{"id":"https://openalex.org/W2591383121","doi":"https://doi.org/10.3354/dao03113","title":"Evidence of horizontal transmission of the cancer-associated Steamer retrotransposon among ecological cohort bivalve species","display_name":"Evidence of horizontal transmission of the cancer-associated Steamer retrotransposon among ecological cohort bivalve species","publication_year":2017,"publication_date":"2017-02-21","ids":{"openalex":"https://openalex.org/W2591383121","doi":"https://doi.org/10.3354/dao03113","mag":"2591383121","pmid":"https://pubmed.ncbi.nlm.nih.gov/28425429"},"language":"en","primary_location":{"id":"doi:10.3354/dao03113","doi":"https://doi.org/10.3354/dao03113","is_oa":true,"landing_page_url":"https://doi.org/10.3354/dao03113","pdf_url":"https://www.int-res.com/articles/dao2017/124/d124p165.pdf","source":{"id":"https://openalex.org/S49731288","display_name":"Diseases of Aquatic Organisms","issn_l":"0177-5103","issn":["0177-5103","1616-1580"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313773","host_organization_name":"Inter-Research","host_organization_lineage":["https://openalex.org/P4310313773"],"host_organization_lineage_names":["Inter-Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diseases of Aquatic Organisms","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.int-res.com/articles/dao2017/124/d124p165.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5096929620","display_name":"AN Paynter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1338124936","display_name":"American Museum of Natural History","ror":"https://ror.org/03thb3e06","country_code":"US","type":"archive","lineage":["https://openalex.org/I1338124936"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"AN Paynter","raw_affiliation_strings":["Sackler Institute of Comparative Genomics, American Museum of Natural History, New York, New York 10024, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sackler Institute of Comparative Genomics, American Museum of Natural History, New York, New York 10024, USA","institution_ids":["https://openalex.org/I1338124936"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066955907","display_name":"Michael J. Metzger","orcid":"https://orcid.org/0000-0001-7855-1388","observed_orcids":["https://orcid.org/0000-0001-7855-1388"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"MJ Metzger","raw_affiliation_strings":["Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021999796","display_name":"Jocelyn Anne Sessa","orcid":"https://orcid.org/0000-0003-1509-5519","observed_orcids":["https://orcid.org/0000-0003-1509-5519"]},"institutions":[{"id":"https://openalex.org/I1338124936","display_name":"American Museum of Natural History","ror":"https://ror.org/03thb3e06","country_code":"US","type":"archive","lineage":["https://openalex.org/I1338124936"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JA Sessa","raw_affiliation_strings":["Division of Paleontology, American Museum of Natural History, New York, New York 10024, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Paleontology, American Museum of Natural History, New York, New York 10024, USA","institution_ids":["https://openalex.org/I1338124936"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075627115","display_name":"Mark Edward Siddall","orcid":"https://orcid.org/0000-0002-3977-7517","observed_orcids":["https://orcid.org/0000-0002-3977-7517"]},"institutions":[{"id":"https://openalex.org/I1338124936","display_name":"American Museum of Natural History","ror":"https://ror.org/03thb3e06","country_code":"US","type":"archive","lineage":["https://openalex.org/I1338124936"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"ME Siddall","raw_affiliation_strings":["Sackler Institute of Comparative Genomics, American Museum of Natural History, New York, New York 10024, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sackler Institute of Comparative Genomics, American Museum of Natural History, New York, New York 10024, USA","institution_ids":["https://openalex.org/I1338124936"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5075627115"],"corresponding_institution_ids":["https://openalex.org/I1338124936"],"apc_list":null,"apc_paid":null,"fwci":1.3246,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.79246214,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"124","issue":"2","first_page":"165","last_page":"168"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11088","display_name":"Marine