{"id":"https://openalex.org/W2592351228","doi":null,"title":"Mapping and functional characterisation of the Atlantic salmon genome and its regulation of pathogen response","display_name":"Mapping and functional characterisation of the Atlantic salmon genome and its regulation of pathogen response","publication_year":2015,"publication_date":"2015-11-27","ids":{"openalex":"https://openalex.org/W2592351228","mag":"2592351228"},"language":"en","primary_location":{"id":"pmh:oai:era.ed.ac.uk:1842/19518","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1842/19518","pdf_url":null,"source":{"id":"https://openalex.org/S7407055182","display_name":"ERA","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis or Dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/1842/19518","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079245386","display_name":"Serap Gonen","orcid":"https://orcid.org/0000-0002-3937-6473","observed_orcids":["https://orcid.org/0000-0002-3937-6473"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Serap Gonen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3937-6473","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5079245386"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.8076000213623047,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.8076000213623047,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.08829999715089798,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.0723000019788742,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atlantic-salmon","display_name":"Atlantic salmon","score":0.9929999709129333},{"id":"https://openalex.org/keywords/genome-mapping","display_name":"genome mapping","score":0.593999981880188},{"id":"https://openalex.org/keywords/snp-linkage-map","display_name":"SNP linkage map","score":0.9729999899864197},{"id":"https://openalex.org/keywords/radseq","display_name":"RADseq","score":0.7730000019073486},{"id":"https://openalex.org/keywords/pathogen-resistance","display_name":"pathogen resistance","score":0.5979999899864197},{"id":"https://openalex.org/keywords/host-pathogen-interaction","display_name":"host-pathogen interaction","score":0.753000020980835},{"id":"https://openalex.org/keywords/homeology","display_name":"homeology","score":0.703000009059906},{"id":"https://openalex.org/keywords/sex-specific-recombination","display_name":"sex-specific recombination","score":0.5410000085830688},{"id":"https://openalex.org/keywords/chiasmata","display_name":"chiasmata","score":0.609000027179718},{"id":"https://openalex.org/keywords/genomic-resources","display_name":"genomic resources","score":0.4020000100135803},{"id":"https://openalex.org/keywords/marker-assisted-selection","display_name":"marker-assisted selection","score":0.7059999704360962},{"id":"https://openalex.org/keywords/genomic-selection","display_name":"genomic selection","score":0.7710000276565552},{"id":"https://openalex.org/keywords/disease-resistance-breeding","display_name":"disease resistance breeding","score":0.5490000247955322}],"concepts":[{"id":"https://openalex.org/C2776460866","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogen","level":2,"score":0.5330468416213989},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5308393239974976},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5300329327583313},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4983663558959961},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.39069491624832153},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.35441434383392334},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3358860909938812},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.328630656003952},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.19231721758842468},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.16864433884620667}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:era.ed.ac.uk:1842/19518","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1842/19518","pdf_url":null,"source":{"id":"https://openalex.org/S7407055182","display_name":"ERA","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis or Dissertation"},{"id":"mag:2592351228","doi":null,"is_oa":false,"landing_page_url":"https://era.ed.ac.uk/handle/1842/19518","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:era.ed.ac.uk:1842/19518","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1842/19518","pdf_url":null,"source":{"id":"https://openalex.org/S7407055182","display_name":"ERA","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis or Dissertation"},"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.5666999816894531,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":332,"referenced_works":["https://openalex.org/W117961098","https://openalex.org/W119094524","https://openalex.org/W189171288","https://openalex.org/W631111161","https://openalex.org/W1481593413","https://openalex.org/W1482490553","https://openalex.org/W1489091024","https://openalex.org/W1505607253","https://openalex.org/W1526776209","https://openalex.org/W1531477187","https://openalex.org/W1587558271","https://openalex.org/W1596570748","https://openalex.org/W1605298882","https://openalex.org/W1689286279","https://openalex.org/W1806977764","https://openalex.org/W1807892535","https://openalex.org/W1830332211","https://openalex.org/W1843399746","https://openalex.org/W1877499567","https://openalex.org/W1884727077","https://openalex.org/W1901818114","https://openalex.org/W1932304146","https://openalex.org/W1945278980","https://openalex.org/W1949327024","https://openalex.org/W1950144341","https://openalex.org/W1965462508","https://openalex.org/W1965837217","https://openalex.org/W1965980737","https://openalex.org/W1966649436","https://openalex.org/W1966794959","https://openalex.org/W1968423560","https://openalex.org/W1968566330","https://openalex.org/W1968798344","https://openalex.org/W1969200465","https://openalex.org/W1969848743","https://openalex.org/W1970873644","https://openalex.org/W1972669210","https://openalex.org/W1975048284","https://openalex.org/W1975711633","https://openalex.org/W1975721554","https://openalex.org/W1977104259","https://openalex.org/W1977358834","https://openalex.org/W1977670849","https://openalex.org/W1980818742","https://openalex.org/W1982476312","https://openalex.org/W1982737915","https://openalex.org/W1985490733","https://openalex.org/W1986002459","https://openalex.org/W1986223292","https://openalex.org/W1987459045","https://openalex.org/W1987502745","https://openalex.org/W1989261348","https://openalex.org/W1989670827","https://openalex.org/W1990566629","https://openalex.org/W1990771642","https://openalex.org/W1990956288","https://openalex.org/W1993523938","https://openalex.org/W1993835751","https://openalex.org/W1995456582","https://openalex.org/W1995972977","https://openalex.org/W1997030658","https://openalex.org/W1997514729","https://openalex.org/W1999068621","https://openalex.org/W1999652349","https://openalex.org/W1999673315","https://openalex.org/W2000574277","https://openalex.org/W2000899135","https://openalex.org/W2001112166","https://openalex.org/W2001265061","https://openalex.org/W2002198069","https://openalex.org/W2002259094","https://openalex.org/W2002679394","https://openalex.org/W2004803944","https://openalex.org/W2005228725","https://openalex.org/W2005319444","https://openalex.org/W2006289002","https://openalex.org/W2006777514","https://openalex.org/W2007035318","https://openalex.org/W2008947392","https://openalex.org/W2009867049","https://openalex.org/W2011882057","https://openalex.org/W2012089313","https://openalex.org/W2012828872","https://openalex.org/W2013741791","https://openalex.org/W2014097855","https://openalex.org/W2014485546","https://openalex.org/W2015602829","https://openalex.org/W2016854012","https://openalex.org/W2017920360","https://openalex.org/W2017952818","https://openalex.org/W2018938785","https://openalex.org/W2021868759","https://openalex.org/W2022551231","https://openalex.org/W2023111451","https://openalex.org/W2023267128","https://openalex.org/W2024620417","https://openalex.org/W2025803511","https://openalex.org/W2026122678","https://openalex.org/W2026225729","https://openalex.org/W2026814125","https://openalex