{"id":"https://openalex.org/W2582463968","doi":"https://doi.org/10.1002/acr.23201","title":"Clinical and Serologic Features in Patients With Incomplete Lupus Classification Versus Systemic Lupus Erythematosus Patients and Controls","display_name":"Clinical and Serologic Features in Patients With Incomplete Lupus Classification Versus Systemic Lupus Erythematosus Patients and Controls","publication_year":2017,"publication_date":"2017-01-24","ids":{"openalex":"https://openalex.org/W2582463968","doi":"https://doi.org/10.1002/acr.23201","mag":"2582463968","pmid":"https://pubmed.ncbi.nlm.nih.gov/28118528","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5524597"},"language":"en","primary_location":{"id":"doi:10.1002/acr.23201","doi":"https://doi.org/10.1002/acr.23201","is_oa":false,"landing_page_url":"https://doi.org/10.1002/acr.23201","pdf_url":null,"source":{"id":"https://openalex.org/S13698240","display_name":"Arthritis Care & Research","issn_l":"0893-7524","issn":["0893-7524","1529-0123","2151-464X","2151-4658"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis Care &amp; Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC5524597","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065167560","display_name":"Teresa Aberle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Teresa Aberle","raw_affiliation_strings":["Oklahoma Medical Research Foundation Oklahoma City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oklahoma Medical Research Foundation Oklahoma City","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089058081","display_name":"Rebecka L. Bourn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rebecka L. Bourn","raw_affiliation_strings":["Oklahoma Medical Research Foundation Oklahoma City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oklahoma Medical Research Foundation Oklahoma City","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065514371","display_name":"Melissa E. Munroe","orcid":"https://orcid.org/0000-0002-6933-9745","observed_orcids":["https://orcid.org/0000-0002-6933-9745"]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melissa E. Munroe","raw_affiliation_strings":["Oklahoma Medical Research Foundation Oklahoma City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oklahoma Medical Research Foundation Oklahoma City","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100380208","display_name":"Hua Chen","orcid":"https://orcid.org/0000-0002-0641-2837","observed_orcids":["https://orcid.org/0000-0002-0641-2837"]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hua Chen","raw_affiliation_strings":["Oklahoma Medical Research Foundation Oklahoma City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oklahoma Medical Research Foundation Oklahoma City","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103740687","display_name":"Virginia Roberts","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Virginia C. Roberts","raw_affiliation_strings":["Oklahoma Medical Research Foundation Oklahoma City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oklahoma Medical Research Foundation Oklahoma City","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032779152","display_name":"Joel M. Guthridge","orcid":"https://orcid.org/0000-0002-9308-237X","observed_orcids":["https://orcid.org/0000-0002-9308-237X"]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joel M. Guthridge","raw_affiliation_strings":["Oklahoma Medical Research Foundation Oklahoma City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oklahoma Medical Research Foundation Oklahoma City","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055486497","display_name":"Krista M. Bean","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Krista Bean","raw_affiliation_strings":["Oklahoma Medical Research Foundation Oklahoma City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oklahoma Medical Research Foundation Oklahoma City","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103757944","display_name":"Julie M. Robertson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julie M. Robertson","raw_affiliation_strings":["Oklahoma Medical Research Foundation Oklahoma City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oklahoma Medical Research Foundation Oklahoma City","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036220201","display_name":"Kathy L. Moser Sivils","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kathy L. Sivils","raw_affiliation_strings":["Oklahoma Medical Research Foundation Oklahoma City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oklahoma Medical Research Foundation Oklahoma City","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052213129","display_name":"Astrid Rasmussen","orcid":"https://orcid.org/0000-0001-7744-2948","observed_orcids":["https://orcid.org/0000-0001-7744-2948"]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Astrid Rasmussen","raw_affiliation_strings":["Oklahoma Medical Research Foundation Oklahoma City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oklahoma Medical Research Foundation Oklahoma City","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068228927","display_name":"Meghan Liles","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Meghan Liles","raw_affiliation_strings":["Oklahoma Medical Research Foundation Oklahoma