include":[94],"43":[95,160],"histologically":[98],"confirmed":[99],"SCLC,":[100],"stage":[102,284],"disease,":[104],"age":[105],"18\u201375":[106],"WHO":[108],"performance":[109],"status":[110],"0\u20132.":[111],"Patients":[112,137],"received":[113],"2.0":[115],"mg/m2":[116,123],"on":[117,124],"day":[118,125],"1\u20133":[119],"50":[122],"3,":[126],"repeated":[127],"every":[128],"3":[129,146],"weeks,":[130],"maximum":[133],"6":[135],"cycles.":[136],"progressive":[139],"(PD)":[141],"no-change":[143],"(NC)":[144],"after":[145],"cycles":[147],"go":[148],"off-study.":[149],"Results:":[150],"From":[151],"May":[152],"2001":[153],"September":[155],"2003,":[156],"total":[158],"were":[162,189],"included.":[163],"An":[164],"objective":[165],"response":[166],"observed":[169,212],"74%":[171],"(CR":[172],"16%":[173,201],"PR":[175],"58%).":[176],"seems":[179],"tolerable":[180],"no":[182,190],"significant":[183,297],"non-haematological":[184],"toxicity.":[185,257],"Until":[186],"there":[188],"toxic":[191],"deaths.":[192],"Grade":[193],"III":[194,207,294],"IV":[196,209],"neutropenia":[197],"seen":[199],"9%,":[203],"respectively,":[204],"grade":[206],"thrombocytopenia":[210],"3%":[214],"3%,":[216],"respectively.":[217],"Non-hematological":[218],"toxicity":[219,265],"mild.":[221],"progression":[226],"7.3":[228],"months":[229,238],"(5.9\u20138.7),":[230],"survival":[234],"10.3":[237],"(8.4\u201311.9).":[239],"Conclusions:":[240],"These":[241],"this":[245,250],"indicate":[249],"very":[253],"limited":[256],"suggest":[260],"that":[261],"efficacy":[263],"similar":[267],"schedule":[271,277],"topotecan":[273],"attractive":[279],"SCLC":[285],"will":[287],"evaluated":[290],"study.":[295],"No":[296],"financial":[298],"relationships":[299],"disclose.":[301]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-04-14T00:00:00"}