{"id":"https://openalex.org/W2594464065","doi":"https://doi.org/10.1016/j.chembiol.2017.02.010","title":"Hedgehog Signaling: From Basic Biology to Cancer Therapy","display_name":"Hedgehog Signaling: From Basic Biology to Cancer Therapy","publication_year":2017,"publication_date":"2017-03-01","ids":{"openalex":"https://openalex.org/W2594464065","doi":"https://doi.org/10.1016/j.chembiol.2017.02.010","mag":"2594464065","pmid":"https://pubmed.ncbi.nlm.nih.gov/28286127","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7442121"},"language":"en","primary_location":{"id":"doi:10.1016/j.chembiol.2017.02.010","doi":"https://doi.org/10.1016/j.chembiol.2017.02.010","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.chembiol.2017.02.010","pdf_url":"http://www.cell.com/article/S2451945617300582/pdf","source":{"id":"https://openalex.org/S4210231961","display_name":"Cell chemical biology","issn_l":"2451-9448","issn":["2451-9448","2451-9456"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Chemical Biology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S2451945617300582/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075174948","display_name":"Fujia Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I4210167311","display_name":"Institute of Zoology","ror":"https://ror.org/05skxkv18","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311"]},{"id":"https://openalex.org/I4391767720","display_name":"State Key Laboratory of Stem Cell and Reproductive Biology","ror":"https://ror.org/00eeef580","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311","https://openalex.org/I4391767720"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fujia Wu","raw_affiliation_strings":["State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China","State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China","University of Chinese Academy of Sciences, Beijing 100049, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210165038","https://openalex.org/I4210167311","https://openalex.org/I4391767720"]},{"raw_affiliation_string":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210167311","https://openalex.org/I4391767720"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100433787","display_name":"Yu Zhang","orcid":"https://orcid.org/0009-0009-0912-5225","observed_orcids":["https://orcid.org/0009-0009-0912-5225"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210167311","display_name":"Institute of Zoology","ror":"https://ror.org/05skxkv18","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311"]},{"id":"https://openalex.org/I4391767720","display_name":"State Key Laboratory of Stem Cell and Reproductive Biology","ror":"https://ror.org/00eeef580","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311","https://openalex.org/I4391767720"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Zhang","raw_affiliation_strings":["State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210167311","https://openalex.org/I4391767720"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034619816","display_name":"Bo Sun","orcid":"https://orcid.org/0000-0002-1932-2267","observed_orcids":["https://orcid.org/0000-0002-1932-2267"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210167311","display_name":"Institute of Zoology","ror":"https://ror.org/05skxkv18","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311"]},{"id":"https://openalex.org/I4391767720","display_name":"State Key Laboratory of Stem Cell and Reproductive Biology","ror":"https://ror.org/00eeef580","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311","https://openalex.org/I4391767720"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bo Sun","raw_affiliation_strings":["State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210167311","https://openalex.org/I4391767720"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003394161","display_name":"Andrew P. McMahon","orcid":"https://orcid.org/0000-0002-3779-1729","observed_orcids":["https://orcid.org/0000-0002-3779-1729"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew P. McMahon","raw_affiliation_strings":["Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, W.M. Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, W.M. Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100445227","display_name":"Yu Wang","orcid":"https://orcid.org/0000-0002-5188-4622","observed_orcids":["https://orcid.org/0000-0002-5188-4622"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I4210167311","display_name":"Institute of Zoology","ror":"https://ror.org/05skxkv18","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311"]},{"id":"https://openalex.org/I4391767720","display_name":"State Key Laboratory of Stem Cell and Reproductive Biology","ror":"https://ror.org/00eeef580","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311","https://openalex.org/I4391767720"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yu Wang","raw_affiliation_strings":["State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: wangyu@ioz.ac.cn","State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China","University of Chinese Academy of Sciences, Beijing 100049, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: wangyu@ioz.ac.cn","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210165038","https://openalex.org/I4210167311","https://openalex.org/I4391767720"]},{"raw_affiliation_string":"State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210167311","https://openalex.org/I4391767720"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100445227"],"corresponding_institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210165038","https://openalex.org/I4210167311","https://openalex.org/I4391767720"],"apc_list":{"value":9350,"currency":"USD","value_usd":9350},"apc_paid":null,"fwci":3.5441,"has_fulltext":false,"cited_by_count":305,"citation_normalized_percentile":{"value":0.95667794,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"24","issue":"3","first_page":"252","last_page":"280"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12009","display_name":"Hedgehog Signaling Pathway Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12009","display_name":"Hedgehog Signaling Pathway Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12065","display_name":"Hippo pathway signaling and YAP/TAZ","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hedgehog-signaling","display_name":"Hedgehog signaling","score":0.9440000057220459},{"id":"https://openalex.org/keywords/cancer-therapy","display_name":"cancer therapy","score":0.8740000128746033},{"id":"https://openalex.org/keywords/hedgehog-pathway-inhibitors","display_name":"Hedgehog pathway inhibitors","score":0.6570000052452087},{"id":"https://openalex.org/keywords/embryonic-patterning","display_name":"embryonic patterning","score":0.7850000262260437},{"id":"https://openalex.org/keywords/developmental-biology","display_name":"developmental biology","score":0.7269999980926514},{"id":"https://openalex.org/keywords/small-molecule-modulators","display_name":"small molecule modulators","score":0.7369999885559082},{"id":"https://openalex.org/keywords/drug-development-challenges","display_name":"drug development challenges","score":0.5239999890327454}],"concepts":[{"id":"https://openalex.org/C2778539099","wikidata":"https://www.wikidata.org/wiki/Q6120","display_name":"Hedgehog","level":3,"score":0.7575911283493042},{"id":"https://openalex.org/C88498014","wikidata":"https://www.wikidata.org/wiki/Q14859918","display_name":"Hedgehog signaling pathway","level":3,"score":0.6222665309906006},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5131345391273499},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5047839879989624},{"id":"https://openalex.org/C3018449070","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signalling pathways","level":3,"score":0.4995453357696533},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.4923511743545532},{"id":"https://openalex.org/C2983331546","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer therapy","level":3,"score":0.4230031371116638},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3982521593570709},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3782222270965576},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3487963378429413},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.32875776290893555},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.19226032495498657},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1456916630268097}],"mesh":[{"descriptor_ui":"D000072086","descriptor_name":"Smoothened Receptor","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D000072086","descriptor_name":"Smoothened Receptor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000072086","descriptor_name":"Smoothened Receptor","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D000072376","descriptor_name":"Oxysterols","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000072376","descriptor_name":"Oxysterols","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002923","descriptor_name":"Cilia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018129","descriptor_name":"Phosphatidylinositol Phosphates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018129","descriptor_name":"Phosphatidylinositol Phosphates","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D051741","descriptor_name":"Kruppel-Like Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D053823","descriptor_name":"Hedgehog Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D053823","descriptor_name":"Hedgehog Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D053823","descriptor_name":"Hedgehog Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D054852","descriptor_name":"Small Molecule Libraries","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D054852","descriptor_name":"Small Molecule Libraries","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D054852","descriptor_name":"Small Molecule Libraries","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.chembiol.2017.02.010","doi":"https://doi.org/10.1016/j.chembiol.2017.02.010","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.chembiol.2017.02.010","pdf_url":"http://www.cell.com/article/S2451945617300582/pdf","source":{"id":"https://openalex.org/S4210231961","display_name":"Cell chemical biology","issn_l":"2451-9448","issn":["2451-9448","2451-9456"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Chemical Biology","raw_type":"journal-article"},{"id":"pmid:28286127","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28286127","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell chemical biology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7442121","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7442121","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cell