Bivalve and Aquaculture Studies","score":0.45509999990463257,"subfield":{"id":"https://openalex.org/subfields/2306","display_name":"Global and Planetary Change"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11088","display_name":"Marine Bivalve and Aquaculture Studies","score":0.45509999990463257,"subfield":{"id":"https://openalex.org/subfields/2306","display_name":"Global and Planetary Change"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.15889999270439148,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13385","display_name":"Infectious Diseases and Mycology","score":0.05180000141263008,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/horizontal-transmission","display_name":"horizontal transmission","score":0.7160000205039978},{"id":"https://openalex.org/keywords/bivalvia","display_name":"Bivalvia","score":0.7059999704360962},{"id":"https://openalex.org/keywords/mya-arenaria","display_name":"Mya arenaria","score":0.8640000224113464},{"id":"https://openalex.org/keywords/ensis-directus","display_name":"Ensis directus","score":0.9350000023841858},{"id":"https://openalex.org/keywords/macoma-balthica","display_name":"Macoma balthica","score":0.984000027179718},{"id":"https://openalex.org/keywords/mya-truncata","display_name":"Mya truncata","score":0.8230000138282776},{"id":"https://openalex.org/keywords/ltr-retrotransposons","display_name":"LTR retrotransposons","score":0.7639999985694885},{"id":"https://openalex.org/keywords/genetic-polymorphism","display_name":"genetic polymorphism","score":0.4959999918937683},{"id":"https://openalex.org/keywords/cross-species-transmission","display_name":"interspecies transmission","score":0.546999990940094}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9008145332336426},{"id":"https://openalex.org/C7029365","wikidata":"https://www.wikidata.org/wiki/Q413988","display_name":"Retrotransposon","level":5,"score":0.6804816722869873},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.5304804444313049},{"id":"https://openalex.org/C2779586492","wikidata":"https://www.wikidata.org/wiki/Q25368","display_name":"Bivalvia","level":3,"score":0.5034729838371277},{"id":"https://openalex.org/C2780263730","wikidata":"https://www.wikidata.org/wiki/Q4254955","display_name":"Horizontal transmission","level":3,"score":0.456490695476532},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.44330573081970215},{"id":"https://openalex.org/C2776249982","wikidata":"https://www.wikidata.org/wiki/Q25326","display_name":"Mollusca","level":2,"score":0.4120478928089142},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.13024574518203735},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12748512625694275},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08636316657066345},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.0},{"id":"https://openalex.org/C4918238","wikidata":"https://www.wikidata.org/wiki/Q121438","display_name":"Transposable element","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017753","descriptor_name":"Ecosystem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018626","descriptor_name":"Retroelements","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020079","descriptor_name":"Terminal Repeat Sequences","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022761","descriptor_name":"Gene Transfer, Horizontal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D049872","descriptor_name":"Bivalvia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.3354/dao03113","doi":"https://doi.org/10.3354/dao03113","is_oa":true,"landing_page_url":"https://doi.org/10.3354/dao03113","pdf_url":"https://www.int-res.com/articles/dao2017/124/d124p165.pdf","source":{"id":"https://openalex.org/S49731288","display_name":"Diseases of Aquatic Organisms","issn_l":"0177-5103","issn":["0177-5103","1616-1580"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313773","host_organization_name":"Inter-Research","host_organization_lineage":["https://openalex.org/P4310313773"],"host_organization_lineage_names":["Inter-Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diseases of Aquatic Organisms","raw_type":"journal-article"},{"id":"pmid:28425429","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28425429","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diseases of aquatic