{"id":"https://openalex.org/W2601003545","doi":"https://doi.org/10.1080/21678421.2017.1300287","title":"Association of fractures with the incidence of amyotrophic lateral sclerosis","display_name":"Association of fractures with the incidence of amyotrophic lateral sclerosis","publication_year":2017,"publication_date":"2017-03-20","ids":{"openalex":"https://openalex.org/W2601003545","doi":"https://doi.org/10.1080/21678421.2017.1300287","mag":"2601003545","pmid":"https://pubmed.ncbi.nlm.nih.gov/28316249"},"language":"en","primary_location":{"id":"doi:10.1080/21678421.2017.1300287","doi":"https://doi.org/10.1080/21678421.2017.1300287","is_oa":false,"landing_page_url":"https://doi.org/10.1080/21678421.2017.1300287","pdf_url":null,"source":{"id":"https://openalex.org/S4210172367","display_name":"Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration","issn_l":"2167-8421","issn":["2167-8421","2167-9223"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5527744","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021276559","display_name":"Tracy L. Peters","orcid":"https://orcid.org/0000-0002-0326-5165","observed_orcids":["https://orcid.org/0000-0002-0326-5165"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["SE","US"],"is_corresponding":true,"raw_author_name":"Tracy L. Peters","raw_affiliation_strings":["Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden,","Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden,","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA, and","institution_ids":["https://openalex.org/I4210095140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110988499","display_name":"Caroline E. Weibull","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Caroline E. Weibull","raw_affiliation_strings":["Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden,","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100386859","display_name":"Fang Fang","orcid":"https://orcid.org/0000-0002-3310-6456","observed_orcids":["https://orcid.org/0000-0002-3310-6456","https://orcid.org/0000-0002-2252-2606"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Fang Fang","raw_affiliation_strings":["Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden,","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058634982","display_name":"Dale P. Sandler","orcid":"https://orcid.org/0000-0002-6776-0018","observed_orcids":["https://orcid.org/0000-0002-6776-0018"]},"institutions":[{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dale P. Sandler","raw_affiliation_strings":["Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA, and","institution_ids":["https://openalex.org/I4210095140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002389217","display_name":"Paul C. Lambert","orcid":"https://orcid.org/0000-0002-5337-663X","observed_orcids":["https://orcid.org/0000-0002-5337-663X"]},"institutions":[{"id":"https://openalex.org/I153648349","display_name":"University of Leicester","ror":"https://ror.org/04h699437","country_code":"GB","type":"education","lineage":["https://openalex.org/I153648349"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["GB","SE"],"is_corresponding":false,"raw_author_name":"Paul C. Lambert","raw_affiliation_strings":["Department of Health Sciences, University of Leicester, Leicester, UK","Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Sciences, University of Leicester, Leicester, UK","institution_ids":["https://openalex.org/I153648349"]},{"raw_affiliation_string":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden,","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100601148","display_name":"Weimin Ye","orcid":"https://orcid.org/0000-0002-6859-4648","observed_orcids":["https://orcid.org/0000-0002-6859-4648"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Weimin Ye","raw_affiliation_strings":["Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden,","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074555486","display_name":"Freya Kamel","orcid":"https://orcid.org/0000-0001-5052-6615","observed_orcids":["https://orcid.org/0000-0001-5052-6615"]},"institutions":[{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Freya Kamel","raw_affiliation_strings":["Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA, and","institution_ids":["https://openalex.org/I4210095140"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5021276559"],"corresponding_institution_ids":["https://openalex.org/I28166907","https://openalex.org/I4210095140"],"apc_list":null,"apc_paid":null,"fwci":1.1385,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.76831606,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"18","issue":"5-6","first_page":"419","last_page":"425"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.01730000041425228,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11305","display_name":"Amyloidosis: