{"id":"https://openalex.org/W2578093370","doi":"https://doi.org/10.1128/aem.03001-16","title":"Effects of Lactobacillus plantarum Strain OLL2712 Culture Conditions on the Anti-inflammatory Activities for Murine Immune Cells and Obese and Type 2 Diabetic Mice","display_name":"Effects of Lactobacillus plantarum Strain OLL2712 Culture Conditions on the Anti-inflammatory Activities for Murine Immune Cells and Obese and Type 2 Diabetic Mice","publication_year":2017,"publication_date":"2017-01-14","ids":{"openalex":"https://openalex.org/W2578093370","doi":"https://doi.org/10.1128/aem.03001-16","mag":"2578093370","pmid":"https://pubmed.ncbi.nlm.nih.gov/28087537","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5359495"},"language":"en","primary_location":{"id":"doi:10.1128/aem.03001-16","doi":"https://doi.org/10.1128/aem.03001-16","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aem.03001-16","pdf_url":null,"source":{"id":"https://openalex.org/S158228368","display_name":"Applied and Environmental Microbiology","issn_l":"0099-2240","issn":["0099-2240","1070-6291","1098-5336"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied and Environmental Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5359495","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015850496","display_name":"Takayuki Toshimitsu","orcid":"https://orcid.org/0000-0003-0506-4743","observed_orcids":["https://orcid.org/0000-0003-0506-4743"]},"institutions":[{"id":"https://openalex.org/I4210114911","display_name":"Meiji (Japan)","ror":"https://ror.org/027tjex48","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210114911"]},{"id":"https://openalex.org/I4405273579","display_name":"Meiji Co., Ltd. (Japan)","ror":"https://ror.org/002q6h737","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405273579"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T. Toshimitsu","raw_affiliation_strings":["Lactic Acid Bacteria Research Department, Food Science Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Odawara, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lactic Acid Bacteria Research Department, Food Science Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Odawara, Kanagawa, Japan","institution_ids":["https://openalex.org/I4210114911","https://openalex.org/I4405273579"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032030704","display_name":"Satoru Ozaki","orcid":"https://orcid.org/0000-0002-2322-8804","observed_orcids":["https://orcid.org/0000-0002-2322-8804"]},"institutions":[{"id":"https://openalex.org/I4210114911","display_name":"Meiji (Japan)","ror":"https://ror.org/027tjex48","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210114911"]},{"id":"https://openalex.org/I4405273579","display_name":"Meiji Co., Ltd. (Japan)","ror":"https://ror.org/002q6h737","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405273579"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"S. Ozaki","raw_affiliation_strings":["Lactic Acid Bacteria Research Department, Food Science Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Odawara, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lactic Acid Bacteria Research Department, Food Science Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Odawara, Kanagawa, Japan","institution_ids":["https://openalex.org/I4210114911","https://openalex.org/I4405273579"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J. Mochizuki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114911","display_name":"Meiji (Japan)","ror":"https://ror.org/027tjex48","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210114911"]},{"id":"https://openalex.org/I4405273579","display_name":"Meiji Co., Ltd. (Japan)","ror":"https://ror.org/002q6h737","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405273579"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"J. Mochizuki","raw_affiliation_strings":["Lactic Acid Bacteria Research Department, Food Science Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Odawara, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lactic Acid Bacteria Research Department, Food Science Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Odawara, Kanagawa, Japan","institution_ids":["https://openalex.org/I4210114911","https://openalex.org/I4405273579"]}]},{"author_position":"middle","author":{"id":null,"display_name":"K. Furuichi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114911","display_name":"Meiji (Japan)","ror":"https://ror.org/027tjex48","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210114911"]},{"id":"https://openalex.org/I4405273579","display_name":"Meiji Co., Ltd. (Japan)","ror":"https://ror.org/002q6h737","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405273579"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K. Furuichi","raw_affiliation_strings":["Lactic Acid Bacteria Research Department, Food Science Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Odawara, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lactic Acid Bacteria Research Department, Food Science Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Odawara, Kanagawa, Japan","institution_ids":["https://openalex.org/I4210114911","https://openalex.org/I4405273579"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027552604","display_name":"Yukio Asami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114911","display_name":"Meiji (Japan)","ror":"https://ror.org/027tjex48","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210114911"]},{"id":"https://openalex.org/I4405273579","display_name":"Meiji Co., Ltd. (Japan)","ror":"https://ror.org/002q6h737","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405273579"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y. Asami","raw_affiliation_strings":["Lactic Acid Bacteria Research Department, Food Science Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Odawara, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lactic Acid Bacteria Research Department, Food Science Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Odawara, Kanagawa, Japan","institution_ids":["https://openalex.org/I4210114911","https://openalex.org/I4405273579"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.9226,"has_fulltext":false,"cited_by_count":49,"citation_normalized_percentile":{"value":0.93922447,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"83","issue":"7","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lactic-acid-bacteria","display_name":"lactic acid bacteria","score":0.890999972820282},{"id":"https://openalex.org/keywords/culture-conditions","display_name":"culture conditions","score":0.9359999895095825},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.9419999718666077},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.878000020980835},{"id":"https://openalex.org/keywords/il-12","display_name":"IL-12","score":0.9950000047683716},{"id":"https://openalex.org/keywords/tlr2","display_name":"TLR2","score":0.8700000047683716},{"id":"https://openalex.org/keywords/bacterial-growth-phase","display_name":"bacterial growth phase","score":0.777999997138977},{"id":"https://openalex.org/keywords/exponential-phase","display_name":"exponential growth phase","score":0.5429999828338623},{"id":"https://openalex.org/keywords/stationary-phase","display_name":"stationary phase","score":0.7379999756813049},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.8069999814033508},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8500000238418579},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9909999966621399},{"id":"https://openalex.org/keywords/metabolic-disorders","display_name":"metabolic disorders","score":0.7929999828338623},{"id":"https://openalex.org/keywords/probiotics","display_name":"probiotics","score":0.5870000123977661}],"concepts":[{"id":"https://openalex.org/C2778985185","wikidata":"https://www.wikidata.org/wiki/Q1756682","display_name":"Lactobacillus plantarum","level":4,"score":0.7656362652778625},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6819839477539062},{"id":"https://openalex.org/C2781236682","wikidata":"https://www.wikidata.org/wiki/Q410015","display_name":"TLR2","level":4,"score":0.6292932629585266},{"id":"https://openalex.org/C2775920511","wikidata":"https://www.wikidata.org/wiki/Q161249","display_name":"Lactic acid","level":3,"score":0.5646271705627441},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5206031799316406},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5019283294677734},{"id":"https://openalex.org/C2780206646","wikidata":"https://www.wikidata.org/wiki/Q1061596","display_name":"Lactobacillus","level":3,"score":0.4979100227355957},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.47933587431907654},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.45914456248283386},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.44052332639694214},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.434021532535553},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.28280818462371826},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.15013426542282104},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.10622939467430115},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003470","descriptor_name":"Culture Media","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016753","descriptor_name":"Interleukin-10","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D016753","descriptor_name":"Interleukin-10","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D016753","descriptor_name":"Interleukin-10","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018664","descriptor_name":"Interleukin-12","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D018664","descriptor_name":"Interleukin-12","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D018664","descriptor_name":"Interleukin-12","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D019936","descriptor_name":"Probiotics","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D048191","descriptor_name":"Lactiplantibacillus plantarum","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D048191","descriptor_name":"Lactiplantibacillus plantarum","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051195","descriptor_name":"Toll-Like Receptor 2","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056747","descriptor_name":"Immunomodulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/aem.03001-16","doi":"https://doi.org/10.1128/aem.03001-16","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aem.03001-16","pdf_url":null,"source":{"id":"https://openalex.org/S158228368","display_name":"Applied and Environmental