{"id":"https://openalex.org/W2592905069","doi":null,"title":"Disinfection by-products and public health concerns","display_name":"Disinfection by-products and public health concerns","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W2592905069","mag":"2592905069"},"language":"en","primary_location":{"id":"pmh:oai:pure.atira.dk:publications/edefda65-815a-416e-b156-70f0b0fc54c7","doi":null,"is_oa":false,"landing_page_url":"https://research-repository.uwa.edu.au/en/publications/disinfection-byproducts-and-public-health-concerns(edefda65-815a-416e-b156-70f0b0fc54c7).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306402492","display_name":"UWA Profiles and Research Repository (UWA)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"McAuley, K 2008, 'Disinfection by-products and public health concerns', Doctor of Philosophy.","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056765701","display_name":"Kimberley McAuley","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Kimberley McAuley","raw_affiliation_strings":["School of Population and Global Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Population and Global Health","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5056765701"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11493","display_name":"Water Treatment and Disinfection","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11493","display_name":"Water Treatment and Disinfection","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10122","display_name":"Toxic Organic Pollutants Impact","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/disinfection-by-products","display_name":"disinfection by-products","score":0.9980000257492065},{"id":"https://openalex.org/keywords/trihalomethanes","display_name":"trihalomethanes","score":0.9679999947547913},{"id":"https://openalex.org/keywords/drinking-water","display_name":"drinking water","score":0.531000018119812},{"id":"https://openalex.org/keywords/adverse-pregnancy-outcomes","display_name":"adverse pregnancy outcomes","score":0.7940000295639038},{"id":"https://openalex.org/keywords/congenital-malformations","display_name":"congenital malformations","score":0.9890000224113464},{"id":"https://openalex.org/keywords/birth-weight","display_name":"birth weight","score":0.7540000081062317},{"id":"https://openalex.org/keywords/teratogenicity","display_name":"teratogenicity","score":0.5920000076293945},{"id":"https://openalex.org/keywords/asthma-symptoms","display_name":"asthma symptoms","score":0.5569999814033508},{"id":"https://openalex.org/keywords/water-use-patterns","display_name":"water consumption patterns","score":0.30300000309944153},{"id":"https://openalex.org/keywords/dose-response-modeling","display_name":"dose-response modeling","score":0.7099999785423279},{"id":"https://openalex.org/keywords/population-risk-assessment","display_name":"population risk assessment","score":0.6079999804496765},{"id":"https://openalex.org/keywords/brominated-trihalomethanes","display_name":"brominated trihalomethanes","score":0.6859999895095825},{"id":"https://openalex.org/keywords/chloroform","display_name":"chloroform","score":0.6079999804496765},{"id":"https://openalex.org/keywords/trichloroethane","display_name":"trichloroethane","score":0.5929999947547913},{"id":"https://openalex.org/keywords/trichloroacetic-acid","display_name":"trichloroacetic acid","score":0.6340000033378601}],"concepts":[{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.5863276124000549},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.5101452469825745},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.3897186815738678},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27538010478019714},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.12292036414146423}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:pure.atira.dk:publications/edefda65-815a-416e-b156-70f0b0fc54c7","doi":null,"is_oa":false,"landing_page_url":"https://research-repository.uwa.edu.au/en/publications/disinfection-byproducts-and-public-health-concerns(edefda65-815a-416e-b156-70f0b0fc54c7).