{"id":"https://openalex.org/W25904378","doi":null,"title":"Lowering glycemic index of food by acarbose and Plantago psyllium mucilage.","display_name":"Lowering glycemic index of food by acarbose and Plantago psyllium mucilage.","publication_year":1998,"publication_date":"1998-01-01","ids":{"openalex":"https://openalex.org/W25904378","mag":"25904378","pmid":"https://pubmed.ncbi.nlm.nih.gov/9650328"},"language":"en","primary_location":{"id":"pmid:9650328","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9650328","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of medical research","raw_type":"Clinical Trial"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007174558","display_name":"Alberto C. Frati Munari","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136171","display_name":"Hospital de Especialidades","ror":"https://ror.org/04f86t017","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210136171"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"A C Frati Munari","raw_affiliation_strings":["Departamento de Medicina Interna, Hospital de Especialidades, M\u00e9xico, D.F"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Medicina Interna, Hospital de Especialidades, M\u00e9xico, D.F","institution_ids":["https://openalex.org/I4210136171"]}]},{"author_position":"middle","author":{"id":null,"display_name":"W Ben\u00edtez Pinto","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W Ben\u00edtez Pinto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055376899","display_name":"Cuauht\u00e9moc Ra\u00fal Ariza Andraca","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Ra\u00fal Ariza Andraca","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5010675046","display_name":"M Casarrubias","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Casarrubias","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1257,"has_fulltext":false,"cited_by_count":45,"citation_normalized_percentile":{"value":0.76146061,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"29","issue":"2","first_page":"137","last_page":"41"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10140","display_name":"Food composition and properties","score":0.9663000106811523,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10140","display_name":"Food composition and properties","score":0.9663000106811523,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.029899999499320984,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12192","display_name":"Polysaccharides Composition and Applications","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glycemic-index","display_name":"glycemic index","score":0.925000011920929},{"id":"https://openalex.org/keywords/acarbose","display_name":"acarbose","score":0.9959999918937683},{"id":"https://openalex.org/keywords/white-bread","display_name":"white bread","score":0.8410000205039978},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9369999766349792},{"id":"https://openalex.org/keywords/serum-glucose","display_name":"serum glucose","score":0.7630000114440918},{"id":"https://openalex.org/keywords/insulin-response","display_name":"insulin response","score":0.824999988079071},{"id":"https://openalex.org/keywords/antidiabetic-drugs","display_name":"antidiabetic drugs","score":0.6650000214576721},{"id":"https://openalex.org/keywords/dietary-fiber","display_name":"dietary fiber","score":0.6129999756813049}],"concepts":[{"id":"https://openalex.org/C2779372120","wikidata":"https://www.wikidata.org/wiki/Q430675","display_name":"Psyllium","level":3,"score":0.9616837501525879},{"id":"https://openalex.org/C2776617576","wikidata":"https://www.wikidata.org/wiki/Q338005","display_name":"Acarbose","level":3,"score":0.9546031355857849},{"id":"https://openalex.org/C2776652674","wikidata":"https://www.wikidata.org/wiki/Q273924","display_name":"Glycemic index","level":4,"score":0.8011494278907776},{"id":"https://openalex.org/C2780658084","wikidata":"https://www.wikidata.org/wiki/Q311228","display_name":"Plantago