{"id":"https://openalex.org/W2590218713","doi":"https://doi.org/10.1097/mca.0000000000000480","title":"Impact of chronic statin therapy on clinical presentation and underlying lesion morphology in patients undergoing percutaneous intervention: an ADAPT-DES IVUS substudy","display_name":"Impact of chronic statin therapy on clinical presentation and underlying lesion morphology in patients undergoing percutaneous intervention: an ADAPT-DES IVUS substudy","publication_year":2017,"publication_date":"2017-02-25","ids":{"openalex":"https://openalex.org/W2590218713","doi":"https://doi.org/10.1097/mca.0000000000000480","mag":"2590218713","pmid":"https://pubmed.ncbi.nlm.nih.gov/28240675"},"language":"en","primary_location":{"id":"doi:10.1097/mca.0000000000000480","doi":"https://doi.org/10.1097/mca.0000000000000480","is_oa":false,"landing_page_url":"https://doi.org/10.1097/mca.0000000000000480","pdf_url":null,"source":{"id":"https://openalex.org/S31433238","display_name":"Coronary Artery Disease","issn_l":"0954-6928","issn":["0954-6928","1473-5830"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Coronary Artery Disease","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030554342","display_name":"Tadayuki Kadohira","orcid":"https://orcid.org/0000-0002-7323-7004","observed_orcids":["https://orcid.org/0000-0002-7323-7004"]},"institutions":[{"id":"https://openalex.org/I1313334418","display_name":"Cone Health","ror":"https://ror.org/03jeg4p28","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1313334418"]},{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I1340179700","display_name":"NewYork\u2013Presbyterian Hospital","ror":"https://ror.org/03gzbrs57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I2801962034","display_name":"Shaare Zedek Medical Center","ror":"https://ror.org/04d0szq68","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2801962034"]},{"id":"https://openalex.org/I2802841970","display_name":"The Ohio State University Wexner Medical Center","ror":"https://ror.org/00c01js51","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802841970"]},{"id":"https://openalex.org/I2802879425","display_name":"Bikur Cholim Hospital","ror":"https://ror.org/03zpnb459","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2802879425"]},{"id":"https://openalex.org/I4210136666","display_name":"FirstHealth of the Carolinas","ror":"https://ror.org/03qc4hj53","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210136666"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["BR","IL","US"],"is_corresponding":false,"raw_author_name":"Tadayuki Kadohira","raw_affiliation_strings":["aClinical Trials Center,Cardiovascular Research Foundation bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York cWellmont CVA Heart Institute, Kingsport, Tennessee dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte eReid Heart Center, FirstHealth of the Carolinas, Pinehurst fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA hShaare Zedek Medical Center, Jerusalem, Israel iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil jHelios Amper-Klinikum, Dachau, Germany","Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"aClinical Trials Center,Cardiovascular Research Foundation bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York cWellmont CVA Heart Institute, Kingsport, Tennessee dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte eReid Heart Center, FirstHealth of the Carolinas, Pinehurst fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA hShaare Zedek Medical Center, Jerusalem, Israel iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1313334418","https://openalex.org/I1334069289","https://openalex.org/I1340179700","https://openalex.org/I17974374","https://openalex.org/I2799503643","https://openalex.org/I2801962034","https://openalex.org/I2802841970","https://openalex.org/I2802879425","https://openalex.org/I4210136666","https://openalex.org/I4210144653","https://openalex.org/I52357470"]},{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002654097","display_name":"Gary S. Mintz","orcid":"https://orcid.org/0000-0003-3296-8705","observed_orcids":["https://orcid.org/0000-0003-3296-8705"]},"institutions":[{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary S. Mintz","raw_affiliation_strings":["Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070999274","display_name":"Cristiano Freitas de Souza","orcid":"https://orcid.org/0000-0001-9800-8665","observed_orcids":["https://orcid.org/0000-0001-9800-8665"]},"institutions":[{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cristiano F. Souza","raw_affiliation_strings":["Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005336546","display_name":"Bernhard