{"id":"https://openalex.org/W2602874679","doi":null,"title":"The Emerging Therapeutic Role of Medical Foods for Gastrointestinal Disorders.","display_name":"The Emerging Therapeutic Role of Medical Foods for Gastrointestinal Disorders.","publication_year":2017,"publication_date":"2017-02-01","ids":{"openalex":"https://openalex.org/W2602874679","mag":"2602874679","pmid":"https://pubmed.ncbi.nlm.nih.gov/28450817","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5402682"},"language":"en","primary_location":{"id":"pmid:28450817","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28450817","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology & hepatology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5402682/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091559987","display_name":"Brian Ciampa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian P Ciampa","raw_affiliation_strings":["Dr Ciampa and Dr Reyes Ramos are gastroenterology fellows in the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center and are affiliated with Medical Faculty Associates, both in Washington, DC. Dr Borum is a professor of medicine at George Washington University School of Medicine in Washington, DC; director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center; and is affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine","George Washington University, Washington, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dr Ciampa and Dr Reyes Ramos are gastroenterology fellows in the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center and are affiliated with Medical Faculty Associates, both in Washington, DC. Dr Borum is a professor of medicine at George Washington University School of Medicine in Washington, DC; director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center; and is affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine","institution_ids":["https://openalex.org/I193531525"]},{"raw_affiliation_string":"George Washington University, Washington, United States","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028821912","display_name":"Emmanuel Reyes Ramos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emmanuel Reyes Ramos","raw_affiliation_strings":["Dr Ciampa and Dr Reyes Ramos are gastroenterology fellows in the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center and are affiliated with Medical Faculty Associates, both in Washington, DC. Dr Borum is a professor of medicine at George Washington University School of Medicine in Washington, DC; director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center; and is affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine","director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dr Ciampa and Dr Reyes Ramos are gastroenterology fellows in the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center and are affiliated with Medical Faculty Associates, both in Washington, DC. Dr Borum is a professor of medicine at George Washington University School of Medicine in Washington, DC; director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center; and is affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine","institution_ids":["https://openalex.org/I193531525"]},{"raw_affiliation_string":"director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036543584","display_name":"Marie L. Borum","orcid":"https://orcid.org/0000-0001-5328-1991","observed_orcids":["https://orcid.org/0000-0001-5328-1991"]},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marie Borum","raw_affiliation_strings":["Dr Ciampa and Dr Reyes Ramos are gastroenterology fellows in the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center and are affiliated with Medical Faculty Associates, both in Washington, DC. Dr Borum is a professor of medicine at George Washington University School of Medicine in Washington, DC; director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center; and is affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine","and is affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dr Ciampa and Dr Reyes Ramos are gastroenterology fellows in the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center and are affiliated with Medical Faculty Associates, both in Washington, DC. Dr Borum is a professor of medicine at George Washington University School of Medicine in Washington, DC; director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center; and is affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine","institution_ids":["https://openalex.org/I193531525"]},{"raw_affiliation_string":"and is affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"last","author":{"id":null,"display_name":"David B Doman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David B Doman","raw_affiliation_strings":["Dr Ciampa and Dr Reyes Ramos are gastroenterology fellows in the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center and are affiliated with Medical Faculty Associates, both in Washington, DC. Dr Borum is a professor of medicine at George Washington University School of Medicine in Washington, DC; director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center; and is affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dr Ciampa and Dr Reyes Ramos are gastroenterology fellows in the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center and are affiliated with Medical Faculty Associates, both in Washington, DC. Dr Borum is a professor of medicine at George Washington University School of Medicine in Washington, DC; director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center; and is affiliated with Medical Faculty Associates. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine","institution_ids":["https://openalex.org/I193531525"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I193531525"],"apc_list":null,"apc_paid":null,"fwci":2.6195,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.88485739,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"13","issue":"2","first_page":"104","last_page":"115"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.7089999914169312,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.7089999914169312,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.1876000016927719,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.06030000001192093,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/medical-foods","display_name":"medical foods","score":0.9990000128746033},{"id":"https://openalex.org/keywords/gastrointestinal-diseases","display_name":"gastrointestinal diseases","score":0.8529999852180481},{"id":"https://openalex.org/keywords/fda-regulation","display_name":"FDA regulation","score":0.4830000102519989},{"id":"https://openalex.org/keywords/bovine-immunoglobulins","display_name":"bovine immunoglobulins","score":0.9319999814033508},{"id":"https://openalex.org/keywords/vsl-3","display_name":"VSL#3","score":0.8650000095367432},{"id":"https://openalex.org/keywords/probiotics","display_name":"probiotics","score":0.9769999980926514},{"id":"https://openalex.org/keywords/pouchitis","display_name":"pouchitis","score":0.8980000019073486},{"id":"https://openalex.org/keywords/ulcerative-colitis","display_name":"ulcerative colitis","score":0.9139999747276306},{"id":"https://openalex.org/keywords/crohn-s-disease","display_name":"Crohn's disease","score":0.8980000019073486},{"id":"https://openalex.org/keywords/elemental-diet","display_name":"elemental diet","score":0.9829999804496765},{"id":"https://openalex.org/keywords/irritable-bowel-syndrome","display_name":"irritable bowel syndrome","score":0.9020000100135803},{"id":"https://openalex.org/keywords/inflammatory-bowel-disease","display_name":"inflammatory bowel disease","score":0.847000002861023},{"id":"https://openalex.org/keywords/hiv-associated-enteropathy","display_name":"HIV-associated enteropathy","score":0.8980000019073486},{"id":"https://openalex.org/keywords/dietary-management","display_name":"dietary management","score":0.49000000953674316}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8089884519577026},{"id":"https://openalex.org/C2778271842","wikidata":"https://www.wikidata.org/wiki/Q838966","display_name":"Irritable bowel syndrome","level":2,"score":0.7819687128067017},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6678332090377808},{"id":"https://openalex.org/C2778260677","wikidata":"https://www.wikidata.org/wiki/Q917447","display_name":"Inflammatory bowel disease","level":3,"score":0.5408108830451965},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5280236601829529},{"id":"https://openalex.org/C2778099472","wikidata":"https://www.wikidata.org/wiki/Q2300099","display_name":"Gastrointestinal disease","level":3,"score":0.4845639765262604},{"id":"https://openalex.org/C2778426112","wikidata":"https://www.wikidata.org/wiki/Q3055380","display_name":"Enteropathy","level":3,"score":0.46060875058174133},{"id":"https://openalex.org/C3018890749","wikidata":"https://www.wikidata.org/wiki/Q204711","display_name":"Food and drug administration","level":2,"score":0.44014281034469604},{"id":"https://openalex.org/C2779454807","wikidata":"https://www.wikidata.org/wiki/Q3392956","display_name":"Pouchitis","level":4,"score":0.433938592672348},{"id":"https://openalex.org/C2779802037","wikidata":"https://www.wikidata.org/wiki/Q40878","display_name":"Diarrhea","level":2,"score":0.43337082862854004},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3215276002883911},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.1452910304069519}],"mesh":[],"locations_count":3,"locations":[{"id":"pmid:28450817","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28450817","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology & hepatology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5402682","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5402682/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterol Hepatol (N Y)","raw_type":"Text"},{"id":"mag:2602874679","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28450817","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:5402682","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5402682/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterol Hepatol (N