{"id":"https://openalex.org/W2592964223","doi":"https://doi.org/10.1080/13697137.2017.1284780","title":"Systematic indirect comparison of ospemifene versus local estrogens for vulvar and vaginal atrophy","display_name":"Systematic indirect comparison of ospemifene versus local estrogens for vulvar and vaginal atrophy","publication_year":2017,"publication_date":"2017-03-07","ids":{"openalex":"https://openalex.org/W2592964223","doi":"https://doi.org/10.1080/13697137.2017.1284780","mag":"2592964223","pmid":"https://pubmed.ncbi.nlm.nih.gov/28267367"},"language":"en","primary_location":{"id":"doi:10.1080/13697137.2017.1284780","doi":"https://doi.org/10.1080/13697137.2017.1284780","is_oa":true,"landing_page_url":"https://doi.org/10.1080/13697137.2017.1284780","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/13697137.2017.1284780?needAccess=true","source":{"id":"https://openalex.org/S110024640","display_name":"Climacteric","issn_l":"1369-7137","issn":["1369-7137","1473-0804"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Climacteric","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.tandfonline.com/doi/pdf/10.1080/13697137.2017.1284780?needAccess=true","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076687331","display_name":"Nico Bruyniks","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"N. Bruyniks","raw_affiliation_strings":["BrInPhar Ltd, Iver Heath, Buckinghamshire, UK;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BrInPhar Ltd, Iver Heath, Buckinghamshire, UK;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089876284","display_name":"Nicoletta Biglia","orcid":"https://orcid.org/0000-0003-1009-5309","observed_orcids":["https://orcid.org/0000-0003-1009-5309","https://orcid.org/0000-0002-1939-018X"]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"N. Biglia","raw_affiliation_strings":["Department of Oncological Gynaecology, University of Turin, Mauriziano \u2018Umberto I\u2019 Hospital, Turin, Italy;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncological Gynaecology, University of Turin, Mauriziano \u2018Umberto I\u2019 Hospital, Turin, Italy;","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068621774","display_name":"Santiago Palacios","orcid":"https://orcid.org/0000-0003-2229-1200","observed_orcids":["https://orcid.org/0000-0003-2229-1200"]},"institutions":[{"id":"https://openalex.org/I4210109638","display_name":"Instituto Palacios","ror":"https://ror.org/01kvepn75","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210109638"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"S. Palacios","raw_affiliation_strings":["Instituto Palacios, Salud y Medicina de la Mujer, Madrid, Spain;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Palacios, Salud y Medicina de la Mujer, Madrid, Spain;","institution_ids":["https://openalex.org/I4210109638"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113084000","display_name":"A. O. Mueck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["CN","DE"],"is_corresponding":false,"raw_author_name":"A. O. Mueck","raw_affiliation_strings":["Department of Gynecological Endocrinology, Beijing OB/GYN Hospital, Capital Medical University, Beijing, China","Department of Women\u2019s Health, University of T\u00fcbingen, T\u00fcbingen, Germany;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecological Endocrinology, Beijing OB/GYN Hospital, Capital Medical University, Beijing, China","institution_ids":["https://openalex.org/I183519381"]},{"raw_affiliation_string":"Department of Women\u2019s Health, University of T\u00fcbingen, T\u00fcbingen, Germany;","institution_ids":["https://openalex.org/I8087733"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5076687331"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4989,"has_fulltext":true,"cited_by_count":29,"citation_normalized_percentile":{"value":0.45676541,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"20","issue":"3","first_page":"195","last_page":"204"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10459","display_name":"Sexual function and dysfunction studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ospemifene","display_name":"ospemifene","score":1.0},{"id":"https://openalex.org/keywords/vulvar-atrophy","display_name":"vulvar atrophy","score":0.8799999952316284},{"id":"https://openalex.org/keywords/vaginal-atrophy","display_name":"vaginal atrophy","score":0.9890000224113464},{"id":"https://openalex.org/keywords/estradiol","display_name":"estradiol","score":0.8679999709129333},{"id":"https://openalex.org/keywords/estriol","display_name":"estriol","score":0.8149999976158142},{"id":"https://openalex.org/keywords/vaginal-ph","display_name":"vaginal pH","score":0.8050000071525574},{"id":"https://openalex.org/keywords/endometrial-safety","display_name":"endometrial safety","score":0.9350000023841858},{"id":"https://openalex.org/keywords/breast-cancer-risk","display_name":"breast