{"id":"https://openalex.org/W2586941527","doi":"https://doi.org/10.1016/j.jaci.2016.12.855","title":"Environmental Adjuvants Induce Neuropilin-2 Expression in Human and Murine Alveolar Macrophages","display_name":"Environmental Adjuvants Induce Neuropilin-2 Expression in Human and Murine Alveolar Macrophages","publication_year":2017,"publication_date":"2017-02-01","ids":{"openalex":"https://openalex.org/W2586941527","doi":"https://doi.org/10.1016/j.jaci.2016.12.855","mag":"2586941527"},"language":"en","primary_location":{"id":"doi:10.1016/j.jaci.2016.12.855","doi":"https://doi.org/10.1016/j.jaci.2016.12.855","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaci.2016.12.855","pdf_url":"http://www.jacionline.org/article/S0091674916323739/pdf","source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.jacionline.org/article/S0091674916323739/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032891625","display_name":"Timothy P. Moran","orcid":"https://orcid.org/0000-0002-6832-9772","observed_orcids":["https://orcid.org/0000-0002-6832-9772"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy P. Moran","raw_affiliation_strings":["University of North Carolina School of Medicine, Chapel Hill, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of North Carolina School of Medicine, Chapel Hill, NC","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017871852","display_name":"Robert M. Immormino","orcid":"https://orcid.org/0000-0003-1998-1307","observed_orcids":["https://orcid.org/0000-0003-1998-1307"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert M. Immormino","raw_affiliation_strings":["Center for Environmental Medicine, Asthma and Lung Biology, Chapel Hill, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Environmental Medicine, Asthma and Lung Biology, Chapel Hill, NC","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081891061","display_name":"Hideki Nakano","orcid":"https://orcid.org/0000-0002-6343-4709","observed_orcids":["https://orcid.org/0000-0002-6343-4709"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hideki Nakano","raw_affiliation_strings":["National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016761421","display_name":"Neil E. Alexis","orcid":"https://orcid.org/0000-0002-9417-8269","observed_orcids":["https://orcid.org/0000-0002-9417-8269"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Neil Alexis","raw_affiliation_strings":["Center Environmental Med. Asthma/Lung Biology, Chapel Hill, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center Environmental Med. Asthma/Lung Biology, Chapel Hill, NC","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017261720","display_name":"Andrew J. Ghio","orcid":"https://orcid.org/0000-0003-0502-6448","observed_orcids":["https://orcid.org/0000-0003-0502-6448"]},"institutions":[{"id":"https://openalex.org/I1302368450","display_name":"Environmental Protection Agency","ror":"https://ror.org/03tns0030","country_code":"US","type":"government","lineage":["https://openalex.org/I1302368450"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew J. Ghio","raw_affiliation_strings":["US EPA, Chapel Hill, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"US EPA, Chapel Hill, NC","institution_ids":["https://openalex.org/I1302368450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010809550","display_name":"David B. Peden","orcid":"https://orcid.org/0000-0003-4526-4627","observed_orcids":["https://orcid.org/0000-0003-4526-4627","https://orcid.org/0000-0001-5668-2782"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David B. Peden","raw_affiliation_strings":["University of North Carolina at Chapel Hill School Medicine, Chapel Hill, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of North Carolina at Chapel Hill School Medicine, Chapel Hill, NC","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075455244","display_name":"Donald N. Cook","orcid":"https://orcid.org/0000-0002-0052-3755","observed_orcids":["https://orcid.org/0000-0002-0052-3755"]},"institutions":[{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donald N. Cook","raw_affiliation_strings":["National Institute of Environmental Health Sciences, Research Triangle Park, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Environmental Health Sciences, Research Triangle Park, NC","institution_ids":["https://openalex.org/I4210095140"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4900,"currency":"USD","value_usd":4900},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0242237,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"139","issue":"2","first_page":"AB265","last_page":"AB265"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.5327000021934509,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.5327000021934509,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.03880000114440918,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10870","display_name":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","score":0.025499999523162842,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuropilin-2","display_name":"neuropilin-2","score":0.8960000276565552},{"id":"https://openalex.org/keywords/neuropilin-1","display_name":"neuropilin-1","score":1.0},{"id":"https://openalex.org/keywords/alveolar-macrophages","display_name":"alveolar macrophages","score":0.9729999899864197},{"id":"https://openalex.org/keywords/lung-macrophages","display_name":"lung macrophages","score":0.722000002861023},{"id":"https://openalex.org/keywords/receptor-expression","display_name":"receptor expression","score":0.7720000147819519},{"id":"https://openalex.org/keywords/pulmonary-inflammation","display_name":"lung inflammation","score":0.3199999928474426}],"concepts":[{"id":"https://openalex.org/C26291073","wikidata":"https://www.wikidata.org/wiki/Q310484","display_name":"Ex vivo","level":3,"score":0.5090550780296326},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.44604671001434326},{"id":"https://openalex.org/C81729549","wikidata":"https://www.wikidata.org/wiki/Q4649475","display_name":"A549 cell","level":3,"score":0.44489753246307373},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.4447411596775055},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.4318036437034607},{"id":"https://openalex.org/C106420622","wikidata":"https://www.wikidata.org/wiki/Q1188971","display_name":"Neuropilin","level":5,"score":0.43018871545791626},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.42987996339797974},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.40361255407333374},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3515043258666992},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3464449942111969},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3030622601509094},{"id":"https://openalex.org/C34425596","wikidata":"https://www.wikidata.org/wiki/Q18033463","display_name":"Neuropilin 1","level":4,"score":0.29426470398902893},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.17164361476898193},{"id":"https://openalex.org/C2777025900","wikidata":"https://www.wikidata.org/wiki/Q29725","display_name":"Vascular endothelial growth factor","level":3,"score":0.10250446200370789},{"id":"https://openalex.org/C167734588","wikidata":"https://www.wikidata.org/wiki/Q4356503","display_name":"VEGF receptors","level":2,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jaci.2016.12.855","doi":"https://doi.org/10.1016/j.jaci.2016.12.855","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaci.2016.12.855","pdf_url":"http://www.jacionline.org/article/S0091674916323739/pdf","source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.jaci.2016.12.855","doi":"https://doi.org/10.1016/j.jaci.2016.12.855","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaci.2016.12.855","pdf_url":"http://www.jacionline.org/article/S0091674916323739/pdf","source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2586941527.pdf","grobid_xml":"https://content.openalex.org/works/W2586941527.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2274470595","https://openalex.org/W2799462396","https://openalex.org/W7071730795","https://openalex.org/W2782424698","https://openalex.org/W2937671780","https://openalex.org/W2350863884","https://openalex.org/W7131231080","https://openalex.org/W1922414080","https://openalex.org/W1993416504","https://openalex.org/W6910418181"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-02-17T00:00:00"}