Chem Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.chembiol.2017.02.010","doi":"https://doi.org/10.1016/j.chembiol.2017.02.010","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.chembiol.2017.02.010","pdf_url":"http://www.cell.com/article/S2451945617300582/pdf","source":{"id":"https://openalex.org/S4210231961","display_name":"Cell chemical biology","issn_l":"2451-9448","issn":["2451-9448","2451-9456"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Chemical Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1676666550","display_name":null,"funder_award_id":"2014CB964900","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G1903033493","display_name":"Regulation of polarity by Sonic hedgehog morphogen signaling","funder_award_id":"R01NS033642","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G563050417","display_name":null,"funder_award_id":"2015CB964800","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G7867750073","display_name":"Regulation of CNS and Limb Polarity by Sonic Hedgehog","funder_award_id":"R37NS033642","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G8539878022","display_name":"\u9762\u5411Hedgehog\u4fe1\u53f7\u901a\u8def\u4e2dGli\u8f6c\u5f55\u56e0\u5b50\u7684\u5c0f\u5206\u5b50\u7b5b\u9009\u548c\u8c03\u63a7\u673a\u5236\u7814\u7a76","funder_award_id":"31571514","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G9000256801","display_name":null,"funder_award_id":"NS-033642","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F3346020281","display_name":"State Key Laboratory of Stem Cell and Reproductive Biology","ror":"https://ror.org/00eeef580"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2594464065.pdf"},"referenced_works_count":237,"referenced_works":["https://openalex.org/W34287195","https://openalex.org/W188665287","https://openalex.org/W801844610","https://openalex.org/W1258653530","https://openalex.org/W1498587827","https://openalex.org/W1531753146","https://openalex.org/W1543890504","https://openalex.org/W1555047203","https://openalex.org/W1594815607","https://openalex.org/W1598852815","https://openalex.org/W1641336178","https://openalex.org/W1754557093","https://openalex.org/W1826261498","https://openalex.org/W1835615079","https://openalex.org/W1900540592","https://openalex.org/W1916873495","https://openalex.org/W1944404325","https://openalex.org/W1963493384","https://openalex.org/W1964520746","https://openalex.org/W1965431780","https://openalex.org/W1965568759","https://openalex.org/W1966998932","https://openalex.org/W1967753122","https://openalex.org/W1969938740","https://openalex.org/W1970595154","https://openalex.org/W1970915933","https://openalex.org/W1971060771","https://openalex.org/W1971412744","https://openalex.org/W1972207998","https://openalex.org/W1972875076","https://openalex.org/W1974757133","https://openalex.org/W1975104394","https://openalex.org/W1975584335","https://openalex.org/W1977237795","https://openalex.org/W1979685901","https://openalex.org/W1979955708","https://openalex.org/W1980591242","https://openalex.org/W1981620458","https://openalex.org/W1982087641","https://openalex.org/W1983031752","https://openalex.org/W1984999562","https://openalex.org/W1985585069","https://openalex.org/W1986357982","https://openalex.org/W1987913532","https://openalex.org/W1990567821","https://openalex.org/W1992280242","https://openalex.org/W1993416164","https://openalex.org/W1994511907","https://openalex.org/W1996599316","https://openalex.org/W1996912024","https://openalex.org/W1997988878","https://openalex.org/W1998618468","https://openalex.org/W1998777048","https://openalex.org/W1999817235","https://openalex.org/W2000572318","https://openalex.org/W2001155940","https://openalex.org/W2001173847","https://openalex.org/W2002249795","https://openalex.org/W2002355858","https://openalex.org/W2002683064","https://openalex.org/W2002688249","https://openalex.org/W2003831408","https://openalex.org/W2004423523","https://openalex.org/W2005434843","https://openalex.org/W2007333388","https://openalex.org/W2007571390","https://openalex.org/W2007859564","https://openalex.org/W2010237337","https://openalex.org/W2010474404","https://openalex.org/W2010515415","https://openalex.org/W2010547317","https://openalex.org/W2010743528","https://openalex.org/W2017400416","https://openalex.org/W2019161243","https://openalex.org/W2020691941","https://openalex.org/W2022959880","https://openalex.org/W2023040415","https://openalex.org/W2027034464","https://openalex.org/W2027728353","https://openalex.org/W2029719395","https://openalex.org/W2029904063","https://openalex.org/W2030199762","https://openalex.org/W2031377991","https://openalex.org/W2032792789","https://openalex.org/W2036525359","https://openalex.org/W2036833206","https://openalex.org/W2037876997","https://openalex.org/W2040182956","https://openalex.org/W2041723754","https://openalex.org/W2044616474","https://openalex.org/W2044753677","https://openalex.org/W2044845092","https://openalex.org/W2045589633","https://openalex.org/W2045711626","https://openalex.org/W2047269960","https://openalex.org/W2049157428","https://openalex.org/W2049342310","https://openalex.org/W2050569781","https://openalex.org/W2051301625","https://openalex.org/W2051432136","https://openalex.org/W2051956921","https://openalex.org/W2052767351","https://openalex.org/W2053351302","https://openalex.org/W2053385369","https://