{"id":"https://openalex.org/W2597072370","doi":"https://doi.org/10.1007/s11136-017-1544-2","title":"Symptom burden and life challenges reported by adult chordoma patients and their caregivers","display_name":"Symptom burden and life challenges reported by adult chordoma patients and their caregivers","publication_year":2017,"publication_date":"2017-03-17","ids":{"openalex":"https://openalex.org/W2597072370","doi":"https://doi.org/10.1007/s11136-017-1544-2","mag":"2597072370","pmid":"https://pubmed.ncbi.nlm.nih.gov/28315176","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5509836"},"language":"en","primary_location":{"id":"doi:10.1007/s11136-017-1544-2","doi":"https://doi.org/10.1007/s11136-017-1544-2","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11136-017-1544-2","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11136-017-1544-2.pdf","source":{"id":"https://openalex.org/S90347677","display_name":"Quality of Life Research","issn_l":"0962-9343","issn":["0962-9343","1573-2649"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["abdc-a","anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","fnege-3","jufo-3","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Quality of Life Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s11136-017-1544-2.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031766760","display_name":"Paula H. Song","orcid":"https://orcid.org/0000-0003-0803-3563","observed_orcids":["https://orcid.org/0000-0003-0803-3563"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Paula H. Song","raw_affiliation_strings":["Department of Health Policy and Management, The University of North Carolina at Chapel Hill, 1105A McGavran-Greenberg Hall, CB #7411, Chapel Hill, NC, 27599-7411, USA. psong@unc.edu","Department of Health Policy and Management, The University of North Carolina at Chapel Hill, 1105A McGavran-Greenberg Hall, CB #7411, Chapel Hill, NC, 27599-7411, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Policy and Management, The University of North Carolina at Chapel Hill, 1105A McGavran-Greenberg Hall, CB #7411, Chapel Hill, NC, 27599-7411, USA. psong@unc.edu","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Department of Health Policy and Management, The University of North Carolina at Chapel Hill, 1105A McGavran-Greenberg Hall, CB #7411, Chapel Hill, NC, 27599-7411, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036456161","display_name":"Hadi Beyhaghi","orcid":"https://orcid.org/0000-0003-2862-9663","observed_orcids":["https://orcid.org/0000-0003-2862-9663"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hadi Beyhaghi","raw_affiliation_strings":["Department of Health Policy and Management, The University of North Carolina at Chapel Hill, 1105A McGavran-Greenberg Hall, CB #7411, Chapel Hill, NC, 27599-7411, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Policy and Management, The University of North Carolina at Chapel Hill, 1105A McGavran-Greenberg Hall, CB #7411, Chapel Hill, NC, 27599-7411, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015424557","display_name":"Josh Sommer","orcid":"https://orcid.org/0000-0001-6780-1871","observed_orcids":["https://orcid.org/0000-0001-6780-1871"]},"institutions":[{"id":"https://openalex.org/I4210106812","display_name":"Chordoma Foundation","ror":"https://ror.org/01vpcr438","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210106812"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Josh Sommer","raw_affiliation_strings":["Chordoma Foundation, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chordoma Foundation, Durham, NC, USA","institution_ids":["https://openalex.org/I4210106812"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045265283","display_name":"Antonia Vickery Bennett","orcid":"https://orcid.org/0000-0002-8968-4511","observed_orcids":["https://orcid.org/0000-0002-8968-4511"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Antonia V. Bennett","raw_affiliation_strings":["Department of Health Policy and Management, The University of North Carolina at Chapel Hill, 1105A McGavran-Greenberg Hall, CB #7411, Chapel Hill, NC, 27599-7411, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Policy and Management, The University of North Carolina at Chapel Hill, 1105A McGavran-Greenberg Hall, CB #7411, Chapel Hill, NC, 27599-7411, USA","institution_ids":["https://openalex.org/I114027177"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5031766760"],"corresponding_institution_ids":["https://openalex.org/I114027177"],"apc_list":{"value":3890,"currency":"USD","value_usd":3890},"apc_paid":{"value":3890,"currency":"USD","value_usd":3890},"fwci":0.7089,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.68667121,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"26","issue":"8","first_page":"2237","last_page":"2244"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":0.9375,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":0.9375,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.05770000070333481,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11669","display_name":"Head