{"id":"https://openalex.org/W2592698726","doi":"https://doi.org/10.1016/j.mce.2017.03.004","title":"Zebrafish \u2013 An emerging model to explore thyroid hormone transporters and psychomotor retardation","display_name":"Zebrafish \u2013 An emerging model to explore thyroid hormone transporters and psychomotor retardation","publication_year":2017,"publication_date":"2017-03-06","ids":{"openalex":"https://openalex.org/W2592698726","doi":"https://doi.org/10.1016/j.mce.2017.03.004","mag":"2592698726","pmid":"https://pubmed.ncbi.nlm.nih.gov/28274736"},"language":"en","primary_location":{"id":"doi:10.1016/j.mce.2017.03.004","doi":"https://doi.org/10.1016/j.mce.2017.03.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.mce.2017.03.004","pdf_url":null,"source":{"id":"https://openalex.org/S191044671","display_name":"Molecular and Cellular Endocrinology","issn_l":"0303-7207","issn":["0303-7207","1872-8057"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Endocrinology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056346051","display_name":"David Zada","orcid":"https://orcid.org/0000-0002-5064-247X","observed_orcids":["https://orcid.org/0000-0002-5064-247X"]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"David Zada","raw_affiliation_strings":["The Faculty of Life Sciences and the Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat-Gan 5290002, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Faculty of Life Sciences and the Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat-Gan 5290002, Israel","institution_ids":["https://openalex.org/I13955877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050896231","display_name":"Einat Blitz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Einat Blitz","raw_affiliation_strings":["The Faculty of Life Sciences and the Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat-Gan 5290002, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Faculty of Life Sciences and the Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat-Gan 5290002, Israel","institution_ids":["https://openalex.org/I13955877"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027650124","display_name":"Lior Appelbaum","orcid":"https://orcid.org/0000-0002-9248-5919","observed_orcids":["https://orcid.org/0000-0002-9248-5919"]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Lior Appelbaum","raw_affiliation_strings":["The Faculty of Life Sciences and the Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat-Gan 5290002, Israel. Electronic address: lior.appelbaum@biu.ac.il","The Faculty of Life Sciences and the Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat-Gan 5290002, Israel"],"raw_orcid":"https://orcid.org/0000-0002-9248-5919","affiliations":[{"raw_affiliation_string":"The Faculty of Life Sciences and the Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat-Gan 5290002, Israel. Electronic address: lior.appelbaum@biu.ac.il","institution_ids":["https://openalex.org/I13955877"]},{"raw_affiliation_string":"The Faculty of Life Sciences and the Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat-Gan 5290002, Israel","institution_ids":["https://openalex.org/I13955877"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5027650124"],"corresponding_institution_ids":["https://openalex.org/I13955877"],"apc_list":{"value":3510,"currency":"USD","value_usd":3510},"apc_paid":null,"fwci":2.1883,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.86116529,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"459","issue":null,"first_page":"53","last_page":"58"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11685","display_name":"Zebrafish Biomedical Research Applications","score":0.4860999882221222,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11685","display_name":"Zebrafish Biomedical Research Applications","score":0.4860999882221222,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.3400999903678894,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.059300001710653305,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thyroid-hormone-transporters","display_name":"thyroid hormone transporters","score":0.9520000219345093},{"id":"https://openalex.org/keywords/zebrafish","display_name":"zebrafish","score":0.8040000200271606},{"id":"https://openalex.org/keywords/psychomotor-retardation","display_name":"psychomotor retardation","score":0.9229999780654907},{"id":"https://openalex.org/keywords/allan-herndon-dudley-syndrome","display_name":"Allan-Herndon-Dudley syndrome","score":0.9879999756813049},{"id":"https://openalex.org/keywords/mct8","display_name":"MCT8","score":0.8709999918937683},{"id":"https://openalex.org/keywords/slc16a2","display_name":"SLC16A2","score":0.9300000071525574},{"id":"https://openalex.org/keywords/mct10","display_name":"MCT10","score":0.9869999885559082},{"id":"https://openalex.org/keywords/oatp1c1","display_name":"OATP1C1","score":0.9959999918937683},{"id":"https://openalex.org/keywords/x-linked-disorders","display_name":"X-linked disorders","score":0.6779999732971191},{"id":"https://openalex.org/keywords/neuroendocrinology","display_name":"neuroendocrinology","score":0.7620000243186951},{"id":"https://openalex.org/keywords/translational-research","display_name":"translational research","score":0.546999990940094}],"concepts":[{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.8738871812820435},{"id":"https://openalex.org/C2781217356","wikidata":"https://www.wikidata.org/wiki/Q83426191","display_name":"Monocarboxylate transporter","level":4,"score":0.8066725730895996},{"id":"https://openalex.org/C149011108","wikidata":"https://www.wikidata.org/wiki/Q652985","display_name":"Transporter","level":3,"score":0.6021851897239685},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.5642492771148682},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5282173156738281},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.5186423659324646},{"id":"https://openalex.org/C2776678969","wikidata":"https://www.wikidata.org/wiki/Q28209167","display_name":"Organic anion-transporting polypeptide","level":4,"score":0.43912482261657715},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.41854697465896606},{"id":"https://openalex.org/C2776202747","wikidata":"https://www.wikidata.org/wiki/Q3064951","display_name":"Psychomotor