{"id":"https://openalex.org/W2579100141","doi":"https://doi.org/10.1186/s12977-017-0329-6","title":"Evidence against a role for jaagsiekte sheep retrovirus in human lung cancer","display_name":"Evidence against a role for jaagsiekte sheep retrovirus in human lung cancer","publication_year":2017,"publication_date":"2017-01-20","ids":{"openalex":"https://openalex.org/W2579100141","doi":"https://doi.org/10.1186/s12977-017-0329-6","mag":"2579100141","pmid":"https://pubmed.ncbi.nlm.nih.gov/28107820","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5248497"},"language":"en","primary_location":{"id":"doi:10.1186/s12977-017-0329-6","doi":"https://doi.org/10.1186/s12977-017-0329-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12977-017-0329-6","pdf_url":"https://retrovirology.biomedcentral.com/track/pdf/10.1186/s12977-017-0329-6","source":{"id":"https://openalex.org/S54115554","display_name":"Retrovirology","issn_l":"1742-4690","issn":["1742-4690"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Retrovirology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://retrovirology.biomedcentral.com/track/pdf/10.1186/s12977-017-0329-6","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026763137","display_name":"A. Dusty Miller","orcid":"https://orcid.org/0000-0002-3736-3660","observed_orcids":["https://orcid.org/0000-0002-3736-3660"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"A. Dusty Miller","raw_affiliation_strings":[", 17915 Edmundson Rd, Sisters, OR, 97759, USA. dmiller@fredhutch.org","Department of Pathology, University of Washington, Seattle, WA, USA. dmiller@fredhutch.org","Fred Hutchinson Cancer Research Center, Seattle, WA, USA. dmiller@fredhutch.org","Department of Pathology, University of Washington, Seattle, USA","Fred Hutchinson Cancer Research Center, Seattle, USA","Sisters, USA"],"raw_orcid":"https://orcid.org/0000-0002-3736-3660","affiliations":[{"raw_affiliation_string":", 17915 Edmundson Rd, Sisters, OR, 97759, USA. dmiller@fredhutch.org","institution_ids":[]},{"raw_affiliation_string":"Department of Pathology, University of Washington, Seattle, WA, USA. dmiller@fredhutch.org","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Fred Hutchinson Cancer Research Center, Seattle, WA, USA. dmiller@fredhutch.org","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Department of Pathology, University of Washington, Seattle, USA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Fred Hutchinson Cancer Research Center, Seattle, USA","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Sisters, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069609423","display_name":"Marcelo De Las Heras","orcid":"https://orcid.org/0000-0003-3792-287X","observed_orcids":["https://orcid.org/0000-0003-3792-287X"]},"institutions":[{"id":"https://openalex.org/I255234318","display_name":"Universidad de Zaragoza","ror":"https://ror.org/012a91z28","country_code":"ES","type":"education","lineage":["https://openalex.org/I255234318"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Marcelo De las Heras","raw_affiliation_strings":["Department of Animal Pathology, Zaragoza University, Zaragoza, Spain"],"raw_orcid":"https://orcid.org/0000-0003-3792-287X","affiliations":[{"raw_affiliation_string":"Department of Animal Pathology, Zaragoza University, Zaragoza, Spain","institution_ids":["https://openalex.org/I255234318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015246989","display_name":"Jingyou Yu","orcid":"https://orcid.org/0000-0002-0775-6623","observed_orcids":["https://orcid.org/0000-0002-0775-6623"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]},{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jingyou Yu","raw_affiliation_strings":["Center for Retrovirus Research, Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA","Department of Molecular Microbiology and Immunology, Bond Life Sciences Canter, University of Missouri, Columbia, MO, USA","Center for Retrovirus Research, Department of Veterinary Biosciences, The Ohio State University, Columbus, USA","Department of Molecular Microbiology and Immunology, Bond Life Sciences Canter, University of Missouri, Columbia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Retrovirus Research, Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology, Bond Life Sciences Canter, University of Missouri, Columbia, MO, USA","institution_ids":["https://openalex.org/I76835614"]},{"raw_affiliation_string":"Center for Retrovirus Research, Department of Veterinary Biosciences, The Ohio State University, Columbus, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology, Bond Life Sciences Canter, University of Missouri, Columbia, USA","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087522794","display_name":"Fushun Zhang","orcid":"https://orcid.org/0000-0002-0696-8907","observed_orcids":["https://orcid.org/0000-0002-0696-8907"]},"institutions":[{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fushun Zhang","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology, Bond