{"id":"https://openalex.org/W2591968140","doi":"https://doi.org/10.21037/jtd.2017.02.50","title":"Lower expression of platelet derived growth factor is associated with better overall survival rate of patients with idiopathic nonspecific interstitial pneumonia","display_name":"Lower expression of platelet derived growth factor is associated with better overall survival rate of patients with idiopathic nonspecific interstitial pneumonia","publication_year":2017,"publication_date":"2017-03-01","ids":{"openalex":"https://openalex.org/W2591968140","doi":"https://doi.org/10.21037/jtd.2017.02.50","mag":"2591968140","pmid":"https://pubmed.ncbi.nlm.nih.gov/28449458","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5394091"},"language":"en","primary_location":{"id":"doi:10.21037/jtd.2017.02.50","doi":"https://doi.org/10.21037/jtd.2017.02.50","is_oa":true,"landing_page_url":"https://doi.org/10.21037/jtd.2017.02.50","pdf_url":"https://jtd.amegroups.com/article/viewFile/12177/pdf","source":{"id":"https://openalex.org/S2754193772","display_name":"Journal of Thoracic Disease","issn_l":"2072-1439","issn":["2072-1439","2077-6624"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Thoracic Disease","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://jtd.amegroups.com/article/viewFile/12177/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101560073","display_name":"Xuyou Zhu","orcid":"https://orcid.org/0000-0002-0355-4960","observed_orcids":["https://orcid.org/0000-0002-0355-4960"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuyou Zhu","raw_affiliation_strings":["Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100781183","display_name":"Fang Xia","orcid":"https://orcid.org/0000-0002-0676-8606","observed_orcids":["https://orcid.org/0000-0002-0676-8606"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xia Fang","raw_affiliation_strings":["Department of Hematology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100344597","display_name":"Wei Chen","orcid":"https://orcid.org/0000-0003-4610-8490","observed_orcids":["https://orcid.org/0000-0003-4610-8490"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Chen","raw_affiliation_strings":["Department of Radiology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090937408","display_name":"Fei Han","orcid":"https://orcid.org/0000-0002-1598-9048","observed_orcids":["https://orcid.org/0000-0002-1598-9048"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fei Han","raw_affiliation_strings":["Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030478579","display_name":"Ziling Huang","orcid":"https://orcid.org/0000-0002-0899-1270","observed_orcids":["https://orcid.org/0000-0002-0899-1270"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ziling Huang","raw_affiliation_strings":["Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102199716","display_name":"Benfang Luo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210127126","display_name":"Shanghai Pulmonary Hospital","ror":"https://ror.org/033nbnf69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127126"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Benfang Luo","raw_affiliation_strings":["Department of Special Examination, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Special Examination, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210127126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101967088","display_name":"Pan Gu","orcid":"https://orcid.org/0000-0002-4323-2667","observed_orcids":["https://orcid.org/0000-0002-4323-2667"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pan Gu","raw_affiliation_strings":["Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100363498","display_name":"Long Zhang","orcid":"https://orcid.org/0000-0001-8139-0474","observed_orcids":["https://orcid.org/0000-0001-8139-0474","https://orcid.org/0009-0001-9526-3836","https://orcid.org/0000-0002-5125-0224"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Long Zhang","raw_affiliation_strings":["Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112354185","display_name":"Weizhe Qiu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weizhe Qiu","raw_affiliation_strings":["Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002857288","display_name":"Yu Zeng","orcid":"https://orcid.org/0000-0002-9415-0610","observed_orcids":["https://orcid.org/0000-0002-9415-0610"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Zeng","raw_affiliation_strings":["Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100297342","display_name":"Weiwei Rui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Weiwei Rui","raw_affiliation_strings":["Department of Pathology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China","Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China","Department