{"id":"https://openalex.org/W2579908076","doi":null,"title":"VISUALIZATION AND ANALYSIS OF MURAL THROMBOGENESIS (PLATELET ADHESION, COLLAGEN, POLYURETHANE, DIGITAL IMAGE PROCESSING)","display_name":"VISUALIZATION AND ANALYSIS OF MURAL THROMBOGENESIS (PLATELET ADHESION, COLLAGEN, POLYURETHANE, DIGITAL IMAGE PROCESSING)","publication_year":1986,"publication_date":"1986-01-01","ids":{"openalex":"https://openalex.org/W2579908076","mag":"2579908076"},"language":"en","primary_location":{"id":"pmh:oai:repository.rice.edu:1911/15983","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/1911/15983">https://hdl.handle.net/1911/15983</a>.","pdf_url":null,"source":{"id":"https://openalex.org/S4306401268","display_name":"Rice Research Repository (Rice University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I74775410","host_organization_name":"Rice University","host_organization_lineage":["https://openalex.org/I74775410"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031517705","display_name":"Jeffrey A. Hubbell","orcid":"https://orcid.org/0000-0003-0276-5456","observed_orcids":["https://orcid.org/0000-0003-0276-5456"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jeffrey A. Hubbell","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0276-5456","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5031517705"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.4708999991416931,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.4708999991416931,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.2506999969482422,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.24300000071525574,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/platelet-adhesion","display_name":"platelet adhesion","score":0.953000009059906},{"id":"https://openalex.org/keywords/collagen-coated-surfaces","display_name":"collagen-coated surfaces","score":0.6499999761581421},{"id":"https://openalex.org/keywords/polyurethane-surfaces","display_name":"polyurethane surfaces","score":0.9589999914169312},{"id":"https://openalex.org/keywords/wall-shear-rate","display_name":"wall shear rate","score":0.8619999885559082},{"id":"https://openalex.org/keywords/thrombus-growth","display_name":"thrombus growth","score":0.8299999833106995},{"id":"https://openalex.org/keywords/thrombus-embolization","display_name":"thrombus embolization","score":0.9539999961853027},{"id":"https://openalex.org/keywords/leukocyte-adhesion","display_name":"leukocyte adhesion","score":0.9610000252723694},{"id":"https://openalex.org/keywords/thrombin","display_name":"thrombin","score":0.8029999732971191},{"id":"https://openalex.org/keywords/thromboxane-a2","display_name":"thromboxane A2","score":0.9829999804496765},{"id":"https://openalex.org/keywords/adenosine-diphosphate","display_name":"adenosine diphosphate","score":0.9850000143051147},{"id":"https://openalex.org/keywords/heparin","display_name":"heparin","score":0.6980000138282776},{"id":"https://openalex.org/keywords/antithrombin-iii","display_name":"antithrombin III","score":0.996999979019165},{"id":"https://openalex.org/keywords/parallel-plate-flow-chamber","display_name":"parallel plate flow chamber","score":0.5839999914169312}],"concepts":[{"id":"https://openalex.org/C2777420470","wikidata":"https://www.wikidata.org/wiki/Q219423","display_name":"Mural","level":3,"score":0.8026652336120605},{"id":"https://openalex.org/C2909954168","wikidata":"https://www.wikidata.org/wiki/Q860755","display_name":"Digital image analysis","level":2,"score":0.661740779876709},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.6367579698562622},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.48100194334983826},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.4523395895957947},{"id":"https://openalex.org/C2779578285","wikidata":"https://www.wikidata.org/wiki/Q146322","display_name":"Polyurethane","level":2,"score":0.44811612367630005},{"id":"https://openalex.org/C2993272671","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet adhesion","level":3,"score":0.4436380863189697},{"id":"https://openalex.org/C9417928","wikidata":"https://www.wikidata.org/wiki/Q1070689","display_name":"Image processing","level":3,"score":0.43581241369247437},{"id":"https://openalex.org/C104317675","wikidata":"https://www.wikidata.org/wiki/Q1070689","display_name":"Digital image processing","level":4,"score":0.41182172298431396},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3683446943759918},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.34586480259895325},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.297637403011322},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2731934189796448},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.26171034574508667},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.24088254570960999},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.24057123064994812},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20730918645858765},{"id":"https://openalex.org/C153349607","wikidata":"https://www.wikidata.org/wiki/Q36649","display_name":"Visual