{"id":"https://openalex.org/W2591644613","doi":null,"title":"Impact d'un r\u00e9gime Western diet sur la plasticit\u00e9 du syst\u00e8me nerveux ent\u00e9rique et r\u00e9percussions fonctionnelles","display_name":"Impact d'un r\u00e9gime Western diet sur la plasticit\u00e9 du syst\u00e8me nerveux ent\u00e9rique et r\u00e9percussions fonctionnelles","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2591644613","mag":"2591644613"},"language":"fr","primary_location":{"id":"mag:2591644613","doi":null,"is_oa":false,"landing_page_url":"http://archive.bu.univ-nantes.fr/pollux/fichiers/download/41e46b21-dae4-4cc5-a33c-391eade4ecdb","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054601176","display_name":"Charlotte Baudry","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Charlotte Baudry","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5054601176"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/western-diet","display_name":"Western diet","score":0.953000009059906},{"id":"https://openalex.org/keywords/enteric-nervous-system","display_name":"enteric nervous system","score":0.9919999837875366},{"id":"https://openalex.org/keywords/myenteric-neurons","display_name":"myenteric neurons","score":0.8460000157356262},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.7680000066757202},{"id":"https://openalex.org/keywords/gastric-emptying","display_name":"gastric emptying","score":0.75},{"id":"https://openalex.org/keywords/leptin","display_name":"leptin","score":0.7699999809265137},{"id":"https://openalex.org/keywords/glial-cell-line-derived-neurotrophic-factor","display_name":"glial cell line-derived neurotrophic factor","score":0.9829999804496765},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.699999988079071},{"id":"https://openalex.org/keywords/paracellular-permeability","display_name":"paracellular permeability","score":0.7599999904632568},{"id":"https://openalex.org/keywords/claudin-1","display_name":"claudin-1","score":0.9129999876022339},{"id":"https://openalex.org/keywords/vasoactive-intestinal-peptide","display_name":"vasoactive intestinal peptide","score":0.9649999737739563},{"id":"https://openalex.org/keywords/dietary-fat","display_name":"dietary fat","score":0.48399999737739563},{"id":"https://openalex.org/keywords/dietary-sugar","display_name":"dietary sugar","score":0.6489999890327454},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.4959999918937683},{"id":"https://openalex.org/keywords/gastrointestinal-function","display_name":"gastrointestinal function","score":0.5690000057220459}],"concepts":[{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5667949318885803},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.5594752430915833},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.40485620498657227},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.38138291239738464},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.3163999915122986},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2265828251838684},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1769079566001892}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2591644613","doi":null,"is_oa":false,"landing_page_url":"http://archive.bu.univ-nantes.fr/pollux/fichiers/download/41e46b21-dae4-4cc5-a33c-391eade4ecdb","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":375,"referenced_works":["https://openalex.org/W29666767","https://openalex.org/W136248654","https://openalex.org/W173643440","https://openalex.org/W177317052","https://openalex.org/W198242003","https://openalex.org/W405439338","https://openalex.org/W1480276146","https://openalex.org/W1498038195","https://openalex.org/W1507478353","https://openalex.org/W1513588731","https://openalex.org/W1514385072","https://openalex.org/W1518421297","https://openalex.org/W1518824992","https://openalex.org/W1545460826","https://openalex.org/W1551216731","https://openalex.org/W1554042779","https