{"id":"https://openalex.org/W2603572226","doi":"https://doi.org/10.1200/jco.2017.35.4_suppl.305","title":"Analysis of prior malignancies in patients with cholangiocarcinoma.","display_name":"Analysis of prior malignancies in patients with cholangiocarcinoma.","publication_year":2017,"publication_date":"2017-02-01","ids":{"openalex":"https://openalex.org/W2603572226","doi":"https://doi.org/10.1200/jco.2017.35.4_suppl.305","mag":"2603572226"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2017.35.4_suppl.305","doi":"https://doi.org/10.1200/jco.2017.35.4_suppl.305","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2017.35.4_suppl.305","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086692654","display_name":"Taryn Mary Boucher","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Taryn Mary Boucher","raw_affiliation_strings":["Memorial Sloan Kettering Cancer Center, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan Kettering Cancer Center, New York, NY;","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069644669","display_name":"Nancy E. Kemeny","orcid":"https://orcid.org/0000-0002-0929-9542","observed_orcids":["https://orcid.org/0000-0002-0929-9542"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy E. Kemeny","raw_affiliation_strings":["Memorial Sloan Kettering Cancer Center, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan Kettering Cancer Center, New York, NY;","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038396374","display_name":"Joanne F. Chou","orcid":"https://orcid.org/0000-0002-6866-2022","observed_orcids":["https://orcid.org/0000-0002-6866-2022"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joanne F. Chou","raw_affiliation_strings":["Memorial Sloan-Kettering Cancer Center, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, NY;","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045756365","display_name":"Marinela Capanu","orcid":"https://orcid.org/0000-0003-4953-3193","observed_orcids":["https://orcid.org/0000-0003-4953-3193"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marinela Capanu","raw_affiliation_strings":["Memorial Sloan Kettering Cancer Center, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan Kettering Cancer Center, New York, NY;","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057803141","display_name":"Maeve Aine Lowery","orcid":"https://orcid.org/0000-0003-1354-7606","observed_orcids":["https://orcid.org/0000-0003-1354-7606"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maeve Aine Lowery","raw_affiliation_strings":["Memorial Sloan Kettering Cancer Center, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan Kettering Cancer Center, New York, NY;","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031539570","display_name":"Andrea Cercek","orcid":"https://orcid.org/0000-0002-5054-8192","observed_orcids":["https://orcid.org/0000-0002-5054-8192"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrea Cercek","raw_affiliation_strings":["Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1334819555"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"35","issue":"4_suppl","first_page":"305","last_page":"305"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11364","display_name":"Cholangiocarcinoma and Gallbladder Cancer Studies","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11364","display_name":"Cholangiocarcinoma and Gallbladder Cancer Studies","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14078","display_name":"Multiple and Secondary Primary Cancers","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12460","display_name":"Pediatric Hepatobiliary Diseases and Treatments","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cholangiocarcinoma","display_name":"cholangiocarcinoma","score":0.9990000128746033},{"id":"https://openalex.org/keywords/prior-malignancy","display_name":"prior malignancy","score":0.8159999847412109},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.7360000014305115},{"id":"https://openalex.org/keywords/intrahepatic-cholangiocarcinoma","display_name":"intrahepatic cholangiocarcinoma","score":0.8920000195503235},{"id":"https://openalex.org/keywords/extrahepatic-cholangiocarcinoma","display_name":"extrahepatic cholangiocarcinoma","score":0.8600000143051147},{"id":"https://openalex.org/keywords/secondary-malignancies","display_name":"secondary malignancies","score":0.49399998784065247},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.49399998784065247},{"id":"https://openalex.org/keywords/chemotherapy","display_name":"chemotherapy","score":0.7860000133514404},{"id":"https://openalex.org/keywords/hormone-receptor-status","display_name":"hormone receptor status","score":0.6940000057220459},{"id":"https://openalex.org/keywords/her2-status","display_name":"HER2 status","score":0.9039999842643738},{"id":"https://openalex.org/keywords/female-patients","display_name":"female patients","score":0.47999998927116394},{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.4189999997615814},{"id":"https://openalex.org/keywords/melanoma","display_name":"melanoma","score":0.9829999804496765},{"id":"https://openalex.org/keywords/ovarian-cancer","display_name":"ovarian