{"id":"https://openalex.org/W2593385508","doi":"https://doi.org/10.1016/j.virol.2017.02.022","title":"CXCL9 compensates for the absence of CXCL10 during recurrent Herpetic stromal keratitis","display_name":"CXCL9 compensates for the absence of CXCL10 during recurrent Herpetic stromal keratitis","publication_year":2017,"publication_date":"2017-03-07","ids":{"openalex":"https://openalex.org/W2593385508","doi":"https://doi.org/10.1016/j.virol.2017.02.022","mag":"2593385508","pmid":"https://pubmed.ncbi.nlm.nih.gov/28282568","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5401772"},"language":"en","primary_location":{"id":"doi:10.1016/j.virol.2017.02.022","doi":"https://doi.org/10.1016/j.virol.2017.02.022","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.virol.2017.02.022","pdf_url":null,"source":{"id":"https://openalex.org/S6147291","display_name":"Virology","issn_l":"0042-6822","issn":["0042-6822","1089-862X","1096-0341"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.virol.2017.02.022","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047850095","display_name":"Deena A. Tajfirouz","orcid":"https://orcid.org/0000-0001-8419-8728","observed_orcids":["https://orcid.org/0000-0001-8419-8728"]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deena Tajfirouz","raw_affiliation_strings":["Department of Ophthalmology, Saint Louis University School of Medicine, St. Louis, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Saint Louis University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I47838141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070462631","display_name":"Devin M. West","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Devin M. West","raw_affiliation_strings":["Department of Ophthalmology, Saint Louis University School of Medicine, St. Louis, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Saint Louis University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I47838141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109254662","display_name":"Xiao-Tang Yin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiao-Tang Yin","raw_affiliation_strings":["Department of Ophthalmology, Saint Louis University School of Medicine, St. Louis, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Saint Louis University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I47838141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029988676","display_name":"Chloe A. Potter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chloe A. Potter","raw_affiliation_strings":["Department of Ophthalmology, Saint Louis University School of Medicine, St. Louis, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Saint Louis University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I47838141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046722897","display_name":"Robyn S. Klein","orcid":"https://orcid.org/0000-0003-0281-1352","observed_orcids":["https://orcid.org/0000-0003-0281-1352"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robyn Klein","raw_affiliation_strings":["Departments of Medicine, Pathology & Immunology, Anatomy & Neurobiology Washington University School of Medicine, Saint Louis, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine, Pathology & Immunology, Anatomy & Neurobiology Washington University School of Medicine, Saint Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045207583","display_name":"Patrick M. Stuart","orcid":"https://orcid.org/0000-0003-1747-351X","observed_orcids":["https://orcid.org/0000-0003-1747-351X"]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Patrick M. Stuart","raw_affiliation_strings":["Department of Ophthalmology, Saint Louis University School of Medicine, St. Louis, MO, USA. Electronic address: pstuart2@slu.edu","Department of Ophthalmology, Saint Louis University School of Medicine, St. Louis, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Saint Louis University School of Medicine, St. Louis, MO, USA. Electronic address: pstuart2@slu.edu","institution_ids":["https://openalex.org/I47838141"]},{"raw_affiliation_string":"Department of Ophthalmology, Saint Louis University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I47838141"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5045207583"],"corresponding_institution_ids":["https://openalex.org/I47838141"],"apc_list":{"value":3160,"currency":"USD","value_usd":3160},"apc_paid":null,"fwci":0.8564,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.73013209,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"506","issue":null,"first_page":"7","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.4943999946117401,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.4943999946117401,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11532","display_name":"Chemokine receptors and signaling","score":0.3481000065803528,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.09989999979734421,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/herpetic-stromal-keratitis","display_name":"herpetic stromal keratitis","score":0.9470000267028809},{"id":"https://openalex.org/keywords/cxcl9","display_name":"CXCL9","score":0.8539999723434448},{"id":"https://openalex.org/keywords/cxcl10","display_name":"CXCL10","score":1.0},{"id":"https://openalex.org/keywords/chemokines","display_name":"chemokines","score":0.9020000100135803},{"id":"https://openalex.org/keywords/hsv-1-reactivation","display_name":"HSV-1 reactivation","score":0.8830000162124634},{"id":"https://openalex.org/keywords/keratitis","display_name":"keratitis","score":0.8240000009536743},{"id":"https://openalex.org/keywords/neutralizing-antibodies","display_name":"neutralizing antibodies","score":0.7269999980926514},{"id":"https://openalex.org/keywords/leukocyte-recruitment","display_name":"leukocyte