{"id":"https://openalex.org/W258723702","doi":"https://doi.org/10.1023/a:1008882516700","title":"Simultaneous Prediction of Human Antithrombin III and Main Metabolites in Animal Cell Culture Processes by Near-Infrared Spectroscopy","display_name":"Simultaneous Prediction of Human Antithrombin III and Main Metabolites in Animal Cell Culture Processes by Near-Infrared Spectroscopy","publication_year":1998,"publication_date":"1998-05-01","ids":{"openalex":"https://openalex.org/W258723702","doi":"https://doi.org/10.1023/a:1008882516700","mag":"258723702"},"language":"en","primary_location":{"id":"doi:10.1023/a:1008882516700","doi":"https://doi.org/10.1023/a:1008882516700","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1008882516700","pdf_url":null,"source":{"id":"https://openalex.org/S129850652","display_name":"Biotechnology Techniques","issn_l":"0951-208X","issn":["0951-208X","1573-6784"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology Techniques","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062707618","display_name":"Sven Harthun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I31512782","display_name":"Technische Universit\u00e4t Darmstadt","ror":"https://ror.org/05n911h24","country_code":"DE","type":"education","lineage":["https://openalex.org/I31512782"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sven Harthun","raw_affiliation_strings":["Institut f\u00fcr Biochemie, Petersenstr., Technische Universit\u00e4t Darmstadt, D-64287, Darmstadt, Germany","Institut f\u00fcr Biochemie, Petersenstr., Technische Universit\u00e4t Darmstadt, Darmstadt, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Biochemie, Petersenstr., Technische Universit\u00e4t Darmstadt, D-64287, Darmstadt, Germany","institution_ids":["https://openalex.org/I31512782"]},{"raw_affiliation_string":"Institut f\u00fcr Biochemie, Petersenstr., Technische Universit\u00e4t Darmstadt, Darmstadt, Germany","institution_ids":["https://openalex.org/I31512782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013053030","display_name":"Kathrin Matischak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I31512782","display_name":"Technische Universit\u00e4t Darmstadt","ror":"https://ror.org/05n911h24","country_code":"DE","type":"education","lineage":["https://openalex.org/I31512782"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Kathrin Matischak","raw_affiliation_strings":["Institut f\u00fcr Biochemie, Petersenstr., Technische Universit\u00e4t Darmstadt, D-64287, Darmstadt, Germany","Institut f\u00fcr Biochemie, Petersenstr., Technische Universit\u00e4t Darmstadt, Darmstadt, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Biochemie, Petersenstr., Technische Universit\u00e4t Darmstadt, D-64287, Darmstadt, Germany","institution_ids":["https://openalex.org/I31512782"]},{"raw_affiliation_string":"Institut f\u00fcr Biochemie, Petersenstr., Technische Universit\u00e4t Darmstadt, Darmstadt, Germany","institution_ids":["https://openalex.org/I31512782"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026527299","display_name":"Peter Friedl","orcid":"https://orcid.org/0000-0002-0119-4041","observed_orcids":["https://orcid.org/0000-0002-0119-4041"]},"institutions":[{"id":"https://openalex.org/I31512782","display_name":"Technische Universit\u00e4t Darmstadt","ror":"https://ror.org/05n911h24","country_code":"DE","type":"education","lineage":["https://openalex.org/I31512782"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Peter Friedl","raw_affiliation_strings":["Institut f\u00fcr Biochemie, Petersenstr., Technische Universit\u00e4t Darmstadt, D-64287, Darmstadt, Germany","Institut f\u00fcr Biochemie, Petersenstr., Technische Universit\u00e4t Darmstadt, Darmstadt, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Biochemie, Petersenstr., Technische Universit\u00e4t Darmstadt, D-64287, Darmstadt, Germany","institution_ids":["https://openalex.org/I31512782"]},{"raw_affiliation_string":"Institut f\u00fcr Biochemie, Petersenstr., Technische Universit\u00e4t Darmstadt, Darmstadt, Germany","institution_ids":["https://openalex.org/I31512782"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5026527299"],"corresponding_institution_ids":["https://openalex.org/I31512782"],"apc_list":null,"apc_paid":null,"fwci":0.3056,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.45360616,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"12","issue":"5","first_page":"393","last_page":"398"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10640","display_name":"Spectroscopy and Chemometric Analyses","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10640","display_name":"Spectroscopy and Chemometric Analyses","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antithrombin-iii","display_name":"antithrombin III","score":0.9769999980926514},{"id":"https://openalex.org/keywords/near-infrared-spectroscopy","display_name":"near-infrared spectroscopy","score":0.8939999938011169},{"id":"https://openalex.org/keywords/cell-culture-supernatant","display_name":"cell culture supernatant","score":0.8220000267028809},{"id":"https://openalex.org/keywords/partial-least-squares-regression","display_name":"partial least squares regression","score":0.8579999804496765},{"id":"https://openalex.org/keywords/process-analytical-technology","display_name":"process analytical technology","score":0.5789999961853027},{"id":"https://openalex.org/keywords/bioprocess-automation","display_name":"bioprocess automation","score":0.6069999933242798}],"concepts":[{"id":"https://openalex.org/C22354355","wikidata":"https://www.wikidata.org/wiki/Q422009","display_name":"Partial least squares regression","level":2,"score":0.8779000043869019},{"id":"https://openalex.org/C165838908","wikidata":"https://www.wikidata.org/wiki/Q736777","display_name":"Calibration","level":2,"score":0.6276443600654602},{"id":"https://openalex.org/C161584116","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate statistics","level":2,"score":0.5539966225624084},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.4712572395801544},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.46399566531181335},{"id":"https://openalex.org/C151304367","wikidata":"https://www.wikidata.org/wiki/Q910067","display_name":"Chemometrics","level":2,"score":0.44625434279441833},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.43752846121788025},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39166995882987976},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2896585166454315},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.2796381115913391},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21563675999641418}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1023/a:1008882516700","doi":"https://doi.org/10.1023/a:1008882516700","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1008882516700","pdf_url":null,"source":{"id":"https://openalex.org/S129850652","display_name":"Biotechnology Techniques","issn_l":"0951-208X","issn":["0951-208X","1573-6784"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology Techniques","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1787164730","https://openalex.org/W1994824626","https://openalex.org/W1999851332","https://openalex.org/W2021873216","https://openalex.org/W2041076509","https://openalex.org/W2066207541","https://openalex.org/W2089962851","https://openalex.org/W2092582183","https://openalex.org/W2124691447","https://openalex.org/W2153332899"],"related_works":["https://openalex.org/W1045209952","https://openalex.org/W1979435167","https://openalex.org/W938898453","https://openalex.org/W1994824626","https://openalex.org/W1859076399","https://openalex.org/W4409100762","https://openalex.org/W2153726016","https://openalex.org/W2065151556","https://openalex.org/W2318569605","https://openalex.org/W2032961900"],"abstract_inverted_index":null,"counts_by_year":[{"year":2019,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-06-19T15:47:20.252518","created_date":"2016-06-24T00:00:00"}