Life Sciences Canter, University of Missouri, Columbia, MO, USA","Department of Molecular Microbiology and Immunology, Bond Life Sciences Canter, University of Missouri, Columbia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology, Bond Life Sciences Canter, University of Missouri, Columbia, MO, USA","institution_ids":["https://openalex.org/I76835614"]},{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology, Bond Life Sciences Canter, University of Missouri, Columbia, USA","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062868933","display_name":"Shan\u2010Lu Liu","orcid":"https://orcid.org/0000-0003-1620-3817","observed_orcids":["https://orcid.org/0000-0003-1620-3817"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]},{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shan-Lu Liu","raw_affiliation_strings":["Center for Retrovirus Research, Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA","Department of Molecular Microbiology and Immunology, Bond Life Sciences Canter, University of Missouri, Columbia, MO, USA","Center for Retrovirus Research, Department of Veterinary Biosciences, The Ohio State University, Columbus, USA","Department of Molecular Microbiology and Immunology, Bond Life Sciences Canter, University of Missouri, Columbia, USA"],"raw_orcid":"https://orcid.org/0000-0003-1620-3817","affiliations":[{"raw_affiliation_string":"Center for Retrovirus Research, Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology, Bond Life Sciences Canter, University of Missouri, Columbia, MO, USA","institution_ids":["https://openalex.org/I76835614"]},{"raw_affiliation_string":"Center for Retrovirus Research, Department of Veterinary Biosciences, The Ohio State University, Columbus, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology, Bond Life Sciences Canter, University of Missouri, Columbia, USA","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016422217","display_name":"Andrew E. Vaughan","orcid":"https://orcid.org/0000-0001-5740-643X","observed_orcids":["https://orcid.org/0000-0001-5740-643X"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew E. Vaughan","raw_affiliation_strings":["Department of Medicine, University of California San Francisco, San Francisco, CA, USA","Fred Hutchinson Cancer Research Center, Seattle, WA, USA","Department of Medicine, University of California San Francisco, San Francisco, USA","Fred Hutchinson Cancer Research Center, Seattle, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of California San Francisco, San Francisco, CA, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Fred Hutchinson Cancer Research Center, Seattle, WA, USA","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Department of Medicine, University of California San Francisco, San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Fred Hutchinson Cancer Research Center, Seattle, USA","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011306393","display_name":"Thomas L. Vaughan","orcid":"https://orcid.org/0000-0003-1537-0242","observed_orcids":["https://orcid.org/0000-0003-1537-0242"]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas L. Vaughan","raw_affiliation_strings":["Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA","Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, USA"],"raw_orcid":"https://orcid.org/0000-0003-1537-0242","affiliations":[{"raw_affiliation_string":"Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, USA","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006847197","display_name":"Ra\u00fal Rosadio A.","orcid":"https://orcid.org/0000-0002-4480-8103","observed_orcids":["https://orcid.org/0000-0002-4480-8103"]},"institutions":[{"id":"https://openalex.org/I192513696","display_name":"National University of San Marcos","ror":"https://ror.org/006vs7897","country_code":"PE","type":"education","lineage":["https://openalex.org/I192513696"]}],"countries":["PE"],"is_corresponding":false,"raw_author_name":"Raul Rosadio","raw_affiliation_strings":["Veterinary Faculty, National University of San Marcos, Lima, Peru"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterinary Faculty, National University of San Marcos, Lima, Peru","institution_ids":["https://openalex.org/I192513696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059243928","display_name":"Stefano Rocca","orcid":"https://orcid.org/0009-0004-1490-5860","observed_orcids":["https://orcid.org/0009-0004-1490-5860"]},"institutions":[{"id":"https://openalex.org/I159650629","display_name":"University of Sassari","ror":"https://ror.org/01bnjbv91","country_code":"IT","type":"education","lineage":["https://openalex.org/I159650629"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Stefano Rocca","raw_affiliation_strings":["Department of Veterinary Medicine, Sassari University, Sassari, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Medicine, Sassari University, Sassari, Italy","institution_ids":["https://openalex.org/I159650629"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008816822","display_name":"Giuseppe