{"id":"https://openalex.org/W2587701055","doi":null,"title":"Health and imaging outcomes in axial spondyloarthritis","display_name":"Health and imaging outcomes in axial spondyloarthritis","publication_year":2016,"publication_date":"2016-10-18","ids":{"openalex":"https://openalex.org/W2587701055","mag":"2587701055"},"language":"en","primary_location":{"id":"pmh:oai:alma.31UKB_LEU:9940741356902711","doi":null,"is_oa":true,"landing_page_url":"https://scholarlypublications.universiteitleiden.nl/handle/1887/43590","pdf_url":"https://scholarlypublications.universiteitleiden.nl/download/1887/43590/1?col=81522199220002711","source":{"id":"https://openalex.org/S4306400850","display_name":"Leiden Repository (Leiden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I121797337","host_organization_name":"Leiden University","host_organization_lineage":["https://openalex.org/I121797337"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"http://purl.org/coar/resource_type/c_db06"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://scholarlypublications.universiteitleiden.nl/download/1887/43590/1?col=81522199220002711","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077451505","display_name":"Pedro Machado","orcid":"https://orcid.org/0000-0002-8411-7972","observed_orcids":["https://orcid.org/0000-0002-8411-7972","https://orcid.org/0009-0006-9634-9996"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Pedro Machado","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8411-7972","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5077451505"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11092","display_name":"Spondyloarthritis Studies and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11092","display_name":"Spondyloarthritis Studies and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13328","display_name":"Osteomyelitis and Bone Disorders Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11571","display_name":"Sarcoidosis and Beryllium Toxicity Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/axial-spondyloarthritis","display_name":"axial spondyloarthritis","score":1.0},{"id":"https://openalex.org/keywords/health-related-quality-of-life","display_name":"health-related quality of life","score":0.7559999823570251},{"id":"https://openalex.org/keywords/physical-functioning","display_name":"physical function","score":0.9660000205039978},{"id":"https://openalex.org/keywords/spinal-mobility","display_name":"spinal mobility","score":0.8019999861717224},{"id":"https://openalex.org/keywords/structural-damage","display_name":"structural damage","score":0.921999990940094},{"id":"https://openalex.org/keywords/new-bone-formation","display_name":"new bone formation","score":0.9649999737739563},{"id":"https://openalex.org/keywords/disease-activity-assessment","display_name":"disease activity assessment","score":0.6470000147819519},{"id":"https://openalex.org/keywords/asdas","display_name":"ASDAS","score":0.9359999895095825},{"id":"https://openalex.org/keywords/hla-b27","display_name":"HLA-B27","score":0.9810000061988831},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.9990000128746033},{"id":"https://openalex.org/keywords/psoriasis","display_name":"psoriasis","score":0.9959999918937683},{"id":"https://openalex.org/keywords/phenotypic-variation","display_name":"phenotypic variability","score":0.871999979019165},{"id":"https://openalex.org/keywords/structural-progression","display_name":"structural progression","score":0.8259999752044678}],"concepts":[{"id":"https://openalex.org/C2777402515","wikidata":"https://www.wikidata.org/wiki/Q52849","display_name":"Ankylosing spondylitis","level":2,"score":0.8102878332138062},{"id":"https://openalex.org/C2776213234","wikidata":"https://www.wikidata.org/wiki/Q28867094","display_name":"Axial