{"id":"https://openalex.org/W2600430380","doi":null,"title":"Experimental Models of Brain Hemorrhage Using Clostridial Collagenase","display_name":"Experimental Models of Brain Hemorrhage Using Clostridial Collagenase","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2600430380","mag":"2600430380"},"language":"en","primary_location":{"id":"pmh:oai:scholarsrepository.llu.edu:etd-1165","doi":null,"is_oa":true,"landing_page_url":"https://scholarsrepository.llu.edu/etd/166","pdf_url":"https://scholarsrepository.llu.edu/cgi/viewcontent.cgi?article=1165&context=etd","source":{"id":"https://openalex.org/S4377196700","display_name":"The Scholars Repository - LLU (Loma Linda University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I26347476","host_organization_name":"Loma Linda University","host_organization_lineage":["https://openalex.org/I26347476"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Loma Linda University Electronic Theses, Dissertations & Projects","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://scholarsrepository.llu.edu/cgi/viewcontent.cgi?article=1165&context=etd","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011573716","display_name":"Tim Lekic","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Tim Lekic","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5011573716"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intracerebral-hemorrhage","display_name":"intracerebral hemorrhage","score":0.996999979019165},{"id":"https://openalex.org/keywords/animal-models","display_name":"animal models","score":0.6740000247955322},{"id":"https://openalex.org/keywords/cerebellar-hemorrhage","display_name":"cerebellar hemorrhage","score":0.8939999938011169},{"id":"https://openalex.org/keywords/pontine-hemorrhage","display_name":"pontine hemorrhage","score":0.9980000257492065},{"id":"https://openalex.org/keywords/neonatal-hemorrhage","display_name":"neonatal hemorrhage","score":0.777999997138977},{"id":"https://openalex.org/keywords/postpartum-hemorrhage","display_name":"postpartum hemorrhage","score":0.9120000004768372},{"id":"https://openalex.org/keywords/neurobehavioral-outcomes","display_name":"neurobehavioral outcomes","score":0.9430000185966492},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.9049999713897705}],"concepts":[{"id":"https://openalex.org/C2778394429","wikidata":"https://www.wikidata.org/wiki/Q304956","display_name":"Collagenase","level":3,"score":0.45021891593933105},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39155542850494385},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.38594427704811096},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21577727794647217},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.1540524661540985}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:scholarsrepository.llu.edu:etd-1165","doi":null,"is_oa":true,"landing_page_url":"https://scholarsrepository.llu.edu/etd/166","pdf_url":"https://scholarsrepository.llu.edu/cgi/viewcontent.cgi?article=1165&context=etd","source":{"id":"https://openalex.org/S4377196700","display_name":"The Scholars Repository - LLU (Loma Linda University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I26347476","host_organization_name":"Loma Linda University","host_organization_lineage":["https://openalex.org/I26347476"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Loma Linda University Electronic Theses, Dissertations & Projects","raw_type":"text"},{"id":"mag:2600430380","doi":null,"is_oa":false,"landing_page_url":"https://scholarsrepository.llu.edu/cgi/viewcontent.cgi?article=1165&context=etd","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:scholarsrepository.llu.edu:etd-1165","doi":null,"is_oa":true,"landing_page_url":"https://scholarsrepository.llu.edu/etd/166","pdf_url":"https://scholarsrepository.llu.edu/cgi/viewcontent.cgi?article=1165&context=etd","source":{"id":"https://openalex.org/S4377196700","display_name":"The Scholars Repository - LLU (Loma Linda