Palmieri","orcid":"https://orcid.org/0000-0002-4350-2276","observed_orcids":["https://orcid.org/0000-0002-4350-2276"]},"institutions":[{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppe Palmieri","raw_affiliation_strings":["Unit of Cancer Genetics, Institute of Biomolecular Chemistry, National Research Council, Sassari, Italy"],"raw_orcid":"https://orcid.org/0000-0002-4350-2276","affiliations":[{"raw_affiliation_string":"Unit of Cancer Genetics, Institute of Biomolecular Chemistry, National Research Council, Sassari, Italy","institution_ids":["https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085788179","display_name":"James J. Goedert","orcid":"https://orcid.org/0000-0001-6134-1472","observed_orcids":["https://orcid.org/0000-0001-6134-1472"]},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James J. Goedert","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA","Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA","institution_ids":["https://openalex.org/I4391012607"]},{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, USA","institution_ids":["https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082372978","display_name":"Junya Fujimoto","orcid":"https://orcid.org/0000-0003-4813-3163","observed_orcids":["https://orcid.org/0000-0003-4813-3163"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Junya Fujimoto","raw_affiliation_strings":["Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA","Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028085268","display_name":"Ignacio Ivan Wistuba","orcid":"https://orcid.org/0000-0003-3365-6340","observed_orcids":["https://orcid.org/0000-0003-3365-6340"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ignacio I. Wistuba","raw_affiliation_strings":["Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA","Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, USA","institution_ids":["https://openalex.org/I1343551460"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5026763137"],"corresponding_institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":{"value":2890,"currency":"USD","value_usd":2890},"fwci":2.5872,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.86426067,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"14","issue":"1","first_page":"3","last_page":"3"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13385","display_name":"Infectious Diseases and Mycology","score":0.9696999788284302,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13385","display_name":"Infectious Diseases and Mycology","score":0.9696999788284302,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.01510000042617321,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.009600000455975533,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/jaagsiekte-sheep-retrovirus","display_name":"Jaagsiekte sheep retrovirus","score":0.9660000205039978},{"id":"https://openalex.org/keywords/lung-cancer","display_name":"lung cancer","score":0.9300000071525574},{"id":"https://openalex.org/keywords/bronchioloalveolar-carcinoma","display_name":"bronchioloalveolar carcinoma","score":0.8230000138282776},{"id":"https://openalex.org/keywords/viral-carcinogenesis","display_name":"viral oncogenesis","score":0.6169999837875366},{"id":"https://openalex.org/keywords/viral-envelope-proteins","display_name":"viral envelope proteins","score":0.8790000081062317},{"id":"https://openalex.org/keywords/neutralizing-antibodies","display_name":"neutralizing antibodies","score":0.7889999747276306},{"id":"https://openalex.org/keywords/sardinia","display_name":"Sardinia","score":0.8560000061988831},{"id":"https://openalex.org/keywords/peru","display_name":"Peru","score":0.7879999876022339}],"concepts":[{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6813631057739258},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.6003247499465942},{"id":"https://openalex.org/C2778431562","wikidata":"https://www.wikidata.org/wiki/Q189308","display_name":"Retrovirus","level":3,"score":0.5745171308517456},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.540091335773468},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5233004689216614},{"id":"https://openalex.org/C91523082","wikidata":"https://www.wikidata.org/wiki/Q420496","display_name":"Antiserum","level":3,"score":0.5100331902503967},{"id":"https://openalex.org/C956191","wikidata":"https://www.wikidata.org/wiki/Q930144","display_name":"Polyclonal antibodies","level":3,"score":0.45650842785835266},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.4373756945133209},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.43564218282699585},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.42261284589767456},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3507733643054962},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3139651119709015},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2136882245540619},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06105819344520569}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000822","descriptor_name":"Animal