://openalex.org/W1557432118","https://openalex.org/W1559486758","https://openalex.org/W1560234970","https://openalex.org/W1563139854","https://openalex.org/W1564282281","https://openalex.org/W1592927603","https://openalex.org/W1599839154","https://openalex.org/W1612135120","https://openalex.org/W1642107542","https://openalex.org/W1656060692","https://openalex.org/W1676263233","https://openalex.org/W1827038840","https://openalex.org/W1838613517","https://openalex.org/W1890463795","https://openalex.org/W1901598508","https://openalex.org/W1904109251","https://openalex.org/W1911285871","https://openalex.org/W1913424663","https://openalex.org/W1919618257","https://openalex.org/W1924396214","https://openalex.org/W1928947552","https://openalex.org/W1936199746","https://openalex.org/W1941449984","https://openalex.org/W1944771907","https://openalex.org/W1951242895","https://openalex.org/W1960059531","https://openalex.org/W1962835176","https://openalex.org/W1963746831","https://openalex.org/W1964008466","https://openalex.org/W1964038252","https://openalex.org/W1964335630","https://openalex.org/W1965106381","https://openalex.org/W1965410604","https://openalex.org/W1965622082","https://openalex.org/W1965679064","https://openalex.org/W1965930828","https://openalex.org/W1967170104","https://openalex.org/W1967825344","https://openalex.org/W1967991944","https://openalex.org/W1968154981","https://openalex.org/W1968192195","https://openalex.org/W1968788238","https://openalex.org/W1969776956","https://openalex.org/W1969838876","https://openalex.org/W1971258833","https://openalex.org/W1971668473","https://openalex.org/W1971873395","https://openalex.org/W1972276243","https://openalex.org/W1973489602","https://openalex.org/W1973655801","https://openalex.org/W1973936420","https://openalex.org/W1974584320","https://openalex.org/W1976116333","https://openalex.org/W1976259021","https://openalex.org/W1976984992","https://openalex.org/W1977348165","https://openalex.org/W1977838665","https://openalex.org/W1977872548","https://openalex.org/W1979001631","https://openalex.org/W1979185921","https://openalex.org/W1979372288","https://openalex.org/W1980059877","https://openalex.org/W1981815916","https://openalex.org/W1982761373","https://openalex.org/W1982894317","https://openalex.org/W1983141816","https://openalex.org/W1983208716","https://openalex.org/W1984545430","https://openalex.org/W1985204491","https://openalex.org/W1985267964","https://openalex.org/W1985843894","https://openalex.org/W1987513354","https://openalex.org/W1987566228","https://openalex.org/W1988842352","https://openalex.org/W1989158844","https://openalex.org/W1990436043","https://openalex.org/W1990601299","https://openalex.org/W1990711717","https://openalex.org/W1990736267","https://openalex.org/W1992108578","https://openalex.org/W1992300243","https://openalex.org/W1993442075","https://openalex.org/W1994643044","https://openalex.org/W1995375315","https://openalex.org/W1996131159","https://openalex.org/W1996634799","https://openalex.org/W1996898670","https://openalex.org/W1996912527","https://openalex.org/W1998203126","https://openalex.org/W1999027849","https://openalex.org/W1999141661","https://openalex.org/W1999190372","https://openalex.org/W2000793260","https://openalex.org/W2000953793","https://openalex.org/W2001265667","https://openalex.org/W2001887191","https://openalex.org/W2002297978","https://openalex.org/W2002689024","https://openalex.org/W2002707914","https://openalex.org/W2002767733","https://openalex.org/W2003882659","https://openalex.org/W2004982499","https://openalex.org/W2005330710","https://openalex.org/W2005355216","https://openalex.org/W2005497167","https://openalex.org/W2005894604","https://openalex.org/W2005953214","https://openalex.org/W2006218040","https://openalex.org/W2006501629","https://openalex.org/W2006542447","https://openalex.org/W2006709336","https://openalex.org/W2008752643","https://