.org/W2027868754","https://openalex.org/W2029310937","https://openalex.org/W2029634564","https://openalex.org/W2033124377","https://openalex.org/W2034499270","https://openalex.org/W2035344810","https://openalex.org/W2037001414","https://openalex.org/W2038175202","https://openalex.org/W2038574100","https://openalex.org/W2039140268","https://openalex.org/W2040044941","https://openalex.org/W2040060570","https://openalex.org/W2041892467","https://openalex.org/W2043124872","https://openalex.org/W2044812873","https://openalex.org/W2045356594","https://openalex.org/W2046244154","https://openalex.org/W2048587645","https://openalex.org/W2048701699","https://openalex.org/W2050811270","https://openalex.org/W2051690406","https://openalex.org/W2051745208","https://openalex.org/W2052647803","https://openalex.org/W2054163738","https://openalex.org/W2055666215","https://openalex.org/W2055862922","https://openalex.org/W2056629326","https://openalex.org/W2058623575","https://openalex.org/W2058695412","https://openalex.org/W2058949503","https://openalex.org/W2059258858","https://openalex.org/W2059655994","https://openalex.org/W2059826994","https://openalex.org/W2059959904","https://openalex.org/W2060287868","https://openalex.org/W2061379160","https://openalex.org/W2061602742","https://openalex.org/W2061680286","https://openalex.org/W2062079659","https://openalex.org/W2062573923","https://openalex.org/W2062980622","https://openalex.org/W2063139657","https://openalex.org/W2064758465","https://openalex.org/W2065572944","https://openalex.org/W2065682672","https://openalex.org/W2066121149","https://openalex.org/W2067056720","https://openalex.org/W2069853795","https://openalex.org/W2071002343","https://openalex.org/W2071290870","https://openalex.org/W2071764217","https://openalex.org/W2072228267","https://openalex.org/W2072318743","https://openalex.org/W2072730267","https://openalex.org/W2073750325","https://openalex.org/W2074442724","https://openalex.org/W2074798811","https://openalex.org/W2074905529","https://openalex.org/W2076104377","https://openalex.org/W2077500768","https://openalex.org/W2077797235","https://openalex.org/W2078684082","https://openalex.org/W2080690656","https://openalex.org/W2081490133","https://openalex.org/W2081778808","https://openalex.org/W2082256196","https://openalex.org/W2083763658","https://openalex.org/W2084923853","https://openalex.org/W2085006244","https://openalex.org/W2085315239","https://openalex.org/W2085405726","https://openalex.org/W2085982890","https://openalex.org/W2086850502","https://openalex.org/W2087649816","https://openalex.org/W2088482084","https://openalex.org/W2088632182","https://openalex.org/W2089106709","https://openalex.org/W2089415411","https://openalex.org/W2092083583","https://openalex.org/W2095009534","https://openalex.org/W2095297220","https://openalex.org/W2095328383","https://openalex.org/W2095816222","https://openalex.org/W2095882149","https://openalex.org/W2096260517","https://openalex.org/W2097072668","https://openalex.org/W2097121305","https://openalex.org/W2097735274","https://openalex.org/W2097929532","https://openalex.org/W2098371528","https://openalex.org/W2099128165","https://openalex.org/W2099321785","https://openalex.org/W2099401758","https://openalex.org/W2099630697","https://openalex.org/W2100057436","https://openalex.org/W2100835617","https://openalex.org/W2101143553","https://openalex.org/W2101752958","https://openalex.org/W2102163928","https://openalex.org/W2102312968","https://openalex.org/W2102851297","https://openalex.org/W2103338565","https://openalex.org/W2104663888","https://openalex.org/W2105501854","https://openalex.org/W2106265043","https://openalex.org/W2106978325","https://openalex.org/W2107248582","https://openalex.org/W2108234281","https://openalex.org/W2108275997","https://openalex.org/W2108524369","https://openalex.org/W2108599624","https://openalex.org/W2108675949","https://openalex.org/W2110682604","https://openalex.org/W2111566225","https://openalex.org/W2113279317","https://openalex.org/W2113982278","https://openalex.org/W2114555403","https://openalex.org/W2114