retardation","level":3,"score":0.4133807420730591},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3610410690307617},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.32588332891464233},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.29307621717453003},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2354428470134735},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.23033800721168518},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007814","descriptor_name":"Larva","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007814","descriptor_name":"Larva","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D007814","descriptor_name":"Larva","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009123","descriptor_name":"Muscle Hypotonia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009123","descriptor_name":"Muscle Hypotonia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009123","descriptor_name":"Muscle Hypotonia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009133","descriptor_name":"Muscular Atrophy","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009133","descriptor_name":"Muscular Atrophy","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009133","descriptor_name":"Muscular Atrophy","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013963","descriptor_name":"Thyroid Hormones","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D013963","descriptor_name":"Thyroid Hormones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D027361","descriptor_name":"Organic Anion Transporters","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D027361","descriptor_name":"Organic Anion Transporters","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D027501","descriptor_name":"Monocarboxylic Acid Transporters","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D027501","descriptor_name":"Monocarboxylic Acid Transporters","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D038901","descriptor_name":"X-Linked Intellectual Disability","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D038901","descriptor_name":"X-Linked Intellectual Disability","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D038901","descriptor_name":"X-Linked Intellectual Disability","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D055786","descriptor_name":"Gene Knockout Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.mce.2017.03.004","doi":"https://doi.org/10.1016/j.mce.2017.03.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.mce.2017.03.004","pdf_url":null,"source":{"id":"https://openalex.org/S191044671","display_name":"Molecular and Cellular Endocrinology","issn_l":"0303-7207","issn":["0303-7207","1872-8057"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Endocrinology","raw_type":"journal-article"},{"id":"pmid:28274736","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28274736","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and cellular endocrinology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1717812015","display_name":null,"funder_award_id":"I-1314-418.13/2015","funder_id":"https://openalex.org/F4320320947","funder_display_name":"German-Israeli Foundation for Scientific Research and Development"},{"id":"https://openalex.org/G4202349479","display_name":null,"funder_award_id":"GIF, I-1314-418.13/2015","funder_id":"https://openalex.org/F4320320947","funder_display_name":"German-Israeli Foundation for Scientific Research and Development"},{"id":"https://openalex.org/G8067993001","display_name":null,"funder_award_id":"3-10861","funder_id":"https://openalex.org/F4320317617","funder_display_name":"E-Rare"}],"funders":[{"id":"https://openalex.org/F4320317617","display_name":"E-Rare","ror":null},{"id":"https://openalex.org/F4320320889","display_name":"Fondation J\u00e9r\u00f4me Lejeune","ror":"https://ror.org/03js3tm40"},{"id":"https://openalex.org/F4320320947","display_name":"German-Israeli Foundation for Scientific Research and Development","ror":"https://ror.org/00tntzp09"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W1551156528","https://openalex.org/W1615535881","https://openalex.org/W1952875124","https://openalex.org/W1963976116","https://openalex.org/W1969128125","https://openalex.org/W1970177972","https://openalex.org/W1971978102","https://openalex.org/W1975345061","https://openalex.org/W1977631945","https://openalex.org/W1991454487","https://openalex.org/W1992268803","https://openalex.org/W1999007774","https://openalex.org/W1999728382","https://openalex.org/W2013988137","https://openalex.org/W2017632004","https://openalex.org/W2022349101","https://openalex.org/W2025894647","https://openalex.org/W2028422261","https://openalex.org/W2028682724","https://openalex.org/W2033553696","https://openalex.org/W2033638549","https://openalex.org/W2038696712","https://openalex.org/W2043055866","https://openalex.org/W2046037386","https://openalex.org/W2053328855","https://openalex.org/W2061298688","https://openalex.org/W2062347722","https://openalex.org/W2063518508","https://openalex.org/W2076995039","https://openalex.org/W2083722030","https://openalex.org/W2089467141","https://openalex.org/W2102611661","https://openalex.org/W2110539117","https://openalex.org/W2119888891","https://openalex.org/W2123696673","https://openalex.org/W2127859037","https://openalex.org/W2133877174","https://openalex.org/W2142908518","https://openalex.org/W2147843272","https://openalex.org/W2149476005","https://openalex.org/W2156416721","https://openalex.org/W2157742187","https://openalex.org/W2160488497","https://openalex.org/W2163861951","https://openalex.org/W2167486844","https://openalex.org/W2201239534","https://openalex.org/W2293184999","https://openalex.org/W2547136347","https://openalex.org/W6653736628"],"related_works":["https://openalex.org/W2078333270","https://openalex.org/W2617455138","https://openalex.org/W2149476005","https://openalex.org/W2111575083","https://openalex.org/W2133877174","https://openalex.org/W7213551832","https://openalex.org/W4246705380","https://openalex.org/W1486716577","https://openalex.org/W2046152275","https://openalex.org/W2011366445"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3}],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2017-03-16T00:00:00"}