ovata","level":2,"score":0.7623589038848877},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6085293292999268},{"id":"https://openalex.org/C99696124","wikidata":"https://www.wikidata.org/wiki/Q424275","display_name":"Mucilage","level":2,"score":0.5807809829711914},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.561188280582428},{"id":"https://openalex.org/C2780473172","wikidata":"https://www.wikidata.org/wiki/Q5572518","display_name":"Glycemic","level":3,"score":0.5418776273727417},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5006463527679443},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.4075585901737213},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3701756000518799},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.36304616928100586},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.24952277541160583},{"id":"https://openalex.org/C2992741425","wikidata":"https://www.wikidata.org/wiki/Q215210","display_name":"Dietary fiber","level":2,"score":0.0779573917388916},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07078957557678223},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.06291258335113525}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001939","descriptor_name":"Bread","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D004043","descriptor_name":"Dietary Fiber","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004791","descriptor_name":"Enzyme Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010943","descriptor_name":"Plantago","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010946","descriptor_name":"Plants, Medicinal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014312","descriptor_name":"Trisaccharides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D020909","descriptor_name":"Acarbose","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:9650328","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9650328","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of medical research","raw_type":"Clinical Trial"},{"id":"mag:25904378","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9650328","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2279419638","https://openalex.org/W2055895517","https://openalex.org/W2062618442","https://openalex.org/W2072985846","https://openalex.org/W2403251236","https://openalex.org/W1032473475","https://openalex.org/W2022739472","https://openalex.org/W2415682698","https://openalex.org/W2102266003","https://openalex.org/W2403369066"],"abstract_inverted_index":{"BACKGROUND:":[0],"A":[1],"study":[2],"was":[3,63,72,80,157,197,205],"designed":[4],"to":[5,239],"evaluate":[6],"the":[7,83,121,142,190],"effect":[8],"of":[9,19,41,44,49,61,68,105,153,162,218,245],"acarbose":[10,62,124,156,196,235],"and":[11,29,77,88,107,110,129,161,174,183,201,223,229,248],"Plantago":[12],"psyllium":[13,70,132,204,215,238],"mucilage":[14,71],"on":[15,53],"glycemic":[16,243],"index":[17,112,176,194,226,244],"(GI)":[18],"bread.":[20],"METHODS:":[21],"Twelve":[22],"patients":[23,222],"with":[24,38,123,130,189,195,202],"non-insulin-dependent":[25],"diabetes":[26],"mellitus":[27],"(NIDDM)":[28],"ten":[30],"healthy":[31,180,231],"volunteers":[32],"were":[33,51,91,113,137],"studied.":[34],"Three":[35],"meal":[36],"tests":[37],"an":[39],"intake":[40],"90":[42],"g":[43,48,67],"white":[45],"bread":[46,79,154,163,219],"(50":[47],"carbohydrates)":[50],"performed":[52],"each":[54],"subject.":[55],"In":[56,116,179],"one":[57],"test,":[58,76],"200":[59],"mg":[60],"given,":[64],"while":[65],"15":[66,208],"P.":[69,131,165,203,214,237],"given":[73],"in":[74,82,120,141,220,227,230],"another":[75],"only":[78],"ingested":[81],"control":[84,143],"test.":[85],"Serum":[86],"glucose":[87,106],"insulin":[89],"concentrations":[90,104],"measured":[92],"every":[93],"30":[94],"min":[95],"from":[96],"0-180":[97],"min.":[98],"Net":[99],"area":[100],"under":[101],"curve":[102],"(AUC)":[103],"insulin,":[108],"GI":[109,152,184,217],"insulinic":[111,175,193,225],"calculated.":[114],"RESULTS:":[115],"NIDDM":[117,221,228],"patients,":[118],"AUC-glucose":[119,182],"test":[122,144],"(1.9":[125],"+/-":[126,134,146,159,168,199,207],"0.7":[127],"mmol/L)":[128,136,148],"(4.3":[133],"1.2":[135],"significantly":[138,187],"lower":[139],"than":[140],"(7.4":[145],"1.5":[147],"(p":[149,170,209],"<":[150,171,210],"0.01).":[151],"plus":[155,164],"26":[158],"13,":[160],"psyllium,":[166],"59":[167],"10":[169],"0.05).":[172,211],"AUC-insulin":[173],"behave":[177],"similarly.":[178],"individuals,":[181],"did":[185],"not":[186],"change":[188],"treatments;":[191],"however,":[192],"17":[198],"16,":[200],"68":[206],"Acarbose":[212],"or":[213,236],"decreased":[216],"diminished":[224],"subjects.":[232],"CONCLUSIONS:":[233],"Adding":[234],"meals":[240],"may":[241,249],"reduce":[242],"carbohydrate":[246],"foods":[247],"help":[250],"diabetic":[251],"control.":[252]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}