{"id":"https://openalex.org/W2596611191","doi":"https://doi.org/10.1200/jco.2012.30.15_suppl.6537","title":"Low day 100 transplant-related mortality (TRM) and relapse rate following clofarabine (CLO) in combination with cytarabine, total body irradiation (TBI), and allogeneic stem cell transplantation (AlloSCT) in children, adolescents, and young adults (CAYA) with poor-risk acute leukemia.","display_name":"Low day 100 transplant-related mortality (TRM) and relapse rate following clofarabine (CLO) in combination with cytarabine, total body irradiation (TBI), and allogeneic stem cell transplantation (AlloSCT) in children, adolescents, and young adults (CAYA) with poor-risk acute leukemia.","publication_year":2012,"publication_date":"2012-05-20","ids":{"openalex":"https://openalex.org/W2596611191","doi":"https://doi.org/10.1200/jco.2012.30.15_suppl.6537","mag":"2596611191"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2012.30.15_suppl.6537","doi":"https://doi.org/10.1200/jco.2012.30.15_suppl.6537","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2012.30.15_suppl.6537","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Kavita Radhakrishnan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181190671","display_name":"New York Medical College","ror":"https://ror.org/03dkvy735","country_code":"US","type":"education","lineage":["https://openalex.org/I181190671"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kavita Radhakrishnan","raw_affiliation_strings":["New York Medical College, Valhalla, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York Medical College, Valhalla, NY","institution_ids":["https://openalex.org/I181190671"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072040073","display_name":"Angela M. Ricci","orcid":"https://orcid.org/0000-0003-3507-9946","observed_orcids":["https://orcid.org/0000-0003-3507-9946"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Angela M Ricci","raw_affiliation_strings":["Columbia University, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University, New York, NY","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040703931","display_name":"Mark Blaine Geyer","orcid":"https://orcid.org/0000-0001-5248-9117","observed_orcids":["https://orcid.org/0000-0001-5248-9117"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark B Geyer","raw_affiliation_strings":["Massachusetts General Hospital, Harvard University, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts General Hospital, Harvard University, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023129428","display_name":"Lauren Harrison","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181190671","display_name":"New York Medical College","ror":"https://ror.org/03dkvy735","country_code":"US","type":"education","lineage":["https://openalex.org/I181190671"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lauren Harrison","raw_affiliation_strings":["New York Medical College, Valhalla, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York Medical College, Valhalla, NY","institution_ids":["https://openalex.org/I181190671"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112056285","display_name":"Deirdre Duffy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181190671","display_name":"New York Medical College","ror":"https://ror.org/03dkvy735","country_code":"US","type":"education","lineage":["https://openalex.org/I181190671"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deirdre Duffy","raw_affiliation_strings":["New York Medical College, Valhalla, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York Medical College, Valhalla, NY","institution_ids":["https://openalex.org/I181190671"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109358261","display_name":"Mehmet Fevzi Ozkaynak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181190671","display_name":"New York Medical College","ror":"https://ror.org/03dkvy735","country_code":"US","type":"education","lineage":["https://openalex.org/I181190671"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mehmet Fevzi Ozkaynak","raw_affiliation_strings":["New York Medical College, Valhalla, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York Medical