and Neck Surgical Oncology","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chordoma","display_name":"chordoma","score":1.0},{"id":"https://openalex.org/keywords/symptom-burden","display_name":"symptom burden","score":0.9750000238418579},{"id":"https://openalex.org/keywords/caregivers","display_name":"caregivers","score":0.6639999747276306},{"id":"https://openalex.org/keywords/life-problems","display_name":"life problems","score":0.8159999847412109},{"id":"https://openalex.org/keywords/chronic-pain","display_name":"chronic pain","score":0.968999981880188},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.8560000061988831},{"id":"https://openalex.org/keywords/anxiety","display_name":"anxiety","score":0.9769999980926514},{"id":"https://openalex.org/keywords/chronic-fatigue","display_name":"chronic fatigue","score":0.9789999723434448},{"id":"https://openalex.org/keywords/delayed-diagnosis","display_name":"delayed diagnosis","score":0.9520000219345093},{"id":"https://openalex.org/keywords/long-term-disability","display_name":"long-term disability","score":0.9660000205039978},{"id":"https://openalex.org/keywords/grief","display_name":"grief","score":0.765999972820282},{"id":"https://openalex.org/keywords/patient-reported-outcomes","display_name":"patient-reported outcomes","score":0.8650000095367432},{"id":"https://openalex.org/keywords/skull-base-tumors","display_name":"skull base tumors","score":0.6159999966621399},{"id":"https://openalex.org/keywords/online-patient-communities","display_name":"online patient communities","score":0.7179999947547913}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7645838260650635},{"id":"https://openalex.org/C2781190729","wikidata":"https://www.wikidata.org/wiki/Q1076389","display_name":"Chordoma","level":2,"score":0.6425612568855286},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.5839616656303406},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.5441376566886902},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.49190211296081543},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4374268651008606},{"id":"https://openalex.org/C142052008","wikidata":"https://www.wikidata.org/wiki/Q954027","display_name":"Cross-sectional study","level":2,"score":0.4257064163684845},{"id":"https://openalex.org/C2994186709","wikidata":"https://www.wikidata.org/wiki/Q29483","display_name":"Palliative care","level":2,"score":0.4250299334526062},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.23122766613960266},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17067450284957886},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.15414705872535706},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.11485752463340759},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.09227541089057922},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002817","descriptor_name":"Chordoma","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D017028","descriptor_name":"Caregivers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1007/s11136-017-1544-2","doi":"https://doi.org/10.1007/s11136-017-1544-2","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11136-017-1544-2","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11136-017-1544-2.pdf","source":{"id":"https://openalex.org/S90347677","display_name":"Quality of Life Research","issn_l":"0962-9343","issn":["0962-9343","1573-2649"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["abdc-a","anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","fnege-3","jufo-3","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Quality of Life Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4371974","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5509836","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5509836","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5509836","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Qual Life Res","raw_type":"Text"},{"id":"pmid:28315176","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28315176","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation","raw_type":"Journal Article"},{"id":"pmh:cdr.lib.unc.edu:sn00b3640","doi":null,"is_oa":true,"landing_page_url":"https://doi.org/10.17615/yasf-2b54","pdf_url":"https://cdr.lib.unc.edu/downloads/ks65hj371","source":{"id":"https://openalex.org/S4306401075","display_name":"Carolina Digital Repository (University of North Carolina at Chapel Hill)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114027177","host_organization_name":"University of North Carolina at Chapel Hill","host_organization_lineage":["https://openalex.org/I114027177"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Quality