{"id":"https://openalex.org/W2591140141","doi":"https://doi.org/10.1200/jco.2011.29.15_suppl.e15155","title":"Treatment of brain metastases in patients with testicular germ cell tumors.","display_name":"Treatment of brain metastases in patients with testicular germ cell tumors.","publication_year":2011,"publication_date":"2011-05-20","ids":{"openalex":"https://openalex.org/W2591140141","doi":"https://doi.org/10.1200/jco.2011.29.15_suppl.e15155","mag":"2591140141"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2011.29.15_suppl.e15155","doi":"https://doi.org/10.1200/jco.2011.29.15_suppl.e15155","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2011.29.15_suppl.e15155","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040890872","display_name":"Jorge Mart\u00ednez-Cedillo","orcid":"https://orcid.org/0000-0001-6952-7191","observed_orcids":["https://orcid.org/0000-0001-6952-7191"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"J. Martinez-Cedillo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5040890872"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"29","issue":"15_suppl","first_page":"e15155","last_page":"e15155"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11600","display_name":"Brain Metastases and Treatment","score":0.9419000148773193,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11600","display_name":"Brain Metastases and Treatment","score":0.9419000148773193,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11069","display_name":"Testicular diseases and treatments","score":0.030500000342726707,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brain-metastases","display_name":"brain metastases","score":0.9679999947547913},{"id":"https://openalex.org/keywords/testicular-germ-cell-tumors","display_name":"testicular germ cell tumors","score":0.9929999709129333},{"id":"https://openalex.org/keywords/whole-brain-radiotherapy","display_name":"whole brain radiotherapy","score":0.8240000009536743},{"id":"https://openalex.org/keywords/surgical-resection-of-brain-metastases","display_name":"surgical resection of brain metastases","score":0.8119999766349792},{"id":"https://openalex.org/keywords/cisplatin-based-chemotherapy","display_name":"cisplatin-based chemotherapy","score":0.9869999885559082},{"id":"https://openalex.org/keywords/yolk-sac-tumor","display_name":"yolk sac tumor","score":0.8410000205039978},{"id":"https://openalex.org/keywords/mature-teratoma","display_name":"mature teratoma","score":0.7760000228881836},{"id":"https://openalex.org/keywords/choriocarcinoma","display_name":"choriocarcinoma","score":0.8759999871253967},{"id":"https://openalex.org/keywords/embryonal-carcinoma","display_name":"embryonal carcinoma","score":0.9940000176429749},{"id":"https://openalex.org/keywords/long-term-survival","display_name":"long-term survival","score":0.8080000281333923},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.6439999938011169},{"id":"https://openalex.org/keywords/time-to-recurrence","display_name":"time to recurrence","score":0.42899999022483826}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9645586609840393},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.6654825210571289},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.609403133392334},{"id":"https://openalex.org/C57742111","wikidata":"https://www.wikidata.org/wiki/Q7168","display_name":"Histology","level":2,"score":0.573907196521759},{"id":"https://openalex.org/C2778164965","wikidata":"https://www.wikidata.org/wiki/Q1620196","display_name":"Brain