College, Valhalla, NY","institution_ids":["https://openalex.org/I181190671"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048733835","display_name":"Prakash Satwani","orcid":"https://orcid.org/0000-0003-3867-9066","observed_orcids":["https://orcid.org/0000-0003-3867-9066"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Prakash Satwani","raw_affiliation_strings":["Columbia University, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University, New York, NY","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017037465","display_name":"Alexandra C. Cheerva","orcid":"https://orcid.org/0000-0002-6494-1817","observed_orcids":["https://orcid.org/0000-0002-6494-1817"]},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexandra C Cheerva","raw_affiliation_strings":["University of Louisville, Louisville, KY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Louisville, Louisville, KY","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087456665","display_name":"Julie\u2010An Talano","orcid":"https://orcid.org/0000-0003-2645-0854","observed_orcids":["https://orcid.org/0000-0003-2645-0854"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julie Talano","raw_affiliation_strings":["Medical College of Wisconsin, Milwaukee, WI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical College of Wisconsin, Milwaukee, WI","institution_ids":["https://openalex.org/I204308271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054509454","display_name":"Theodore Bruce Moore","orcid":"https://orcid.org/0000-0002-7909-610X","observed_orcids":["https://orcid.org/0000-0002-7909-610X"]},"institutions":[{"id":"https://openalex.org/I2801272649","display_name":"Ronald Reagan UCLA Medical Center","ror":"https://ror.org/04k3jt835","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799798094","https://openalex.org/I2801272649"]},{"id":"https://openalex.org/I2801403999","display_name":"UCLA Medical Center","ror":"https://ror.org/04vq5kb54","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799798094","https://openalex.org/I2801403999"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Theodore Moore","raw_affiliation_strings":["UCLA Medical Center, Los Angeles, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCLA Medical Center, Los Angeles, CA","institution_ids":["https://openalex.org/I2801272649","https://openalex.org/I2801403999"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027095419","display_name":"Alfred P. Gillio","orcid":"https://orcid.org/0000-0001-8391-3101","observed_orcids":["https://orcid.org/0000-0001-8391-3101"]},"institutions":[{"id":"https://openalex.org/I1324520350","display_name":"Hackensack University Medical Center","ror":"https://ror.org/008zj0x80","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1324520350"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alfred P Gillio","raw_affiliation_strings":["Hackensack University Medical Center, Hackensack, NJ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hackensack University Medical Center, Hackensack, NJ","institution_ids":["https://openalex.org/I1324520350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021012824","display_name":"Randal K. Wada","orcid":"https://orcid.org/0000-0002-6563-6160","observed_orcids":["https://orcid.org/0000-0002-6563-6160"]},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]},{"id":"https://openalex.org/I1331384533","display_name":"University of Hawaii System","ror":"https://ror.org/03tzaeb71","country_code":"US","type":"education","lineage":["https://openalex.org/I1331384533"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Randal K. Wada","raw_affiliation_strings":["University of Hawaii, Honolulu, HI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Hawaii, Honolulu, HI","institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080362489","display_name":"Lee Ann Baxter\u2010Lowe","orcid":"https://orcid.org/0000-0002-6706-0273","observed_orcids":["https://orcid.org/0000-0002-6706-0273"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lee Ann Baxter-Lowe","raw_affiliation_strings":["University of California, San Francisco, San Francisco, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, San Francisco, CA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001697191","display_name":"Mitchell