Diagnosis, Treatment, Outcomes","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amyotrophic-lateral-sclerosis","display_name":"amyotrophic lateral sclerosis","score":1.0},{"id":"https://openalex.org/keywords/fracture","display_name":"fracture","score":0.7540000081062317},{"id":"https://openalex.org/keywords/osteoporotic-fractures","display_name":"osteoporotic fractures","score":0.949999988079071},{"id":"https://openalex.org/keywords/traumatic-fractures","display_name":"traumatic fractures","score":0.9729999899864197},{"id":"https://openalex.org/keywords/non-traumatic-fracture","display_name":"non-traumatic fracture","score":0.8679999709129333},{"id":"https://openalex.org/keywords/bone-health","display_name":"bone health","score":0.8090000152587891},{"id":"https://openalex.org/keywords/bone-turnover","display_name":"bone turnover","score":0.8980000019073486},{"id":"https://openalex.org/keywords/als-risk","display_name":"ALS risk","score":0.7110000252723694},{"id":"https://openalex.org/keywords/fracture-timing","display_name":"fracture timing","score":0.3330000042915344}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8673967719078064},{"id":"https://openalex.org/C2780596555","wikidata":"https://www.wikidata.org/wiki/Q206901","display_name":"Amyotrophic lateral sclerosis","level":3,"score":0.7787752151489258},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.7529495358467102},{"id":"https://openalex.org/C73269764","wikidata":"https://www.wikidata.org/wiki/Q954529","display_name":"Poisson regression","level":3,"score":0.719101071357727},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.6862369775772095},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.6369421482086182},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.6176137328147888},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5300816297531128},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.5268351435661316},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.33810722827911377},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.16408315300941467},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.07879486680030823},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013548","descriptor_name":"Sweden","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D013548","descriptor_name":"Sweden","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D013548","descriptor_name":"Sweden","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D013548","descriptor_name":"Sweden","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1080/21678421.2017.1300287","doi":"https://doi.org/10.1080/21678421.2017.1300287","is_oa":false,"landing_page_url":"https://doi.org/10.1080/21678421.2017.1300287","pdf_url":null,"source":{"id":"https://openalex.org/S4210172367","display_name":"Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration","issn_l":"2167-8421","issn":["2167-8421","2167-9223"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration","raw_type":"journal-article"},{"id":"pmid:28316249","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28316249","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Amyotrophic lateral sclerosis & frontotemporal degeneration","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5017567","doi":null,"is_oa":false,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5527744","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5527744","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5527744","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Amyotroph Lateral Scler Frontotemporal Degener","raw_type":"Text"},{"id":"pmh:oai:lra.le.ac.uk:2381/40965","doi":null,"is_oa":true,"landing_page_url":"http://www.tandfonline.com/doi/full/10.1080/21678421.2017.1300287","pdf_url":null,"source":{"id":"https://openalex.org/S4306402365","display_name":"Leicester Research Archive (University of Leicester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I153648349","host_organization_name":"University of Leicester","host_organization_lineage":["https://openalex.org/I153648349"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:5527744","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5527744","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Amyotroph Lateral Scler Frontotemporal Degener","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/1","display_name":"No poverty","score":0.7200000286102295}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G215093573","display_name":null,"funder_award_id":"Z01-ES049005","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"},{"id":"https://openalex.org/G2195053381","display_name":"Alteration