{"id":"https://openalex.org/W2584005658","doi":null,"title":"Deciphering the Epigenetic Code in Embryonic and Dental Pulp Stem Cells.","display_name":"Deciphering the Epigenetic Code in Embryonic and Dental Pulp Stem Cells.","publication_year":2016,"publication_date":"2016-12-01","ids":{"openalex":"https://openalex.org/W2584005658","mag":"2584005658","pmid":"https://pubmed.ncbi.nlm.nih.gov/28018144","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5168831"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:4113753","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5168831","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5168831","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069642878","display_name":"Dashzeveg Bayarsaihan","orcid":"https://orcid.org/0000-0001-9080-1271","observed_orcids":["https://orcid.org/0000-0001-9080-1271"]},"institutions":[{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Dashzeveg Bayarsaihan","raw_affiliation_strings":["Institute for System Genomics and Center for Regenerative Medicine and Skeletal Development, University of Connecticut Health Center, Farmington, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for System Genomics and Center for Regenerative Medicine and Skeletal Development, University of Connecticut Health Center, Farmington, CT, USA","institution_ids":["https://openalex.org/I75929689"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5069642878"],"corresponding_institution_ids":["https://openalex.org/I75929689"],"apc_list":null,"apc_paid":null,"fwci":0.7682,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.71232517,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"89","issue":"4","first_page":"539","last_page":"563"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.6523000001907349,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.6523000001907349,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.2087000012397766,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.04439999908208847,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epigenetic-regulation","display_name":"epigenetic regulation","score":0.8650000095367432},{"id":"https://openalex.org/keywords/dental-pulp-stem-cells","display_name":"dental pulp stem cells","score":0.9419999718666077},{"id":"https://openalex.org/keywords/embryonic-stem-cells","display_name":"embryonic stem cells","score":0.9929999709129333},{"id":"https://openalex.org/keywords/chromatin-state","display_name":"chromatin state","score":0.746999979019165},{"id":"https://openalex.org/keywords/epigenetic-modifications","display_name":"epigenetic modifications","score":0.9179999828338623},{"id":"https://openalex.org/keywords/stem-cell-self-renewal","display_name":"stem cell self-renewal","score":0.7490000128746033},{"id":"https://openalex.org/keywords/stem-cell-differentiation","display_name":"stem cell differentiation","score":0.8180000185966492},{"id":"https://openalex.org/keywords/lineage-determination","display_name":"lineage determination","score":0.6340000033378601},{"id":"https://openalex.org/keywords/dental-pulp-regeneration","display_name":"dental pulp regeneration","score":0.6850000023841858},{"id":"https://openalex.org/keywords/tooth-regeneration","display_name":"tooth regeneration","score":0.6579999923706055},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.5230000019073486},{"id":"https://openalex.org/keywords/cell-matrix-interactions","display_name":"cell-matrix interactions","score":0.6060000061988831}],"concepts":[{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.8056538105010986},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.7573196887969971},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7051088809967041},{"id":"https://openalex.org/C117717151","wikidata":"https://www.wikidata.org/wiki/Q3589155","display_name":"Epigenome","level":5,"score":0.6753116250038147},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.6537324786186218},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.5336557030677795},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.514800488948822},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.5093970894813538},{"id":"https://openalex.org/C2777400515","wikidata":"https://www.wikidata.org/wiki/Q5259430","display_name":"Dental pulp stem cells","level":3,"score":0.47728481888771057},{"id":"https://openalex.org/C20875687","wikidata":"https://www.wikidata.org/wiki/Q2642600","display_name":"Adult stem cell","level":4,"score":0.45906785130500793},{"id":"https://openalex.org/C10854531","wikidata":"https://www.wikidata.org/wiki/Q1061415","display_name":"Regenerative