Stuart Cairo","orcid":"https://orcid.org/0000-0002-2075-434X","observed_orcids":["https://orcid.org/0000-0002-2075-434X"]},"institutions":[{"id":"https://openalex.org/I181190671","display_name":"New York Medical College","ror":"https://ror.org/03dkvy735","country_code":"US","type":"education","lineage":["https://openalex.org/I181190671"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mitchell S. Cairo","raw_affiliation_strings":["New York Medical College, Valhalla, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York Medical College, Valhalla, NY","institution_ids":["https://openalex.org/I181190671"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":12,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"30","issue":"15_suppl","first_page":"6537","last_page":"6537"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.8363999724388123,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.8363999724388123,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.11760000139474869,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.015200000256299973,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/clofarabine","display_name":"clofarabine","score":0.996999979019165},{"id":"https://openalex.org/keywords/cytarabine","display_name":"cytarabine","score":0.9760000109672546},{"id":"https://openalex.org/keywords/total-body-irradiation","display_name":"total body irradiation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/allogeneic-stem-cell-transplantation","display_name":"allogeneic stem cell transplantation","score":0.9789999723434448},{"id":"https://openalex.org/keywords/conditioning-regimen","display_name":"conditioning regimen","score":0.7210000157356262},{"id":"https://openalex.org/keywords/relapsed-acute-lymphoblastic-leukemia","display_name":"relapsed acute lymphoblastic leukemia","score":0.8450000286102295},{"id":"https://openalex.org/keywords/relapsed-acute-myeloid-leukemia","display_name":"relapsed acute myeloid leukemia","score":0.9070000052452087},{"id":"https://openalex.org/keywords/failed-induction","display_name":"induction failure","score":0.6629999876022339},{"id":"https://openalex.org/keywords/treatment-related-mortality","display_name":"non-relapse mortality","score":0.6919999718666077},{"id":"https://openalex.org/keywords/relapse-rate","display_name":"relapse rate","score":0.7749999761581421},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.8519999980926514},{"id":"https://openalex.org/keywords/engraftment","display_name":"engraftment","score":0.7609999775886536},{"id":"https://openalex.org/keywords/graft-versus-host-disease","display_name":"graft-versus-host disease","score":0.9350000023841858},{"id":"https://openalex.org/keywords/unrelated-donor-transplantation","display_name":"unrelated donor transplantation","score":0.44200000166893005}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8374201059341431},{"id":"https://openalex.org/C2777198975","wikidata":"https://www.wikidata.org/wiki/Q5134875","display_name":"Clofarabine","level":4,"score":0.6849258542060852},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6455785036087036},{"id":"https://openalex.org/C2778041864","wikidata":"https://www.wikidata.org/wiki/Q180983","display_name":"Cytarabine","level":3,"score":0.6227123141288757},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5737672448158264},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.5202801823616028},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.512577474117279},{"id":"https://openalex.org/C2778880498","wikidata":"https://www.wikidata.org/wiki/Q1986672","display_name":"Total body irradiation","level":4,"score":0.4503372013568878},{"id":"https://openalex.org/C142424586","wikidata":"https://www.wikidata.org/wiki/Q7307572","display_name":"Refractory (planetary