{"id":"https://openalex.org/W2592811083","doi":"https://doi.org/10.1080/03601238209372316","title":"Mammalian toxicity of technical X\u2010factor1I. An acute oral study","display_name":"Mammalian toxicity of technical X\u2010factor1I. An acute oral study","publication_year":1982,"publication_date":"1982-01-01","ids":{"openalex":"https://openalex.org/W2592811083","doi":"https://doi.org/10.1080/03601238209372316","mag":"2592811083","pmid":"https://pubmed.ncbi.nlm.nih.gov/6178773"},"language":"en","primary_location":{"id":"doi:10.1080/03601238209372316","doi":"https://doi.org/10.1080/03601238209372316","is_oa":false,"landing_page_url":"https://doi.org/10.1080/03601238209372316","pdf_url":null,"source":{"id":"https://openalex.org/S175163693","display_name":"Journal of Environmental Science and Health Part B","issn_l":"0360-1234","issn":["0360-1234","1532-4109"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Environmental Science and Health, Part B","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007922174","display_name":"M. K. Krishnakumari","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150037166","display_name":"Central Food Technological Research Institute","ror":"https://ror.org/01d7fn555","country_code":"IN","type":"facility","lineage":["https://openalex.org/I150037166","https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"M.K. Krishnakumari","raw_affiliation_strings":["Toxicology Unit, Infestation Control & Pesticides, Central Food Technological Research Institute, Mysore, 570 013, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Toxicology Unit, Infestation Control & Pesticides, Central Food Technological Research Institute, Mysore, 570 013, India","institution_ids":["https://openalex.org/I150037166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108084628","display_name":"Muralidhara .","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150037166","display_name":"Central Food Technological Research Institute","ror":"https://ror.org/01d7fn555","country_code":"IN","type":"facility","lineage":["https://openalex.org/I150037166","https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Muralidhara","raw_affiliation_strings":["Toxicology Unit, Infestation Control & Pesticides, Central Food Technological Research Institute, Mysore, 570 013, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Toxicology Unit, Infestation Control & Pesticides, Central Food Technological Research Institute, Mysore, 570 013, India","institution_ids":["https://openalex.org/I150037166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111896000","display_name":"S. Muralidhara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150037166","display_name":"Central Food Technological Research Institute","ror":"https://ror.org/01d7fn555","country_code":"IN","type":"facility","lineage":["https://openalex.org/I150037166","https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"S. Muralidhara","raw_affiliation_strings":["Toxicology Unit, Infestation Control & Pesticides, Central Food Technological Research Institute, Mysore, 570 013, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Toxicology Unit, Infestation Control & Pesticides, Central Food Technological Research Institute, Mysore, 570 013, India","institution_ids":["https://openalex.org/I150037166"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059186114","display_name":"S. K. Majumder","orcid":"https://orcid.org/0000-0001-7900-9785","observed_orcids":["https://orcid.org/0000-0001-7900-9785"]},"institutions":[{"id":"https://openalex.org/I150037166","display_name":"Central Food Technological Research Institute","ror":"https://ror.org/01d7fn555","country_code":"IN","type":"facility","lineage":["https://openalex.org/I150037166","https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"S.K. Majumder","raw_affiliation_strings":["Toxicology Unit, Infestation Control & Pesticides, Central Food Technological Research Institute, Mysore, 570 013, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Toxicology Unit, Infestation Control & Pesticides, Central Food Technological Research Institute, Mysore, 570 013, India","institution_ids":["https://openalex.org/I150037166"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I150037166"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.3313687,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"17","issue":"3","first_page":"241","last_page":"252"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10875","display_name":"Pesticide Exposure and Toxicity","score":0.9423999786376953,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10875","display_name":"Pesticide Exposure and Toxicity","score":0.9423999786376953,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10122","display_name":"Toxic Organic Pollutants Impact","score":0.025299999862909317,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11180","display_name":"Pesticide and Herbicide Environmental Studies","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lindane","display_name":"lindane","score":0.8360000252723694},{"id":"https://openalex.org/keywords/acute-oral-toxicity","display_name":"acute oral