of Life Research, 26(8)","raw_type":"Article"},{"id":"doi:10.17615/yasf-2b54","doi":"https://doi.org/10.17615/yasf-2b54","is_oa":true,"landing_page_url":"https://doi.org/10.17615/yasf-2b54","pdf_url":null,"source":{"id":"https://openalex.org/S7407051488","display_name":"UNC Libraries","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1007/s11136-017-1544-2","doi":"https://doi.org/10.1007/s11136-017-1544-2","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11136-017-1544-2","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11136-017-1544-2.pdf","source":{"id":"https://openalex.org/S90347677","display_name":"Quality of Life Research","issn_l":"0962-9343","issn":["0962-9343","1573-2649"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["abdc-a","anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","fnege-3","jufo-3","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Quality of Life Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2597072370.pdf","grobid_xml":"https://content.openalex.org/works/W2597072370.grobid-xml"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W1533601335","https://openalex.org/W1548384229","https://openalex.org/W1563804318","https://openalex.org/W2042390728","https://openalex.org/W2082064668","https://openalex.org/W2101184089","https://openalex.org/W2102036561","https://openalex.org/W2109736176","https://openalex.org/W2120155459","https://openalex.org/W2128123119","https://openalex.org/W2160120716","https://openalex.org/W2339162560","https://openalex.org/W2554812284","https://openalex.org/W4243562514"],"related_works":["https://openalex.org/W4396642998","https://openalex.org/W4323922478","https://openalex.org/W4388589534","https://openalex.org/W4367320577","https://openalex.org/W4407735426","https://openalex.org/W1533601335","https://openalex.org/W2080094946","https://openalex.org/W2590519983","https://openalex.org/W4416139986","https://openalex.org/W4389346309"],"abstract_inverted_index":{"PURPOSE:":[0],"This":[1,206],"study":[2,190,207],"aims":[3],"to":[4,43,61,163],"characterize":[5],"the":[6,28,45,54,78,94,117,127,145,176,213,227],"symptom":[7,131,195],"burden":[8,196],"and":[9,15,39,50,73,87,109,139,156,173,197,203,222,236],"life":[10,51,198],"challenges":[11,52,148,199,223],"that":[12,224],"chordoma":[13,85,201,241],"patients":[14,86,95,202],"their":[16,204],"caregivers":[17],"experience.":[18],"METHODS:":[19],"In":[20],"this":[21],"cross-sectional":[22],"study,":[23],"we":[24],"analyzed":[25],"data":[26],"from":[27,110],"Chordoma":[29],"Foundation":[30],"online":[31],"community":[32],"survey":[33,79],"conducted":[34],"in":[35,53,158,232],"2014.":[36],"Frequency":[37],"counts":[38],"percentages":[40],"were":[41,96,185],"calculated":[42],"determine":[44],"prevalence":[46,214],"of":[47,93,212,215,219,229],"self-reported":[48,63,220],"symptoms":[49,64,221],"sample.":[55],"We":[56],"used":[57],"Fisher's":[58],"exact":[59],"test":[60],"compare":[62],"among":[65,200],"subgroups":[66],"with":[67,179],"different":[68],"disease":[69,183],"status,":[70],"tumor":[71,120],"locations,":[72],"treatments":[74],"received.":[75],"RESULTS:":[76],"Among":[77,143],"participants,":[80],"358":[81],"identified":[82],"themselves":[83],"as":[84,89],"208":[88],"caregivers.":[90,205],"The":[91],"majority":[92],"over":[97],"45":[98],"years":[99],"(72%),":[100],"male":[101],"(56%),":[102],"educated":[103],"beyond":[104],"high":[105,194],"school":[106],"degree":[107],"(87%),":[108],"North":[111],"America":[112],"(77%).":[113],"Skull":[114],"base":[115],"was":[116,126],"most":[118,128,146,186],"prevalent":[119],"location":[121],"(40%).":[122],"Chronic":[123],"pain":[124],"(38%)":[125],"commonly":[129],"reported":[130],"followed":[132],"by":[133],"depression":[134],"or":[135,160,181],"severe":[136],"anxiety":[137],"(35%),":[138],"chronic":[140],"fatigue":[141],"(34%).":[142],"patients,":[144],"commonly-reported":[147],"included":[149],"delayed":[150,170],"diagnosis":[151,171],"(37%),":[152],"long-term":[153],"disability":[154],"(33%),":[155],"change":[157],"career":[159],"reduced":[161],"ability":[162],"work":[164],"(33%).":[165],"For":[166],"caregivers,":[167],"grief":[168],"(55%),":[169],"(47%),":[172],"difficulty":[174],"helping":[175],"patient":[177],"cope":[178],"his":[180],"her":[182],"(45%)":[184],"common.":[187],"CONCLUSIONS:":[188],"Our":[189],"findings":[191],"suggest":[192],"a":[193,216],"provides":[208],"preliminary,":[209],"limited":[210],"estimates":[211],"wide":[217],"range":[218],"will":[225],"inform":[226],"assessment":[228],"patient-reported":[230],"outcomes":[231],"future":[233],"clinical":[234],"trials":[235],"help":[237],"clinicians":[238],"better":[239],"manage":[240],"patients'":[242],"symptoms.":[243]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-03-23T00:00:00"}