of Pathology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.; Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]},{"raw_affiliation_string":"Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China","institution_ids":["https://openalex.org/I116953780"]},{"raw_affiliation_string":"Department of Pathology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.; Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102947632","display_name":"Xianghua Yi","orcid":"https://orcid.org/0000-0002-5615-9331","observed_orcids":["https://orcid.org/0000-0002-5615-9331"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xianghua Yi","raw_affiliation_strings":["Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China","institution_ids":["https://openalex.org/I116953780"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100297342","https://openalex.org/A5102947632"],"corresponding_institution_ids":["https://openalex.org/I116953780","https://openalex.org/I183067930","https://openalex.org/I2801556517"],"apc_list":null,"apc_paid":null,"fwci":0.6248,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.70689116,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":96},"biblio":{"volume":"9","issue":"3","first_page":"519","last_page":"528"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10870","display_name":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10870","display_name":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/idiopathic-nonspecific-interstitial-pneumonia","display_name":"idiopathic nonspecific interstitial pneumonia","score":0.996999979019165},{"id":"https://openalex.org/keywords/idiopathic-pulmonary-fibrosis","display_name":"idiopathic pulmonary fibrosis","score":0.9049999713897705},{"id":"https://openalex.org/keywords/platelet-derived-growth-factor","display_name":"platelet-derived growth factor","score":0.9570000171661377},{"id":"https://openalex.org/keywords/tgf-beta1","display_name":"TGF-\u03b21","score":0.8500000238418579},{"id":"https://openalex.org/keywords/fgf10","display_name":"FGF10","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cytokine-expression","display_name":"cytokine expression","score":0.9599999785423279},{"id":"https://openalex.org/keywords/pulmonary-interstitial-fibrosis","display_name":"interstitial pulmonary fibrosis","score":0.8109999895095825},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9390000104904175},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.6610000133514404},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.9010000228881836}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9058560132980347},{"id":"https://openalex.org/C2777914695","wikidata":"https://www.wikidata.org/wiki/Q12192","display_name":"Pneumonia","level":2,"score":0.5063554048538208},{"id":"https://openalex.org/C2781378642","wikidata":"https://www.wikidata.org/wiki/Q1790424","display_name":"Idiopathic interstitial pneumonia","level":4,"score":0.487473726272583},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46678316593170166},{"id":"https://openalex.org/C2994364436","wikidata":"https://www.wikidata.org/wiki/Q1153419","display_name":"Interstitial pneumonia","level":3,"score":0.4470668137073517},{"id":"https://openalex.org/C2775960820","wikidata":"https://www.wikidata.org/wiki/Q408378","display_name":"Growth factor","level":3,"score":0.44238099455833435},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.41769570112228394},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3436095118522644},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.32438400387763977},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.10910549759864807},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.05606943368911743}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.21037/jtd.2017.02.50","doi":"https://doi.org/10.21037/jtd.2017.02.50","is_oa":true,"landing_page_url":"https://doi.org/10.21037/jtd.2017.02.50","pdf_url":"https://jtd.amegroups.com/article/viewFile/12177/pdf","source":{"id":"https://openalex.org/S2754193772","display_name":"Journal of Thoracic Disease","issn_l":"2072-1439","issn":["2072-1439","2077-6624"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Thoracic Disease","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4251675","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5394091","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5394091","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5394091","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Thorac Dis","raw_type":"Text"},{"id":"pmid:28449458","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28449458","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of