{"id":"https://openalex.org/W2589618062","doi":"https://doi.org/10.3389/fneur.2017.00063","title":"Sleep Disorders: Is the Trigemino-Cardiac Reflex a Missing Link?","display_name":"Sleep Disorders: Is the Trigemino-Cardiac Reflex a Missing Link?","publication_year":2017,"publication_date":"2017-02-27","ids":{"openalex":"https://openalex.org/W2589618062","doi":"https://doi.org/10.3389/fneur.2017.00063","mag":"2589618062","pmid":"https://pubmed.ncbi.nlm.nih.gov/28289401","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5326750"},"language":"en","primary_location":{"id":"doi:10.3389/fneur.2017.00063","doi":"https://doi.org/10.3389/fneur.2017.00063","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2017.00063","pdf_url":"https://www.frontiersin.org/articles/10.3389/fneur.2017.00063/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2589618062"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fneur.2017.00063/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041407465","display_name":"Tumul Chowdhury","orcid":"https://orcid.org/0000-0002-8946-4148","observed_orcids":["https://orcid.org/0000-0002-8946-4148"]},"institutions":[{"id":"https://openalex.org/I46247651","display_name":"University of Manitoba","ror":"https://ror.org/02gfys938","country_code":"CA","type":"education","lineage":["https://openalex.org/I46247651"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Tumul Chowdhury","raw_affiliation_strings":["Department of Anesthesiology and Perioperative Medicine, University of Manitoba, Winnipeg, MB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Perioperative Medicine, University of Manitoba, Winnipeg, MB, Canada","institution_ids":["https://openalex.org/I46247651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086926050","display_name":"Barkha Bindu","orcid":"https://orcid.org/0000-0003-0016-7030","observed_orcids":["https://orcid.org/0000-0003-0016-7030"]},"institutions":[{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Barkha Bindu","raw_affiliation_strings":["Department of Neuro-anaesthesiology and Critical Care, All India Institute of Medical Sciences, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuro-anaesthesiology and Critical Care, All India Institute of Medical Sciences, New Delhi, India","institution_ids":["https://openalex.org/I63739035"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033473907","display_name":"Gyaninder Pal Singh","orcid":"https://orcid.org/0000-0002-6702-6892","observed_orcids":["https://orcid.org/0000-0002-6702-6892"]},"institutions":[{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Gyaninder Pal Singh","raw_affiliation_strings":["Department of Neuro-anaesthesiology and Critical Care, All India Institute of Medical Sciences, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuro-anaesthesiology and Critical Care, All India Institute of Medical Sciences, New Delhi, India","institution_ids":["https://openalex.org/I63739035"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073128244","display_name":"Bernhard J. Schaller","orcid":"https://orcid.org/0000-0002-7710-8090","observed_orcids":["https://orcid.org/0000-0002-7710-8090"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Bernhard Schaller","raw_affiliation_strings":["Department of Research, University of Southampton, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Research, University of Southampton, Southampton, UK","institution_ids":["https://openalex.org/I43439940"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5041407465"],"corresponding_institution_ids":["https://openalex.org/I46247651"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.4062,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.33842628,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"8","issue":null,"first_page":"63","last_page":"63"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.8080999851226807,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.8080999851226807,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.16110000014305115,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.013299999758601189,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trigeminocardiac-reflex","display_name":"trigeminocardiac reflex","score":0.9980000257492065},{"id":"https://openalex.org/keywords/sleep-disturbance","display_name":"sleep disorders","score":0.8799999952316284},{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"obstructive sleep apnea","score":0.9610000252723694},{"id":"https://openalex.org/keywords/bruxism","display_name":"bruxism","score":0.9940000176429749},{"id":"https://openalex.org/keywords/diving-reflex","display_name":"diving reflex","score":0.9089999794960022},{"id":"https://openalex.org/keywords/sudden-infant-death-syndrome","display_name":"sudden infant death syndrome","score":0.9570000171661377},{"id":"https://openalex.org/keywords/trigeminal-innervation","display_name":"trigeminal innervation","score":0.7590000033378601},{"id":"https://openalex.org/keywords/bradycardia","display_name":"bradycardia","score":0.753000020980835},{"id":"https://openalex.org/keywords/cardiac-arrhythmia","display_name":"cardiac arrhythmias","score":0.8059999942779541},{"id":"https://openalex.org/keywords/neurosurgery","display_name":"neurosurgery","score":0.5720000267028809},{"id":"https://openalex.org/keywords/skull-base-surgery","display_name":"skull base surgery","score":0.9950000047683716}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6991657614707947},{"id":"https://openalex.org/C83974742","wikidata":"https://www.wikidata.org/wiki/Q179405","display_name":"Reflex","level":2,"score":0.6607014536857605},{"id":"https://openalex.org/C2777495988","wikidata":"https://www.wikidata.org/wiki/Q217111","display_name":"Bradycardia","level":4,"score":0.6578171253204346},{"id":"https://openalex.org/C2781326671","wikidata":"https://www.wikidata.org/wiki/Q754424","display_name":"Apnea","level":2,"score":0.6008639335632324},{"id":"https://openalex.org/C2777935920","wikidata":"https://www.wikidata.org/wiki/Q213600","display_name":"Sleep apnea","level":2,"score":0.5671190023422241},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.547174870967865},{"id":"https://openalex.org/C117437137","wikidata":"https://www.wikidata.org/wiki/Q5038720","display_name":"Cardiorespiratory