openalex.org/W2054701094","https://openalex.org/W2055296003","https://openalex.org/W2055417018","https://openalex.org/W2057671045","https://openalex.org/W2059968421","https://openalex.org/W2060087768","https://openalex.org/W2061616166","https://openalex.org/W2063299495","https://openalex.org/W2065292797","https://openalex.org/W2069347490","https://openalex.org/W2069439733","https://openalex.org/W2070184849","https://openalex.org/W2078477084","https://openalex.org/W2078725182","https://openalex.org/W2080423078","https://openalex.org/W2080823574","https://openalex.org/W2081170157","https://openalex.org/W2083701433","https://openalex.org/W2084381245","https://openalex.org/W2085132889","https://openalex.org/W2085314556","https://openalex.org/W2085775776","https://openalex.org/W2086152184","https://openalex.org/W2087837366","https://openalex.org/W2087896991","https://openalex.org/W2088500487","https://openalex.org/W2088811912","https://openalex.org/W2090455515","https://openalex.org/W2090542192","https://openalex.org/W2090773805","https://openalex.org/W2092668959","https://openalex.org/W2094092533","https://openalex.org/W2095243783","https://openalex.org/W2097813970","https://openalex.org/W2097935950","https://openalex.org/W2099019973","https://openalex.org/W2099118069","https://openalex.org/W2099469211","https://openalex.org/W2100868792","https://openalex.org/W2101616608","https://openalex.org/W2101859789","https://openalex.org/W2104505841","https://openalex.org/W2105785824","https://openalex.org/W2107441200","https://openalex.org/W2107503279","https://openalex.org/W2108444995","https://openalex.org/W2108707301","https://openalex.org/W2110321605","https://openalex.org/W2110975457","https://openalex.org/W2111433192","https://openalex.org/W2111826622","https://openalex.org/W2114702304","https://openalex.org/W2115399432","https://openalex.org/W2116532772","https://openalex.org/W2117328669","https://openalex.org/W2118124054","https://openalex.org/W2118337496","https://openalex.org/W2119147333","https://openalex.org/W2119326753","https://openalex.org/W2119977970","https://openalex.org/W2120010339","https://openalex.org/W2120381403","https://openalex.org/W2121017846","https://openalex.org/W2121998739","https://openalex.org/W2122403976","https://openalex.org/W2122406360","https://openalex.org/W2123226286","https://openalex.org/W2123303875","https://openalex.org/W2127001212","https://openalex.org/W2127168458","https://openalex.org/W2128175263","https://openalex.org/W2128670495","https://openalex.org/W2128801071","https://openalex.org/W2130070646","https://openalex.org/W2130857754","https://openalex.org/W2131686724","https://openalex.org/W2131830004","https://openalex.org/W2134386050","https://openalex.org/W2135102992","https://openalex.org/W2136521447","https://openalex.org/W2137276142","https://openalex.org/W2137357003","https://openalex.org/W2138305199","https://openalex.org/W2139097227","https://openalex.org/W2139406254","https://openalex.org/W2139433233","https://openalex.org/W2139499843","https://openalex.org/W2140600466","https://openalex.org/W2142876519","https://openalex.org/W2145203496","https://openalex.org/W2147822820","https://openalex.org/W2148338861","https://openalex.org/W2149573520","https://openalex.org/W2150164927","https://openalex.org/W2151064288","https://openalex.org/W2152574233","https://openalex.org/W2153260902","https://openalex.org/W2153398041","https://openalex.org/W2153889566","https://openalex.org/W2155312919","https://openalex.org/W2156034369","https://openalex.org/W2157454773","https://openalex.org/W2158909958","https://openalex.org/W2159970646","https://openalex.org/W2161622432","https://openalex.org/W2163016285","https://openalex.org/W2166221624","https://openalex.org/W2171319459","https://openalex.org/W2185212728","https://openalex.org/W2236482561","https://openalex.org/W2238774085","https://openalex.org/W2254216443","https://openalex.org/W2270582783","https://openalex.org/W2285670684","https://openalex.org/W2313598718","https://openalex.org/W2316578169","https://openalex.org/W2384576046","https://openalex.org/W2474599166","https://openalex.org/W2504220478","https://openalex.org/W2509291718","https://openalex.org/W2513566282","https://openalex.org/W2519938316","https://openalex.org/W2539886351","https://openalex.org/W2587797478","https://openalex.org/W2589731238","https://openalex.org/W2603489900","https://openalex.org/W4229861519","https://openalex.org/W4231712773","https://openalex.org/W4249795333","https://openalex.org/W6601428164","https://openalex.org/W6733498347","https://openalex.org/W6736304676","https://openalex.org/W7095603623"],"related_works":["https://openalex.org/W4385982696","https://openalex.org/W2388222041","https://openalex.org/W2398151825","https://openalex.org/W2150953401","https://openalex.org/W2596092589","https://openalex.org/W2050425010","https://openalex.org/W2349886552","https://openalex.org/W1999500450","https://openalex.org/W2900187612","https://openalex.org/W2962004347"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":26},{"year":2024,"cited_by_count":29},{"year":2023,"cited_by_count":19},{"year":2022,"cited_by_count":32},{"year":2021,"cited_by_count":57},{"year":2020,"cited_by_count":41},{"year":2019,"cited_by_count":49},{"year":2018,"cited_by_count":35},{"year":2017,"cited_by_count":10}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-03-16T00:00:00"}