Witzenbichler","orcid":"https://orcid.org/0000-0001-9322-1926","observed_orcids":["https://orcid.org/0000-0001-9322-1926"]},"institutions":[{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bernhard Witzenbichler","raw_affiliation_strings":["Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113897936","display_name":"David Christopher Metzger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. Christopher Metzger","raw_affiliation_strings":["Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103736873","display_name":"Michael J. Rinaldi","orcid":"https://orcid.org/0009-0005-7931-185X","observed_orcids":["https://orcid.org/0009-0005-7931-185X"]},"institutions":[{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael J. Rinaldi","raw_affiliation_strings":["Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090736450","display_name":"Ernest L. Mazzaferri","orcid":"https://orcid.org/0000-0002-5532-0306","observed_orcids":["https://orcid.org/0000-0002-5532-0306"]},"institutions":[{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ernest L. Mazzaferri","raw_affiliation_strings":["Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050982232","display_name":"Peter L. Duffy","orcid":"https://orcid.org/0000-0001-8760-9879","observed_orcids":["https://orcid.org/0000-0001-8760-9879"]},"institutions":[{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter L. Duffy","raw_affiliation_strings":["Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040379719","display_name":"Giora Weisz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Giora Weisz","raw_affiliation_strings":["Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052557057","display_name":"Thomas Stuckey","orcid":"https://orcid.org/0000-0002-5088-8277","observed_orcids":["https://orcid.org/0000-0002-5088-8277"]},"institutions":[{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas D. Stuckey","raw_affiliation_strings":["Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074206747","display_name":"Bruce R. Brodie","orcid":"https://orcid.org/0000-0002-6000-4148","observed_orcids":["https://orcid.org/0000-0002-6000-4148"]},"institutions":[{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruce R. Brodie","raw_affiliation_strings":["Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060412536","display_name":"Aaron Crowley","orcid":"https://orcid.org/0000-0002-1203-9223","observed_orcids":["https://orcid.org/0000-0002-1203-9223"]},"institutions":[{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aaron Crowley","raw_affiliation_strings":["Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058875978","display_name":"Ajay Jayant Kirtane","orcid":"https://orcid.org/0000-0003-0061-1058","observed_orcids":["https://orcid.org/0000-0003-0061-1058"]},"institutions":[{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ajay J. Kirtane","raw_affiliation_strings":["Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046629853","display_name":"Gregg W. Stone","orcid":"https://orcid.org/0000-0002-3416-8210","observed_orcids":["https://orcid.org/0000-0002-3416-8210"]},"institutions":[{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregg W. Stone","raw_affiliation_strings":["Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082883917","display_name":"Akiko Maehara","orcid":"https://orcid.org/0000-0002-1910-8447","observed_orcids":["https://orcid.org/0000-0002-1910-8447"]},"institutions":[{"id":"https://openalex.org/I1334069289","display_name":"Carolinas Healthcare System","ror":"https://ror.org/0594s0e67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334069289"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4210144653","display_name":"Cardiovascular Research Foundation","ror":"https://ror.org/04yxwc698","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210144653"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Akiko Maehara","raw_affiliation_strings":["to Akiko Maehara, MD, Clinical Trials Center, Cardiovascular Research Foundation, 1700 Broadway, New York, NY 10019, USA Tel: +1 646 434 4569; fax: +1 646 434 4464; e-mail: [email\u00a0protected]","Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"to Akiko Maehara, MD, Clinical Trials Center, Cardiovascular Research Foundation, 1700 Broadway, New York, NY 10019, USA Tel: +1 646 434 4569; fax: +1 646 434 4464; e-mail: [email\u00a0protected]","institution_ids":["https://openalex.org/I4210144653"]},{"raw_affiliation_string":"Accepted February 8, 2017; Received November 14, 2016; Received in revised form January 25, 2017; aClinical Trials Center,Cardiovascular Research Foundation; bNew York-Presbyterian Hospital/Columbia University Medical Center, NewYork, New York; cWellmont CVA Heart Institute, Kingsport, Tennessee; dSanger Heart & Vascular Institute/Carolinas HealthCare