cancer risk","score":0.7770000100135803},{"id":"https://openalex.org/keywords/venous-thromboembolism","display_name":"venous thromboembolism","score":0.9890000224113464},{"id":"https://openalex.org/keywords/menopause","display_name":"menopause","score":0.4970000088214874},{"id":"https://openalex.org/keywords/indirect-comparison","display_name":"indirect comparison","score":0.4189999997615814}],"concepts":[{"id":"https://openalex.org/C2777335581","wikidata":"https://www.wikidata.org/wiki/Q409721","display_name":"Estriol","level":3,"score":0.8945735096931458},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.876314640045166},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.7735427618026733},{"id":"https://openalex.org/C2776917545","wikidata":"https://www.wikidata.org/wiki/Q4007235","display_name":"Vaginal atrophy","level":3,"score":0.7607811689376831},{"id":"https://openalex.org/C2777689261","wikidata":"https://www.wikidata.org/wiki/Q686574","display_name":"Endometrial hyperplasia","level":3,"score":0.4947459399700165},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.47616952657699585},{"id":"https://openalex.org/C2777088508","wikidata":"https://www.wikidata.org/wiki/Q944777","display_name":"Endometrial cancer","level":3,"score":0.4571218192577362},{"id":"https://openalex.org/C2777744392","wikidata":"https://www.wikidata.org/wiki/Q5880","display_name":"Vagina","level":2,"score":0.4352720081806183},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4241051971912384},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.42271408438682556},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4176813066005707},{"id":"https://openalex.org/C2778562196","wikidata":"https://www.wikidata.org/wiki/Q177708","display_name":"Menopause","level":2,"score":0.4118995666503906},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.3155316412448883},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.19550436735153198},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.17205306887626648},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.15185576677322388},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000279","descriptor_name":"Administration, Cutaneous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001284","descriptor_name":"Atrophy","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D004414","descriptor_name":"Dyspareunia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D004958","descriptor_name":"Estradiol","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D004958","descriptor_name":"Estradiol","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008593","descriptor_name":"Menopause","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013629","descriptor_name":"Tamoxifen","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D013629","descriptor_name":"Tamoxifen","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D013629","descriptor_name":"Tamoxifen","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D014621","descriptor_name":"Vagina","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D014844","descriptor_name":"Vulva","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020845","descriptor_name":"Selective Estrogen Receptor Modulators","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D020845","descriptor_name":"Selective Estrogen Receptor Modulators","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1080/13697137.2017.1284780","doi":"https://doi.org/10.1080/13697137.2017.1284780","is_oa":true,"landing_page_url":"https://doi.org/10.1080/13697137.2017.1284780","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/13697137.2017.1284780?needAccess=true","source":{"id":"https://openalex.org/S110024640","display_name":"Climacteric","issn_l":"1369-7137","issn":["1369-7137","1473-0804"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Climacteric","raw_type":"journal-article"},{"id":"pmid:28267367","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28267367","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Climacteric : the journal of the International Menopause Society","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unito.it:2318/1632660","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2318/1632660","pdf_url":"https://iris.unito.it/bitstream/2318/1632660/2/Systematic%20indirect%20comparison%20of%20ospemifene%20versus%20local%20estrogens%20for%20vulvar%20and%20vaginal%20atrophy.pdf","source":{"id":"https://openalex.org/S4306400637","display_name":"Institutional Research Information System University of Turin (University of Turin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I55143463","host_organization_name":"University of