Husbandry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000914","descriptor_name":"Antibodies, Viral","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000914","descriptor_name":"Antibodies, Viral","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007558","descriptor_name":"Italy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014759","descriptor_name":"Viral Envelope Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D016273","descriptor_name":"Occupational Exposure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022141","descriptor_name":"Jaagsiekte sheep retrovirus","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D022141","descriptor_name":"Jaagsiekte sheep retrovirus","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D057134","descriptor_name":"Antibodies, Neutralizing","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1186/s12977-017-0329-6","doi":"https://doi.org/10.1186/s12977-017-0329-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12977-017-0329-6","pdf_url":"https://retrovirology.biomedcentral.com/track/pdf/10.1186/s12977-017-0329-6","source":{"id":"https://openalex.org/S54115554","display_name":"Retrovirology","issn_l":"1742-4690","issn":["1742-4690"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Retrovirology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4141073","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5248497","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5248497","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5248497","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Retrovirology","raw_type":"Text"},{"id":"pmid:28107820","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28107820","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Retrovirology","raw_type":"Journal Article"},{"id":"pmh:oai:iris.uniss.it:11388/174692","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11388/174692","pdf_url":"https://iris.uniss.it/bitstream/11388/174692/1/2017%20Evidence%20against%20a%20role%20for%20jaagsiekte%20sheep%20retrovirus%20in%20human%20lung%20cancer.pdf","source":{"id":"https://openalex.org/S4306401147","display_name":"UnissResearch (Universit\u00e0 degli Studi di Sassari)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I159650629","host_organization_name":"University of Sassari","host_organization_lineage":["https://openalex.org/I159650629"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.uniss.it:11388/253819","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11388/253819","pdf_url":null,"source":{"id":"https://openalex.org/S4306401147","display_name":"UnissResearch (Universit\u00e0 degli Studi di Sassari)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I159650629","host_organization_name":"University of Sassari","host_organization_lineage":["https://openalex.org/I159650629"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:zaguan.unizar.es:61698","doi":null,"is_oa":true,"landing_page_url":"http://zaguan.unizar.es/record/61698","pdf_url":null,"source":{"id":"https://openalex.org/S4306401812","display_name":"Zaguan (University of Zaragoza Repository)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I255234318","host_organization_name":"Universidad de Zaragoza","host_organization_lineage":["https://openalex.org/I255234318"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1186/s12977-017-0329-6","doi":"https://doi.org/10.1186/s12977-017-0329-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12977-017-0329-6","pdf_url":"https://retrovirology.biomedcentral.com/track/pdf/10.1186/s12977-017-0329-6","source":{"id":"https://openalex.org/S54115554","display_name":"Retrovirology","issn_l":"1742-4690","issn":["1742-4690"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Retrovirology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G2054018460","display_name":"Inhibition of Ebolavirus Entry by IFITM2 Protein","funder_award_id":"R21AI109464","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G293715275","display_name":null,"funder_award_id":"P30-CA-016672","funder_id":"https://openalex.org/F4320332521","funder_display_name":"University of Texas MD Anderson Cancer Center"},{"id":"https://openalex.org/G5746294","display_name":"Targeting Lung Cancer Vulnerabilities","funder_award_id":"P50CA070907","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5822748730","display_name":"IFITM-mediated Inhibition of HIV Infection and Viral Countermeasures","funder_award_id":"R01AI112381","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000878657","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA016672","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320308793","display_name":"Fred Hutchinson Cancer Research Center","ror":"https://ror.org/007ps6h72"},{"id":"https://openalex.org/F4320309374","display_name":"Ohio State University","ror":"https://ror.org/00rs6vg23"},{"id":"https://openalex.org/F4320310094","display_name":"University of Washington","ror":"https://ror.org/00cvxb145"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332521","display_name":"University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2579100141.pdf","grobid_xml":"https://content.openalex.org/works/W2579100141.