{"id":"https://openalex.org/W2590422232","doi":"https://doi.org/10.1016/s0140-6736(17)30441-5","title":"Cooperativity of streptococcal surface proteins in binding platelets and extracellular matrix","display_name":"Cooperativity of streptococcal surface proteins in binding platelets and extracellular matrix","publication_year":2017,"publication_date":"2017-02-01","ids":{"openalex":"https://openalex.org/W2590422232","doi":"https://doi.org/10.1016/s0140-6736(17)30441-5","mag":"2590422232"},"language":"en","primary_location":{"id":"doi:10.1016/s0140-6736(17)30441-5","doi":"https://doi.org/10.1016/s0140-6736(17)30441-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0140-6736(17)30441-5","pdf_url":null,"source":{"id":"https://openalex.org/S49861241","display_name":"The Lancet","issn_l":"0099-5355","issn":["0099-5355","0140-6736","1474-547X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://research-information.bris.ac.uk/en/publications/66758c58-e9f4-4bc7-800f-226db369e85f","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067616610","display_name":"Jennifer Haworth","orcid":"https://orcid.org/0000-0002-3096-6717","observed_orcids":["https://orcid.org/0000-0002-3096-6717"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Jennifer Haworth","raw_affiliation_strings":["University of Bristol, Bristol, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036602050","display_name":"Howard F. Jenkinson","orcid":"https://orcid.org/0000-0002-9195-7945","observed_orcids":["https://orcid.org/0000-0002-9195-7945"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Howard Jenkinson","raw_affiliation_strings":["University of Bristol, Bristol, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109179592","display_name":"Steve W. Kerrigan","orcid":"https://orcid.org/0000-0001-8945-5703","observed_orcids":["https://orcid.org/0000-0001-8945-5703"]},"institutions":[{"id":"https://openalex.org/I142762351","display_name":"Royal College of Surgeons in Ireland","ror":"https://ror.org/01hxy9878","country_code":"IE","type":"education","lineage":["https://openalex.org/I142762351"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Steve Kerrigan","raw_affiliation_strings":["Royal College of Surgeons in Ireland, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Royal College of Surgeons in Ireland, Dublin, Ireland","institution_ids":["https://openalex.org/I142762351"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073737255","display_name":"Jane L. Brittan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jane Brittan","raw_affiliation_strings":["University of Bristol, Bristol, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061346123","display_name":"Angela H. Nobbs","orcid":"https://orcid.org/0000-0003-3813-4410","observed_orcids":["https://orcid.org/0000-0003-3813-4410"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Angela Nobbs","raw_affiliation_strings":["University of Bristol, Bristol, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5067616610"],"corresponding_institution_ids":["https://openalex.org/I36234482"],"apc_list":{"value":7890,"currency":"USD","value_usd":7890},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.02090085,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"389","issue":null,"first_page":"S45","last_page":"S45"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11551","display_name":"Infective Endocarditis Diagnosis and Management","score":0.5990999937057495,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11551","display_name":"Infective Endocarditis Diagnosis and Management","score":0.5990999937057495,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.22190000116825104,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.08389999717473984,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/streptococcus-gordonii","display_name":"Streptococcus gordonii","score":1.0},{"id":"https://openalex.org/keywords/pada","display_name":"pada","score":0.9589999914169312},{"id":"https://openalex.org/keywords/hsa","display_name":"HSA","score":0.9819999933242798},{"id":"https://openalex.org/keywords/platelet-adhesion","display_name":"platelet adhesion","score":0.8069999814033508},{"id":"https://openalex.org/keywords/extracellular-matrix-binding","display_name":"extracellular matrix binding","score":0.8309999704360962},{"id":"https://openalex.org/keywords/vitronectin","display_name":"vitronectin","score":0.8679999709129333},{"id":"https://openalex.org/keywords/fibronectin","display_name":"fibronectin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/infective-endocarditis","display_name":"infective endocarditis","score":0.8050000071525574},{"id":"https://openalex.org/keywords/bacterial-virulence","display_name":"bacterial virulence","score":0.7409999966621399},{"id":"https://openalex.org/keywords/bacterial-adhesion","display_name":"bacterial