{"id":"https://openalex.org/W2592882031","doi":null,"title":"REVIEW PAPER The genetics of melanoma","display_name":"REVIEW PAPER The genetics of melanoma","publication_year":2006,"publication_date":"2006-02-24","ids":{"openalex":"https://openalex.org/W2592882031","mag":"2592882031"},"language":"pl","primary_location":{"id":"pmh:oai:ruj.uj.edu.pl:item/157239","doi":null,"is_oa":true,"landing_page_url":"https://www.termedia.pl/REVIEW-PAPER-The-genetics-of-melanoma,7,5605,0,1.html","pdf_url":"https://ruj.uj.edu.pl/xmlui/handle/item/157239","source":{"id":"https://openalex.org/S4306401249","display_name":"Jagiellonian University Repository (Jagiellonian University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I126596746","host_organization_name":"Jagiellonian University","host_organization_lineage":["https://openalex.org/I126596746"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://ruj.uj.edu.pl/xmlui/handle/item/157239","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077094834","display_name":"Urszula Brudnik","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Urszula Brudnik","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107871529","display_name":"Anna Wojas\u2010Pelc","orcid":"https://orcid.org/0000-0002-5702-4746","observed_orcids":["https://orcid.org/0000-0002-5702-4746"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anna Wojas\u2010Pelc","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5029929961","display_name":"Wojciech Branicki","orcid":"https://orcid.org/0000-0002-7412-5733","observed_orcids":["https://orcid.org/0000-0002-7412-5733"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wojciech Branicki","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7412-5733","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.26526808,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"23","issue":"1","first_page":"21","last_page":"25"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11533","display_name":"Melanoma and MAPK Pathways","score":0.8939999938011169,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11533","display_name":"Melanoma and MAPK Pathways","score":0.8939999938011169,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10392","display_name":"Cutaneous Melanoma Detection and Management","score":0.0697999969124794,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11144","display_name":"melanin and skin pigmentation","score":0.01549999974668026,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/melanoma","display_name":"melanoma","score":0.8790000081062317},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.734000027179718},{"id":"https://openalex.org/keywords/cdkn2a","display_name":"CDKN2A","score":0.8130000233650208},{"id":"https://openalex.org/keywords/cdk4","display_name":"CDK4","score":0.9959999918937683},{"id":"https://openalex.org/keywords/mc1r","display_name":"MC1R","score":0.8939999938011169},{"id":"https://openalex.org/keywords/pten","display_name":"PTEN","score":0.9990000128746033},{"id":"https://openalex.org/keywords/braf","display_name":"BRAF","score":0.9929999709129333},{"id":"https://openalex.org/keywords/nras","display_name":"NRAS","score":1.0},{"id":"https://openalex.org/keywords/epistasis","display_name":"epistasis","score":0.8109999895095825},{"id":"https://openalex.org/keywords/gene-environment-interaction","display_name":"gene-environment interaction","score":0.9850000143051147},{"id":"https://openalex.org/keywords/cell-cycle-genes","display_name":"cell cycle genes","score":0.8600000143051147},{"id":"https://openalex.org/keywords/cancer-risk","display_name":"cancer risk","score":0.5249999761581421}],"concepts":[{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4132373332977295},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3853771388530731},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3713850975036621},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3613293468952179}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:ruj.uj.edu.pl:item/157239","doi":null,"is_oa":true,"landing_page_url":"https://www.termedia.pl/REVIEW-PAPER-The-genetics-of-melanoma,7,5605,0,1.html","pdf_url":"https://ruj.uj.edu.pl/xmlui/handle/item/157239","source":{"id":"https://openalex.org/S4306401249","display_name":"Jagiellonian University Repository (Jagiellonian University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I126596746","host_organization_name":"Jagiellonian University","host_organization_lineage":["https://openalex.org/I126596746"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2592882031","doi":null,"is_oa":false,"landing_page_url":"https://www.termedia.pl/Journal/-7/pdf-5605-1?filename=Genetyczne.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S119393630","display_name":"Advances in Dermatology and Allergology","issn_l":"0860-6218","issn":["0860-6218","1642-395X","2299-0046"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320332","host_organization_name":"Termedia Publishing House","host_organization_lineage":["https://openalex.org/P4310320332"],"host_organization_lineage_names":["Termedia Publishing House"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Advances in Dermatology and Allergology/Post\u0119py Dermatologii i Alergologii","raw_type":null}],"best_oa_location":{"id":"pmh:oai:ruj.uj.edu.pl:item/157239","doi":null,"is_oa":true,"landing_page_url":"https://www.termedia.pl/REVIEW-PAPER-The-genetics-of-melanoma,7,5605,0,1.html","pdf_url":"https://ruj.uj.edu.pl/xmlui/handle/item/157239","source":{"id":"https://openalex.org/S4306401249","display_name":"Jagiellonian University Repository (Jagiellonian University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I126596746","host_organization_name":"Jagiellonian University","host_organization_lineage":["https://openalex.org/I126596746"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2592882031.pdf","grobid_xml":"https://content.openalex.org/works/W2592882031.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W6960019538","https://openalex.org/W3184168834","https://openalex.org/W7074615584","https://openalex.org/W4292804922","https://openalex.org/W2411014696","https://openalex.org/W2408092185","https://openalex.org/W2460485540","https://openalex.org/W6959956692","https://openalex.org/W2603199878","https://openalex.org/W4396796476"],"abstract_inverted_index":{"Melanoma":[0],"is":[1],"an":[2],"important":[3],"public":[4],"health":[5],"issue":[6],"and":[7,19,52,61,80],"research":[8],"strategies":[9],"are":[10,73],"trying":[11],"to":[12,47,53,86],"elucidate":[13],"the":[14,30,55,58],"relative":[15],"contribution":[16],"of":[17,27,32,57],"genes":[18,35,51],"environmental":[20,62,82],"factors":[21,29],"in":[22],"its":[23],"causation.":[24],"In":[25],"terms":[26],"genetic":[28,60],"discovery":[31],"cell":[33],"cycle":[34],"-CDKN2a,":[36],"CDK4":[37],"-":[38],"has":[39],"been":[40],"a":[41],"great":[42],"advance.":[43],"Current":[44],"studies":[45,84],"aim":[46,85],"identify":[48],"other":[49],"susceptibility":[50],"determine":[54],"interactions":[56,83],"various":[59],"factors.":[63],"Among":[64],"them,":[65],"MC1R":[66],"(Melanocortin-1":[67],"receptor":[68],"gene),":[69],"PTEN,":[70],"BRAF,":[71],"NRAS":[72],"being":[74],"analysed":[75],"more":[76],"closely.":[77],"Epistatic":[78],"(gene-gene)":[79],"gene":[81],"recognize":[87],"individuals":[88],"at":[89],"high":[90],"risk.":[91]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2017-03-16T00:00:00"}