{"id":"https://openalex.org/W2595004244","doi":"https://doi.org/10.1161/circresaha.116.308996","title":"Heart Failure in Pediatric Patients With Congenital Heart Disease","display_name":"Heart Failure in Pediatric Patients With Congenital Heart Disease","publication_year":2017,"publication_date":"2017-03-16","ids":{"openalex":"https://openalex.org/W2595004244","doi":"https://doi.org/10.1161/circresaha.116.308996","mag":"2595004244","pmid":"https://pubmed.ncbi.nlm.nih.gov/28302743","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5391045"},"language":"en","primary_location":{"id":"doi:10.1161/circresaha.116.308996","doi":"https://doi.org/10.1161/circresaha.116.308996","is_oa":true,"landing_page_url":"https://doi.org/10.1161/circresaha.116.308996","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/CIRCRESAHA.116.308996","source":{"id":"https://openalex.org/S10652568","display_name":"Circulation Research","issn_l":"0009-7330","issn":["0009-7330","1524-4571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Research","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.ahajournals.org/doi/pdf/10.1161/CIRCRESAHA.116.308996","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087438813","display_name":"Robert B. Hinton","orcid":"https://orcid.org/0000-0002-7771-9510","observed_orcids":["https://orcid.org/0000-0002-7771-9510"]},"institutions":[{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]},{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert B. Hinton","raw_affiliation_strings":["From the Department of Pediatrics and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis","Robert B. Hinton From the Department of Pediatrics and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Pediatrics and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]},{"raw_affiliation_string":"Robert B. Hinton From the Department of Pediatrics and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130","https://openalex.org/I55769427"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020642145","display_name":"Stephanie M. Ware","orcid":"https://orcid.org/0000-0003-4714-0142","observed_orcids":["https://orcid.org/0000-0003-4714-0142"]},"institutions":[{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]},{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephanie M. Ware","raw_affiliation_strings":["From the Department of Pediatrics and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis","Stephanie M. Ware From the Department of Pediatrics and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Pediatrics and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]},{"raw_affiliation_string":"Stephanie M. Ware From the Department of Pediatrics and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130","https://openalex.org/I55769427"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.2123,"has_fulltext":true,"cited_by_count":217,"citation_normalized_percentile":{"value":0.91564383,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"120","issue":"6","first_page":"978","last_page":"994"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10300","display_name":"Congenital Heart Disease Studies","score":0.6064000129699707,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10300","display_name":"Congenital Heart Disease Studies","score":0.6064000129699707,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.0940999984741211,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.06759999692440033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.871999979019165},{"id":"https://openalex.org/keywords/pediatric-heart-failure","display_name":"pediatric heart failure","score":0.8550000190734863},{"id":"https://openalex.org/keywords/congenital-heart-disease","display_name":"congenital heart disease","score":1.0},{"id":"https://openalex.org/keywords/phenotyping","display_name":"phenotyping","score":0.6010000109672546},{"id":"https://openalex.org/keywords/genome","display_name":"genome","score":0.5099999904632568},{"id":"https://openalex.org/keywords/transcriptome","display_name":"transcriptome","score":1.0},{"id":"https://openalex.org/keywords/epigenetics","display_name":"epigenetics","score":0.9950000047683716},{"id":"https://openalex.org/keywords/heart-failure-epidemiology","display_name":"heart failure epidemiology","score":0.671999990940094}],"concepts":[{"id":"https://openalex.org/C2780074459","wikidata":"https://www.wikidata.org/wiki/Q389735","display_name":"Heart disease","level":2,"score":0.7534044981002808},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.6988154053688049},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6612932085990906},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6137501001358032},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6044828295707703},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.49720242619514465},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4663136899471283},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.4188942313194275},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.35233259201049805},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27662336826324463},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1088254451751709},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006330","descriptor_name":"Heart