Turin","host_organization_lineage":["https://openalex.org/I55143463"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1080/13697137.2017.1284780","doi":"https://doi.org/10.1080/13697137.2017.1284780","is_oa":true,"landing_page_url":"https://doi.org/10.1080/13697137.2017.1284780","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/13697137.2017.1284780?needAccess=true","source":{"id":"https://openalex.org/S110024640","display_name":"Climacteric","issn_l":"1369-7137","issn":["1369-7137","1473-0804"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Climacteric","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321863","display_name":"Gedeon Richter","ror":"https://ror.org/0033rtn64"},{"id":"https://openalex.org/F4320323316","display_name":"Shionogi","ror":"https://ror.org/01v3bqg10"},{"id":"https://openalex.org/F4320327235","display_name":"Servier","ror":"https://ror.org/034e7c066"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2592964223.pdf","grobid_xml":"https://content.openalex.org/works/W2592964223.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1941294854","https://openalex.org/W1964996262","https://openalex.org/W1965726545","https://openalex.org/W1968357961","https://openalex.org/W1984565138","https://openalex.org/W1984670037","https://openalex.org/W1987272164","https://openalex.org/W1994597465","https://openalex.org/W1995505704","https://openalex.org/W2011779669","https://openalex.org/W2013230144","https://openalex.org/W2014456124","https://openalex.org/W2016237674","https://openalex.org/W2021197391","https://openalex.org/W2023994524","https://openalex.org/W2028931582","https://openalex.org/W2070506018","https://openalex.org/W2077443619","https://openalex.org/W2079795132","https://openalex.org/W2087848219","https://openalex.org/W2098455101","https://openalex.org/W2100392631","https://openalex.org/W2101800519","https://openalex.org/W2144828551","https://openalex.org/W2152612314","https://openalex.org/W2176311654","https://openalex.org/W2312833310","https://openalex.org/W2322960915","https://openalex.org/W4210972163","https://openalex.org/W4244853583"],"related_works":["https://openalex.org/W2013230144","https://openalex.org/W4382198668","https://openalex.org/W2160489493","https://openalex.org/W4366082089","https://openalex.org/W2070506018","https://openalex.org/W2098948800","https://openalex.org/W3017568968","https://openalex.org/W1965726545","https://openalex.org/W2011779669","https://openalex.org/W2015437083"],"abstract_inverted_index":{")":[0],"vs.":[1],"local":[2,25,245],"vaginal":[3,11,26,74,124,182,246],"estrogens":[4,27,247],"in":[5,28,31,65,96,248],"moderate":[6],"or":[7,147,161,176,186,207,242],"severe":[8],"vulvar":[9],"and":[10,41,63,76,88,106,110,115,127,149,172,194,237],"atrophy":[12],"(VVA).":[13],"A":[14],"literature":[15],"search":[16],"was":[17,99,179],"carried":[18],"out":[19],"of":[20,24,42,200,251],"clinical":[21],"efficacy/safety":[22],"trials":[23],"VVA":[29],"approved":[30],"Europe.":[32],"For":[33,46],"efficacy":[34],"comparison,":[35,48],"studies":[36,49],"had":[37,50],"to":[38,51,69,192,241],"be":[39,52],"placebo-controlled":[40],"12":[43,71,119],"weeks'":[44,54],"duration.":[45,55],"safety":[47],"\u226540":[53],"Efficacy":[56],"endpoints":[57,81],"were":[58,82,129,142,159],"the":[59,121,212,249],"difference":[60],"between":[61],"active":[62],"placebo":[64,95,158,193],"change":[66],"from":[67],"baseline":[68],"week":[70],"for":[72,102,111,131,197,215],"symptoms,":[73],"pH,":[75],"maturation":[77],"value":[78],"(MV).":[79],"Safety":[80],"endometrial":[83,184],"safety,":[84,86,236],"breast":[85,189],"thrombosis,":[87],"adverse":[89],"events.":[90],"The":[91,153],"12-week":[92,154],"improvement":[93],"over":[94,157],"symptom":[97],"score":[98],"not":[100,219],"different":[101],"ospemifene":[103,112,132,150,164,204,230],"60":[104,113,133,151,165,205,231],"mg":[105,114,134,166,206,232],"17\u03b2-estradiol":[107,171],"10":[108,136,169,208],"\u03bcg":[109,137,170,209],"estriol":[116,145,174],"gel.":[117,177],"After":[118],"weeks,":[120],"percentages":[122],"with":[123,144,163,168,173,203],"pH":[125,140],"<5.0":[126],"<5.5":[128],"better":[130,162,243],"than":[135,244],"17\u03b2-estradiol.":[138],"Week-12":[139],"changes":[141],"comparable":[143,240],"pessaries":[146,175],"gel":[148],"mg.":[152],"MV":[155],"improvements":[156],"similar":[160],"compared":[167],"There":[178],"no":[180,195],"increased":[181,198,222],"bleeding,":[183],"hyperplasia,":[185],"carcinoma":[187],"(including":[188],"cancer)":[190],"relative":[191],"signal":[196],"risk":[199],"venous":[201],"thromboembolism":[202],"17\u03b2-estradiol,":[210],"but":[211],"confidence":[213],"intervals":[214],"both":[216],"products":[217],"do":[218],"exclude":[220],"an":[221,234],"risk.":[223],"This":[224],"historical":[225],"indirect":[226],"comparison":[227],"suggests":[228],"that":[229],"has":[233],"efficacy,":[235],"tolerability":[238],"profile":[239],"treatment":[250],"VVA.":[252]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2017-03-16T00:00:00"}