System, Charlotte; e-mail: [email\u00a0protected]; eReid Heart Center, FirstHealth of the Carolinas, Pinehurst; fLeBauer-Brodie Center for Cardiovascular Research and Education/Cone Health, Greensboro, North Carolina; fax: +1 646 434 4464; gThe Ohio State University Wexner Medical Center, Columbus, Ohio, USA; hShaare Zedek Medical Center, Jerusalem, Israel; iFederal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil; jHelios Amper-Klinikum, Dachau, Germany","institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5082883917"],"corresponding_institution_ids":["https://openalex.org/I1334069289","https://openalex.org/I2799503643","https://openalex.org/I4210144653"],"apc_list":null,"apc_paid":null,"fwci":0.8325,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.74801383,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"28","issue":"3","first_page":"218","last_page":"224"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/percutaneous-coronary-intervention","display_name":"percutaneous coronary intervention","score":0.8600000143051147},{"id":"https://openalex.org/keywords/plaque-morphology","display_name":"plaque morphology","score":0.7409999966621399},{"id":"https://openalex.org/keywords/plaque-composition","display_name":"plaque composition","score":0.8510000109672546},{"id":"https://openalex.org/keywords/virtual-histology-intravascular-ultrasound","display_name":"virtual histology intravascular ultrasound","score":0.9449999928474426},{"id":"https://openalex.org/keywords/thin-cap-fibroatheroma","display_name":"thin-cap fibroatheroma","score":0.8209999799728394},{"id":"https://openalex.org/keywords/plaque-rupture","display_name":"plaque rupture","score":0.9309999942779541},{"id":"https://openalex.org/keywords/coronary-artery-calcification","display_name":"coronary artery calcification","score":0.5870000123977661},{"id":"https://openalex.org/keywords/plaque-burden","display_name":"plaque burden","score":0.6169999837875366},{"id":"https://openalex.org/keywords/clinical-characteristics","display_name":"clinical features","score":0.5809999704360962},{"id":"https://openalex.org/keywords/stable-angina","display_name":"stable angina","score":0.7609999775886536},{"id":"https://openalex.org/keywords/acute-myocardial-infarction","display_name":"acute myocardial infarction","score":0.984000027179718},{"id":"https://openalex.org/keywords/dual-antiplatelet-therapy","display_name":"dual antiplatelet therapy","score":0.7749999761581421},{"id":"https://openalex.org/keywords/drug-eluting-stents","display_name":"drug-eluting stents","score":0.9940000176429749}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.96552574634552},{"id":"https://openalex.org/C2780400711","wikidata":"https://www.wikidata.org/wiki/Q2008344","display_name":"Percutaneous coronary intervention","level":3,"score":0.8034745454788208},{"id":"https://openalex.org/C45393284","wikidata":"https://www.wikidata.org/wiki/Q191012","display_name":"Conventional PCI","level":3,"score":0.6993697285652161},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6643903851509094},{"id":"https://openalex.org/C2776839432","wikidata":"https://www.wikidata.org/wiki/Q954845","display_name":"Statin","level":2,"score":0.6212294697761536},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5850979089736938},{"id":"https://openalex.org/C2776931568","wikidata":"https://www.wikidata.org/wiki/Q1671577","display_name":"Intravascular ultrasound","level":2,"score":0.5796341896057129},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.5208178758621216},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.5129508376121521},{"id":"https://openalex.org/C2778826181","wikidata":"https://www.wikidata.org/wiki/Q3310538","display_name":"Culprit","level":3,"score":0.43174609541893005}],"mesh":[{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005355","descriptor_name":"Fibrosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012422","descriptor_name":"Rupture, Spontaneous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015999","descriptor_name":"Multivariate Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016009","descriptor_name":"Chi-Square Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017023","descriptor_name":"Coronary Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018084","descriptor_name":"Ultrasonography, Interventional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019161","descriptor_name":"Hydroxymethylglutaryl-CoA Reductase Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D057216","descriptor_name":"Propensity Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058226","descriptor_name":"Plaque, Atherosclerotic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D061205","descriptor_name":"Vascular