science)","level":2,"score":0.41414064168930054},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3973532021045685},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.2515299320220947},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.2056136429309845},{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.16063883900642395},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C87355193","wikidata":"https://www.wikidata.org/wiki/Q411","display_name":"Astrobiology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1200/jco.2012.30.15_suppl.6537","doi":"https://doi.org/10.1200/jco.2012.30.15_suppl.6537","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2012.30.15_suppl.6537","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4250964946","https://openalex.org/W2142426848","https://openalex.org/W2026507020","https://openalex.org/W2167635628","https://openalex.org/W2808276676","https://openalex.org/W2979935428","https://openalex.org/W86292568","https://openalex.org/W2507380486","https://openalex.org/W2031450750","https://openalex.org/W2578847309"],"abstract_inverted_index":{"6537":[0],"Background:":[1],"CAYA":[2,44,79,130,279],"with":[3,45,53,70,80,131,139,280,284,292,305],"ALL":[4],"or":[5,15,126,136],"AML":[6,283],"in":[7,43,78,129,133,278,309],"third":[8],"complete":[9],"remission":[10],"(CR3),":[11],"refractory":[12],"relapse":[13,303],"(RR)":[14],"induction":[16],"failure":[17],"(IF)":[18],"have":[19],"an":[20,32],"extremely":[21],"poor":[22],"prognosis,":[23],"<20%":[24],"EFS":[25],"(Gaynon,":[26],"BJH,":[27],"2005;Wells,":[28],"JCO,":[29],"2003).":[30],"CLO,":[31,71],"inhibitor":[33],"of":[34,91,96,147,162,215,241,249,297],"DNA":[35],"polymerase":[36],"and":[37,51,65,73,117,149,166,198,203,207,209,219,226,252,258,275,301],"ribonucleotide":[38],"reductase,":[39],"has":[40],"significant":[41],"activity":[42],"relapsed":[46],"ALL/AML":[47,132],"(Jeha,":[48],"JCO":[49],"2006,2009)":[50],"synergy":[52],"cytarabine":[54,72,113],"(Faderl,":[55],"Blood,":[56],"2005).":[57],"We":[58],"sought":[59],"to":[60,158,294],"determine":[61,159],"safety,":[62],"day-100":[63],"TRM,":[64],"overall":[66],"survival":[67],"(OS)":[68],"associated":[69,304],"TBI":[74,118],"followed":[75,120,270],"by":[76,121,271],"AlloSCT":[77,122,272],"poor-risk":[81,281,311],"ALL/AML.":[82],"Methods:":[83],"This":[84],"is":[85,273],"a":[86,92],"multi-center":[87],"phase":[88],"I/II":[89],"trial":[90],"novel":[93,268],"conditioning":[94,307],"regimen":[95,269,308],"CLO":[97,229,285],"(dose":[98],"escalation:":[99],"40mg/m2":[100],"[n=3],":[101,104],"46":[102],"mg/m2":[103,106,115],"52":[105,287],"[n=19])":[107],"x5d,":[108],"sequential":[109],"(4":[110],"hrs":[111],"later)":[112],"1000":[114],"x6d":[116],"(1200cGy)":[119],"from":[123],"matched":[124],"related":[125,187],"unrelated":[127,140,190],"donors":[128,141,191],"CR3,":[134,181],"RR":[135],"IF.":[137],"Patients":[138],"received":[142],"R-ATG.":[143],"GVHD":[144],"prophylaxis":[145],"consisted":[146],"tacrolimus":[148],"MMF":[150],"(Bhatia/Cairo,":[151],"BBMT,":[152],"2009).":[153],"Kaplan-Meier":[154],"method":[155],"was":[156,201,231,245],"used":[157],"the":[160],"probabilities":[161],"engraftment,":[163],"GVHD,":[164],"TRM":[165,244,300],"OS.":[167],"Results:":[168],"25":[169],"pts,":[170],"median":[171],"age:":[172],"11.3":[173],"yrs":[174],"(1.5-20.7);":[175],"M:F:":[176],"19:6,":[177],"ALL/AML:":[178],"22:3":[179],"(10":[180],"3":[182],"RR,":[183],"12":[184],"IF),":[185],"10":[186],"donors,":[188],"15":[189],"(9":[192],"BM/PBSCs,":[193],"6":[194],"UCB).":[195],"Median":[196],"TNC":[197],"CD34":[199],"dose":[200,230,237,286],"4.47x108/kg":[202],"4.84x106/kg":[204],"for":[205,211],"BM/PBSCs":[206],"4.0x107/kg":[208],"2.8x105/kg":[210],"UCB,":[212],"respectively.":[213,228,262],"Probabilities":[214],"neutrophil,":[216],"platelet":[217],"engraftment":[218],"grade":[220],"II-IV":[221],"aGVHD":[222],"were":[223,254],"100%,":[224],"92.9%":[225],"47.5%,":[227],"tolerable":[232],"at":[233],"52mg/m2/d":[234],"x5d":[235],"without":[236],"limiting":[238],"toxicity.":[239],"Probability":[240,248],"Day":[242],"100":[243,299],"only":[246],"4.3%.":[247],"1-yr":[250],"PFS":[251],"OS":[253],"51%":[255],"(CI95:":[256,260],"28-71%),":[257],"43%":[259],"22-63%)":[261],"Conclusions:":[263],"Preliminary":[264],"results":[265],"suggest":[266],"this":[267,306,310],"safe":[274],"well":[276],"tolerated":[277],"ALL/":[282],"mg/m2.":[288],"Results":[289],"are":[290],"encouraging":[291],"respect":[293],"low":[295],"risk":[296],"day":[298],"leukemic":[302],"population.":[312]},"counts_by_year":[],"updated_date":"2026-10-02T10:15:12.560889","created_date":"2017-03-23T00:00:00"}