{"id":"https://openalex.org/W2597939001","doi":"https://doi.org/10.1200/jco.2004.22.14_suppl.3013","title":"Rapid decrease in blood flow (BF), blood volume (BV), and vascular permeability (PS) in carcinoid patients treated with bevacizumab","display_name":"Rapid decrease in blood flow (BF), blood volume (BV), and vascular permeability (PS) in carcinoid patients treated with bevacizumab","publication_year":2004,"publication_date":"2004-07-15","ids":{"openalex":"https://openalex.org/W2597939001","doi":"https://doi.org/10.1200/jco.2004.22.14_suppl.3013","mag":"2597939001"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2004.22.14_suppl.3013","doi":"https://doi.org/10.1200/jco.2004.22.14_suppl.3013","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2004.22.14_suppl.3013","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043534982","display_name":"James C. Yao","orcid":"https://orcid.org/0000-0002-1875-3962","observed_orcids":["https://orcid.org/0000-0002-1875-3962"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. C. Yao","raw_affiliation_strings":["University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112810103","display_name":"Chusilp Charnsangavej","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Charnsangavej","raw_affiliation_strings":["University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015276672","display_name":"Silvana Castro Faria","orcid":"https://orcid.org/0000-0001-5998-9034","observed_orcids":["https://orcid.org/0000-0001-5998-9034"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. C. Faria","raw_affiliation_strings":["University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115883309","display_name":"Janio Szklaruk","orcid":"https://orcid.org/0000-0002-2416-2851","observed_orcids":["https://orcid.org/0000-0002-2416-2851"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Szklaruk","raw_affiliation_strings":["University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050235502","display_name":"H. Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Chen","raw_affiliation_strings":["University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072207853","display_name":"Paulo M. Hoff","orcid":"https://orcid.org/0000-0002-0065-2194","observed_orcids":["https://orcid.org/0000-0002-0065-2194"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Hoff","raw_affiliation_strings":["University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066360308","display_name":"Alexandria T. Phan","orcid":"https://orcid.org/0000-0002-2953-3033","observed_orcids":["https://orcid.org/0000-0002-2953-3033"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Phan","raw_affiliation_strings":["University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081791823","display_name":"Sai\u2010Ching J. Yeung","orcid":"https://orcid.org/0000-0001-5170-0822","observed_orcids":["https://orcid.org/0000-0001-5170-0822"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S.-C. J. Yeung","raw_affiliation_strings":["University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110481222","display_name":"James L. Abbruzzese","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. L. Abbruzzese","raw_affiliation_strings":["University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I4210140884"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044064524","display_name":"Jaffer A. Ajani","orcid":"https://orcid.org/0000-0001-9946-0629","observed_orcids":["https://orcid.org/0000-0001-9946-0629"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. A. Ajani","raw_affiliation_strings":["University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas M. D. Anderson Cancer Center, Houston, TX; National Cancer Institute, Bethesda, MD","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I4210140884"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"22","issue":"14_suppl","first_page":"3013","last_page":"3013"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.9326000213623047,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.9326000213623047,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.05009999871253967,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carcinoid-tumor","display_name":"carcinoid tumor","score":0.9409999847412109},{"id":"https://openalex.org/keywords/bevacizumab","display_name":"bevacizumab","score":0.996999979019165},{"id":"https://openalex.org/keywords/anti-angiogenic-therapy","display_name":"anti-angiogenic therapy","score":0.8190000057220459},{"id":"https://openalex.org/keywords/vegf-neutralization","display_name":"VEGF neutralization","score":0.7990000247955322},{"id":"https://openalex.org/keywords/blood-flow","display_name":"blood flow","score":0.6740000247955322},{"id":"https://openalex.org/keywords/blood-volume","display_name":"blood volume","score":0.9559999704360962},{"id":"https://openalex.org/keywords/vascular-permeability","display_name":"vascular permeability","score":0.9380000233650208},{"id":"https://openalex.org/keywords/functional-ct","display_name":"functional CT","score":0.7829999923706055},{"id":"https://openalex.org/keywords/octreotide","display_name":"octreotide","score":0.7889999747276306},{"id":"https://openalex.org/keywords/tumor-response-assessment","display_name":"tumor