Defects, Congenital","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006330","descriptor_name":"Heart Defects, Congenital","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018754","descriptor_name":"Ventricular Dysfunction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1161/circresaha.116.308996","doi":"https://doi.org/10.1161/circresaha.116.308996","is_oa":true,"landing_page_url":"https://doi.org/10.1161/circresaha.116.308996","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/CIRCRESAHA.116.308996","source":{"id":"https://openalex.org/S10652568","display_name":"Circulation Research","issn_l":"0009-7330","issn":["0009-7330","1524-4571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Research","raw_type":"journal-article"},{"id":"pmid:28302743","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28302743","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation research","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:4757314","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5391045","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5391045","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5391045/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Circ Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1161/circresaha.116.308996","doi":"https://doi.org/10.1161/circresaha.116.308996","is_oa":true,"landing_page_url":"https://doi.org/10.1161/circresaha.116.308996","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/CIRCRESAHA.116.308996","source":{"id":"https://openalex.org/S10652568","display_name":"Circulation Research","issn_l":"0009-7330","issn":["0009-7330","1524-4571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6715630927","display_name":"Role of the Embryonic Node in Cardiac Development and Congenital Heart Disease","funder_award_id":"R01HL088639","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6849427863","display_name":"Genotype-Phenotype Associations in Pediatric Cardiomyopathy","funder_award_id":"R01HL111459","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000916565","display_name":"Morphogenesis and growth of the ventricular wall in development and disease","funder_award_id":"P01HL134599","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320306182","display_name":"March of Dimes Foundation","ror":"https://ror.org/04bd5p711"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2595004244.pdf","grobid_xml":"https://content.openalex.org/works/W2595004244.grobid-xml"},"referenced_works_count":152,"referenced_works":["https://openalex.org/W92742077","https://openalex.org/W177499201","https://openalex.org/W585639130","https://openalex.org/W852063183","https://openalex.org/W1109775121","https://openalex.org/W1488372279","https://openalex.org/W1501608538","https://openalex.org/W1506409704","https://openalex.org/W1589533958","https://openalex.org/W1737257901","https://openalex.org/W1891872093","https://openalex.org/W1891888420","https://openalex.org/W1893246933","https://openalex.org/W1917974736","https://openalex.org/W1933967300","https://openalex.org/W1966637859","https://openalex.org/W1968705313","https://openalex.org/W1976646890","https://openalex.org/W1976888408","https://openalex.org/W1979742883","https://openalex.org/W1981683677","https://openalex.org/W1983569018","https://openalex.org/W1983802385","https://openalex.org/W1987050564","https://openalex.org/W1987399272","https://openalex.org/W1987843933","https://openalex.org/W1989891963","https://openalex.org/W1994663942","https://openalex.org/W2000548479","https://openalex.org/W2001102891","https://openalex.org/W2005171546","https://openalex.org/W2009667615","https://openalex.org/W2010699851","https://openalex.org/W2010853153","https://openalex.org/W2012517517","https://openalex.org/W2012581363","https://openalex.org/W2014022579","https://openalex.org/W2014942570","https://openalex.org/W2015026613","https://openalex.org/W2016786206","https://openalex.org/W2016864623","https://openalex.org/W2017923546","https://openalex.org/W2024197223","https://openalex.org/W2024501954","https://openalex.org/W2025349319","https://openalex.org/W2028761750","https://openalex.org/W2029422437","https://openalex.org/W2032476617","https://openalex.org/W2035847235","https://openalex.org/W2036299862","https://openalex.org/W2036532359","https://openalex.org/W2036645638","https://openalex.org/W2038368430","https://openalex.org/W2038903080","https://openalex.org/W2039420108","https://openalex.org/W2039820053","https://openalex.org/W2042108111","https://openalex.org/W2044616793","https://openalex.org/W2046092155","https://openalex.org/W2048536272","https://openalex.org/W2049558210","https://openalex.org/W2049671475","https://openalex.org/W2050144809","https://openalex.org/W2051005896","https://openalex.org/W2051694207","https://openalex.org/W2052833946","https://openalex.org/W2053146170","https://openalex.org/W2058446860","https://openalex.org/W2060687299","https://openalex.org/W2062613290","https://openalex.org/W2065823779","https://openalex.org/W2068109108","https://openalex.org/W2071256604","https://openalex.org/W2071518542","https://openalex.org/W2073