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306402492","display_name":"UWA Profiles and Research Repository (UWA)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"McAuley, K 2008, 'Disinfection by-products and public health concerns', Doctor of Philosophy.","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2592905069","doi":null,"is_oa":false,"landing_page_url":"https://research-repository.uwa.edu.au/en/publications/disinfection-by-products-and-public-health-concerns","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0},{"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation","score":0.9090999960899353}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":266,"referenced_works":["https://openalex.org/W103238771","https://openalex.org/W183890281","https://openalex.org/W619316582","https://openalex.org/W1517264744","https://openalex.org/W1518620277","https://openalex.org/W1531378508","https://openalex.org/W1552528612","https://openalex.org/W1891743807","https://openalex.org/W1899232072","https://openalex.org/W1902072415","https://openalex.org/W1923879462","https://openalex.org/W1951579886","https://openalex.org/W1963520129","https://openalex.org/W1967099345","https://openalex.org/W1967217296","https://openalex.org/W1967677705","https://openalex.org/W1968334838","https://openalex.org/W1971508976","https://openalex.org/W1971861957","https://openalex.org/W1973771183","https://openalex.org/W1974241425","https://openalex.org/W1975693534","https://openalex.org/W1977288756","https://openalex.org/W1978300494","https://openalex.org/W1978370636","https://openalex.org/W1979581878","https://openalex.org/W1980946892","https://openalex.org/W1980968026","https://openalex.org/W1981005451","https://openalex.org/W1981383044","https://openalex.org/W1981952056","https://openalex.org/W1983858586","https://openalex.org/W1984748642","https://openalex.org/W1985952494","https://openalex.org/W1985985738","https://openalex.org/W1986374861","https://openalex.org/W1986529150","https://openalex.org/W1987467764","https://openalex.org/W1987468589","https://openalex.org/W1989080288","https://openalex.org/W1989479058","https://openalex.org/W1989546305","https://openalex.org/W1991251169","https://openalex.org/W1991433775","https://openalex.org/W1992831474","https://openalex.org/W1993696816","https://openalex.org/W1994315019","https://openalex.org/W1995892514","https://openalex.org/W1996453719","https://openalex.org/W1996804217","https://openalex.org/W1996844281","https://openalex.org/W1996958665","https://openalex.org/W1998222043","https://openalex.org/W1999063801","https://openalex.org/W1999628093","https://openalex.org/W2001102616","https://openalex.org/W2001240161","https://openalex.org/W2001714341","https://openalex.org/W2002079571","https://openalex.org/W2002170101","https://openalex.org/W2002243129","https://openalex.org/W2002794671","https://openalex.org/W2002902717","https://openalex.org/W2003525306","https://openalex.org/W2004030256","https://openalex.org/W2005305235","https://openalex.org/W2005949412","https://openalex.org/W2006581532","https://openalex.org/W2006591502","https://openalex.org/W2007262872","https://openalex.org/W2007414662","https://openalex.org/W2007966145","https://openalex.org/W2009783449","https://openalex.org/W2010234486","https://openalex.org/W2010332398","https://openalex.org/W2010346458","https://openalex.org/W2010347552","https://openalex.org/W2010826423","https://openalex.org/W2012568723","https://openalex.org/W2013262495","https://openalex.org/W2014429819","https://openalex.org/W2015919772","https://openalex.org/W2016542958","https://openalex.org/W2017404306","https://openalex.org