{"id":"https://openalex.org/W2587337080","doi":"https://doi.org/10.1016/j.jaci.2016.12.589","title":"Critical Role of IL-1beta and IL-17A in Transmission of Asthma Predisposition Across Generations","display_name":"Critical Role of IL-1beta and IL-17A in Transmission of Asthma Predisposition Across Generations","publication_year":2017,"publication_date":"2017-02-01","ids":{"openalex":"https://openalex.org/W2587337080","doi":"https://doi.org/10.1016/j.jaci.2016.12.589","mag":"2587337080"},"language":"en","primary_location":{"id":"doi:10.1016/j.jaci.2016.12.589","doi":"https://doi.org/10.1016/j.jaci.2016.12.589","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaci.2016.12.589","pdf_url":"http://www.jacionline.org/article/S0091674916321078/pdf","source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.jacionline.org/article/S0091674916321078/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101404198","display_name":"Magdalena M. Gorska","orcid":"https://orcid.org/0000-0001-7364-8703","observed_orcids":["https://orcid.org/0000-0001-7364-8703"]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Magdalena M. Gorska","raw_affiliation_strings":["National Jewish Health, Denver, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Jewish Health, Denver, CO","institution_ids":["https://openalex.org/I3019586173"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088059398","display_name":"Jerica L. Lenberg","orcid":"https://orcid.org/0000-0002-8907-7658","observed_orcids":["https://orcid.org/0000-0002-8907-7658"]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jerica Lenberg","raw_affiliation_strings":["National Jewish Health, Denver, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Jewish Health, Denver, CO","institution_ids":["https://openalex.org/I3019586173"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112752881","display_name":"Rafeul Alam","orcid":"https://orcid.org/0000-0001-8562-4207","observed_orcids":["https://orcid.org/0000-0001-8562-4207"]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rafeul Alam","raw_affiliation_strings":["National Jewish Health, Denver, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Jewish Health, Denver, CO","institution_ids":["https://openalex.org/I3019586173"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100728462","display_name":"Qian Qian","orcid":"https://orcid.org/0000-0001-6180-1731","observed_orcids":["https://orcid.org/0000-0001-6180-1731"]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qian Qian","raw_affiliation_strings":["National Jewish Health, Denver, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Jewish Health, Denver, CO","institution_ids":["https://openalex.org/I3019586173"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I3019586173"],"apc_list":{"value":4900,"currency":"USD","value_usd":4900},"apc_paid":null,"fwci":0.203,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.54922579,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"139","issue":"2","first_page":"AB180","last_page":"AB180"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":0.031099999323487282,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12528","display_name":"IL-33, ST2, and ILC Pathways","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.8379999995231628},{"id":"https://openalex.org/keywords/il-17a","display_name":"IL-17A","score":1.0},{"id":"https://openalex.org/keywords/intergenerational-transmission","display_name":"intergenerational transmission","score":0.8360000252723694},{"id":"https://openalex.org/keywords/diesel-exhaust-particles","display_name":"diesel exhaust particles","score":0.8560000061988831},{"id":"https://openalex.org/keywords/prenatal-exposure","display_name":"prenatal exposure","score":0.8009999990463257},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.9369999766349792},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.6259999871253967}],"concepts":[{"id":"https://openalex.org/C112672928","wikidata":"https://www.wikidata.org/wiki/Q239526","display_name":"Offspring","level":3,"score":0.7555978894233704},{"id":"https://openalex.org/C2776946954","wikidata":"https://www.wikidata.org/wiki/Q420291","display_name":"Ovalbumin","level":3,"score":0.7223941087722778},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6102484464645386},{"id":"https://openalex.org/C47348012","wikidata":"https://www.wikidata.org/wiki/Q99486570","display_name":"Interleukin 17","level":3,"score":0.530888020992279},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.4927211105823517},{"id":"https://openalex.org/C2777037409","wikidata":"https://www.wikidata.org/wiki/Q107238","display_name":"Eosinophil","level":3,"score":0.46344709396362305},{"id":"https://openalex.org/C74172505","wikidata":"https://www.wikidata.org/wiki/Q194908","display_name":"Interleukin","level":3,"score":0.4566534757614136},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.4456920921802521},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.43869197368621826},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.39077073335647583},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.293890118598938},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2914186716079712},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jaci.2016.12.589","doi":"https://doi.org/10.1016/j.jaci.2016.12.589","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaci.2016.12.589","pdf_url":"http://www.jacionline.org/article/S0091674916321078/pdf","source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.jaci.2016.12.589","doi":"https://doi.org/10.1016/j.jaci.2016.12.589","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaci.2016.12.589","pdf_url":"http://www.jacionline.org/article/S0091674916321078/pdf","source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2587337080.pdf","grobid_xml":"https://content.openalex.org/works/W2587337080.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2046271641","https://openalex.org/W2044740886","https://openalex.org/W2758343563","https://openalex.org/W2612319939","https://openalex.org/W3025372656","https://openalex.org/W2086993280","https://openalex.org/W2041674455","https://openalex.org/W2999615329","https://openalex.org/W2131422113","https://openalex.org/W4313349530"],"abstract_inverted_index":null,"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2017-02-17T00:00:00"}