906848","https://openalex.org/W2116245614","https://openalex.org/W2117092938","https://openalex.org/W2118839461","https://openalex.org/W2118862605","https://openalex.org/W2119408585","https://openalex.org/W2119501580","https://openalex.org/W2119786102","https://openalex.org/W2120071061","https://openalex.org/W2120527686","https://openalex.org/W2120868818","https://openalex.org/W2121259844","https://openalex.org/W2122101756","https://openalex.org/W2123411559","https://openalex.org/W2123703257","https://openalex.org/W2123948067","https://openalex.org/W2124351063","https://openalex.org/W2124362171","https://openalex.org/W2124575861","https://openalex.org/W2125664865","https://openalex.org/W2125855697","https://openalex.org/W2125860227","https://openalex.org/W2128252278","https://openalex.org/W2128391328","https://openalex.org/W2128546338","https://openalex.org/W2128945836","https://openalex.org/W2129143776","https://openalex.org/W2129393569","https://openalex.org/W2130839032","https://openalex.org/W2131124686","https://openalex.org/W2132247062","https://openalex.org/W2132926880","https://openalex.org/W2133686117","https://openalex.org/W2134641433","https://openalex.org/W2135827933","https://openalex.org/W2135851628","https://openalex.org/W2136163227","https://openalex.org/W2136471711","https://openalex.org/W2136791491","https://openalex.org/W2137226645","https://openalex.org/W2138140504","https://openalex.org/W2138882607","https://openalex.org/W2140772179","https://openalex.org/W2141052558","https://openalex.org/W2141356807","https://openalex.org/W2142135601","https://openalex.org/W2142460132","https://openalex.org/W2143816691","https://openalex.org/W2144000625","https://openalex.org/W2144857752","https://openalex.org/W2144936220","https://openalex.org/W2145396867","https://openalex.org/W2145510257","https://openalex.org/W2146312600","https://openalex.org/W2147972895","https://openalex.org/W2148513816","https://openalex.org/W2148754141","https://openalex.org/W2148910155","https://openalex.org/W2150707280","https://openalex.org/W2151423292","https://openalex.org/W2151493803","https://openalex.org/W2152282949","https://openalex.org/W2152590959","https://openalex.org/W2154027215","https://openalex.org/W2154035365","https://openalex.org/W2155309921","https://openalex.org/W2155531572","https://openalex.org/W2156097782","https://openalex.org/W2156181043","https://openalex.org/W2156807664","https://openalex.org/W2156846394","https://openalex.org/W2158299807","https://openalex.org/W2158536200","https://openalex.org/W2158781457","https://openalex.org/W2159004254","https://openalex.org/W2159277368","https://openalex.org/W2159838001","https://openalex.org/W2160185093","https://openalex.org/W2160567170","https://openalex.org/W2160765822","https://openalex.org/W2161027665","https://openalex.org/W2161089076","https://openalex.org/W2161184021","https://openalex.org/W2162225517","https://openalex.org/W2162291560","https://openalex.org/W2164331758","https://openalex.org/W2166325055","https://openalex.org/W2166754225","https://openalex.org/W2166756533","https://openalex.org/W2166975941","https://openalex.org/W2167287925","https://openalex.org/W2167613231","https://openalex.org/W2167635180","https://openalex.org/W2169773990","https://openalex.org/W2170169496","https://openalex.org/W2170435863","https://openalex.org/W2171501229","https://openalex.org/W2181968411","https://openalex.org/W2182291277","https://openalex.org/W2182404474","https://openalex.org/W2184952710","https://openalex.org/W2187503591","https://openalex.org/W2279172997","https://openalex.org/W2313598701","https://openalex.org/W2410244765","https://openalex.org/W2426800780","https://openalex.org/W2514975384","https://openalex.org/W2595040220","https://openalex.org/W2782542058","https://openalex.org/W2889033677","https://openalex.org/W2921346101","https://openalex.org/W3128411208","https://openalex.org/W7019119777","https://openalex.org/W7036617910","https://openalex.org/W7099164444"],"related_works":["https://openalex.org/W2943919627","https://openalex.org/W2161089076","https://openalex