recruitment","score":0.6600000262260437}],"concepts":[{"id":"https://openalex.org/C17502307","wikidata":"https://www.wikidata.org/wiki/Q411999","display_name":"CXCL9","level":5,"score":0.8504691123962402},{"id":"https://openalex.org/C5858377","wikidata":"https://www.wikidata.org/wiki/Q986112","display_name":"CXCL10","level":4,"score":0.8308318853378296},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.5309319496154785},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.516205370426178},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.46653372049331665},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.38417163491249084},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.37984511256217957},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.2664337158203125}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003315","descriptor_name":"Cornea","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003315","descriptor_name":"Cornea","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015854","descriptor_name":"Up-Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016849","descriptor_name":"Keratitis, Herpetic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016849","descriptor_name":"Keratitis, Herpetic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016849","descriptor_name":"Keratitis, Herpetic","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D018259","descriptor_name":"Herpesvirus 1, Human","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018259","descriptor_name":"Herpesvirus 1, Human","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054357","descriptor_name":"Chemokine CXCL10","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D054357","descriptor_name":"Chemokine CXCL10","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D054370","descriptor_name":"Chemokine CXCL9","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D054370","descriptor_name":"Chemokine CXCL9","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.virol.2017.02.022","doi":"https://doi.org/10.1016/j.virol.2017.02.022","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.virol.2017.02.022","pdf_url":null,"source":{"id":"https://openalex.org/S6147291","display_name":"Virology","issn_l":"0042-6822","issn":["0042-6822","1089-862X","1096-0341"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virology","raw_type":"journal-article"},{"id":"pmid:28282568","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28282568","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:4926361","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5401772","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5401772","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5401772","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Virology","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.virol.2017.02.022","doi":"https://doi.org/10.1016/j.virol.2017.02.022","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.virol.2017.02.022","pdf_url":null,"source":{"id":"https://openalex.org/S6147291","display_name":"Virology","issn_l":"0042-6822","issn":["0042-6822","1089-862X","1096-0341"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1874686252","display_name":"Center for the Study of Immune Mechanisms of Flavivirus Control","funder_award_id":"U19AI083019","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5276344472","display_name":"THE ROLE OF APOPTOTIC MOLECULES IN HERPETIC STROMAL","funder_award_id":"R01EY016352","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G5441180306","display_name":"Neuroprotection and repair during West Nile Virus Encephalitis","funder_award_id":"R01NS052632","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G6705862152","display_name":"Amelioration of recurrent herpes keratitis","funder_award_id":"R01EY011885","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G717917886","display_name":null,"funder_award_id":"HDTRA-1-15-1-0032","funder_id":"https://openalex.org/F4320332186","funder_display_name":"Defense Threat Reduction Agency"},{"id":"https://openalex.org/G8350336334","display_name":"Mechanisms of HSK amelioration","funder_award_id":"R01EY021247","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G9000034168","display_name":null,"funder_award_id":"AI083019","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306811","display_name":"Research to Prevent Blindness","ror":"https://ror.org/04drjs621"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332186","display_name":"Defense Threat Reduction Agency","ror":"https://ror.org/04tz64554"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W191335833","https://openalex.org/W197411503","https://openalex.org/W1445717942","https://openalex.org/W1575243854","https://openalex.org/W1601751138","https://openalex.org/W1621936179","https://openalex.org/W1773015384","https://openalex.org/W1779967726","https://openalex.org/W1823467089","https://openalex.org/W1966447073","https://openalex.org/W1972543205","https://openalex.org/W1990205485","https://openalex.org/W1991921545","https://openalex.org/W2002511862","https://openalex.org/W2010905723","https://openalex.org/W2019294221","https://openalex.org/W2030301104","https://openalex.org/W2035153897","https://openalex.org/W2036348588","https://openalex.org/W2041828051","https://openalex.org/W2041971973","https://openalex.org/W2053583874","https://openalex.org/W2054332590","https://openalex.org/W2056712418","https://openalex.org/W2060523362","https://openalex.org/W2070452447","https://openalex.org/W2075089210","https://openalex.org/W2084727005","https://openalex.org/W2086483875","https://openalex.org/W2094565610","https://openalex.org/W2096106951","https://openalex.org/W2097181547","https://openalex.org/W2097989138","https://openalex.org/W2111675697","https://openalex.org/W2114978872","https://openalex.org/W2133241248","https://openalex.org/W2139485237","https://openalex.org/W2144262617","https://openalex.org/W2157265986","https://openalex.org/W2158825435","https://openalex.org/W2168899864","https://openalex.org/W2169158338","https://openalex.org/W2497820450","https://openalex.org/W4211052952","https://openalex.org/W6607837391"],"related_works":["https://openalex.org/W2096106951","https://openalex.org/W2111675697","https://openalex.org/W4313354643","https://openalex.org/W2139100262","https://openalex.org/W2094446542","https://openalex.org/W2094565610","https://openalex.org/W2158825435","https://openalex.org/W2610214705","https://openalex.org/W4310235712","https://openalex.org/W1645084893"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2017-03-16T00:00:00"}