254471","https://openalex.org/W2075318595","https://openalex.org/W2082468994","https://openalex.org/W2084213288","https://openalex.org/W2084730656","https://openalex.org/W2088543916","https://openalex.org/W2091023293","https://openalex.org/W2091831410","https://openalex.org/W2092710299","https://openalex.org/W2101215415","https://openalex.org/W2101498722","https://openalex.org/W2102780353","https://openalex.org/W2103579660","https://openalex.org/W2104276565","https://openalex.org/W2106666507","https://openalex.org/W2107696376","https://openalex.org/W2109712401","https://openalex.org/W2110519205","https://openalex.org/W2113133345","https://openalex.org/W2118719488","https://openalex.org/W2119706727","https://openalex.org/W2119707364","https://openalex.org/W2122290210","https://openalex.org/W2122509013","https://openalex.org/W2124301113","https://openalex.org/W2124997477","https://openalex.org/W2125921590","https://openalex.org/W2126250632","https://openalex.org/W2128395485","https://openalex.org/W2131448076","https://openalex.org/W2131463364","https://openalex.org/W2133397439","https://openalex.org/W2134088866","https://openalex.org/W2137854396","https://openalex.org/W2141838743","https://openalex.org/W2144101811","https://openalex.org/W2145306368","https://openalex.org/W2145944075","https://openalex.org/W2145968090","https://openalex.org/W2146107927","https://openalex.org/W2146878987","https://openalex.org/W2147067922","https://openalex.org/W2147192856","https://openalex.org/W2148598424","https://openalex.org/W2149440091","https://openalex.org/W2153819921","https://openalex.org/W2157454779","https://openalex.org/W2159539066","https://openalex.org/W2160093153","https://openalex.org/W2162347038","https://openalex.org/W2167363119","https://openalex.org/W2168048360","https://openalex.org/W2169575327","https://openalex.org/W2170572248","https://openalex.org/W2213651558","https://openalex.org/W2236725967","https://openalex.org/W2238514531","https://openalex.org/W2263904841","https://openalex.org/W2283987082","https://openalex.org/W2295219003","https://openalex.org/W2297972901","https://openalex.org/W2318954867","https://openalex.org/W2332619088","https://openalex.org/W2336271781","https://openalex.org/W2346568680","https://openalex.org/W2378220406","https://openalex.org/W2401074552","https://openalex.org/W2414520056","https://openalex.org/W2469663434","https://openalex.org/W2475049325","https://openalex.org/W2500269539","https://openalex.org/W2507681278","https://openalex.org/W2517885349","https://openalex.org/W2546627019","https://openalex.org/W2946448066","https://openalex.org/W4206632929","https://openalex.org/W4233139525","https://openalex.org/W4244886534"],"related_works":["https://openalex.org/W4400385982","https://openalex.org/W4415300233","https://openalex.org/W2901997601","https://openalex.org/W4399138633","https://openalex.org/W2101818794","https://openalex.org/W2060687299","https://openalex.org/W3011859369","https://openalex.org/W2809837595","https://openalex.org/W7217319051","https://openalex.org/W3087161706"],"abstract_inverted_index":{"Heart":[0],"failure":[1],"(HF)":[2],"is":[3,31,102],"a":[4,105],"complex":[5],"clinical":[6,124],"syndrome":[7],"resulting":[8],"from":[9,60,94],"diverse":[10],"primary":[11],"and":[12,15,26,52,71,81,86,112,125,140,145],"secondary":[13],"causes":[14],"shared":[16],"pathways":[17],"of":[18,48,73,99,119,129],"disease":[19,80,134],"progression,":[20],"correlating":[21],"with":[22,40,77],"substantial":[23],"mortality,":[24],"morbidity,":[25],"cost.":[27],"HF":[28,55,74,130],"in":[29,56,63,75,115,131],"children":[30,57,76],"most":[32],"commonly":[33],"attributable":[34],"to":[35,103],"coexistent":[36],"congenital":[37,78,132],"heart":[38,79,133],"disease,":[39],"different":[41],"risks":[42],"depending":[43],"on":[44],"the":[45,68,83,116,137],"specific":[46],"type":[47],"malformation.":[49],"Current":[50],"management":[51],"therapy":[53],"for":[54,107,147],"are":[58,90,150],"extrapolated":[59],"treatment":[61],"approaches":[62],"adults.":[64],"This":[65],"review":[66,101,123],"discusses":[67],"causes,":[69],"epidemiology,":[70],"manifestations":[72],"presents":[82],"clinical,":[84],"genetic,":[85],"molecular":[87,113],"characteristics":[88],"that":[89],"similar":[91],"or":[92],"distinct":[93],"adult":[95],"HF.":[96],"The":[97],"objective":[98],"this":[100],"provide":[104],"framework":[106],"understanding":[108],"rapidly":[109],"increasing":[110],"genetic":[111],"information":[114],"challenging":[117],"context":[118],"detailed":[120],"phenotyping.":[121],"We":[122],"translational":[126],"research":[127],"studies":[128],"including":[135],"at":[136],"genome,":[138],"transcriptome,":[139],"epigenetic":[141],"levels.":[142],"Unresolved":[143],"issues":[144],"directions":[146],"future":[148],"study":[149],"presented.":[151]},"counts_by_year":[{"year":2026,"cited_by_count":24},{"year":2025,"cited_by_count":37},{"year":2024,"cited_by_count":24},{"year":2023,"cited_by_count":29},{"year":2022,"cited_by_count":22},{"year":2021,"cited_by_count":31},{"year":2020,"cited_by_count":22},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":7}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2017-03-23T00:00:00"}