metastasis","level":4,"score":0.5112361907958984},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4328327775001526},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.36549052596092224},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.35429102182388306},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.3353434205055237},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.275592565536499}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1200/jco.2011.29.15_suppl.e15155","doi":"https://doi.org/10.1200/jco.2011.29.15_suppl.e15155","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2011.29.15_suppl.e15155","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2597749752","https://openalex.org/W1560694016","https://openalex.org/W2030428848","https://openalex.org/W1931939377","https://openalex.org/W79176273","https://openalex.org/W2059402303","https://openalex.org/W4377042724","https://openalex.org/W2025100610","https://openalex.org/W2052134732","https://openalex.org/W7145569674"],"abstract_inverted_index":{"e15155":[0],"Background:":[1],"Patients":[2,267,308],"with":[3,7,17,45,134,139,143,149,181,202,231,238,246,262,270,297,306,309],"TGCT":[4,49],"who":[5,212,224,235,268,281,325],"present":[6,21,282],"brain":[8,22,46,65,104,136,155,182,203,214,263,271],"metastases":[9,18,47,66,105,156,183,204,215,264,272,310,327],"have":[10,330],"poor":[11,331],"prognosis.":[12],"Approximately":[13],"3%":[14],"of":[15,32,42,64,72,96,154,221,233],"patients":[16,44,91,97,102,128,132,161,166,175,180,201,223,234,261,295,324],"disease":[19],"will":[20],"metastases.":[23],"There":[24],"are":[25,228,250],"few":[26,289],"reports":[27],"reporting":[28],"the":[29,39,73,185,217,322,337],"long-term":[30,40],"results":[31,41],"these":[33],"patients.":[34],"Methods:":[35],"We":[36],"retrospectively":[37],"report":[38],"18":[43],"from":[48,54,265],"presented":[50,133,269],"at":[51,62,106,205,273,311],"our":[52],"institute":[53],"2000":[55],"-":[56],"2010.":[57],"Results:":[58],"The":[59,70,117,152,194,241],"median":[60,187,195],"age":[61],"diagnoses":[63,107,206,275,312],"was":[67,157,191,197],"24.7":[68],"years.":[69],"histology":[71],"primary":[74,274],"tumor":[75,79],"was:":[76],"yolk":[77],"sac":[78],"12":[80],"patients,mature":[81],"teratoma":[82],"9,":[83],"coricocarcinoma":[84],"8":[85,109],"and":[86,108,124,146,172,207,248,333],"embrional":[87],"carcinoma":[88],"8.":[89],"All":[90,174],"had":[92,98,103,276,299],"mixed":[93],"histology,":[94],"none":[95],"pure":[99],"histology.":[100],"10":[101],"developed":[110,213,326],"them":[111,283],"during":[112,184,216],"follow-up":[113],"after":[114,284,328],"cisplatin-based":[115,177],"chemotherapy.":[116,178,285],"main":[118],"neurological":[119],"symptoms":[120],"were":[121,129,236,244,288],"headache,":[122],"seizures":[123],"disorientation.":[125],"Only":[126],"2":[127,140],"asymptomatic.":[130],"Ten":[131],"one":[135,147,169],"lesion,":[137],"4":[138,150,165,220],"lesions,":[141,145],"3":[142,144,232],"patient":[148,170,242],"lesions.":[151],"treatment":[153,316],"as":[158],"follow:":[159],"13":[160,222],"whole-brain":[162],"irradiation":[163],"only,":[164,168],"surgery":[167,171,239,249,298],"RT.":[173,307],"received":[176,225],"In":[179],"follow-up,":[186],"time":[188],"to":[189],"recurrence":[190],"9.1":[192],"months.":[193],"survival":[196,256],"60":[198],"months":[199,209],"for":[200,210,318],"41":[208],"those":[211,280,304],"follow":[218],"up.":[219],"RT":[226,247],"only":[227],"alive":[229],"compared":[230],"treated":[237,245,296,305],"alone.":[240],"that":[243,294],"also":[251],"alive.":[252],"Conclusions:":[253],"Long":[254],"term":[255],"can":[257,292],"be":[258],"achieved":[259],"in":[260],"TGCT.":[266],"better":[277,301],"prognosis":[278,302,332],"than":[279,303],"Although":[286],"there":[287],"patients,":[290],"we":[291],"see":[293],"a":[300,342],"should":[313,335],"receive":[314,336],"intense":[315],"modalities":[317],"curative":[319],"intent.":[320],"On":[321],"contrary,":[323],"chemotherapy":[329],"maybe":[334],"least":[338],"toxic":[339],"treatment,":[340],"like":[341],"palliative":[343],"radiation":[344],"therapy.":[345]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-03-03T00:00:00"}