organisms","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3354/dao03113","doi":"https://doi.org/10.3354/dao03113","is_oa":true,"landing_page_url":"https://doi.org/10.3354/dao03113","pdf_url":"https://www.int-res.com/articles/dao2017/124/d124p165.pdf","source":{"id":"https://openalex.org/S49731288","display_name":"Diseases of Aquatic Organisms","issn_l":"0177-5103","issn":["0177-5103","1616-1580"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313773","host_organization_name":"Inter-Research","host_organization_lineage":["https://openalex.org/P4310313773"],"host_organization_lineage_names":["Inter-Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diseases of Aquatic Organisms","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4000000059604645,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320337398","display_name":"Division of Biological Infrastructure","ror":"https://ror.org/04qn9mx93"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2591383121.pdf","grobid_xml":"https://content.openalex.org/works/W2591383121.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W153145707","https://openalex.org/W782155171","https://openalex.org/W1981770389","https://openalex.org/W2006396039","https://openalex.org/W2028459965","https://openalex.org/W2046729564","https://openalex.org/W2054011384","https://openalex.org/W2055043387","https://openalex.org/W2068902665","https://openalex.org/W2102636611","https://openalex.org/W2120031387","https://openalex.org/W2128786960","https://openalex.org/W2132201824","https://openalex.org/W2132926880","https://openalex.org/W2156057520","https://openalex.org/W2172820226","https://openalex.org/W2286798358","https://openalex.org/W2290440481","https://openalex.org/W2417772597","https://openalex.org/W2469746193","https://openalex.org/W2480496572","https://openalex.org/W2507580061","https://openalex.org/W2611511275"],"related_works":["https://openalex.org/W2799939428","https://openalex.org/W2028459965","https://openalex.org/W4395677897","https://openalex.org/W4387266858","https://openalex.org/W4405133602","https://openalex.org/W4210414577","https://openalex.org/W2469746193","https://openalex.org/W7165646201","https://openalex.org/W4414606031","https://openalex.org/W4223442268"],"abstract_inverted_index":{"Bivalve":[0],"specimens":[1,106,128],"from":[2,61],"legacy":[3],"frozen":[4],"tissue":[5],"collections,":[6],"and":[7,49,56,81,101,118,172],"others":[8],"freshly":[9],"obtained,":[10],"were":[11,65,93,102],"surveyed":[12],"for":[13,40,148],"the":[14,17,29,41,62,112,131,145,167,173],"presence":[15],"of":[16,28,70,88,107,133,151,163,166,175],"Steamer":[18,71,91,152,168,176],"long":[19],"terminal":[20],"repeat":[21],"(LTR)-retrotransposon":[22],"associated":[23],"with":[24],"disseminated":[25],"hemic":[26],"neoplasia":[27],"soft-shelled":[30],"clam":[31],"Mya":[32,79],"areneria.":[33],"Of":[34],"22":[35],"species":[36,180],"investigated":[37],"using":[38],"primers":[39],"pol":[42],"region,":[43],"only":[44],"Atlantic":[45,48,141],"M.":[46,98],"arenaria,":[47],"North":[50,63],"Sea":[51,64],"razor":[52,142],"clams":[53,58,143],"Ensis":[54],"directus,":[55],"Baltic":[57],"Macoma":[59],"balthica":[60],"found":[66],"to":[67,130],"possess":[68],"copies":[69],"in":[72,96,111,126,177],"their":[73],"genomes.":[74],"Notably,":[75],"close":[76],"relatives":[77],"like":[78],"truncata":[80],"Siliqua":[82],"patula":[83],"did":[84],"not":[85],"exhibit":[86],"evidence":[87],"Steamer.":[89],"Amplified":[90],"sequences":[92],"uniformly":[94],"identical":[95],"all":[97],"areneria":[99],"specimens,":[100],"highly":[103],"variable":[104],"across":[105],"E.":[108],"directus.":[109],"Variation":[110],"latter":[113],"included":[114],"nucleotide":[115],"polymorphisms":[116],"among":[117,153],"within":[119],"individuals":[120],"as":[121,123,144],"well":[122],"length":[124],"variation":[125],"2":[127],"corresponding":[129],"deletion":[132],"a":[134],"predicted":[135],"stable":[136],"hairpin":[137],"structure.":[138],"Results":[139],"implicate":[140],"proximal":[146],"source":[147],"horizontal":[149],"transmission":[150,165],"ecologically":[154],"similar":[155],"yet":[156],"markedly":[157],"distantly":[158],"related":[159],"bivalves.":[160],"The":[161],"consequences":[162],"cross-species":[164],"retrotransposon":[169],"are":[170],"unknown,":[171],"finding":[174],"3":[178],"bivalve":[179],"suggests":[181],"that":[182],"further":[183],"spread":[184],"is":[185],"possible.":[186]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2017-03-03T00:00:00"}