medicine","level":3,"score":0.4534272849559784},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.4247780442237854},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3330537676811218},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.24835792183876038},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.18502336740493774},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.184037446975708}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003782","descriptor_name":"Dental Pulp","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D022661","descriptor_name":"RNA, Untranslated","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D022661","descriptor_name":"RNA, Untranslated","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D053595","descriptor_name":"Embryonic Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:4113753","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5168831","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5168831","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5168831","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yale J Biol Med","raw_type":"Text"},{"id":"pmid:28018144","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28018144","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Yale journal of biology and medicine","raw_type":"Journal Article"},{"id":"mag:2584005658","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28018144","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4113753","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5168831","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.46810001134872437}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":299,"referenced_works":["https://openalex.org/W71402579","https://openalex.org/W751678927","https://openalex.org/W1171241794","https://openalex.org/W1430106351","https://openalex.org/W1497808863","https://openalex.org/W1505844373","https://openalex.org/W1535940973","https://openalex.org/W1537233581","https://openalex.org/W1550293405","https://openalex.org/W1561427403","https://openalex.org/W1574982330","https://openalex.org/W1589145602","https://openalex.org/W1620383234","https://openalex.org/W1637058112","https://openalex.org/W1773401015","https://openalex.org/W1830479932","https://openalex.org/W1836985274","https://openalex.org/W1871697889","https://openalex.org/W1875059347","https://openalex.org/W1884290936","https://openalex.org/W1888271265","https://openalex.org/W1899099918","https://openalex.org/W1907909844","https://openalex.org/W1915195610","https://openalex.org/W1919870667","https://openalex.org/W1923882567","https://openalex.org/W1925000049","https://openalex.org/W1941138517","https://openalex.org/W1964121620","https://openalex.org/W1964420018","https://openalex.org/W1964813856","https://openalex.org/W1965813410","https://openalex.org/W1965979210","https://openalex.org/W1967211903","https://openalex.org/W1967269362","https://openalex.org/W1967708955","https://openalex.org/W1969231335","https://openalex.org/W1970578620","https://openalex.org/W1971578941","https://openalex.org/W1974069185","https://openalex.org/W1974330670","https://openalex.org/W1975093996","https://openalex.org/W1975470952","https://openalex.org/W1975872621","https://openalex.org/W1975945047","https://openalex.org/W1976682189","https://openalex.org/W1977463456","https://openalex.org/W1979437091","https://openalex.org/W1979603337","https://openalex.org/W1979981555","https://openalex.org/W1981030303","https://openalex.org/W1984173288","https://openalex.org/W1984827465","https://openalex.org/W1985370709","https://openalex.org/W1985690255","https://openalex.org/W1986543487","https://openalex.org/W1987371782","https://openalex.org/W1988244669","https://openalex.org/W1988963557","https://openalex.org/W1990354097","https://openalex.org/W1992355766","https://openalex.org/W1993813084","https://openalex.org/W1995046740","https://openalex.org/W1996554839","https://openalex.org/W1999401647","https://openalex.org/W2000180714","https://openalex.org/W2002086236","https://openalex.org/W2003902924","https://openalex.org/W2004763680","https://openalex.org/W2006618903","https://openalex.org/W2006643590","https://openalex.org/W2007660474","https://openalex.org/W2007662442","https://openalex.org/W2009166526","https://openalex.org/W2010007223","https://openalex.org/W2010980636","https://openalex.org/W2011334033","https://openalex.org/W2011753829","https://openalex.org/W2012400528","https://openalex.org/W2013127012","https://openalex.org/W2014609980","https://openalex.org/W2018492629","https://openalex.org/W2018658338","https://openalex.org/W2018865924","https://openalex.org/W2018968961","https://openalex.org/W2019631798","https://openalex.org/W2022658418","https://openalex.org/W2023520235","https://openalex.org/W2024629463","https://openalex.org/W2025092145","https://openalex.org/W2025553576","https://openalex.org/W2026061821","https://openalex.org/W2026872608","https://openalex.org/W2026914820","https://openalex.org/W2027646678","