City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oklahoma Medical Research Foundation Oklahoma City","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052053321","display_name":"Joan T. Merrill","orcid":"https://orcid.org/0000-0002-4514-2382","observed_orcids":["https://orcid.org/0000-0002-4514-2382"]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joan T. Merrill","raw_affiliation_strings":["Oklahoma Medical Research Foundation Oklahoma City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oklahoma Medical Research Foundation Oklahoma City","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110152357","display_name":"John B. Harley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John B. Harley","raw_affiliation_strings":["Cincinnati Children's Hospital Medical Center and US Department of Veterans Affairs Medical Center Cincinnati Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cincinnati Children's Hospital Medical Center and US Department of Veterans Affairs Medical Center Cincinnati Ohio","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035534167","display_name":"Nancy J. Olsen","orcid":"https://orcid.org/0000-0002-6588-3364","observed_orcids":["https://orcid.org/0000-0002-6588-3364"]},"institutions":[{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy J. Olsen","raw_affiliation_strings":["Penn State Milton S. Hershey Medical Center Hershey Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Penn State Milton S. Hershey Medical Center Hershey Pennsylvania","institution_ids":["https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029731022","display_name":"David R. Karp","orcid":"https://orcid.org/0000-0002-9005-1690","observed_orcids":["https://orcid.org/0000-0002-9005-1690"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David R. Karp","raw_affiliation_strings":["University of Texas Southwestern Medical Center Dallas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas Southwestern Medical Center Dallas","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088206527","display_name":"Judith A. James","orcid":"https://orcid.org/0000-0002-9574-7355","observed_orcids":["https://orcid.org/0000-0002-9574-7355"]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]},{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Judith A. James","raw_affiliation_strings":["Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center Oklahoma City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center Oklahoma City","institution_ids":["https://openalex.org/I30558944","https://openalex.org/I49332381"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4640,"currency":"USD","value_usd":4640},"apc_paid":null,"fwci":4.9994,"has_fulltext":false,"cited_by_count":42,"citation_normalized_percentile":{"value":0.95581806,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"69","issue":"12","first_page":"1780","last_page":"1788"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":0.9919999837875366},{"id":"https://openalex.org/keywords/lupus-classification-criteria","display_name":"lupus classification criteria","score":0.796999990940094},{"id":"https://openalex.org/keywords/autoantibodies","display_name":"autoantibodies","score":0.8949999809265137},{"id":"https://openalex.org/keywords/antinuclear-antibodies","display_name":"antinuclear antibodies","score":0.9369999766349792},{"id":"https://openalex.org/keywords/b-lymphocyte-stimulator","display_name":"B lymphocyte stimulator","score":0.9150000214576721},{"id":"https://openalex.org/keywords/anticardiolipin-antibodies","display_name":"anticardiolipin antibodies","score":0.8769999742507935},{"id":"https://openalex.org/keywords/hydroxychloroquine","display_name":"hydroxychloroquine","score":0.7950000166893005},{"id":"https://openalex.org/keywords/race-and-ethnicity","display_name":"race and ethnicity","score":0.6269999742507935},{"id":"https://openalex.org/keywords/organ-involvement","display_name":"organ involvement","score":0.5899999737739563},{"id":"https://openalex.org/keywords/lupus-nephritis","display_name":"lupus nephritis","score":0.5509999990463257},{"id":"https://openalex.org/keywords/pericarditis","display_name":"pericarditis","score":0.8029999732971191},{"id":"https://openalex.org/keywords/immunomodulatory-therapy","display_name":"immunomodulatory therapy","score":0.75}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9119194746017456},{"id":"https://openalex.org/C2776912625","wikidata":"https://www.wikidata.org/wiki/Q1485","display_name":"Systemic lupus erythematosus","level":3,"score":0.658994197845459},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6519586443901062},{"id":"https://openalex.org/C2779123688","wikidata":"https://www.wikidata.org/wiki/Q421094","display_name":"Hydroxychloroquine","level":5,"score":0.6256715059280396},{"id":"https://openalex.org/C163764329","wikidata":"https://www.wikidata.org/wiki/Q785022","display_name":"Autoantibody","level":3,"score":0.6067025661468506},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.5910820960998535},{"id":"https://openalex.org/C149443304","wikidata":"https://www.wikidata.org/wiki/Q185390","display_name":"Anti-nuclear antibody","level":4,"score":0.5855830907821655},{"id":"https://openalex.org/C198451711","wikidata":"https://www.wikidata.org/wiki/Q327657","display_name":"Rheumatology","level":2,"score":0.5508109927177429},{"id":"https://openalex.org/C2776670291","wikidata":"https://www.wikidata.org/wiki/Q1779300","display_name":"Connective tissue disease","level":4,"score":0.5275142788887024},{"id":"https://openalex.org/C2775915377","wikidata":"https://www.wikidata.org/wiki/Q188297","display_name":"Lupus erythematosus","level":3,"score":0.43458691239356995},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.36805784702301025},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3283626437187195},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.27211034297943115},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2650355100631714},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.24147647619247437},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005006","descriptor_name":"Ethnicity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006886","descriptor_name":"Hydroxychloroquine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009626","descriptor_name":"Terminology as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011647","descriptor_name":"Puerto Rico","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012698","descriptor_name":"Serologic Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014767","descriptor_name":"United States Virgin Islands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017153","descriptor_name":"Antibodies, Anticardiolipin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D018501","descriptor_name":"Antirheumatic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D019084","descriptor_name":"Fluorescent Antibody Technique, Indirect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044469","descriptor_name":"Racial Groups","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053264","descriptor_name":"B-Cell Activating Factor","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D064966","descriptor_name":"British Virgin Islands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1002/acr.23201","doi":"https://doi.org/10.1002/acr.23201","is_oa":false,"landing_page_url":"https://doi.org/10.1002/acr.23201","pdf_url":null,"source":{"id":"https://openalex.org/S13698240","display_name":"Arthritis Care & Research","issn_l":"0893-7524","issn":["0893-7524","1529-0123","2151-464X","2151-4658"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis Care &amp; Research","raw_type":"journal-article"},{"id":"pmid:28118528","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28118528","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis care & research","raw_type":"Comparative Study"},{"id":"pmh:oai:europepmc.org:5227511","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5524597","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5524597","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5524597","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Arthritis Care Res (Hoboken)","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5227511","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5524597","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1208854630","display_name":"Science in a Culture of Mentoring","funder_award_id":"P30GM103510","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G1754944998","display_name":"Understanding early events in lupus autoimmunity to aid prevention","funder_award_id":"U01AI101934","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G2436766538","display_name":"Genetic Linkage in Lupus","funder_award_id":"R37AI024717","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G2495457850","display_name":"National Biological Sample and Data Repository for PAH","funder_award_id":"R24HL105333","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3286611938","display_name":"Mechanisms of genetic risk at 2p23 in Eosinophilic Esophagitis","funder_award_id":"R01DK107502","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G3637209626","display_name":"Better Outcomes for Children: Promoting Excellence in Healthcare Genomics to Inform Policy","funder_award_id":"U01HG008666","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G3946412392","display_name":null,"funder_award_id":"I01\u2010BX\u2010001834","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G4734522750","display_name":"Oklahoma Rheumatic Disease Research Cores Center","funder_award_id":"P30AR053483","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G639722539","display_name":"Oklahoma Autoimmunity Center of Excellence Mechanisms of Disease Flare","funder_award_id":"U19AI082714","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000866793","display_name":"Cincinnati Rheumatic Diseases Resource Center","funder_award_id":"P30AR070549","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G9000876880","display_name":"Genetic Linkage in Lupus","funder_award_id":"R01AI024717","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000883401","display_name":"Oklahoma Shared Clinical and Translational Resources","funder_award_id":"U54GM104938","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306127","display_name":"U.S. Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W1747729985","https://openalex.org/W1820454135","https://openalex.org/W1937760409","https://openalex.org/W1973611836","https://openalex.org/W1985181188","https://openalex.org/W2004135257","https://openalex.org/W2009705929","https://openalex.org/W2013635565","https://openalex.org/W2015040567","https://openalex.org/W2017481450","https://openalex.org/W2026386953","https://openalex.org/W2029002123","https://openalex.org/W2034534130","https://openalex.org/W2036731830","https://openalex.org/W2052251121","https://openalex.org/W2053434841","https://openalex.org/W2053527795","https://openalex.org/W2060844805","https://openalex.org/W2061025708","https://openalex.org/W2062637839","https://openalex.org/W2063072887","https://openalex.org/W2066257150","https://openalex.org/W2070448964","https://openalex.org/W2070527591","https://openalex.org/W2073781275","https://openalex.org/W2073887351","https://openalex.org/W2079704511","https://openalex.org/W2091675224","https://openalex.org/W2093322537","https://openalex.org/W2095732560","https://openalex.org/W2103114230","https://openalex.org/W2105880264","https://openalex.org/W2106921684","https://openalex.org/W2110267964","https://openalex.org/W2115368068","https://openalex.org/W2119478254","https://openalex.org/W2129153331","https://openalex.org/W2144382874","https://openalex.org/W2146203649","https://openalex.org/W2155028518","https://openalex.org/W2159860161","https://openalex.org/W2161884430","https://openalex.org/W2279875163","https://openalex.org/W2302024964","https://openalex.org/W2312074945","https://openalex.org/W2338263211","https://openalex.org/W2474315976","https://openalex.org/W2596603956"],"related_works":["https://openalex.org/W2070448964","https://openalex.org/W2520776640","https://openalex.org/W4313385484","https://openalex.org/W4416448832","https://openalex.org/W4385639594","https://openalex.org/W2063072887","https://openalex.org/W2561216715","https://openalex.org/W4212910864","https://openalex.org/W4297374850","https://openalex.org/W3038117397"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Incomplete":[1],"lupus":[2,16],"erythematosus":[3,17],"(ILE)":[4],"involves":[5],"clinical":[6,36],"and/or":[7],"serologic":[8],"manifestations":[9,214,259],"consistent":[10],"with":[11,224],"but":[12,236],"insufficient":[13],"for":[14,67],"systemic":[15],"(SLE)":[18],"classification.":[19],"Because":[20],"the":[21,35,59,99],"nature":[22],"of":[23,47,55,73,218],"ILE":[24,48,80,133,150,161,196,204,219,241,258,271],"is":[25],"poorly":[26],"understood":[27],"and":[28,40,49,63,70,88,106,124,148,176,221,275,279],"no":[29],"treatment":[30],"recommendations":[31],"exist,":[32],"we":[33],"examined":[34],"manifestations,":[37],"medication":[38,68],"history,":[39],"immunologic":[41],"features":[42],"in":[43,58,195,216,240],"a":[44],"diverse":[45],"collection":[46],"SLE":[50,89,138,168,243,277],"patients.":[51],"METHODS:":[52],"Medical":[53],"records":[54],"subjects":[56],"enrolled":[57],"Lupus":[60],"Family":[61],"Registry":[62],"Repository":[64],"were":[65,112,135,152,177,193,222],"reviewed":[66],"history":[69],"American":[71,154,226],"College":[72],"Rheumatology":[74],"(ACR)":[75],"classification":[76],"criteria":[77],"to":[78,180,268,280,285],"identify":[79],"patients":[81,90,134,139,151,162,169,197,220,244],"(3":[82],"ACR":[83,92],"criteria;":[84,93],"n":[85,94],"=":[86,95,202,208,229],"440)":[87],"(\u22654":[91],"3,397).":[96],"Participants":[97],"completed":[98],"Connective":[100],"Tissue":[101],"Disease":[102],"Screening":[103],"Questionnaire.":[104],"Anticardiolipin":[105],"plasma":[107],"B":[108],"lymphocyte":[109],"stimulator":[110],"(BLyS)":[111],"measured":[113],"by":[114,121,127,255],"enzyme-linked":[115],"immunosorbent":[116],"assay,":[117],"antinuclear":[118],"antibodies":[119],"(ANAs)":[120],"indirect":[122],"immunofluorescence,":[123],"13":[125],"autoantibodies":[126],"bead-based":[128],"assays.":[129],"RESULTS:":[130],"On":[131],"average,":[132],"older":[136],"than":[137,167,242],"(46.2":[140],"years":[141],"versus":[142,156,171,186,246],"42.0":[143],"years;":[144],"P":[145,158,173,188,201,207,248],"<":[146,159,174,189,199,205,249],"0.0001),":[147],"fewer":[149,164],"African":[153],"(23.9%":[155],"32.2%;":[157],"0.001).":[160],"exhibited":[163],"autoantibody":[165],"specificities":[166],"(1.3":[170],"2.6;":[172],"0.0001)":[175],"less":[178,238],"likely":[179],"have":[181],"ANA":[182],"titers":[183],"\u22651:1,080":[184],"(10.5%":[185],"19.5%;":[187],"0.0001).":[190,250],"BLyS":[191],"levels":[192],"intermediate":[194],"(controls":[198],"ILE;":[200],"0.016;":[203],"SLE;":[206],"0.008).":[209],"Pericarditis,":[210],"renal,":[211],"or":[212],"neurologic":[213],"occurred":[215],"12.5%":[217],"associated":[223],"non-European":[225],"race/ethnicity":[227],"(P":[228],"0.012).":[230],"Hydroxychloroquine":[231],"use":[232],"increased":[233],"over":[234],"time,":[235],"was":[237],"frequent":[239],"(65.2%":[245],"83.1%;":[247],"CONCLUSION:":[251],"Although":[252],"usually":[253],"characterized":[254],"milder":[256],"symptoms,":[257],"may":[260],"require":[261],"immunomodulatory":[262],"treatments.":[263],"Longitudinal":[264],"studies":[265],"are":[266],"necessary":[267],"understand":[269],"how":[270],"affects":[272],"organ":[273],"damage":[274],"future":[276],"risk,":[278],"delineate":[281],"molecular":[282],"pathways":[283],"unique":[284],"ILE.":[286]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":5}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2017-02-03T00:00:00"}