response assessment","score":0.4169999957084656},{"id":"https://openalex.org/keywords/metastatic-neuroendocrine-tumors","display_name":"metastatic neuroendocrine tumors","score":0.7940000295639038}],"concepts":[{"id":"https://openalex.org/C2777802072","wikidata":"https://www.wikidata.org/wiki/Q413299","display_name":"Bevacizumab","level":3,"score":0.8526471853256226},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7856598496437073},{"id":"https://openalex.org/C2781151469","wikidata":"https://www.wikidata.org/wiki/Q339547","display_name":"Carcinoid syndrome","level":2,"score":0.4738338887691498},{"id":"https://openalex.org/C2779066768","wikidata":"https://www.wikidata.org/wiki/Q1981276","display_name":"Neuroendocrine tumors","level":2,"score":0.47325757145881653},{"id":"https://openalex.org/C2781025020","wikidata":"https://www.wikidata.org/wiki/Q419935","display_name":"Octreotide","level":3,"score":0.45762619376182556},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.4157281517982483},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.3870236277580261},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.30652907490730286},{"id":"https://openalex.org/C2776297358","wikidata":"https://www.wikidata.org/wiki/Q407166","display_name":"Somatostatin","level":2,"score":0.11990135908126831}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1200/jco.2004.22.14_suppl.3013","doi":"https://doi.org/10.1200/jco.2004.22.14_suppl.3013","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2004.22.14_suppl.3013","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},{"id":"doi:10.1200/jco.2004.22.90140.3013","doi":"https://doi.org/10.1200/jco.2004.22.90140.3013","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2004.22.90140.3013","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2249288343","https://openalex.org/W2166100060","https://openalex.org/W1981791928","https://openalex.org/W2231519804","https://openalex.org/W2227384116","https://openalex.org/W1970248216","https://openalex.org/W2117188579","https://openalex.org/W2735552300","https://openalex.org/W2093882050","https://openalex.org/W2241632165"],"abstract_inverted_index":{"3013":[0],"Background:":[1],"Carcinoid":[2],"tumors":[3],"are":[4,26,59,148],"vascular":[5],"and":[6,38,77,93,113,136,163,216,225,244,253],"frequently":[7],"express":[8],"VEGF.":[9],"Effective":[10],"systemic":[11],"therapy":[12,29],"is":[13,81,87,184,201,227],"lacking.":[14],"VEGF":[15,261],"neutralizing":[16],"antibodies":[17],"decrease":[18],"metastases":[19],"in":[20,30,43,131,151,159,171,213,233,240,247,260],"a":[21,31,54,128],"carcinoid":[22,49,234,248],"xenograft":[23],"model.":[24],"We":[25],"evaluating":[27],"anti-angiogenic":[28,263],"phase":[32],"II":[33],"study":[34,224],"of":[35,57,146,154],"bevacizumab":[36],"(BVZ)":[37],"PEG":[39],"interferon":[40],"alpha-2b":[41],"(PEGI)":[42],"patients":[44,73,97,102,206,221,235],"with":[45,125],"metastatic":[46],"or":[47,64],"unresectable":[48],"tumors.":[50],"Methods:":[51],"Patients":[52],"on":[53,106,119,180,197,203,223,228],"stable":[55],"dose":[56,145],"octreotide":[58],"randomly":[60],"assigned":[61],"to":[62,89,190,269],"BVZ":[63,76,120,147,231],"PEGI":[65,182,199],"for":[66,256],"18":[67,71],"weeks.":[68],"After":[69],"initial":[70],"weeks,":[72],"receive":[74],"both":[75],"PEGI.":[78],"Planned":[79],"accrual":[80,226],"44":[82],"patients.":[83],"Functional":[84],"CT":[85],"(fCT)":[86],"used":[88],"monitor":[90],"BF,":[91,161,214,242],"BV,":[92,162,215,243],"PS.":[94,245],"Results:":[95],"Sixteen":[96],"have":[98,103,116],"been":[99,117],"accrued;":[100],"8":[101],"begun":[104],"treatment":[105,232],"each":[107],"arm.":[108],"Radiological":[109],"responses":[110],"(1":[111],"PR":[112],"1":[114],"MR)":[115],"observed":[118,166],"therapy.":[121,264],"One":[122],"additional":[123],"patient":[124],"SD":[126],"had":[127],"78%":[129],"drop":[130],"urine":[132],"5HIAA":[133],"level.":[134],"Baseline":[135],"follow-up":[137,178,193],"scans":[138],"obtained":[139],"48":[140],"hours":[141],"after":[142],"the":[143,152,181,191,198],"first":[144],"being":[149],"reported":[150],"analysis":[153],"antiangiogenic":[155],"effects.":[156],"Rapid":[157],"declines":[158],"tumor":[160,241],"PS":[164,217],"were":[165,218],"(Table).":[167],"No":[168,210,265],"significant":[169,211,266],"change":[170],"mean":[172],"transit":[173],"time":[174],"was":[175],"observed.":[176,219],"First":[177],"fCT":[179,195,246],"arm":[183,200],"performed":[185],"at":[186,207],"week":[187],"9.":[188],"Due":[189],"differing":[192],"schedule,":[194],"data":[196],"available":[202],"only":[204],"2":[205],"this":[208],"time.":[209],"changes":[212],"All":[220],"remain":[222],"going.":[229],"Conclusions:":[230],"consistently":[236],"produced":[237],"rapid":[238],"decline":[239],"may":[249],"be":[250],"an":[251],"effective":[252],"non-invasive":[254],"method":[255],"assessing":[257],"target":[258],"inhibition":[259],"directed":[262],"financial":[267],"relationships":[268],"disclose.":[270]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2017-04-07T00:00:00"}