https://openalex.org/W2030416589","https://openalex.org/W2030427461","https://openalex.org/W2030513330","https://openalex.org/W2031251066","https://openalex.org/W2031764248","https://openalex.org/W2032352727","https://openalex.org/W2033927170","https://openalex.org/W2034709147","https://openalex.org/W2035049195","https://openalex.org/W2035638429","https://openalex.org/W2037363723","https://openalex.org/W2037914397","https://openalex.org/W2038143829","https://openalex.org/W2038320708","https://openalex.org/W2039594317","https://openalex.org/W2040412635","https://openalex.org/W2040795628","https://openalex.org/W2041125090","https://openalex.org/W2044655647","https://openalex.org/W2044810442","https://openalex.org/W2045509264","https://openalex.org/W2046345187","https://openalex.org/W2049627729","https://openalex.org/W2050628283","https://openalex.org/W2051911149","https://openalex.org/W2052130151","https://openalex.org/W2053213384","https://openalex.org/W2053408851","https://openalex.org/W2055718694","https://openalex.org/W2060463218","https://openalex.org/W2060500550","https://openalex.org/W2060944529","https://openalex.org/W2061667567","https://openalex.org/W2062777241","https://openalex.org/W2063687663","https://openalex.org/W2066818898","https://openalex.org/W2067842438","https://openalex.org/W2068469234","https://openalex.org/W2068742804","https://openalex.org/W2069433314","https://openalex.org/W2070471476","https://openalex.org/W2070925202","https://openalex.org/W2071006764","https://openalex.org/W2071108288","https://openalex.org/W2071412381","https://openalex.org/W2071979452","https://openalex.org/W2072466432","https://openalex.org/W2073948335","https://openalex.org/W2074244075","https://openalex.org/W2075052598","https://openalex.org/W2076154138","https://openalex.org/W2077908123","https://openalex.org/W2081121476","https://openalex.org/W2083069604","https://openalex.org/W2083553342","https://openalex.org/W2083837059","https://openalex.org/W2090978758","https://openalex.org/W2092027270","https://openalex.org/W2092865839","https://openalex.org/W2093800333","https://openalex.org/W2095111355","https://openalex.org/W2095237346","https://openalex.org/W2095626300","https://openalex.org/W2095884976","https://openalex.org/W2099069972","https://openalex.org/W2099343472","https://openalex.org/W2100156547","https://openalex.org/W2101912958","https://openalex.org/W2105918290","https://openalex.org/W2106399721","https://openalex.org/W2106880776","https://openalex.org/W2107287843","https://openalex.org/W2107866789","https://openalex.org/W2108983068","https://openalex.org/W2111198429","https://openalex.org/W2111309204","https://openalex.org/W2111964212","https://openalex.org/W2114323282","https://openalex.org/W2120257529","https://openalex.org/W2121825097","https://openalex.org/W2121910267","https://openalex.org/W2123731635","https://openalex.org/W2123773614","https://openalex.org/W2125314144","https://openalex.org/W2127455821","https://openalex.org/W2128151873","https://openalex.org/W2128235491","https://openalex.org/W2132081693","https://openalex.org/W2132316576","https://openalex.org/W2134374915","https://openalex.org/W2136079563","https://openalex.org/W2136121675","https://openalex.org/W2137271498","https://openalex.org/W2138110950","https://openalex.org/W2138690472","https://openalex.org/W2141008336","https://openalex.org/W2143091513","https://openalex.org/W2143277424","https://openalex.org/W2144406855","https://openalex.org/W2146056177","https://openalex.org/W2147690311","https://openalex.org/W2148862424","https://openalex.org/W2150090219","https://openalex.org/W2150406644","https://openalex.org/W2151743649","https://openalex.org/W2152478160","https://openalex.org/W2152713573","https://openalex.org/W2152791321","https://openalex.org/W2152831388","https://openalex.org/W2153093716","https://openalex.org/W2153343747","https://openalex.org/W2153529142","https://openalex.org/W2153991114","https://openalex.org/W2154746182","https://openalex.org/W2156163245","https://openalex.org/W2156467055","https://openalex.org/W2156983107","https://openalex.org/W2158375721","https://openalex.org/W2158594250","https://openalex.org/W2158693541","https://openalex.org/W2158934466","https://openalex.org/W2159016178","https://openalex.org/W2159804042","https://openalex.org/W2161955467","https://openalex.org/W2167776710","https://openalex.org/W2170748964","https://openalex.org/W2171117723","https://openalex.org/W2175884649","https://openalex.org/W2177690692","https://openalex.org/W2178139627","https://openalex.org/W2180790011","https://openalex.org/W2187077810","https://openalex.org/W2196409802","https://openalex.org/W2198059726","https://openalex.org/W2203521782","https://openalex.org/W2204436556","https://openalex.org/W2213096776","https://openalex.org/W2219655163","https