thoracic disease","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.21037/jtd.2017.02.50","doi":"https://doi.org/10.21037/jtd.2017.02.50","is_oa":true,"landing_page_url":"https://doi.org/10.21037/jtd.2017.02.50","pdf_url":"https://jtd.amegroups.com/article/viewFile/12177/pdf","source":{"id":"https://openalex.org/S2754193772","display_name":"Journal of Thoracic Disease","issn_l":"2072-1439","issn":["2072-1439","2077-6624"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Thoracic Disease","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G4446137518","display_name":null,"funder_award_id":"09411951600","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6803836011","display_name":null,"funder_award_id":"81570053","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2591968140.pdf","grobid_xml":"https://content.openalex.org/works/W2591968140.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W1967763945","https://openalex.org/W2004222136","https://openalex.org/W2007075196","https://openalex.org/W2016086822","https://openalex.org/W2050076172","https://openalex.org/W2050862994","https://openalex.org/W2066952595","https://openalex.org/W2069951402","https://openalex.org/W2072063652","https://openalex.org/W2083755620","https://openalex.org/W2108406461","https://openalex.org/W2113036170","https://openalex.org/W2135605951","https://openalex.org/W2148954263","https://openalex.org/W2149661971","https://openalex.org/W2150548551","https://openalex.org/W2152999504","https://openalex.org/W2167383172","https://openalex.org/W2170296643","https://openalex.org/W2238574444","https://openalex.org/W2331647948","https://openalex.org/W2333543645","https://openalex.org/W2347567005","https://openalex.org/W2400588005","https://openalex.org/W2410821524","https://openalex.org/W2416914730","https://openalex.org/W4406056548"],"related_works":["https://openalex.org/W2352923521","https://openalex.org/W3146253750","https://openalex.org/W2138934076","https://openalex.org/W1033410304","https://openalex.org/W106329705","https://openalex.org/W7112170305","https://openalex.org/W4200019348","https://openalex.org/W4411628882","https://openalex.org/W3010603139","https://openalex.org/W2399209948"],"abstract_inverted_index":{"BACKGROUND:":[0],"Idiopathic":[1],"nonspecific":[2],"interstitial":[3,11],"pneumonia":[4],"(INSIP)":[5],"presents":[6],"with":[7,99,129,165,198],"varying":[8],"degrees":[9],"of":[10,20,26,57,84,97,155,168,184,201],"inflammation":[12],"and":[13,62,74,93,101,118,133,177,186],"fibrosis":[14,65],"exhibiting":[15],"a":[16],"uniform":[17],"appearance.":[18],"Lack":[19],"knowledge":[21],"on":[22],"the":[23,55,82,147,182],"underlying":[24],"mechanisms":[25],"INSIP":[27,46,60,102,193,196],"has":[28],"contributed":[29],"to":[30,39,53,79],"few":[31],"effective":[32],"treatment":[33],"strategies.":[34],"Our":[35,171],"study":[36,172],"is":[37],"designed":[38],"explore":[40],"aberrantly":[41],"expressed":[42,86,141],"cytokines":[43,58,91,138],"involvement":[44],"in":[45,59,127,142,192],"development.":[47],"METHODS:":[48],"Oligo":[49],"GEArray":[50],"was":[51,67,139],"employed":[52],"detect":[54],"expression":[56,83,92,154,167,200],"patients,":[61],"idiopathic":[63],"pulmonary":[64],"(IPF)":[66],"setup":[68],"as":[69],"isotype":[70],"control.":[71],"Real-time":[72,131],"PCR":[73,132],"immunohistochemistry":[75,134],"analysis":[76,150],"were":[77,103,124],"used":[78],"further":[80],"confirm":[81],"abnormally":[85,140],"cytokines.":[87],"The":[88],"correlationship":[89],"between":[90],"overall":[94,160],"survival":[95,161,205],"rate":[96,162],"patients":[98,128,157,197],"IPF":[100],"analyzed.":[104],"RESULTS:":[105],"From":[106],"microarray":[107],"detection,":[108],"transforming":[109],"growth":[110,114,121],"factor-beta-1":[111],"(TGF-\u03b21),":[112],"fibroblast":[113],"factor":[115,122],"10":[116],"(FGF10),":[117],"platelet":[119],"derived":[120],"(PDGF)":[123],"predominantly":[125],"up-regulated":[126],"INSIP.":[130,143],"also":[135],"showed":[136],"these":[137],"In":[144],"addition":[145],"to,":[146],"clinical":[148],"relevance":[149],"demonstrated":[151],"relatively":[152],"lower":[153,199],"PDGF":[156,178,202],"had":[158,203],"longer":[159],"than":[163],"those":[164],"higher":[166],"PDGF.":[169],"CONCLUSIONS:":[170],"suggests":[173],"that":[174],"TGF-\u03b21,":[175],"FGF10,":[176],"are":[179],"required":[180],"for":[181],"pathogenesis":[183],"INSIP,":[185],"may":[187],"therefore":[188],"be":[189],"ideal":[190],"targets":[191],"treatment.":[194],"Moreover,":[195],"better":[204],"rate.":[206]},"counts_by_year":[{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":3}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2017-03-16T00:00:00"}