cancer","score":0.9879999756813049}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9425525665283203},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.63083815574646},{"id":"https://openalex.org/C2909135397","wikidata":"https://www.wikidata.org/wiki/Q124292","display_name":"Intrahepatic Cholangiocarcinoma","level":2,"score":0.589177668094635},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5737345814704895},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5522593259811401},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.44564709067344666},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.43985825777053833},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3480268716812134}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1200/jco.2017.35.4_suppl.305","doi":"https://doi.org/10.1200/jco.2017.35.4_suppl.305","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2017.35.4_suppl.305","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4313063279","https://openalex.org/W4214750299","https://openalex.org/W3028781903","https://openalex.org/W7223185282","https://openalex.org/W2073588888","https://openalex.org/W2559827642","https://openalex.org/W1003544125","https://openalex.org/W150586073","https://openalex.org/W4381949141","https://openalex.org/W2916211970"],"abstract_inverted_index":{"305":[0],"Background:":[1],"Cholangiocarcinomas":[2],"account":[3],"for":[4,258],"approximately":[5],"3%":[6],"of":[7,16,51,68,86,143,178,185,205,222,232,300,309,317,331,345,355],"gastrointestinal":[8],"tumors.":[9],"Our":[10],"aim":[11],"was":[12,38,124,172,210,237],"to":[13,40,53,208,322,350],"analyze":[14],"types":[15,221],"prior":[17,31,165,186,195,206,223,246,318],"malignancies":[18,224],"in":[19,28,315,338],"patients":[20],"(pts)":[21],"with":[22,24,30,47,77,94,163,193,245,294,303,340],"cholangiocarcinoma,":[23,83,95,295],"a":[25,84,141,194,298,307,343,352],"special":[26],"interest":[27],"pts":[29,44,71,76,88,93,162,192,244,264,280,293,339],"breast":[32,233,247,260,310,319,346],"cancer.":[33,261,311],"Methods:":[34],"An":[35,329],"IRB":[36],"waiver":[37],"obtained":[39],"retrospectively":[41],"review":[42],"female":[43,70,292],"who":[45,265,281],"presented":[46],"an":[48],"initial":[49],"diagnosis":[50,123,204,231],"cholangiocarcinoma":[52,122,179,209,236,341],"Memorial":[54],"Sloan":[55],"Kettering":[56],"Cancer":[57],"Center":[58],"between":[59,175,230],"January":[60],"2000":[61],"and":[62,107,112,130,155,183,235,253,273,335,342],"August":[63],"2015.":[64],"Results:":[65],"Medical":[66],"records":[67,79],"804":[69],"were":[72,89,98,132,167,270,275,286],"reviewed.":[73],"After":[74],"excluding":[75],"limited":[78],"or":[80,115],"without":[81],"biopsy-proven":[82],"total":[85],"625":[87,92,136,291],"analyzed.":[90],"Of":[91,134],"506":[96],"(81%)":[97],"intrahepatic":[99],"(ICC),":[100],"85":[101],"(14%)":[102],"hilar,":[103],"24":[104],"(4%)":[105],"extrahepatic":[106],"10":[108],"(2%)":[109],"mixed":[110],"ICC":[111],"hepatocellular":[113],"carcinoma":[114],"rare":[116],"variant.":[117],"The":[118,159,228,312],"median":[119,201],"age":[120],"at":[121],"63":[125],"years":[126],"[range:":[127,213],"16-97":[128],"years]":[129],"82.7%":[131],"white.":[133],"the":[135,176,200],"pts,":[137],"105":[138],"(17%)":[139],"had":[140,266,282,297],"history":[142,299,308,344],"another":[144,301],"cancer:":[145],"44":[146,304],"(7.04%)":[147],"breast,":[148],"9":[149,152],"(1.44%)":[150,153],"colon,":[151],"melanoma":[154],"5":[156],"(0.8%)":[157],"ovarian.":[158],"remaining":[160],"38":[161],"various":[164],"cancers":[166,324],"grouped":[168],"as":[169],"Other.":[170],"There":[171],"no":[173],"association":[174,354],"site":[177],"(intrahepatic":[180],"versus":[181],"extrahepatic)":[182],"type":[184],"cancer":[187,196,207,234,320,347],"(p":[188,225],"=":[189,198,226],"0.26).":[190],"In":[191,243,262,278,290],"(n":[197],"105),":[199],"time":[202],"from":[203],"76":[211],"months":[212,239],"2-624":[214],"months],":[215],"which":[216],"did":[217],"not":[218],"differ":[219],"among":[220],"0.25).":[227],"interval":[229],"82":[238],"[range":[240],"4-526":[241],"months].":[242],"cancer,":[248,302],"21":[249],"(48%)":[250],"received":[251,256],"radiation":[252],"25":[254],"(57%)":[255],"chemotherapy":[257],"their":[259],"22":[263],"ER/PR":[267],"testing,":[268,284],"16":[269],"ER":[271],"positive":[272],"15":[274],"PR":[276],"positive.":[277,288],"17":[279],"HER2":[283,287],"4":[285],"Conclusions:":[289],"17%":[296],"(7%)":[305],"having":[306],"apparent":[313],"increase":[314],"proportions":[316],"compared":[321],"other":[323],"should":[325],"be":[326],"investigated":[327],"further.":[328],"analysis":[330],"tumor":[332],"mutations":[333,337],"(MSK-IMPACT)":[334],"germline":[336],"is":[348],"underway":[349],"determine":[351],"potential":[353],"molecular":[356],"factors.":[357]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2017-04-07T00:00:00"}