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W1489777708","https://openalex.org/W1855068291","https://openalex.org/W1877724998","https://openalex.org/W1975719291","https://openalex.org/W1981744882","https://openalex.org/W1989466557","https://openalex.org/W1993972713","https://openalex.org/W1995262441","https://openalex.org/W1999334687","https://openalex.org/W2000425457","https://openalex.org/W2010158037","https://openalex.org/W2011902435","https://openalex.org/W2033760538","https://openalex.org/W2034968383","https://openalex.org/W2042843548","https://openalex.org/W2044296969","https://openalex.org/W2049564643","https://openalex.org/W2049674541","https://openalex.org/W2051824853","https://openalex.org/W2058341317","https://openalex.org/W2061523586","https://openalex.org/W2076882149","https://openalex.org/W2089666196","https://openalex.org/W2091477263","https://openalex.org/W2097061428","https://openalex.org/W2097812689","https://openalex.org/W2103535247","https://openalex.org/W2107214690","https://openalex.org/W2107467160","https://openalex.org/W2129923351","https://openalex.org/W2130590933","https://openalex.org/W2133819228","https://openalex.org/W2137618410","https://openalex.org/W2151379022","https://openalex.org/W2154127160","https://openalex.org/W2165918134","https://openalex.org/W2171095250","https://openalex.org/W2216886337","https://openalex.org/W2251438188"],"related_works":["https://openalex.org/W7096408123","https://openalex.org/W1999103899","https://openalex.org/W1995262441","https://openalex.org/W1855068291","https://openalex.org/W2097061428","https://openalex.org/W2000425457","https://openalex.org/W2089666196","https://openalex.org/W4211095359","https://openalex.org/W1999118565","https://openalex.org/W2130590933"],"abstract_inverted_index":{"BACKGROUND:":[0],"Jaagsiekte":[1],"sheep":[2,11,214,238],"retrovirus":[3],"(JSRV)":[4],"causes":[5],"a":[6,39,55,70,109,141,183,187],"contagious":[7],"lung":[8,62,115,132,155,163,179,188,275],"cancer":[9,63,116,189],"in":[10,64,75,98,113,130,153,162,196,210,228,234,273],"and":[12,58,96,140,218,242,254],"goats":[13],"that":[14,81,194,260],"can":[15,263],"be":[16],"transmitted":[17],"by":[18,21,30,92],"aerosols":[19],"produced":[20],"infected":[22],"animals.":[23,65],"Virus":[24],"entry":[25],"into":[26],"cells":[27],"is":[28,53,59,69,83,216,220,240,244],"initiated":[29],"binding":[31],"of":[32,86,101,128,172,247],"the":[33,49,99,126],"viral":[34],"envelope":[35],"(Env)":[36],"protein":[37,52],"to":[38,148,193,252],"specific":[40],"cell-surface":[41],"receptor,":[42],"Hyal2.":[43],"Unlike":[44],"almost":[45],"all":[46],"other":[47,118],"retroviruses,":[48],"JSRV":[50,74,82,112,129,146,151,157,204,219,243,262,267],"Env":[51,147,158],"also":[54,223],"potent":[56],"oncoprotein":[57],"responsible":[60],"for":[61,73,111,150,225],"Of":[66],"concern,":[67],"Hyal2":[68],"functional":[71],"receptor":[72],"humans.":[76],"RESULTS:":[77],"We":[78,222,258],"show":[79],"here":[80],"fully":[84],"capable":[85],"infecting":[87],"human":[88,103,114,131,154,167,265,274],"cells,":[89,266],"as":[90,178],"measured":[91],"its":[93],"reverse":[94],"transcription":[95],"persistence":[97],"DNA":[100],"cultured":[102],"cells.":[104],"Several":[105],"studies":[106,119],"have":[107],"indicated":[108],"role":[110,127,272],"while":[117,261],"dispute":[120],"these":[121],"results.":[122],"To":[123],"further":[124],"investigate":[125],"cancer,":[133],"we":[134],"used":[135],"highly-specific":[136],"mouse":[137],"monoclonal":[138],"antibodies":[139,227],"rabbit":[142],"polyclonal":[143],"antiserum":[144],"against":[145],"test":[149],"expression":[152,159],"cancer.":[156,276],"was":[160],"undetectable":[161],"cancers":[164],"from":[165,207,230],"128":[166],"subjects,":[168],"including":[169],"73":[170],"cases":[171],"bronchioalveolar":[173],"carcinoma":[174],"(BAC;":[175],"currently":[176],"reclassified":[177],"invasive":[180],"adenocarcinoma":[181],"with":[182,190],"predominant":[184],"lepidic":[185],"component),":[186],"histology":[191],"similar":[192],"found":[195,255],"JSRV-infected":[197],"sheep.":[198],"The":[199],"BAC":[200],"samples":[201,206],"included":[202],"8":[203],"DNA-positive":[205],"subjects":[208],"residing":[209],"Sardinia,":[211],"Italy,":[212],"where":[213,237],"farming":[215,239],"prevalent":[217,241],"present.":[221],"tested":[224],"neutralizing":[226],"sera":[229],"138":[231],"Peruvians":[232],"living":[233],"an":[235],"area":[236],"present,":[245],"24":[246],"whom":[248],"were":[249],"directly":[250],"exposed":[251],"sheep,":[253],"none.":[256],"CONCLUSIONS:":[257],"conclude":[259],"infect":[264],"plays":[268],"little":[269],"if":[270],"any":[271]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2017-01-26T00:00:00"}