Y)","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":75,"referenced_works":["https://openalex.org/W38835219","https://openalex.org/W102860328","https://openalex.org/W107933407","https://openalex.org/W113095018","https://openalex.org/W283955422","https://openalex.org/W300847501","https://openalex.org/W1603795156","https://openalex.org/W1605188970","https://openalex.org/W1831034353","https://openalex.org/W1892800907","https://openalex.org/W1932727195","https://openalex.org/W1968246688","https://openalex.org/W1970317364","https://openalex.org/W1975223726","https://openalex.org/W1976195770","https://openalex.org/W1977661196","https://openalex.org/W1977738425","https://openalex.org/W1980154502","https://openalex.org/W1984974780","https://openalex.org/W1991579452","https://openalex.org/W1998335236","https://openalex.org/W2000815718","https://openalex.org/W2005735626","https://openalex.org/W2008291093","https://openalex.org/W2008562017","https://openalex.org/W2009724164","https://openalex.org/W2010235735","https://openalex.org/W2011925705","https://openalex.org/W2015078763","https://openalex.org/W2030440711","https://openalex.org/W2042063433","https://openalex.org/W2047033934","https://openalex.org/W2051354338","https://openalex.org/W2051586762","https://openalex.org/W2054552132","https://openalex.org/W2055192920","https://openalex.org/W2056548679","https://openalex.org/W2060202228","https://openalex.org/W2063258052","https://openalex.org/W2063594602","https://openalex.org/W2070376189","https://openalex.org/W2071746741","https://openalex.org/W2072266456","https://openalex.org/W2073525362","https://openalex.org/W2075282196","https://openalex.org/W2078268207","https://openalex.org/W2079315433","https://openalex.org/W2082253267","https://openalex.org/W2084645661","https://openalex.org/W2086776132","https://openalex.org/W2098646733","https://openalex.org/W2101003324","https://openalex.org/W2105772032","https://openalex.org/W2108927902","https://openalex.org/W2124683343","https://openalex.org/W2126110907","https://openalex.org/W2132984860","https://openalex.org/W2136269756","https://openalex.org/W2139387284","https://openalex.org/W2151088711","https://openalex.org/W2162571078","https://openalex.org/W2164045115","https://openalex.org/W2175732964","https://openalex.org/W2262749458","https://openalex.org/W2283032163","https://openalex.org/W2321650211","https://openalex.org/W2325444022","https://openalex.org/W2407156020","https://openalex.org/W2408924638","https://openalex.org/W2410013801","https://openalex.org/W2417241705","https://openalex.org/W2426396460","https://openalex.org/W2463650067","https://openalex.org/W2518632055","https://openalex.org/W4243751265"],"related_works":["https://openalex.org/W2767769708","https://openalex.org/W1513732035","https://openalex.org/W2082253267","https://openalex.org/W4400864499","https://openalex.org/W2977595072","https://openalex.org/W4236179464","https://openalex.org/W2523210369","https://openalex.org/W7101094057","https://openalex.org/W4214729244","https://openalex.org/W7163066071"],"abstract_inverted_index":{"In":[0],"addition":[1,214],"to":[2,24,35,44,91,103,157,194,215,239],"drugs":[3],"approved":[4],"by":[5,82],"the":[6,36,51,61,159,222,230,244],"US":[7],"Food":[8],"and":[9,29,56,126,187,201,224,232],"Drug":[10],"Administration":[11],"(FDA)":[12],"that":[13,41,57,133,170,207],"treat,":[14],"cure,":[15],"or":[16,47,68,212],"mitigate":[17],"disease,":[18],"medical":[19,32,83,88,98,217,227,236],"foods":[20,89,184,228,237],"are":[21,80,185],"a":[22,39,54,66,94,131,152,174,196],"tool":[23],"help":[25,92,240],"manage":[26,93,158,195,241],"chronic":[27],"conditions":[28,200],"diseases.":[30,202],"A":[31,85],"food,":[33],"according":[34],"FDA,":[37],"is":[38,42,58,130,134,151,166,171],"food":[40],"developed":[43],"be":[45,209],"eaten":[46],"administered":[48],"enterally":[49],"under":[50,229],"guidance":[52],"of":[53,65,87,97,162,176,198,226,243],"physician":[55],"meant":[59],"for":[60,70,138],"specific":[62],"dietary":[63],"management":[64],"condition":[67],"disease":[69,102,124],"which":[71,112],"distinctive":[72],"nutritional":[73],"requirements,":[74],"based":[75],"upon":[76],"known":[77],"scientific":[78],"principles,":[79],"established":[81],"evaluation.":[84],"variety":[86,175,197],"exist":[90],"wide":[95],"range":[96],"conditions,":[99],"from":[100],"Alzheimer":[101],"HIV-associated":[104,127],"enteropathy.":[105,128],"EnteraGam":[106],"contains":[107],"serum-derived":[108],"bovine":[109],"immunoglobulin/protein":[110],"isolate,":[111],"has":[113],"been":[114],"studied":[115],"extensively":[116],"in":[117,136,173,192,213],"diarrhea-predominant":[118],"irritable":[119,146],"bowel":[120,123,147],"syndrome,":[121],"inflammatory":[122],"(IBD),":[125],"VSL#3":[129],"probiotic":[132],"used":[135,156,172,210,238],"pouchitis":[137],"patients":[139],"with":[140,179],"ulcerative":[141],"colitis":[142],"as":[143,145],"well":[144],"syndrome.":[148],"Modulen":[149],"IBD":[150],"whole-protein,":[153],"sole-nutrition":[154],"formulation":[155],"active":[160],"phase":[161],"Crohn's":[163],"disease.":[164],"Vivonex":[165],"an":[167],"elemental":[168],"diet":[169],"diseases":[177,242],"associated":[178],"severe":[180],"gastrointestinal":[181,199,245],"dysfunction.":[182],"Medical":[183],"safe":[186],"must":[188],"have":[189],"proven":[190],"efficacy":[191],"helping":[193],"These":[203],"therapies":[204],"represent":[205],"tools":[206],"can":[208],"prior":[211],"traditional":[216],"therapies.":[218],"This":[219],"article":[220],"discusses":[221],"history":[223],"development":[225],"FDA":[231],"concentrates":[233],"specifically":[234],"on":[235],"tract.":[246]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2017-04-07T00:00:00"}
