{"id":"https://openalex.org/W2593136238","doi":null,"title":"Formulation and Evaluation of Cetirizine HCl Mouth FastDissolving Tablets","display_name":"Formulation and Evaluation of Cetirizine HCl Mouth FastDissolving Tablets","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2593136238","mag":"2593136238"},"language":"en","primary_location":{"id":"mag:2593136238","doi":null,"is_oa":false,"landing_page_url":"https://www.scholarsresearchlibrary.com/articles/formulation-and-evaluation-of-cetirizine-hcl-mouth-fastdissolving-tablets.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306507771","display_name":"Der pharmacia lettre","issn_l":"0975-5071","issn":["0975-5071"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Der pharmacia lettre","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029017041","display_name":"rasekhar Patro","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"rasekhar Patro","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108624022","display_name":"S Sreenivas Patro","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Sreenivas Patro","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101715963","display_name":"Bibhu Prasad Panda","orcid":"https://orcid.org/0000-0002-7392-4883","observed_orcids":["https://orcid.org/0000-0002-7392-4883","https://orcid.org/0000-0001-5110-2945"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bibhu Prasad Panda","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7392-4883","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5112858082","display_name":"Muddana Eswara Bhanoji Rao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Muddana Eswara Bhanoji Rao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8492,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.65986696,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"3","issue":"4","first_page":"63","last_page":"70"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.020400000736117363,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12547","display_name":"Pharmaceutical studies and practices","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cetirizine-hydrochloride","display_name":"cetirizine hydrochloride","score":0.9919999837875366},{"id":"https://openalex.org/keywords/superdisintegrants","display_name":"superdisintegrants","score":0.9490000009536743},{"id":"https://openalex.org/keywords/croscarmellose-sodium","display_name":"croscarmellose sodium","score":0.9980000257492065},{"id":"https://openalex.org/keywords/crospovidone","display_name":"crospovidone","score":0.9959999918937683},{"id":"https://openalex.org/keywords/sodium-starch-glycolate","display_name":"sodium starch glycolate","score":0.9990000128746033},{"id":"https://openalex.org/keywords/disintegration-time","display_name":"disintegration time","score":0.7929999828338623},{"id":"https://openalex.org/keywords/drug-release","display_name":"drug release","score":0.9599999785423279},{"id":"https://openalex.org/keywords/direct-compression","display_name":"direct compression","score":0.6470000147819519},{"id":"https://openalex.org/keywords/formulation-optimization","display_name":"formulation optimization","score":0.6060000061988831},{"id":"https://openalex.org/keywords/stability-studies","display_name":"stability studies","score":0.6190000176429749},{"id":"https://openalex.org/keywords/treatment-adherence","display_name":"medication adherence","score":0.5199999809265137}],"concepts":[{"id":"https://openalex.org/C2777091354","wikidata":"https://www.wikidata.org/wiki/Q5188058","display_name":"Croscarmellose sodium","level":4,"score":0.9777995944023132},{"id":"https://openalex.org/C191168616","wikidata":"https://www.wikidata.org/wiki/Q5503337","display_name":"Friability","level":4,"score":0.8875130414962769},{"id":"https://openalex.org/C77281830","wikidata":"https://www.wikidata.org/wiki/Q718608","display_name":"Dosage form","level":2,"score":0.5744565725326538},{"id":"https://openalex.org/C2778572730","wikidata":"https://www.wikidata.org/wiki/Q416713","display_name":"Magnesium stearate","level":3,"score":0.5055413246154785},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.48536741733551025},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.4664708077907562},{"id":"https://openalex.org/C88380143","wikidata":"https://www.wikidata.org/wiki/Q416674","display_name":"Dissolution","level":2,"score":0.4165636897087097},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.37404125928878784},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3569245934486389},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3076269030570984},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.2856346070766449},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24524155259132385},{"id":"https://openalex.org/C201253974","wikidata":"https://www.wikidata.org/wiki/Q1330121","display_name":"First pass effect","level":3,"score":0.14469954371452332},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.11539244651794434}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2593136238","doi":null,"is_oa":false,"landing_page_url":"https://www.scholarsresearchlibrary.com/articles/formulation-and-evaluation-of-cetirizine-hcl-mouth-fastdissolving-tablets.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306507771","display_name":"Der pharmacia lettre","issn_l":"0975-5071","issn":["0975-5071"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Der pharmacia lettre","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":2,"referenced_works":["https://openalex.org/W565789936","https://openalex.org/W2159269801"],"related_works":["https://openalex.org/W2028463906","https://openalex.org/W7098003719","https://openalex.org/W6893960937","https://openalex.org/W2999683939","https://openalex.org/W7220507761","https://openalex.org/W4392391726","https://openalex.org/W7100024314","https://openalex.org/W8880792","https://openalex.org/W3139903152","https://openalex.org/W2185970674"],"abstract_inverted_index":{"Mouth":[0],"Fast":[1],"Dissolving":[2],"Tablets":[3,98],"(MFDT\u2019s)":[4],"have":[5],"emerged":[6],"as":[7],"an":[8],"alternative":[9],"to":[10,15,21,36,76,148],"conventional":[11,38],"oral":[12,56],"dosage":[13,40,47],"forms":[14,41,48],"improve":[16],"the":[17,28,55,65,130,134],"patient":[18],"compliance.":[19],"Due":[20],"problem":[22],"in":[23,54,60,133],"swallowing":[24],"ability":[25],"with":[26,142],"age,":[27],"pediatric":[29],"and":[30,78,105,114,129,157],"geriatric":[31],"patients":[32],"complain":[33],"of":[34,67,72,86,166],"difficulty":[35],"take":[37],"solid":[39,46],".":[42],"The":[43,69,136],"MFDT\u2019s":[44,82],"are":[45],"that":[49,121,139,170],"dissolve":[50],"or":[51,62],"disintegrate":[52],"rapidly":[53],"cavity,":[57],"which":[58,151],"results":[59,137],"solution":[61],"suspension":[63],"without":[64],"need":[66],"water.":[68],"main":[70],"objective":[71],"this":[73],"work":[74],"is":[75,172],"formulate":[77],"evaluate":[79],"Cetirizine":[80,127],"HCl":[81,128],"using":[83],"different":[84],"concentrations":[85],"superdisintegrants":[87],"like":[88],"croscarmellose":[89,144],"sodium":[90,94,145],"(CCS),":[91],"crospovidone":[92],"(CP),":[93],"starch":[95],"glycolate":[96],"(SSG).":[97],"were":[99],"prepared":[100,141],"by":[101],"direct":[102],"compression":[103],"method":[104],"evaluated":[106],"for":[107],"hardness,":[108],"friability,":[109],"wetting":[110],"time,":[111],"disintegration":[112,159],"time":[113,160],"percent":[115],"drug":[116,154],"release.":[117],"FT-IR":[118],"studies":[119,165],"revealed":[120,169],"there":[122],"was":[123,146],"no":[124],"interaction":[125],"between":[126],"excipients":[131],"used":[132],"study.":[135],"indicate":[138],"formulation":[140,168,171],"5%":[143],"found":[147],"be":[149],"optimized":[150,167],"provides":[152],"maximum":[153],"release":[155],"(99%)":[156],"minimum":[158],"(less":[161],"than":[162],"20sec).":[163],"Stability":[164],"stable.":[173]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2017-03-16T00:00:00"}