spondyloarthritis","level":4,"score":0.7257663011550903},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.6867788434028625},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6151282787322998},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6144906878471375},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.43792349100112915},{"id":"https://openalex.org/C2779650986","wikidata":"https://www.wikidata.org/wiki/Q2165411","display_name":"Spondylitis","level":3,"score":0.4348735213279724},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.39772069454193115},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.34677955508232117},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.32010209560394287},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3132246732711792},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.2963630259037018},{"id":"https://openalex.org/C2778579456","wikidata":"https://www.wikidata.org/wiki/Q2213687","display_name":"Sacroiliitis","level":3,"score":0.1822308897972107}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:alma.31UKB_LEU:9940741356902711","doi":null,"is_oa":true,"landing_page_url":"https://scholarlypublications.universiteitleiden.nl/handle/1887/43590","pdf_url":"https://scholarlypublications.universiteitleiden.nl/download/1887/43590/1?col=81522199220002711","source":{"id":"https://openalex.org/S4306400850","display_name":"Leiden Repository (Leiden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I121797337","host_organization_name":"Leiden University","host_organization_lineage":["https://openalex.org/I121797337"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"http://purl.org/coar/resource_type/c_db06"},{"id":"pmh:oai:scholarlypublications.universiteitleiden.nl:item_2855379","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1887/43590","pdf_url":"https://hdl.handle.net/1887/43590","source":{"id":"https://openalex.org/S4306400850","display_name":"Leiden Repository (Leiden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I121797337","host_organization_name":"Leiden University","host_organization_lineage":["https://openalex.org/I121797337"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:openaccess.leidenuniv.nl:1887/43590","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1887/43590","pdf_url":null,"source":{"id":"https://openalex.org/S4306400850","display_name":"Leiden Repository (Leiden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I121797337","host_organization_name":"Leiden University","host_organization_lineage":["https://openalex.org/I121797337"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"urn:isbn:9789462333833","raw_type":"Doctoral Thesis"},{"id":"pmh:ul:oai:scholarlypublications.universiteitleiden.nl:item_2855379","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1887/43590","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"TITLE=None","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"mag:2587701055","doi":null,"is_oa":false,"landing_page_url":"https://openaccess.leidenuniv.nl/bitstream/1887/43590/1/22133_COV_FC_PT2_01_V2.p1.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:alma.31UKB_LEU:9940741356902711","doi":null,"is_oa":true,"landing_page_url":"https://scholarlypublications.universiteitleiden.nl/handle/1887/43590","pdf_url":"https://scholarlypublications.universiteitleiden.nl/download/1887/43590/1?col=81522199220002711","source":{"id":"https://openalex.org/S4306400850","display_name":"Leiden Repository (Leiden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I121797337","host_organization_name":"Leiden University","host_organization_lineage":["https://openalex.org/I121797337"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"http://purl.org/coar/resource_type/c_db06"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2587701055.pdf","grobid_xml":"https://content.openalex.org/works/W2587701055.grobid-xml"},"referenced_works_count":80,"referenced_works":["https://openalex.org/W15228753","https://openalex.org/W35214484","https://openalex.org/W96987653","https://openalex.org/W190211033","https://openalex.org/W1490432134","https://openalex.org/W1578313227","https://openalex.org/W1621490964","https://openalex.org/W1779994091","https://openalex.org/W1796527537","https://openalex.org/W1892171732","https://openalex.org/W1903233379","https://openalex.org/W1990305566","https://openalex.org/W1990876964","https://openalex.org/W1998668824","https://openalex.org/W2012643422","https://openalex.org/W2015406536","https://openalex.org/W2019789379","https://openalex.org/W2020346773","https://openalex.org/W2022449140","https://openalex.org/W2023812288","https://openalex.org/W2024172588","https://openalex.org/W2028275018","https://openalex.org/W2034659929","https://openalex.org/W2038377490","https://openalex.org/W2040865134","https://openalex.org/W2043234344","https://openalex.org/W2054215607","https://openalex.org/W2054703724","https