openalex.org/W2009520092","https://openalex.org/W2010682403","https://openalex.org/W2011081855","https://openalex.org/W2011325404","https://openalex.org/W2011367927","https://openalex.org/W2011847859","https://openalex.org/W2011848992","https://openalex.org/W2012800693","https://openalex.org/W2013442941","https://openalex.org/W2017136878","https://openalex.org/W2017351996","https://openalex.org/W2018936034","https://openalex.org/W2019752999","https://openalex.org/W2019982943","https://openalex.org/W2020320796","https://openalex.org/W2020892577","https://openalex.org/W2022633717","https://openalex.org/W2022832699","https://openalex.org/W2023691179","https://openalex.org/W2023818252","https://openalex.org/W2025204456","https://openalex.org/W2025829758","https://openalex.org/W2026470798","https://openalex.org/W2027322371","https://openalex.org/W2027918140","https://openalex.org/W2028300244","https://openalex.org/W2028358869","https://openalex.org/W2032006080","https://openalex.org/W2032118416","https://openalex.org/W2032123628","https://openalex.org/W2032422271","https://openalex.org/W2032984191","https://openalex.org/W2033141014","https://openalex.org/W2033798970","https://openalex.org/W2034794405","https://openalex.org/W2035600812","https://openalex.org/W2036294223","https://openalex.org/W2036509924","https://openalex.org/W2036781343","https://openalex.org/W2038418093","https://openalex.org/W2039665401","https://openalex.org/W2039901999","https://openalex.org/W2040119336","https://openalex.org/W2041467363","https://openalex.org/W2041910944","https://openalex.org/W2042358571","https://openalex.org/W2042371226","https://openalex.org/W2042933256","https://openalex.org/W2043279725","https://openalex.org/W2043428150","https://openalex.org/W2044152741","https://openalex.org/W2044183089","https://openalex.org/W2044895919","https://openalex.org/W2045160411","https://openalex.org/W2045520426","https://openalex.org/W2046961168","https://openalex.org/W2048920781","https://openalex.org/W2049449334","https://openalex.org/W2049588755","https://openalex.org/W2052540984","https://openalex.org/W2052695206","https://openalex.org/W2055210467","https://openalex.org/W2055776762","https://openalex.org/W2056795725","https://openalex.org/W2056809047","https://openalex.org/W2057186841","https://openalex.org/W2057772959","https://openalex.org/W2057850960","https://openalex.org/W2058585578","https://openalex.org/W2058971418","https://openalex.org/W2059990910","https://openalex.org/W2060745099","https://openalex.org/W2061350896","https://openalex.org/W2062299214","https://openalex.org/W2062364754","https://openalex.org/W2062401660","https://openalex.org/W2063191706","https://openalex.org/W2064492226","https://openalex.org/W2064732729","https://openalex.org/W2065367452","https://openalex.org/W2065818402","https://openalex.org/W2066486037","https://openalex.org/W2066673842","https://openalex.org/W2068379647","https://openalex.org/W2068634777","https://openalex.org/W2068755072","https://openalex.org/W2069142753","https://openalex.org/W2069540511","https://openalex.org/W2069991462","https://openalex.org/W2073723117","https://openalex.org/W2077335475","https://openalex.org/W2077613416","https://openalex.org/W2077656589","https://openalex.org/W2078769055","https://openalex.org/W2080225021","https://openalex.org/W2081316343","https://openalex.org/W2082015820","https://openalex.org/W2082135288","https://openalex.org/W2082156702","https://openalex.org/W2082584428","https://openalex.org/W2082674782","https://openalex.org/W2082856711","https://openalex.org/W2083095583","https://openalex.org/W2083147722","https://openalex.org/W2083912490","https://openalex.org/W2084824515","https://openalex.org/W2085062842","https://openalex.org/W2085218910","https://openalex.org/W2086213189","https://openalex.org/W2086330266","https://openalex.org/W2086627748","https://openalex.org/W2087022299","https://openalex.org/W2087133453","https://openalex.org/W2087451964","https://openalex.org/W2087705354","https://openalex.org/W2088409711","https://openalex.org/W2089031162","https://openalex.org/W2089876789","https://openalex.org/W2090129399","https://openalex.org/W2090668782","https://openalex.org/W2090713876","https://openalex.org/W2090776773","https://openalex.org/W2091661565","https://openalex.org/W2091858438","https://openalex.org/W2092612823","https://openalex.org/W2093666272","https://openalex.org/W2094205321","https://openalex.org/W2094759401","https://openalex.org/W2095601375","https://openalex.org/W2096194550","https://openalex.org/W2096459471","https://openalex.org/W2097098003","https://openalex.org/W2098267014","https://openalex.org/W2098375330","https://openalex.org/W2098586830","https://openalex.org/W2098851817","https://openalex.org/W2099767750","https://openalex.org/W2099941593","https://openalex.org/W2100012692","https://openalex.org/W2100412897","https://openalex.org/W2102471840","https://openalex.org/W2103464278","https://openalex.org/W2103567658","https://openalex.org/W2105894053","https://openalex.org/W2105946812","https://openalex.org/W2105987351","https://openalex.org/W2107277218","https://openalex.org/W2107330366","https://openalex.org/W2107601924","https://openalex.org/W2110999037","https://openalex.org/W2112037418","https://openalex.org/W2112202133","https://openalex.org/W2112454216","https://openalex.org/W2112831360","https://openalex.org/W2113272099","https://openalex.org/W2115250115","https://openalex.org/W2115387631","https://openalex.org/W2115501504","https://openalex.org/W2116963389","https://openalex.org/W2118505191","https://openalex.org/W2126155923","https://openalex.org/W2126918525","https://openalex.org/W2127109571","https://openalex.org/W2128091095","https://openalex.org/W2128240614","https://openalex.org/W2129207762","https://openalex.org/W2129917444","https://openalex.org/W2130507030","https://openalex.org/W2131361751","https://openalex.org/W2132168348","https://openalex.org/W2132654540","https://openalex.org/W2135406319","https://openalex.org/W2135983377","https://openalex.org/W2139520660","https://openalex.org/W2139836251","https://openalex.org/W2140598936","https://openalex.org/W2140929617","https://openalex.org/W2143395595","https://openalex.org/W2143752451","https://openalex.org/W2144388973","https://openalex.org/W2144632432","https://openalex.org/W2144982081","https://openalex.org/W2146279529","https://openalex.org/W2146290584","https://openalex.org/W2147189912","https://openalex.org/W2149362355","https://openalex.org/W2150094887","https://openalex.org/W2151566924","https://openalex.org/W2152828466","https://openalex.org/W2154486005","https://openalex.org/W2155236015","https://openalex.org/W2156272127","https://openalex.org/W2157077335","https://openalex.org/W2157259632","https://openalex.org/W2158018898","https://openalex.org/W2158594746","https://openalex.org/W2159003687","https://openalex.org/W2159590405","https://openalex.org/W2159745814","https://openalex.org/W2161364374","https://openalex.org/W2161533269","https://openalex.org/W2161751637","https://openalex.org/W2162267515","https://openalex.org/W2163092495","https://openalex.org/W2163655541","https://openalex.org/W2163702170","https://openalex.org/W2168184759","https://openalex.org/W2168741394","https://openalex.org/W2168769987","https://openalex.org/W2168846515","https://openalex.org/W2169565924","https://openalex.org/W2169705149","https://openalex.org/W2170464608","https://openalex.org/W2170880987","https://openalex.org/W2171561168","https://openalex.org/W2173892503","https://openalex.org/W2180879622","https://openalex.org/W2181227865","https://openalex.org/W2181871939","https://openalex.org/W2184874099","https://openalex.org/W2187110352","https://openalex.org/W2188877806","https://openalex.org/W2281501116","https://openalex.org/W2312932008","https://openalex.org/W2319367287","https://openalex.org/W2324912146","https://openalex.org/W2327122843","https://openalex.org/W2334337188","https://openalex.org/W2399569782","https://openalex.org/W2402183013","https://openalex.org/W2407465444","https://openalex.org/W2413392065","https://openalex.org/W2416028700","https://openalex.org/W2416432034","https://openalex.org/W2417248700","https://openalex.org/W2419078255","https://openalex.org/W2430142031","https://openalex.org/W2471756629","https://openalex.org/W2474527850","https://openalex.org/W2474660236","https://openalex.org/W2580292786","https://openalex.org/W2808176952","https://openalex.org/W2894613750","https://openalex.org/W2941087694","https://openalex.org/W2978639827","https://openalex.org/W3192790212","https://openalex.org/W4302357158"],"related_works":["https://openalex.org/W2098437387","https://openalex.org/W2579384716","https://openalex.org/W2070034873","https://openalex.org/W7149298115","https://openalex.org/W4417322852","https://openalex.org/W2035101754","https://openalex.org/W1984054593","https://openalex.org/W2734632372","https://openalex.org/W1977542029","https://openalex.org/W4392537915"],"abstract_inverted_index":{"Le":[0],"systeme":[1,7],"nerveux":[2,8],"enterique":[3],"(SNE)":[4],"est":[5],"un":[6,232,244],"integratif,":[9],"innervant":[10],"l'ensemble":[11],"du":[12,28,61,114,138,140,180,217],"tube":[13],"digestif,":[14],"qui":[15],"controle":[16],"les":[17,33,59,87,94,173,237],"fonctions":[18,34,240],"gastro-intestinales":[19],"(GI).":[20],"Certains":[21],"facteurs":[22],"nutritionnels":[23,72],"peuvent":[24],"moduler":[25],"le":[26,45,83,170,193,223,229],"phenotype":[27,139],"SNE":[29,46,84,141,230],"et":[30,78,91,154,169,216],"ainsi":[31,85],"modifier":[32],"GI.":[35],"Cependant,":[36],"l'impact":[37],"a":[38,128,144,155,204],"long":[39],"terme":[40],"d'un":[41],"desequilibre":[42],"nutritionnel":[43],"sur":[44,82],"reste":[47],"largement":[48],"inconnu.":[49],"Les":[50],"objectifs":[51],"de":[52,97,104,147,158,187,199,207,209,212],"ce":[53],"travail":[54],"etaient":[55,142],"donc":[56,228],"1)":[57],"d'etudier":[58],"effets":[60,178],"regime":[62,115,181,194,245],"\u00ab":[63],"Western":[64],"diet":[65],"\u00bb":[66],"(WD),":[67],"caracterise":[68],"par":[69,243],"des":[70,123,133,239],"apports":[71],"excessifs":[73],"en":[74,79,109],"acides":[75],"gras":[76],"satures":[77],"glucides":[80],"simples,":[81],"que":[86,111,192],"repercussions":[88],"fonctionnelles":[89],"associees":[90,143],"2)":[92],"d'identifier":[93],"mediateurs":[95,174],"responsables":[96],"ces":[98,177],"modifications.":[99],"Dans":[100,183],"la":[101,112,121,148,159,167,184,200,210],"premiere":[102],"partie":[103,186],"l'etude,":[105,188],"nous":[106,164,189],"avons":[107,165,190],"mis":[108],"evidence":[110],"consommation":[113],"WD":[116,195],"pendant":[117],"12":[118],"semaines":[119],"prevenait":[120],"perte":[122],"neurones":[124],"myenteriques":[125],"nitrergiques,":[126],"associee":[127,203],"l'\u00e2ge,":[129],"observee":[130],"dans":[131,152,176,222,236],"l'antre":[132,153],"souris":[134],"controles.":[135],"Ces":[136],"modifications":[137,238],"une":[145,156,197,205],"augmentation":[146,206],"transmission":[149],"neuromusculaire":[150],"nitrergique":[151],"acceleration":[157],"vidange":[160],"gastrique.":[161],"De":[162],"plus,":[163],"identifie":[166,227],"leptine":[168],"GDNF":[171],"comme":[172,231],"impliques":[175],"neuroprotecteurs":[179],"WD.":[182,246],"seconde":[185],"observe":[191],"entrainait":[196],"diminution":[198],"permeabilite":[201],"paracellulaire,":[202],"l'expression":[208],"proteine":[211],"jonction":[213],"serree":[214],"Claudine-1":[215],"peptide":[218],"intestinal":[219],"vasoactif":[220],"(VIP)":[221],"jejunum.":[224],"Cette":[225],"etude":[226],"nouvel":[233],"acteur":[234],"implique":[235],"GI":[241],"induites":[242]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-03-16T00:00:00"}