/W2017493567","https://openalex.org/W2018199533","https://openalex.org/W2018284275","https://openalex.org/W2018683215","https://openalex.org/W2019607388","https://openalex.org/W2021294296","https://openalex.org/W2022644182","https://openalex.org/W2023217836","https://openalex.org/W2025457841","https://openalex.org/W2025465718","https://openalex.org/W2025640607","https://openalex.org/W2025659707","https://openalex.org/W2025869885","https://openalex.org/W2026471340","https://openalex.org/W2027713155","https://openalex.org/W2028556059","https://openalex.org/W2029255067","https://openalex.org/W2030115335","https://openalex.org/W2030124467","https://openalex.org/W2030330889","https://openalex.org/W2030846250","https://openalex.org/W2031071742","https://openalex.org/W2031608214","https://openalex.org/W2032486047","https://openalex.org/W2032858087","https://openalex.org/W2035246735","https://openalex.org/W2035594562","https://openalex.org/W2035843057","https://openalex.org/W2036245115","https://openalex.org/W2036308693","https://openalex.org/W2036453518","https://openalex.org/W2037002370","https://openalex.org/W2037230697","https://openalex.org/W2037356687","https://openalex.org/W2037382441","https://openalex.org/W2038655998","https://openalex.org/W2040823633","https://openalex.org/W2040849784","https://openalex.org/W2041297313","https://openalex.org/W2041644112","https://openalex.org/W2041724669","https://openalex.org/W2042113356","https://openalex.org/W2043155250","https://openalex.org/W2043296831","https://openalex.org/W2043583637","https://openalex.org/W2043736196","https://openalex.org/W2043990114","https://openalex.org/W2045413692","https://openalex.org/W2045513421","https://openalex.org/W2046093681","https://openalex.org/W2046878474","https://openalex.org/W2047304135","https://openalex.org/W2049063210","https://openalex.org/W2049158897","https://openalex.org/W2050963403","https://openalex.org/W2051381753","https://openalex.org/W2051878990","https://openalex.org/W2052871899","https://openalex.org/W2053355539","https://openalex.org/W2055029971","https://openalex.org/W2061239925","https://openalex.org/W2061602841","https://openalex.org/W2062800150","https://openalex.org/W2062929894","https://openalex.org/W2063223383","https://openalex.org/W2063461664","https://openalex.org/W2064954336","https://openalex.org/W2065280880","https://openalex.org/W2065642823","https://openalex.org/W2066073825","https://openalex.org/W2067219855","https://openalex.org/W2067656302","https://openalex.org/W2068195892","https://openalex.org/W2068552207","https://openalex.org/W2068708003","https://openalex.org/W2069385310","https://openalex.org/W2069997530","https://openalex.org/W2073053925","https://openalex.org/W2073795942","https://openalex.org/W2075957995","https://openalex.org/W2076653387","https://openalex.org/W2076726968","https://openalex.org/W2077563180","https://openalex.org/W2077905541","https://openalex.org/W2078446163","https://openalex.org/W2078884991","https://openalex.org/W2079097719","https://openalex.org/W2079596907","https://openalex.org/W2081414613","https://openalex.org/W2081591681","https://openalex.org/W2082174774","https://openalex.org/W2082469838","https://openalex.org/W2082957492","https://openalex.org/W2083319672","https://openalex.org/W2083532395","https://openalex.org/W2083721486","https://openalex.org/W2083857857","https://openalex.org/W2085567513","https://openalex.org/W2087510369","https://openalex.org/W2087646722","https://openalex.org/W2088146829","https://openalex.org/W2088800504","https://openalex.org/W2088828430","https://openalex.org/W2089904550","https://openalex.org/W2091122227","https://openalex.org/W2092493655","https://openalex.org/W2094459660","https://openalex.org/W2095562928","https://openalex.org/W2097057174","https://openalex.org/W2097518651","https://openalex.org/W2098393215","https://openalex.org