://openalex.org/W2224318971","https://openalex.org/W2228561711","https://openalex.org/W2228951539","https://openalex.org/W2234424116","https://openalex.org/W2253944261","https://openalex.org/W2255354927","https://openalex.org/W2259747327","https://openalex.org/W2264818681","https://openalex.org/W2265113466","https://openalex.org/W2267070684","https://openalex.org/W2270112065","https://openalex.org/W2272013100","https://openalex.org/W2281185882","https://openalex.org/W2283488635","https://openalex.org/W2286944220","https://openalex.org/W2287999176","https://openalex.org/W2288092586","https://openalex.org/W2290125147","https://openalex.org/W2293880235","https://openalex.org/W2295032943","https://openalex.org/W2295297857","https://openalex.org/W2297193872","https://openalex.org/W2298534412","https://openalex.org/W2298901024","https://openalex.org/W2303848959","https://openalex.org/W2305930346","https://openalex.org/W2307735033","https://openalex.org/W2309421679","https://openalex.org/W2312929775","https://openalex.org/W2323455217","https://openalex.org/W2325267338","https://openalex.org/W2326956261","https://openalex.org/W2332027634","https://openalex.org/W2337673903","https://openalex.org/W2339858520","https://openalex.org/W2341512691","https://openalex.org/W2342153705","https://openalex.org/W2342917578","https://openalex.org/W2344298934","https://openalex.org/W2344758159","https://openalex.org/W2345911841","https://openalex.org/W2346016617","https://openalex.org/W2346509327","https://openalex.org/W2370331043","https://openalex.org/W2376409125","https://openalex.org/W2395672085","https://openalex.org/W2400513936","https://openalex.org/W2402793322","https://openalex.org/W2406103812","https://openalex.org/W2409356434","https://openalex.org/W2410577613","https://openalex.org/W2412491965","https://openalex.org/W2412580860","https://openalex.org/W2412898159","https://openalex.org/W2413827787","https://openalex.org/W2415515169","https://openalex.org/W2418308514","https://openalex.org/W2419237034","https://openalex.org/W2428381774","https://openalex.org/W2435325303","https://openalex.org/W2441337908","https://openalex.org/W2463417921","https://openalex.org/W2487895297","https://openalex.org/W2512340246","https://openalex.org/W2994286290","https://openalex.org/W4300464738"],"related_works":["https://openalex.org/W4313514826","https://openalex.org/W3093862003","https://openalex.org/W3215082211","https://openalex.org/W4220743188","https://openalex.org/W4399089660","https://openalex.org/W2774242727","https://openalex.org/W4281739611","https://openalex.org/W2291088710","https://openalex.org/W4206210781","https://openalex.org/W4404435718"],"abstract_inverted_index":{"A":[0,28],"close":[1],"cooperation":[2],"between":[3],"chromatin":[4],"states,":[5],"transcriptional":[6],"modulation,":[7],"and":[8,20,24,61,114,160],"epigenetic":[9,77,145],"modifications":[10],"is":[11,119],"required":[12],"for":[13,43,83,107],"establishing":[14],"appropriate":[15],"regulatory":[16],"circuits":[17],"underlying":[18],"self-renewal":[19],"differentiation":[21,154],"of":[22,31,75,99,142,156,164],"adult":[23],"embryonic":[25,157],"stem":[26,89,97,158],"cells.":[27],"growing":[29],"body":[30],"research":[32],"has":[33,79],"established":[34],"that":[35,122,147],"the":[36,47,68,72,76,100,112,133,139,152,161],"epigenome":[37],"topology":[38],"provides":[39],"a":[40,129],"structural":[41],"framework":[42],"engaging":[44],"genes":[45],"in":[46,88,93,111],"non-random":[48],"chromosomal":[49],"interactions":[50],"to":[51,150],"orchestrate":[52],"complex":[53],"processes":[54],"such":[55],"as":[56],"cell-matrix":[57],"interactions,":[58],"cell":[59,62],"adhesion":[60],"migration":[63],"during":[64],"lineage":[65,162],"commitment.":[66],"Over":[67],"past":[69],"few":[70],"years,":[71],"functional":[73],"dissection":[74],"landscape":[78],"become":[80],"increasingly":[81],"important":[82],"understanding":[84],"gene":[85],"expression":[86],"dynamics":[87],"cells":[90,98,159],"naturally":[91],"found":[92],"most":[94],"tissues.":[95],"Adult":[96],"human":[101],"dental":[102,166],"pulp":[103,125,167],"hold":[104],"great":[105],"promise":[106],"tissue":[108],"engineering,":[109],"particularly":[110],"skeletal":[113],"tooth":[115],"regenerative":[116],"medicine.":[117],"It":[118],"therefore":[120],"likely":[121],"progress":[123],"towards":[124],"regeneration":[126],"will":[127],"have":[128,148],"substantial":[130],"impact":[131],"on":[132],"clinical":[134],"research.":[135],"This":[136],"review":[137],"summarizes":[138],"current":[140],"state":[141],"knowledge":[143],"regarding":[144],"cues":[146],"evolved":[149],"regulate":[151],"pluripotent":[153],"potential":[155],"determination":[163],"developing":[165],"progenitors.":[168]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-02-10T00:00:00"}