University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I26347476","host_organization_name":"Loma Linda University","host_organization_lineage":["https://openalex.org/I26347476"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Loma Linda University Electronic Theses, Dissertations & Projects","raw_type":"text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306101","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2600430380.pdf","grobid_xml":"https://content.openalex.org/works/W2600430380.grobid-xml"},"referenced_works_count":164,"referenced_works":["https://openalex.org/W47663938","https://openalex.org/W128151115","https://openalex.org/W1488527120","https://openalex.org/W1493139793","https://openalex.org/W1509395915","https://openalex.org/W1947113872","https://openalex.org/W1963751683","https://openalex.org/W1965159556","https://openalex.org/W1968021864","https://openalex.org/W1968869536","https://openalex.org/W1969467371","https://openalex.org/W1971156281","https://openalex.org/W1972477306","https://openalex.org/W1972838566","https://openalex.org/W1973589135","https://openalex.org/W1975737948","https://openalex.org/W1976478686","https://openalex.org/W1979008656","https://openalex.org/W1979711769","https://openalex.org/W1980300082","https://openalex.org/W1981194197","https://openalex.org/W1981615742","https://openalex.org/W1982561027","https://openalex.org/W1988648579","https://openalex.org/W1992521626","https://openalex.org/W1992759272","https://openalex.org/W1993569783","https://openalex.org/W1995177006","https://openalex.org/W1996003447","https://openalex.org/W1997007734","https://openalex.org/W1997733896","https://openalex.org/W1998604986","https://openalex.org/W1999646804","https://openalex.org/W2000872859","https://openalex.org/W2006916600","https://openalex.org/W2008793512","https://openalex.org/W2008811389","https://openalex.org/W2009110359","https://openalex.org/W2010107876","https://openalex.org/W2012977952","https://openalex.org/W2013076830","https://openalex.org/W2014143315","https://openalex.org/W2016897470","https://openalex.org/W2016996899","https://openalex.org/W2018858842","https://openalex.org/W2018929043","https://openalex.org/W2020732144","https://openalex.org/W2021327381","https://openalex.org/W2022523934","https://openalex.org/W2022779476","https://openalex.org/W2023107516","https://openalex.org/W2023318990","https://openalex.org/W2026573219","https://openalex.org/W2028531319","https://openalex.org/W2028619376","https://openalex.org/W2030142544","https://openalex.org/W2030529426","https://openalex.org/W2030587046","https://openalex.org/W2032035911","https://openalex.org/W2039528800","https://openalex.org/W2040126975","https://openalex.org/W2040841545","https://openalex.org/W2041077342","https://openalex.org/W2041467804","https://openalex.org/W2043394084","https://openalex.org/W2046445123","https://openalex.org/W2049310319","https://openalex.org/W2049486947","https://openalex.org/W2049905246","https://openalex.org/W2054058695","https://openalex.org/W2055042536","https://openalex.org/W2056094715","https://openalex.org/W2058201460","https://openalex.org/W2061714758","https://openalex.org/W2062446993","https://openalex.org/W2064387526","https://openalex.org/W2067345938","https://openalex.org/W2067456914","https://openalex.org/W2068494079","https://openalex.org/W2069088919","https://openalex.org/W2071890701","https://openalex.org/W2071984852","https://openalex.org/W2073326184","https://openalex.org/W2074658534","https://openalex.org/W2076182555","https://openalex.org/W2078103827","https://openalex.org/W2078859316","https://openalex.org/W2082320618","https://openalex.org/W2085045265","https://openalex.org/W2085963043","https://openalex.org/W2086123509","https://openalex.org/W2086553401","https://openalex.org/W2086676000","https://openalex.org/W2087923797","https://openalex.org/W2088160739","https://openalex.org/W2092283978","https://openalex.org/W2092451514","https://openalex.org/W2094006685","https://openalex.org/W2098308256","https://openalex.org