/W2098838722","https://openalex.org/W2102318368","https://openalex.org/W2103452245","https://openalex.org/W2104811919","https://openalex.org/W2105741497","https://openalex.org/W2106746114","https://openalex.org/W2109474247","https://openalex.org/W2110443820","https://openalex.org/W2111815995","https://openalex.org/W2116581591","https://openalex.org/W2118498073","https://openalex.org/W2118766787","https://openalex.org/W2119143636","https://openalex.org/W2119668838","https://openalex.org/W2121427202","https://openalex.org/W2123886761","https://openalex.org/W2125768955","https://openalex.org/W2128763002","https://openalex.org/W2130006236","https://openalex.org/W2131508512","https://openalex.org/W2131702888","https://openalex.org/W2131884779","https://openalex.org/W2132386943","https://openalex.org/W2133647937","https://openalex.org/W2136027884","https://openalex.org/W2137737419","https://openalex.org/W2137769130","https://openalex.org/W2139240491","https://openalex.org/W2140453174","https://openalex.org/W2140725487","https://openalex.org/W2141594189","https://openalex.org/W2144011357","https://openalex.org/W2145091158","https://openalex.org/W2147091229","https://openalex.org/W2147474048","https://openalex.org/W2148132279","https://openalex.org/W2149117092","https://openalex.org/W2151742855","https://openalex.org/W2151954713","https://openalex.org/W2152176023","https://openalex.org/W2152403161","https://openalex.org/W2154164834","https://openalex.org/W2155268095","https://openalex.org/W2155742252","https://openalex.org/W2156248335","https://openalex.org/W2160888055","https://openalex.org/W2162207774","https://openalex.org/W2163022331","https://openalex.org/W2163983125","https://openalex.org/W2165744221","https://openalex.org/W2167042324","https://openalex.org/W2167559441","https://openalex.org/W2167801130","https://openalex.org/W2168585771","https://openalex.org/W2168911878","https://openalex.org/W2243301111","https://openalex.org/W2258955489","https://openalex.org/W2339204465","https://openalex.org/W2405787727","https://openalex.org/W2406170348","https://openalex.org/W2410160051","https://openalex.org/W2411984691","https://openalex.org/W2415472994","https://openalex.org/W2422062372","https://openalex.org/W2441916131","https://openalex.org/W2462810247","https://openalex.org/W2472856131","https://openalex.org/W2528179918","https://openalex.org/W2887334617","https://openalex.org/W3035477170","https://openalex.org/W4233887866"],"related_works":["https://openalex.org/W2788849479","https://openalex.org/W1971242940","https://openalex.org/W1985793603","https://openalex.org/W4410796765","https://openalex.org/W2004193374","https://openalex.org/W4312992032","https://openalex.org/W3114580799","https://openalex.org/W2046093681","https://openalex.org/W2114315564","https://openalex.org/W6998781530"],"abstract_inverted_index":{"Disinfection":[0],"by-products":[1],"(DBPs)":[2],"are":[3,158,360],"a":[4,55,61,174,192,195,229,244,250,264,273,330,387,412,430,466],"major":[5,113],"group":[6],"of":[7,43,57,64,74,83,111,172,190,263,266,279,290,293,371,414],"water":[8,51,118,144,260],"contaminants":[9],"and":[10,29,37,40,96,137,146,204,253,300,311,335,370,463],"their":[11],"role":[12],"in":[13,77,105,115,132,154,222,238,269,281,297,309,327,358,406,421,433],"causing":[14],"adverse":[15,19,26,93,102,454],"health":[16,27,86],"outcomes,":[17,21],"including":[18],"pregnancy":[20,94,103,455],"endocrine":[22],"disruption,":[23],"respiratory":[24],"related":[25,98,285],"outcomes":[28,87,95,104,211],"cancer":[30],"has":[31,53],"been":[32,54],"subject":[33],"to":[34,46,128,134,258,286,362,404,439,448,451],"extensive":[35,58,108],"epidemiological":[36],"toxicological":[38],"research":[39,76],"review.":[41],"Determination":[42],"safe":[44],"exposure":[45,181,240,288,403,438,461,485],"DBPs,":[47],"particularly":[48],"within":[49],"drinking":[50,117],"supplies,":[52],"topic":[56],"debate,":[59],"with":[60,89,176,186,194,215,314],"wide":[62],"range":[63],"acceptable":[65],"levels":[66,348],"set":[67],"across":[68],"the":[69,75,84,112,143,287,291,298,306,315,323,373,394,401,407,418,444,480],"industrialized":[70],"world.":[71],"The":[72],"focus":[73],"this":[78,227],"thesis":[79],"was":[80,119,125,149,182,234,256,283,338,353],"on":[81,225,386,458],"two":[82],"main":[85],"associated":[88,185,214],"DBP":[90,139,484],"exposure,":[91,409],"namely":[92],"asthma":[97],"symptoms.":[99],"To":[100],"assess":[101,129,259,452],"Perth,":[106],"an":[107,187,216,220,453],"classification":[109],"quantification":[110],"DBPs":[114,237,280],"Perth":[116,282,359],"conducted.":[120,351],"A":[121],"registrybased":[122],"prevalence":[123,324],"study":[124,255,325],"carried":[126],"out":[127],"birth":[130,178,202,320,336,343,422,434],"defects":[131],"relation":[133],"high,":[135],"medium":[136],"low":[138],"areas":[140,157],"(defined":[141,326],"by":[142],"sampling":[145],"analysis).":[147],"It":[148,352],"found":[150],"that":[151,355],"women":[152,268,295,357,460],"living":[153],"high":[155,239],"THM":[156,347],"22%":[159],"(odds":[160],"ratio":[161],"(OR)":[162],"1.22,":[163],"95%":[164],"confidence":[165],"interval":[166],"(95%":[167],"CI)":[168],"1.01-1.48)":[169],"more":[170,374],"likely":[171],"having":[173,191],"baby":[175,193],"any":[177],"defect.":[179],"High":[180],"also":[183,207,478],"strongly":[184],"increased":[188,199,217],"risk":[189,218,231],"cardiovascular":[196],"defect":[197],"(62%":[198],"risk).":[200],"Low":[201],"weight":[203,321,337,423,435],"prematurity":[205],"were":[206,212,349],"assessed;":[208],"however":[209],"these":[210],"not":[213,425,474],"through":[219],"increase":[221],"exposure.":[223],"Following":[224],"from":[226,322,398],"analysis,":[228],"population":[230,265,292],"assessment":[232],"model":[233,275,332,389,447],"developed":[235,450],"for":[236,276,319,333,342,379,393,400,469],"environments.":[241],"This":[242,442],"involved":[243,296],"three":[245],"step":[246],"process:":[247],"(i)":[248,310],"Firstly":[249],"questionnaire-based":[251],"validation":[252,299],"reliability":[254,301],"used":[257],"consumption":[261],"patterns":[262,289],"pregnant":[267,294,356,459],"Perth.":[270],"(ii)":[271],"Secondly":[272],"prediction":[274],"teratogenic":[277],"burden":[278],"developed,":[284],"study.":[302],"(iii)":[303],"Finally,":[304],"combining":[305],"information":[307],"collected":[308],"(ii),":[312],"along":[313],"regression":[316],"slope":[317],"estimates":[318],"Section":[328],"2.2.1),":[329],"dose-response":[331,388],"THMs":[334],"developed.":[339],"Predictive":[340],"simulations":[341],"weights":[344],"at":[345],"given":[346],"then":[350],"estimated":[354],"exposed":[361],"between":[363,380],"0.3":[364],"\u2013":[365,382],"4.10":[366],"\u03bcg/day":[367],"ingested":[368],"TTHM,":[369],"this,":[372],"toxic":[375],"brominated":[376],"forms":[377],"accounted":[378],"0.27":[381],"3.69":[383],"\u03bcg/day.":[384],"Based":[385],"used,":[390],"birthweights":[391],"calculated":[392],"\u2018hypothetical\u2019":[395],"exposures":[396,472],"ranged":[397],"3403.2g":[399],"highest":[402],"3503.5g":[405],"lowest":[408],"which":[410],"is":[411,424,428,443,486],"difference":[413],"over":[415],"100g.":[416],"Although":[417],"resulting":[419],"reduction":[420,432],"extreme,":[426],"there":[427],"still":[429],"significant":[431],"present":[436],"as":[437],"TTHMs":[440],"increases.":[441],"first":[445],"doseresponse":[446],"be":[449,465],"outcome":[456],"based":[457],"data,":[462],"will":[464],"useful":[467],"tool":[468],"assessing":[470],"varying":[471],"throughout":[473,479],"only":[475],"Australia":[476],"but":[477],"industrialised":[481],"world,":[482],"where":[483],"highly":[487],"prevalent.":[488]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-03-16T00:00:00"}