Microbiology","issn_l":"0099-2240","issn":["0099-2240","1070-6291","1098-5336"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied and Environmental Microbiology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4527707","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5359495","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5359495","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5359495","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Appl Environ Microbiol","raw_type":"Text"},{"id":"pmid:28087537","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28087537","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied and environmental microbiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4527707","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5359495","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1490738040","https://openalex.org/W1578635659","https://openalex.org/W1816588801","https://openalex.org/W1839424012","https://openalex.org/W1922734004","https://openalex.org/W1965312946","https://openalex.org/W1986956544","https://openalex.org/W1996596574","https://openalex.org/W2000662037","https://openalex.org/W2005346356","https://openalex.org/W2012563097","https://openalex.org/W2017290044","https://openalex.org/W2021240627","https://openalex.org/W2035272505","https://openalex.org/W2058149303","https://openalex.org/W2060839471","https://openalex.org/W2069973024","https://openalex.org/W2073336487","https://openalex.org/W2091990208","https://openalex.org/W2106629036","https://openalex.org/W2106684817","https://openalex.org/W2125790188","https://openalex.org/W2127136381","https://openalex.org/W2129280927","https://openalex.org/W2132241088","https://openalex.org/W2139754661","https://openalex.org/W2141125135","https://openalex.org/W2143544846","https://openalex.org/W2145697808","https://openalex.org/W2148920412","https://openalex.org/W2149659037","https://openalex.org/W2151683769","https://openalex.org/W2160236340","https://openalex.org/W2165246814","https://openalex.org/W2171308297","https://openalex.org/W2194399967"],"related_works":["https://openalex.org/W2194399967","https://openalex.org/W4313533717","https://openalex.org/W2990135960","https://openalex.org/W2073336487","https://openalex.org/W1973801317","https://openalex.org/W2166236498","https://openalex.org/W301920021","https://openalex.org/W4210559828","https://openalex.org/W2339088226","https://openalex.org/W4385514375"],"abstract_inverted_index":{"ABSTRACT":[0],"Studies":[1],"on":[2,35,81,130,161],"the":[3,18,28,75,119,179,193,205,237,274],"health-promoting":[4,238],"effects":[5,47,160],"of":[6,17,30,78,126,181,196,221,240,276],"lactic":[7,197],"acid":[8,198],"bacteria":[9,199],"(LAB)":[10],"are":[11],"numerous,":[12],"but":[13],"few":[14,201],"provide":[15],"examples":[16],"relationship":[19,206],"between":[20,87,207],"LAB":[21,211,258,277],"function":[22],"and":[23,45,55,94,101,158,163,210],"culture":[24,33,69,92,97,131,144,176,190,208,219,233,259,268],"conditions.":[25,70],"We":[26,51,116,138,229],"verified":[27],"effect":[29],"differences":[31,142],"in":[32,58,133,146,242],"conditions":[34,132,177,191,209,220,234,260],"Lactobacillus":[36,222],"plantarum":[37,223],"OLL2712":[38,64,79,88,127,149,224,241],"functionality;":[39],"this":[40,214],"strain":[41],"exhibits":[42],"anti-inflammatory":[43,156,182,227,279],"activity":[44,112,125,157],"preventive":[46],"against":[48,246],"metabolic":[49,247],"disorders.":[50,248],"measured":[52],"interleukin-10":[53],"(IL-10)":[54],"IL-12":[56],"production":[57,275],"murine":[59,82],"immune":[60,83],"cells":[61,65,80,84,107,128,150],"treated":[62],"with":[63,135,278],"prepared":[66],"under":[67],"various":[68],"The":[71],"results":[72,173,265],"showed":[73,231],"that":[74,118,175,189,232,267],"IL-10-inducing":[76,111,136],"activities":[77],"differed":[85],"dramatically":[86],"groups":[89],"at":[90,151],"different":[91,96],"phases":[93,145],"using":[95],"medium":[98],"components,":[99],"temperatures,":[100],"neutralizing":[102],"pHs.":[103],"In":[104,213],"particular,":[105],"exponential-phase":[106],"had":[108,154],"much":[109],"more":[110,155],"than":[113,166],"stationary-phase":[114,170],"cells.":[115],"confirmed":[117],"Toll-like":[120],"receptor":[121],"2":[122],"(TLR2)":[123],"stimulation":[124],"depended":[129],"conjunction":[134],"activity.":[137,228,280],"also":[139,230],"demonstrated":[140,188,217],"functional":[141],"by":[143,168,255],"vivo":[147,243],";":[148],"exponential":[152],"phase":[153],"anti-metabolic-disorder":[159],"obese":[162],"diabetic":[164],"mice":[165],"those":[167],"their":[169],"counterparts.":[171],"These":[172],"suggest":[174,266],"affect":[178],"functionality":[180],"LAB.":[183],"IMPORTANCE":[184],"While":[185],"previous":[186],"studies":[187],"affected":[192,261],"immunomodulatory":[194,262],"properties":[195],"(LAB),":[200],"have":[202],"comprehensively":[203],"investigated":[204],"functionality.":[212],"study,":[215],"we":[216,250],"several":[218],"for":[225,273],"higher":[226],"concretely":[235],"influenced":[236],"functions":[239],",":[244],"particularly":[245],"Further,":[249],"characterized":[251],"a":[252],"novel":[253],"mechanism":[254],"which":[256],"changing":[257],"properties.":[263],"Our":[264],"condition":[269],"optimization":[270],"is":[271],"important":[272]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2017-01-26T00:00:00"}