/W2100167607","https://openalex.org/W2105196489","https://openalex.org/W2107257058","https://openalex.org/W2107572795","https://openalex.org/W2108535965","https://openalex.org/W2109621551","https://openalex.org/W2110177703","https://openalex.org/W2112203065","https://openalex.org/W2113631972","https://openalex.org/W2119471696","https://openalex.org/W2122870387","https://openalex.org/W2122901111","https://openalex.org/W2123279305","https://openalex.org/W2123894947","https://openalex.org/W2127521475","https://openalex.org/W2128835572","https://openalex.org/W2131130086","https://openalex.org/W2131608584","https://openalex.org/W2132628514","https://openalex.org/W2138945326","https://openalex.org/W2139592965","https://openalex.org/W2140165969","https://openalex.org/W2140951756","https://openalex.org/W2142177372","https://openalex.org/W2143302321","https://openalex.org/W2144034260","https://openalex.org/W2145485273","https://openalex.org/W2145540445","https://openalex.org/W2145702028","https://openalex.org/W2149503482","https://openalex.org/W2151432761","https://openalex.org/W2151792507","https://openalex.org/W2155074770","https://openalex.org/W2155567879","https://openalex.org/W2156168620","https://openalex.org/W2156589326","https://openalex.org/W2158085968","https://openalex.org/W2160084282","https://openalex.org/W2160183146","https://openalex.org/W2162281122","https://openalex.org/W2164301820","https://openalex.org/W2164846973","https://openalex.org/W2165251895","https://openalex.org/W2166593722","https://openalex.org/W2168127565","https://openalex.org/W2168564266","https://openalex.org/W2169982485","https://openalex.org/W2170172094","https://openalex.org/W2176314897","https://openalex.org/W2286540131","https://openalex.org/W2316474503","https://openalex.org/W2321005553","https://openalex.org/W2321700603","https://openalex.org/W2330235342","https://openalex.org/W2405507755","https://openalex.org/W2409075314","https://openalex.org/W2411911695","https://openalex.org/W2419131597","https://openalex.org/W2442012045","https://openalex.org/W2494490257","https://openalex.org/W2760460727","https://openalex.org/W2783555157","https://openalex.org/W3135443006","https://openalex.org/W4240994847","https://openalex.org/W4387761109"],"related_works":["https://openalex.org/W2962926374","https://openalex.org/W4286856240","https://openalex.org/W2117893550","https://openalex.org/W2962702864","https://openalex.org/W1970012618","https://openalex.org/W2105196489","https://openalex.org/W2525323777","https://openalex.org/W7215137512","https://openalex.org/W3147548718","https://openalex.org/W1981866159"],"abstract_inverted_index":{"Stroke":[0],"is":[1,9,24,30,40],"the":[2,10,16,20,33,57,88,97,108,112],"third":[3],"leading":[4,11],"cause":[5,12],"of":[6,13,37,52,110,114],"death":[7],"and":[8,19,72,86,90],"disability":[14],"in":[15],"United":[17],"States,":[18],"most":[21],"severe":[22],"form":[23],"known":[25],"as":[26],"intracerebral":[27,53,82],"hemorrhage,":[28,66,68],"which":[29],"bleeding":[31],"into":[32],"brain.":[34],"The":[35],"goal":[36],"this":[38],"study":[39],"to":[41,46,81,103],"establish":[42],"novel":[43],"animal":[44,62],"models":[45,77],"buildup":[47],"foundations":[48],"for":[49,56,99,116],"translational":[50,101],"research":[51],"hemorrhage.":[54,75],"We,":[55],"first":[58],"time,":[59],"established":[60,79,96],"four":[61],"models,":[63],"including":[64],"cerebellum":[65],"pontine":[67],"neonatal":[69],"matrix":[70],"hemorrhage":[71,83],"maternal":[73],"postpartum":[74],"Those":[76],"are":[78],"according":[80],"patient":[84,119],"subpopulations,":[85],"characterized":[87],"neurobehavioral":[89],"morphological":[91],"outcomes.":[92],"These":[93],"studies":[94],"have":[95],"requisite":[98],"future":[100],"work":[102],"test":[104],"neuroprotective":[105],"drugs":[106],"with":[107],"aim":[109],"improving":[111],"quality":[113],"life":[115],"these":[117],"vulnerable":[118],"populations.":[120]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-04-07T00:00:00"}