adhesion","score":0.44699999690055847},{"id":"https://openalex.org/keywords/oral-bacteria","display_name":"oral bacteria","score":0.5120000243186951}],"concepts":[{"id":"https://openalex.org/C164144092","wikidata":"https://www.wikidata.org/wiki/Q6587033","display_name":"Vitronectin","level":4,"score":0.8940078020095825},{"id":"https://openalex.org/C2780368718","wikidata":"https://www.wikidata.org/wiki/Q7623352","display_name":"Streptococcus gordonii","level":4,"score":0.771073579788208},{"id":"https://openalex.org/C86492073","wikidata":"https://www.wikidata.org/wiki/Q413766","display_name":"Fibronectin","level":3,"score":0.6832686066627502},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.6531333923339844},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.60691899061203},{"id":"https://openalex.org/C167814343","wikidata":"https://www.wikidata.org/wiki/Q419341","display_name":"Thrombospondin","level":4,"score":0.5770150423049927},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5189387798309326},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.514590859413147},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.501162052154541},{"id":"https://openalex.org/C188082640","wikidata":"https://www.wikidata.org/wiki/Q1780899","display_name":"Complementation","level":4,"score":0.4673747420310974},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.4330558776855469},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.360743910074234},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.329079806804657},{"id":"https://openalex.org/C2778663903","wikidata":"https://www.wikidata.org/wiki/Q140018","display_name":"Streptococcaceae","level":3,"score":0.12564441561698914},{"id":"https://openalex.org/C55728118","wikidata":"https://www.wikidata.org/wiki/Q425402","display_name":"Metalloproteinase","level":3,"score":0.12423333525657654},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0904889702796936},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07711586356163025},{"id":"https://openalex.org/C109523444","wikidata":"https://www.wikidata.org/wiki/Q424216","display_name":"Matrix metalloproteinase","level":2,"score":0.06529214978218079},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/s0140-6736(17)30441-5","doi":"https://doi.org/10.1016/s0140-6736(17)30441-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0140-6736(17)30441-5","pdf_url":null,"source":{"id":"https://openalex.org/S49861241","display_name":"The Lancet","issn_l":"0099-5355","issn":["0099-5355","0140-6736","1474-547X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet","raw_type":"journal-article"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire/66758c58-e9f4-4bc7-800f-226db369e85f","doi":null,"is_oa":true,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/66758c58-e9f4-4bc7-800f-226db369e85f","pdf_url":null,"source":{"id":"https://openalex.org/S4306400895","display_name":"Bristol Research (University of Bristol)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I36234482","host_organization_name":"University of Bristol","host_organization_lineage":["https://openalex.org/I36234482"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Haworth, J, Jenkinson, H, Kerrigan, S, Brittan, J & Nobbs, A 2017, 'Cooperativity of streptococcal surface proteins in binding platelets and extracellular matrix : Spring Meeting for Clinician Scientists in Training 2017', Lancet, vol. 389, Supplement 1, pp. S45. https://doi.org/10.1016/S0140-6736(17)30441-5","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"pmh:oai:research-information.bris.ac.uk:openaire/66758c58-e9f4-4bc7-800f-226db369e85f","doi":null,"is_oa":true,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/66758c58-e9f4-4bc7-800f-226db369e85f","pdf_url":null,"source":{"id":"https://openalex.org/S4306400895","display_name":"Bristol Research (University of Bristol)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I36234482","host_organization_name":"University of Bristol","host_organization_lineage":["https://openalex.org/I36234482"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Haworth, J, Jenkinson, H, Kerrigan, S, Brittan, J & Nobbs, A 2017, 'Cooperativity of streptococcal surface proteins in binding platelets and extracellular matrix : Spring Meeting for Clinician Scientists in Training 2017', Lancet, vol. 389, Supplement 1, pp. S45. https://doi.org/10.1016/S0140-6736(17)30441-5","raw_type":"info:eu-repo/semantics/publishedVersion"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2520248333","https://openalex.org/W2038929411","https://openalex.org/W2138162801","https://openalex.org/W7221563818","https://openalex.org/W1503021916","https://openalex.org/W2115585275","https://openalex.org/W2119186634","https://openalex.org/W2017171638","https://openalex.org/W2562823974","https://openalex.org/W2059645430"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2017-03-03T00:00:00"}