arts","level":1,"score":0.13884469866752625},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.08792886137962341},{"id":"https://openalex.org/C205783811","wikidata":"https://www.wikidata.org/wiki/Q11629","display_name":"Painting","level":2,"score":0.08678534626960754}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:repository.rice.edu:1911/15983","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/1911/15983">https://hdl.handle.net/1911/15983</a>.","pdf_url":null,"source":{"id":"https://openalex.org/S4306401268","display_name":"Rice Research Repository (Rice University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I74775410","host_organization_name":"Rice University","host_organization_lineage":["https://openalex.org/I74775410"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"pmh:oai:scholarship.rice.edu:1911/15983","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1911/15983","pdf_url":null,"source":{"id":"https://openalex.org/S4306401268","display_name":"Rice Research Repository (Rice University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I74775410","host_organization_name":"Rice University","host_organization_lineage":["https://openalex.org/I74775410"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:2579908076","doi":null,"is_oa":false,"landing_page_url":"https://scholarship.rice.edu/handle/1911/15983","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Sustainable cities and communities","score":0.4399999976158142,"id":"https://metadata.un.org/sdg/11"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2075957553","https://openalex.org/W1970531209","https://openalex.org/W2731161460","https://openalex.org/W2431768466","https://openalex.org/W2061936528","https://openalex.org/W782687944","https://openalex.org/W2561824243","https://openalex.org/W2411130217","https://openalex.org/W2004266014","https://openalex.org/W2576815305"],"abstract_inverted_index":{"Epi-fluorescence":[0],"video":[1],"microscopy,":[2],"digital":[3],"image":[4],"processing,":[5],"and":[6,13,22,42,49,70,111,127,143,168,186,211,261,266],"photodiode":[7],"photometry":[8],"were":[9,52,120,161,235,269],"used":[10,37],"to":[11,149,178,200,218,250,272],"visualize":[12],"analyze":[14],"mural":[15],"thrombogenesis":[16],"on":[17,86,91,138],"collagen":[18,93],"coated":[19,94,141],"glass,":[20],"polyurethane,":[21],"nylon":[23,140,151],"surfaces":[24],"in":[25,170,191,206,241,256],"contact":[26,242],"with":[27,223,243],"flowing":[28,244],"whole":[29],"blood.":[30,245],"A":[31],"parallel":[32],"plate":[33],"flow":[34],"chamber":[35],"was":[36,153,198,216,247],"as":[38,81,280],"the":[39,65,77,87,92,102,115,139,150,171,180,184,192,207,257],"test":[40],"system,":[41],"wall":[43,124,132],"shear":[44,125,133],"rates":[45,126],"of":[46,64,67,76,79,84,173,183,188,194,202,209,220,231,252,259,274],"100,":[47],"500,":[48],"1500":[50],"sec('-1)":[51],"considered.":[53,107],"The":[54],"technique":[55],"permitted":[56],"real-time":[57],"visualization,":[58],"high":[59,71,131],"resolution,":[60,72],"quantitative,":[61,73],"off-line":[62],"measurement":[63,75],"growth":[66],"individual":[68],"thrombi":[69,97,136],"end-point":[74],"accumulation":[78],"platelets":[80],"a":[82,156,174,224,238],"function":[83],"position":[85],"surface.\\nThrombi":[88],"grew":[89,110,137],"rapidly":[90,109],"surface.":[95,117],"These":[96,118],"exhibited":[98],"little":[99],"embolization":[100],"over":[101],"two":[103],"minute":[104],"exposure":[105],"times":[106],"Thrombi":[108],"subsequently":[112,144],"embolized":[113],"from":[114],"polyurethane":[116],"emboli":[119],"large":[121,239],"for":[122,130,163,227],"low":[123],"very":[128],"small":[129],"rates.":[134],"Small":[135],"surface":[142,152,240],"embolized.":[145],"Significant":[146],"leukocyte":[147],"adhesion":[148],"seen":[154,199,217,249,271],"after":[155],"brief":[157],"stagnation":[158],"period.\\nConcentration":[159],"profiles":[160,230],"calculated":[162,236],"adenosine":[164,228,267],"diphosphate,":[165],"thromboxane":[166],"A(,2),":[167],"thrombin":[169],"neighborhood":[172],"single":[175],"growing":[176],"thrombus":[177,195],"evaluate":[179],"possible":[181],"role":[182,226],"generation":[185],"release":[187],"these":[189,232],"substances":[190],"mechanism":[193],"growth.":[196],"Thrombin":[197,246],"be":[201,219,251,273],"profound":[203,253,279],"importance,":[204,222,254,275],"even":[205,255],"presence":[208,258],"heparin":[210,260],"antithrombin":[212,262],"III.":[213,263],"Thromboxane":[214,264],"A(,2)":[215,265],"some":[221],"lesser":[225],"diphosphate.\\nConcentration":[229],"same":[233],"species":[234],"near":[237],"again":[248],"diphosphate":[268],"also":[270],"albeit":[276],"not":[277],"so":[278],"thrombin.":[281]},"counts_by_year":[],"updated_date":"2026-09-05T08:02:43.246662","created_date":"2017-02-03T00:00:00"}