Calcification","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D061205","descriptor_name":"Vascular Calcification","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D061205","descriptor_name":"Vascular Calcification","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D062645","descriptor_name":"Percutaneous Coronary Intervention","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/mca.0000000000000480","doi":"https://doi.org/10.1097/mca.0000000000000480","is_oa":false,"landing_page_url":"https://doi.org/10.1097/mca.0000000000000480","pdf_url":null,"source":{"id":"https://openalex.org/S31433238","display_name":"Coronary Artery Disease","issn_l":"0954-6928","issn":["0954-6928","1473-5830"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Coronary Artery Disease","raw_type":"journal-article"},{"id":"pmid:28240675","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28240675","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Coronary artery disease","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W110324665","https://openalex.org/W1963913523","https://openalex.org/W1986631172","https://openalex.org/W2018637416","https://openalex.org/W2039565394","https://openalex.org/W2054506834","https://openalex.org/W2058125218","https://openalex.org/W2079289240","https://openalex.org/W2080538223","https://openalex.org/W2114646598","https://openalex.org/W2127032164","https://openalex.org/W2128596140","https://openalex.org/W2146228563","https://openalex.org/W2148757918","https://openalex.org/W2157857368","https://openalex.org/W2161785946","https://openalex.org/W2166910397","https://openalex.org/W2195660903"],"related_works":["https://openalex.org/W2050905776","https://openalex.org/W2120999530","https://openalex.org/W2117093946","https://openalex.org/W2050033156","https://openalex.org/W1947868419","https://openalex.org/W2054979363","https://openalex.org/W110849523","https://openalex.org/W2089545878","https://openalex.org/W7097722152","https://openalex.org/W2131763688"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Previous":[1],"intravascular":[2],"ultrasound":[3],"(IVUS)":[4],"studies":[5],"have":[6],"not":[7,55],"established":[8],"a":[9,64,112,150,186],"relationship":[10],"between":[11],"chronic":[12,47,101],"statin":[13,48,102,208],"use":[14,30,209],"and":[15,18,33,41,60,80,90,110,140,201,203,223,234,237],"plaque":[16,39,152,179,235],"morphology":[17,40],"composition":[19,42],"in":[20,43,84,146,190,210],"patients":[21,44,52,86,97,107,120,131,148,159,211],"undergoing":[22],"percutaneous":[23],"coronary":[24,116,213],"intervention":[25],"(PCI).":[26],"We":[27],"sought":[28],"to":[29,37,124],"pre-PCI":[31,78],"grayscale":[32,79,202],"virtual":[34],"histology":[35],"(VH)-IVUS":[36],"assess":[38],"treated":[45,99],"with":[46,51,74,87,100,126,135,212,218,227],"therapy":[49,103],"compared":[50],"who":[53],"were":[54,82,98,108,121,195],"taking":[56],"statins":[57],"before":[58,104],"admission":[59],"PCI.":[61],"METHODS:":[62],"In":[63,185],"prespecified":[65],"substudy":[66],"of":[67,70,115],"the":[68],"Assessment":[69],"Dual":[71],"AntiPlatelet":[72],"Therapy":[73],"Drug-Eluting":[75],"Stents":[76],"study,":[77],"VH-IVUS":[81,141,204],"performed":[83],"780":[85],"916":[88],"culprit":[89],"765":[91],"nonculprit":[92],"lesions.":[93],"RESULTS:":[94],"Overall,":[95],"338":[96],"admission.":[105],"Statin-treated":[106,119,158],"older":[109],"had":[111,149,160],"higher":[113],"prevalence":[114],"risk":[117],"factors.":[118],"more":[122,132,155,161,219,238],"likely":[123],"present":[125],"stable":[127,220],"angina,":[128],"whereas":[129],"non-statin-treated":[130],"frequently":[133],"presented":[134],"acute":[136],"myocardial":[137],"infarction.":[138],"Grayscale":[139],"findings":[142,225],"showed":[143],"that":[144],"lesions":[145],"statin-treated":[147],"smaller":[151],"burden,":[153],"but":[154,169],"dense":[156],"calcium.":[157],"calcified":[162,239],"thick-cap":[163,240],"fibroatheromas":[164,173,233],"(9.2":[165],"vs.":[166,175,182],"3.7%,":[167],"P=0.0007),":[168],"fewer":[170],"VH-defined":[171],"thin-cap":[172],"(45.2":[174],"56.1%,":[176],"P=0.001)":[177],"or":[178],"ruptures":[180,236],"(26.6":[181],"38.4%,":[183],"P=0.0001).":[184],"propensity-matched":[187],"population":[188],"(n=249":[189],"each":[191],"group),":[192],"similar":[193],"results":[194],"obtained":[196],"as":[197],"regards":[198],"clinical":[199,221],"presentation":[200,222],"findings.":[205],"CONCLUSION:":[206],"Chronic":[207],"artery":[214],"disease":[215],"was":[216],"associated":[217],"IVUS":[224],"consistent":[226],"greater":[228],"lesion":[229],"stability":[230],"(fewer":[231],"VH-thin-cap":[232],"fibroatheromas).":[241]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2017-03-03T00:00:00"}