fitness","level":2,"score":0.47245052456855774},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.4696691930294037},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.45387449860572815},{"id":"https://openalex.org/C2777397368","wikidata":"https://www.wikidata.org/wiki/Q189763","display_name":"Trigeminal nerve","level":2,"score":0.4243905544281006},{"id":"https://openalex.org/C2987955292","wikidata":"https://www.wikidata.org/wiki/Q161801","display_name":"Sudden infant death syndrome","level":2,"score":0.41267508268356323},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2197267711162567},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.19754904508590698},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.18760913610458374},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.08160588145256042},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fneur.2017.00063","doi":"https://doi.org/10.3389/fneur.2017.00063","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2017.00063","pdf_url":"https://www.frontiersin.org/articles/10.3389/fneur.2017.00063/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4199126","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5326750","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:28289401","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28289401","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in neurology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5326750","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5326750/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Neurol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3389/fneur.2017.00063","doi":"https://doi.org/10.3389/fneur.2017.00063","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2017.00063","pdf_url":"https://www.frontiersin.org/articles/10.3389/fneur.2017.00063/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2589618062.pdf","grobid_xml":"https://content.openalex.org/works/W2589618062.grobid-xml"},"referenced_works_count":70,"referenced_works":["https://openalex.org/W33312169","https://openalex.org/W87334503","https://openalex.org/W109096715","https://openalex.org/W118661420","https://openalex.org/W142394464","https://openalex.org/W194373269","https://openalex.org/W244799260","https://openalex.org/W246203836","https://openalex.org/W1485196502","https://openalex.org/W1511018445","https://openalex.org/W1519232679","https://openalex.org/W1714259827","https://openalex.org/W1726343988","https://openalex.org/W1965328764","https://openalex.org/W1968979897","https://openalex.org/W1970044545","https://openalex.org/W1970621674","https://openalex.org/W1975845088","https://openalex.org/W1976882776","https://openalex.org/W1988895386","https://openalex.org/W1993974635","https://openalex.org/W2002880173","https://openalex.org/W2005565772","https://openalex.org/W2006432804","https://openalex.org/W2013524245","https://openalex.org/W2027811581","https://openalex.org/W2031349309","https://openalex.org/W2034556696","https://openalex.org/W2038542634","https://openalex.org/W2046019168","https://openalex.org/W2046617967","https://openalex.org/W2049465232","https://openalex.org/W2050724245","https://openalex.org/W2056301776","https://openalex.org/W2079126475","https://openalex.org/W2080819462","https://openalex.org/W2088026107","https://openalex.org/W2091451778","https://openalex.org/W2093671121","https://openalex.org/W2100750133","https://openalex.org/W2103033262","https://openalex.org/W2105727933","https://openalex.org/W2117778982","https://openalex.org/W2120367088","https://openalex.org/W2130660308","https://openalex.org/W2133222386","https://openalex.org/W2140058549","https://openalex.org/W2145451287","https://openalex.org/W2145776851","https://openalex.org/W2148345618","https://openalex.org/W2152395006","https://openalex.org/W2163166459","https://openalex.org/W2164101317","https://openalex.org/W2166275592","https://openalex.org/W2203139301","https://openalex.org/W2235280992","https://openalex.org/W2265045123","https://openalex.org/W2313075128","https://openalex.org/W2316139099","https://openalex.org/W2319610868","https://openalex.org/W2335424338","https://openalex.org/W2389957666","https://openalex.org/W2404089258","https://openalex.org/W2409285038","https://openalex.org/W2419621573","https://openalex.org/W2441738042","https://openalex.org/W2481821582","https://openalex.org/W2501903838","https://openalex.org/W2557869483","https://openalex.org/W2614781785"],"related_works":["https://openalex.org/W2882999727","https://openalex.org/W4400657894","https://openalex.org/W2783305905","https://openalex.org/W2892834605","https://openalex.org/W2611570579","https://openalex.org/W2006804902","https://openalex.org/W2505045741","https://openalex.org/W4254448681","https://openalex.org/W2182886239","https://openalex.org/W1977429950"],"abstract_inverted_index":{"Trigeminal":[0],"innervated":[1],"areas":[2],"in":[3,41,46,57,80,115],"face,":[4],"nasolacrimal,":[5],"and":[6,23,100,111],"nasal":[7],"mucosa":[8],"can":[9],"produce":[10],"a":[11,28,72],"wide":[12],"array":[13],"of":[14,37,69,74,113],"cardiorespiratory":[15],"manifestations":[16],"that":[17],"include":[18],"apnea,":[19,95],"bradypnea,":[20],"bradycardia,":[21],"hypotension,":[22],"arrhythmias.":[24],"This":[25],"reflex":[26],"is":[27,39,97],"well-known":[29],"entity":[30],"called":[31],"\"trigemino-cardiac":[32],"reflex\"":[33],"(TCR).":[34],"The":[35,85],"role":[36,68,110],"TCR":[38,114],"investigated":[40,79],"various":[42,58],"pathophysiological":[43],"conditions":[44],"especially":[45],"neurosurgical,":[47],"but":[48],"also":[49,62],"skull":[50],"base":[51],"surgery":[52],"procedures.":[53],"Additionally,":[54],"its":[55],"significance":[56],"sleep-related":[59],"disorders":[60,91],"has":[61,76],"been":[63,77],"highlighted":[64],"recently.":[65],"Though,":[66],"the":[67,108],"diving":[70],"reflex,":[71],"subtype":[73],"TCR,":[75],"extensively":[78],"sudden":[81],"infant":[82],"death":[83],"syndrome.":[84],"data":[86],"related":[87],"to":[88,106],"other":[89],"sleep":[90,94,118],"including":[92],"obstructive":[93],"bruxism":[96],"very":[98],"limited":[99],"thus,":[101],"this":[102],"mini":[103],"review":[104],"aims":[105],"investigate":[107],"possible":[109],"correlation":[112],"causing":[116],"such":[117],"abnormalities.":[119]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":4}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2017-03-03T00:00:00"}