of Metabolism in Amyotrophic Lateral Sclerosis","funder_award_id":"2015-03170","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"},{"id":"https://openalex.org/G581692744","display_name":null,"funder_award_id":"80748301","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"},{"id":"https://openalex.org/G9000158628","display_name":null,"funder_award_id":"Z01 ES049005","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320322315","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W125126038","https://openalex.org/W140404186","https://openalex.org/W1494263088","https://openalex.org/W1970283678","https://openalex.org/W1972117569","https://openalex.org/W1983633543","https://openalex.org/W1984648209","https://openalex.org/W1988971310","https://openalex.org/W1989486717","https://openalex.org/W1990425745","https://openalex.org/W1996259832","https://openalex.org/W2004638767","https://openalex.org/W2006116419","https://openalex.org/W2013480713","https://openalex.org/W2016344011","https://openalex.org/W2032751618","https://openalex.org/W2034427836","https://openalex.org/W2036455067","https://openalex.org/W2046129246","https://openalex.org/W2047606959","https://openalex.org/W2048394599","https://openalex.org/W2049355027","https://openalex.org/W2050626075","https://openalex.org/W2051005295","https://openalex.org/W2054551850","https://openalex.org/W2056207843","https://openalex.org/W2061934895","https://openalex.org/W2066203997","https://openalex.org/W2066846018","https://openalex.org/W2069891325","https://openalex.org/W2075324214","https://openalex.org/W2078379881","https://openalex.org/W2080382496","https://openalex.org/W2112964941","https://openalex.org/W2125287424","https://openalex.org/W2127964855","https://openalex.org/W2142695526","https://openalex.org/W2155190238","https://openalex.org/W2166018731","https://openalex.org/W2166723939","https://openalex.org/W2167568122","https://openalex.org/W2167880717","https://openalex.org/W2233885014","https://openalex.org/W2259069722","https://openalex.org/W2412885977","https://openalex.org/W4247740476"],"related_works":["https://openalex.org/W3094059650","https://openalex.org/W2006003309","https://openalex.org/W2133235702","https://openalex.org/W2889061495","https://openalex.org/W2119154902","https://openalex.org/W2203903734","https://openalex.org/W2917746345","https://openalex.org/W1727188710","https://openalex.org/W3015397552","https://openalex.org/W2323079027"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Elevated":[1],"bone":[2,10,174],"turnover":[3],"observed":[4],"in":[5],"ALS":[6,25,38,51,91,147,170,187],"patients":[7],"suggests":[8],"poor":[9],"health":[11,175],"and":[12,36,39,57,60,62,81,130],"increased":[13],"fracture":[14,22,95],"risk.":[15,26],"We":[16,28,47,70,86],"therefore":[17],"evaluated":[18],"the":[19,42,88],"relationship":[20],"of":[21,50,90,144],"to":[23,34,76,161,179],"subsequent":[24],"METHODS:":[27],"followed":[29],"4,529,460":[30],"Swedes":[31],"from":[32,41,154],"1987":[33],"2010":[35],"identified":[37],"fractures":[40,64,103,137,152],"Swedish":[43],"National":[44],"Patient":[45],"Register.":[46],"examined":[48],"associations":[49],"risk":[52],"with":[53,92,140,151],"all":[54],"fractures,":[55,59],"osteoporotic":[56,112],"non-osteoporotic":[58,118],"traumatic":[61,124],"non-traumatic":[63,131],"among":[65],"individuals":[66],"aged":[67],"30-80":[68],"years.":[69],"used":[71],"Cox":[72],"proportional":[73],"hazards":[74],"models":[75],"estimate":[77],"hazard":[78],"ratios":[79],"(HRs)":[80],"95%":[82,106,115,121,127,134,158,165],"confidence":[83],"intervals":[84],"(CIs).":[85],"analysed":[87],"association":[89],"time":[93],"since":[94],"using":[96],"a":[97,141],"Poisson":[98],"regression":[99],"model.":[100],"RESULTS:":[101],"All":[102],"(HR:":[104,113,119,125,132,156,163],"1.51,":[105],"CI":[107,116,122,128,135,159,166],"1.39-1.65)":[108],"as":[109,111],"well":[110],"1.59,":[114],"1.41-1.79),":[117],"1.46,":[120],"1.31-1.63),":[123],"1.50,":[126],"1.37-1.63),":[129],"1.80,":[133],"1.35-2.40)":[136],"were":[138],"associated":[139,150],"higher":[142],"incidence":[143,148],"ALS.":[145,180],"Increased":[146],"was":[149],"occurring":[153],"one":[155],"2.33,":[157],"2.04-2.66)":[160],"18":[162],"1.19,":[164],"1.01-1.43)":[167],"years":[168],"before":[169],"diagnosis.":[171],"CONCLUSIONS:":[172],"Poor":[173],"may":[176,183],"be":[177],"related":[178],"These":[181],"findings":[182],"offer":[184],"insight":[185],"into":[186],"pathophysiology.":[188]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":6},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}