://openalex.org/W2054909375","https://openalex.org/W2058882501","https://openalex.org/W2065075164","https://openalex.org/W2071921759","https://openalex.org/W2071933897","https://openalex.org/W2081388746","https://openalex.org/W2086070229","https://openalex.org/W2092734189","https://openalex.org/W2093370279","https://openalex.org/W2095816100","https://openalex.org/W2096703320","https://openalex.org/W2100284451","https://openalex.org/W2108275796","https://openalex.org/W2109172918","https://openalex.org/W2109946007","https://openalex.org/W2112776776","https://openalex.org/W2121308402","https://openalex.org/W2123235923","https://openalex.org/W2124242842","https://openalex.org/W2124597327","https://openalex.org/W2127609546","https://openalex.org/W2128425684","https://openalex.org/W2131403115","https://openalex.org/W2132842872","https://openalex.org/W2133816416","https://openalex.org/W2136584279","https://openalex.org/W2137662326","https://openalex.org/W2138557676","https://openalex.org/W2139351039","https://openalex.org/W2139851401","https://openalex.org/W2139924244","https://openalex.org/W2142527891","https://openalex.org/W2144632714","https://openalex.org/W2145881672","https://openalex.org/W2150646785","https://openalex.org/W2152059260","https://openalex.org/W2160623168","https://openalex.org/W2162890156","https://openalex.org/W2163741803","https://openalex.org/W2169307686","https://openalex.org/W2170809136","https://openalex.org/W2178132676","https://openalex.org/W2179418451","https://openalex.org/W2189787157","https://openalex.org/W2256495152","https://openalex.org/W2302869391","https://openalex.org/W2319669994","https://openalex.org/W2327593005","https://openalex.org/W2342957666","https://openalex.org/W2394995383","https://openalex.org/W2442385917","https://openalex.org/W2490910868"],"related_works":["https://openalex.org/W4408090263","https://openalex.org/W2921448685","https://openalex.org/W2106854296","https://openalex.org/W2193802385","https://openalex.org/W2793025543","https://openalex.org/W2790822947","https://openalex.org/W4398228954","https://openalex.org/W2551044684","https://openalex.org/W2909494126","https://openalex.org/W4392821726"],"abstract_inverted_index":{"This":[0],"thesis":[1],"focuses":[2],"on":[3],"the":[4,18,27,37,42,48,69,72,75,78,81,111,114,117,120,144,153,156,167,178],"assessment":[5,43],"and":[6,10,17,29,39,62,65,105,143,151,165,171,186],"monitoring":[7],"of":[8,31,41,44,71,94,110,146],"health":[9,85,91],"imaging":[11,108],"outcomes":[12,86],"in":[13,77,87,116,126,162,190],"axial":[14,32,88,127,163,191],"spondyloarthritis":[15],"(SpA)":[16],"relationship":[19,179],"between":[20,84,169,180],"these":[21],"outcomes.":[22],"Four":[23],"major":[24],"contributions":[25],"to":[26],"understanding":[28],"management":[30],"SpA":[33,164],"were":[34],"made:":[35],"1)":[36],"improvement":[38],"facilitation":[40],"disease":[45,59,99],"activity":[46,60],"using":[47],"Ankylosing":[49],"Spondylitis":[50],"Disease":[51],"Activity":[52],"Score":[53],"(ASDAS),":[54],"for":[55],"which":[56],"we":[57],"defined":[58],"cut-offs":[61],"response":[63],"criteria":[64],"provided":[66],"guidance":[67],"about":[68,80,119],"calculation":[70],"score;":[73],"2)":[74],"increase":[76,115],"knowledge":[79,118],"mutual":[82],"relationships":[83],"SpA,":[89,128],"namely":[90,129],"related":[92],"quality":[93],"life,":[95],"physical":[96],"function,":[97],"clinical":[98],"activity,":[100],"spinal":[101],"mobility,":[102],"structural":[103,160,172],"damage":[104],"magnetic":[106],"resonance":[107],"(MRI)":[109],"spine;":[112],"3)":[113],"factors":[121],"that":[122,158],"influence":[123],"phenotypic":[124],"variability":[125],"Human":[130],"Leukocyte":[131],"Antigen":[132],"B27":[133],"(HLA-B27)":[134],"positivity":[135],"(a":[136],"genetic":[137],"factor),":[138],"smoking":[139],"(an":[140,148],"environmental":[141],"factor)":[142],"presence":[145],"psoriasis":[147],"extra-articular":[149],"manifestation);":[150],"4)":[152],"insight":[154],"into":[155,166],"processes":[157],"drive":[159],"progression":[161],"link":[168],"inflammation":[170],"damage,":[173],"by":[174],"specifically":[175],"looking":[176],"at":[177],"MRI":[181,183],"inflammation,":[182],"fat":[184],"deposition":[185],"new":[187],"bone":[188],"formation":[189],"SpA.":[192]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-02-17T00:00:00"}