.org/W2790502347","https://openalex.org/W2304122574","https://openalex.org/W2152590959","https://openalex.org/W6968004084","https://openalex.org/W2223015065","https://openalex.org/W2148396262","https://openalex.org/W2119501580","https://openalex.org/W2410244765"],"abstract_inverted_index":{"Atlantic":[0,12,88,157,198,204,294,388,487,793],"salmon":[1,13,89,158,172,205,295,326,389,488,510,671,771,794],"is":[2,15,40,57,103,150,276,466],"a":[3,16,79,167,212,260,302,506,515,556,618,673],"species":[4,124,375],"of":[5,22,46,54,81,99,107,130,147,153,162,170,179,188,211,266,278,284,316,320,329,352,370,405,417,480,509,558,602,620,626,647,662,694,726,740,744,769,777],"both":[6],"scientific":[7],"and":[8,11,34,84,127,132,159,200,209,229,232,238,243,252,273,305,335,343,347,362,376,390,495,502,524,534,599,609,650,669,715,748,759,773,783],"economic":[9,38],"importance,":[10],"farming":[14],"highly":[17,657],"profitable":[18],"industry":[19],"worldwide.":[20],"One":[21,97],"the":[23,47,52,105,128,151,160,171,176,203,250,254,264,279,282,287,325,333,353,368,412,415,448,477,539,566,580,593,600,606,624,627,648,679,687,723,735,741,757,770,774,787],"biggest":[24],"challenges":[25],"being":[26],"faced":[27],"by":[28,560],"farms,":[29,90],"which":[30,275],"affects":[31],"production":[32,489,714],"efficiency":[33,102],"results":[35,732,758],"in":[36,76,137,156,175,263,281,350,387,555,645,672,720,750,762,792],"severe":[37],"loss,":[39],"disease.":[41],"In":[42,357,755],"livestock":[43],"production,":[44],"one":[45],"approaches":[48],"taken":[49],"to":[50,58,78,92,165,182,192,201,225,301,310,332,397,443,475,482,574,588,635,686,753,779,789,798],"limit":[51],"impact":[53],"disease":[55,493,800],"outbreaks":[56],"selectively":[59],"breed":[60],"for":[61,113,121,135,197,378,468,518,543,568,737],"improved":[62,194],"resistance":[63,70,77,181,481,519,544,582,612,721,752,778],"within":[64,324,623,653],"farmed":[65],"populations.":[66],"Although":[67],"traditional":[68],"family-based":[69],"breeding":[71,111,139,572,796],"programs":[72,140,573,797],"have":[73,733],"shown":[74],"improvements":[75],"variety":[80],"bacterial,":[82],"viral":[83,484,674,708,781],"parasitic":[85],"diseases":[86,485],"on":[87,360,490,529,547,605,690],"response":[91],"selection":[93,101],"can":[94],"be":[95,142,718,790],"slow.":[96],"way":[98],"increasing":[100],"through":[104],"incorporation":[106,570],"genetic":[108,177,478,751,775],"markers":[109],"into":[110,571],"programs,":[112],"marker-assisted":[114],"or":[115],"genomic":[116,119,154,195,401],"selection.":[117],"However,":[118,259,592],"resources":[120,134,155,164,196,760,785],"cultured":[122],"aquatic":[123],"are":[125,614],"sparse,":[126],"generation":[129],"new":[131],"denser":[133],"use":[136],"selective":[138,795],"would":[141],"advantageous.":[143],"The":[144,185,435,471,536],"main":[145],"focus":[146],"this":[148,189,291,361,469,596,763],"thesis":[149,190,764],"development":[152],"application":[161],"those":[163],"gain":[166],"better":[168],"understanding":[169,768],"genome,":[173],"particularly":[174],"basis":[178,736,776],"host":[180],"infectious":[183,496],"diseases.":[184],"first":[186],"aim":[187,473],"was":[191,269,382,474,520,545,656],"develop":[193],"salmon,":[199],"characterise":[202,476],"genome":[206,297,355,772],"via":[207],"construction":[208],"analysis":[210,698],"SNP":[213],"linkage":[214,227,255,303,312,589,691],"map":[215,241],"derived":[216,462],"from":[217,373,463,505],"RAD-Sequencing":[218],"(RAD-Seq).":[219],"Approximately":[220],"6,500":[221],"SNPs":[222,235,342],"were":[223,236,246,299,308,395,409,433,441,456,527,633],"assigned":[224,300,309],"29":[226],"groups,":[228,313],"~1,800":[230],"male-segregating,":[231],"~1,400":[233],"female-segregating":[234],"ordered":[237],"positioned.":[239],"Overall":[240],"lengths":[242],"recombination":[244],"ratios":[245],"relatively":[247],"consistent":[248],"between":[249,271,286,430,447,666],"sexes":[251],"across":[253,411,659,699],"groups":[256],"(~1:1.5,":[257],"male:female).":[258],"substantial":[261],"difference":[262,280],"degree":[265],"marker":[267],"clustering":[268],"seen":[270],"males":[272],"females,":[274],"reflective":[277],"positions":[283],"chiasmata":[285],"two":[288,483,642,780],"sexes.":[289],"Using":[290,500],"map,":[292],"~4,000":[293],"reference":[296],"contigs":[298,307,386],"group,":[304,564],"112":[306],"multiple":[311],"highlighting":[314,565],"regions":[315,644,655],"homeology":[317],"(large":[318],"sections":[319],"duplicated":[321],"chromosomal":[322,345],"regions)":[323],"genome.":[327],"Alignment":[328],"SNP-flanking":[330],"sequences":[331,632],"stickleback":[334],"rainbow":[336],"trout":[337],"genomes":[338],"identified":[339,410,436,641],"putative":[340,742],"gene-associated":[341],"cross-species":[344,399,437],"orthologies,":[346],"provided":[348,734],"evidence":[349],"support":[351],"salmonid-specific":[354],"duplication.":[356],"addition,":[358],"based":[359],"other":[363,392],"publically":[364],"available":[365],"RAD-Seq":[366,385,460],"datasets,":[367],"utility":[369],"RAD-Seq-derived":[371],"data":[372,461,501],"different":[374,464],"laboratories":[377,465],"population":[379,508,557],"genetics":[380],"analyses":[381],"tested.":[383],"Short":[384],"nine":[391],"teleost":[393,450],"fish":[394,451,638],"used":[396,442,791],"identify":[398],"orthologous":[400,406,431,438],"relationships.":[402],"Several":[403],"thousands":[404],"RAD":[407,418,439],"loci":[408,419,440],"species,":[413,649],"with":[414,421,513,786],"number":[416],"decreasing":[420],"evolutionary":[422,445],"distance,":[423],"as":[424],"expected.":[425],"Previously":[426,453],"published":[427,454],"broad-level":[428],"relationships":[429,446,455],"chromosomes":[432,530],"confirmed.":[434],"estimate":[444],"ten":[449],"species.":[452,660],"recovered,":[457],"suggesting":[458],"that":[459,678,704],"useful":[467],"purpose.":[470],"second":[472],"architecture":[479],"affecting":[486],"farms:":[491],"pancreas":[492],"(PD),":[494],"pancreatic":[497],"necrosis":[498],"(IPN).":[499],"samples":[503],"collected":[504],"large":[507],"fry":[511],"challenged":[512],"PD,":[514],"high":[516],"heritability":[517],"estimated":[521],"(h2":[522],"~0.5),":[523],"four":[525,636],"QTL":[526,537,551,583,597],"identified,":[528],"3,":[531],"4,":[532],"7":[533],"23.":[535],"explaining":[538],"highest":[540],"within-family":[541],"variation":[542],"located":[546],"chromosome":[548],"3.":[549],"This":[550,640],"has":[552],"been":[553,586],"confirmed":[554],"post-smolts":[559],"an":[561],"independent":[562],"research":[563],"potential":[567,788],"its":[569],"improve":[575],"PD":[576],"resistance.":[577],"For":[578],"IPN,":[579],"major":[581],"had":[584],"previously":[585],"mapped":[587,685],"group":[590,692],"21.":[591],"mutation(s)":[594,604],"underlying":[595],"effect":[598],"consequences":[601],"these":[603,654,745],"affected":[607],"genes":[608,622,684,702,747],"relevant":[610],"biological":[611,705],"mechanisms":[613],"unknown.":[615],"To":[616],"generate":[617],"list":[619],"candidate":[621,746],"vicinity":[625],"IPN":[628,667,727],"QTL,":[629],"QTL-linked":[630],"DNA":[631],"aligned":[634],"model":[637],"genomes.":[639],"QTL-orthologous":[643,688],"each":[646],"gene":[651,663],"order":[652],"conserved":[658],"Analysis":[661],"expression":[664],"patterns":[665],"resistant":[668],"susceptible":[670],"challenge":[675],"experiment":[676],"revealed":[677],"five":[680],"most":[681],"significantly":[682],"differentially-expressed":[683,701],"region":[689],"II":[693],"stickleback.":[695],"Pathway":[696],"enrichment":[697],"all":[700],"suggests":[703],"pathways":[706,749],"influencing":[707],"infection":[709],"stress":[710],"response/entry/replication,":[711],"cellular":[712],"energy":[713],"apoptosis":[716],"may":[717],"involved":[719],"during":[722],"initial":[724],"stages":[725],"virus":[728],"(IPNV)":[729],"infection.":[730],"These":[731],"further":[738],"study":[739],"involvement":[743],"IPNV.":[754],"summary,":[756],"presented":[761],"extend":[765],"our":[766],"current":[767],"diseases,":[782],"provide":[784],"tackle":[799],"outbreaks.":[801]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-03-16T00:00:00"}