toxicity","score":0.8330000042915344},{"id":"https://openalex.org/keywords/ld50","display_name":"LD50","score":0.8349999785423279},{"id":"https://openalex.org/keywords/central-nervous-system-depression","display_name":"central nervous system depression","score":0.9810000061988831},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.48399999737739563}],"concepts":[{"id":"https://openalex.org/C116263406","wikidata":"https://www.wikidata.org/wiki/Q3299024","display_name":"Acute toxicity","level":3,"score":0.7924816608428955},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.7318693399429321},{"id":"https://openalex.org/C2777383412","wikidata":"https://www.wikidata.org/wiki/Q4770891","display_name":"Antagonism","level":3,"score":0.7079227566719055},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5105160474777222},{"id":"https://openalex.org/C2780120631","wikidata":"https://www.wikidata.org/wiki/Q282003","display_name":"Lindane","level":3,"score":0.45772063732147217},{"id":"https://openalex.org/C2777056448","wikidata":"https://www.wikidata.org/wiki/Q285166","display_name":"Oral administration","level":2,"score":0.4398617744445801},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.4325031638145447},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3961776793003082},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.3812461197376251},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3784435987472534},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34902423620224},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.32685303688049316},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30199554562568665},{"id":"https://openalex.org/C161176658","wikidata":"https://www.wikidata.org/wiki/Q131656","display_name":"Pesticide","level":2,"score":0.24282875657081604},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.10671257972717285},{"id":"https://openalex.org/C6557445","wikidata":"https://www.wikidata.org/wiki/Q173113","display_name":"Agronomy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001556","descriptor_name":"Hexachlorocyclohexane","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004435","descriptor_name":"Eating","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007928","descriptor_name":"Lethal Dose 50","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009929","descriptor_name":"Organ Size","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1080/03601238209372316","doi":"https://doi.org/10.1080/03601238209372316","is_oa":false,"landing_page_url":"https://doi.org/10.1080/03601238209372316","pdf_url":null,"source":{"id":"https://openalex.org/S175163693","display_name":"Journal of Environmental Science and Health Part B","issn_l":"0360-1234","issn":["0360-1234","1532-4109"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Environmental Science and Health, Part B","raw_type":"journal-article"},{"id":"pmid:6178773","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6178773","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes","raw_type":"Journal Article"},{"id":"pmh:oai:ir.cftri.com:4589","doi":null,"is_oa":false,"landing_page_url":"http://ir.cftri.com/4589/1/J.%20ENVIRON.%20SCI.%20HEALTH%2C%20B17%283%29%2C%20241-252%20%281982%29.pdf","pdf_url":"http://ir.cftri.com/4589/1/J.%20ENVIRON.%20SCI.%20HEALTH%2C%20B17%283%29%2C%20241-252%20%281982%29.pdf","source":{"id":"https://openalex.org/S4406922581","display_name":"CFTRI Institutional Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W403103530","https://openalex.org/W1965816959","https://openalex.org/W1983297439","https://openalex.org/W2074421326","https://openalex.org/W2169770997","https://openalex.org/W2336261656","https://openalex.org/W4291254048"],"related_works":["https://openalex.org/W2080834846","https://openalex.org/W2291807140","https://openalex.org/W2321228030","https://openalex.org/W7074066890","https://openalex.org/W2394742123","https://openalex.org/W2408087309","https://openalex.org/W2590989244","https://openalex.org/W2316173481","https://openalex.org/W2290463730","https://openalex.org/W2346711869"],"abstract_inverted_index":{"Intragastric":[0],"administration":[1],"of":[2,5,16,28,41,62,79,89],"acute":[3,59,76],"doses":[4],"Technical":[6],"X-factor":[7,42,80],"(beta-isomer":[8],"free":[9],"BHC,":[10],"a":[11,86],"byproduct":[12],"obtained":[13],"during":[14],"separation":[15],"Lindane":[17],"from":[18],"Tech.":[19,68],"BHC)":[20],"carried":[21],"in":[22,33,94,97],"peanut":[23],"oil":[24],"elicited":[25],"typical":[26],"signs":[27],"central":[29],"nervous":[30],"system":[31],"depression":[32],"adult":[34],"rats.":[35],"The":[36],"computed":[37],"oral":[38],"LD50":[39],"values":[40],"were":[43],"4174":[44],"and":[45,52],"5673":[46],"mg/kg.":[47],"body":[48],"weight":[49],"for":[50],"male":[51],"female":[53],"rats":[54],"respectively":[55],"indicating":[56],"that":[57,73],"its":[58],"toxicity":[60,78],"was":[61],"relatively":[63],"low":[64,75],"order":[65],"compared":[66],"to":[67,85],"BHC.":[69],"It":[70],"is":[71],"suggested":[72],"the":[74,90,100],"mammalian":[77],"could":[81],"possibly":[82],"be":[83],"due":[84],"direct":[87],"antagonism":[88],"delta":[91],"isomer":[92],"(present":[93],"larger":[95],"proportion":[96],"X-factor)":[98],"with":[99],"gamma":[101],"isomer.":[102]},"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2017-03-16T00:00:00"}