{"id":"https://openalex.org/W2575233190","doi":"https://doi.org/10.1200/jco.2016.34.2_suppl.161","title":"Diagnostic capability of prostate multiparametric magnetic resonance in prediction of cancer and histological grade.","display_name":"Diagnostic capability of prostate multiparametric magnetic resonance in prediction of cancer and histological grade.","publication_year":2016,"publication_date":"2016-01-10","ids":{"openalex":"https://openalex.org/W2575233190","doi":"https://doi.org/10.1200/jco.2016.34.2_suppl.161","mag":"2575233190"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2016.34.2_suppl.161","doi":"https://doi.org/10.1200/jco.2016.34.2_suppl.161","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2016.34.2_suppl.161","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://repositorio.uchile.cl/handle/2250/141365","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088374422","display_name":"Jaime Antonio Altamirano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140602","display_name":"Fundaci\u00f3n Arturo L\u00f3pez P\u00e9rez","ror":"https://ror.org/03r4w0b84","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210140602"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Jaime Antonio Altamirano","raw_affiliation_strings":["FALP, Providencia, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"FALP, Providencia, Chile","institution_ids":["https://openalex.org/I4210140602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103801083","display_name":"Ivan Federico Pinto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140602","display_name":"Fundaci\u00f3n Arturo L\u00f3pez P\u00e9rez","ror":"https://ror.org/03r4w0b84","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210140602"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Ivan Federico Pinto","raw_affiliation_strings":["Instituto Oncol\u00f3gico FALP, Santiago, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Oncol\u00f3gico FALP, Santiago, Chile","institution_ids":["https://openalex.org/I4210140602"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Maria Jesus Quiroz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Maria Jesus Quiroz","raw_affiliation_strings":["Facultad de Medicina Universidad de Chile, Santiago, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Facultad de Medicina Universidad de Chile, Santiago, Chile","institution_ids":["https://openalex.org/I69737025"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jorge Gonzalo Diaz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140602","display_name":"Fundaci\u00f3n Arturo L\u00f3pez P\u00e9rez","ror":"https://ror.org/03r4w0b84","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210140602"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Jorge Gonzalo Diaz","raw_affiliation_strings":["Instituto Oncol\u00f3gico FALP, Santiago, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Oncol\u00f3gico FALP, Santiago, Chile","institution_ids":["https://openalex.org/I4210140602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066796860","display_name":"Mauricio Canals","orcid":"https://orcid.org/0000-0001-5256-4439","observed_orcids":["https://orcid.org/0000-0001-5256-4439"]},"institutions":[{"id":"https://openalex.org/I4210140602","display_name":"Fundaci\u00f3n Arturo L\u00f3pez P\u00e9rez","ror":"https://ror.org/03r4w0b84","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210140602"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Mauricio Canals","raw_affiliation_strings":["Instituto Oncol\u00f3gico FALP, Santiago, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Oncol\u00f3gico FALP, Santiago, Chile","institution_ids":["https://openalex.org/I4210140602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110112032","display_name":"Roberto Mauricio Vilches","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140602","display_name":"Fundaci\u00f3n Arturo L\u00f3pez P\u00e9rez","ror":"https://ror.org/03r4w0b84","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210140602"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Roberto Mauricio Vilches","raw_affiliation_strings":["Instituto Oncologico FALP, \u00d1u\u00f1oa, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Oncologico FALP, \u00d1u\u00f1oa, Chile","institution_ids":["https://openalex.org/I4210140602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087728149","display_name":"Camilo Sandoval","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140602","display_name":"Fundaci\u00f3n Arturo L\u00f3pez P\u00e9rez","ror":"https://ror.org/03r4w0b84","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210140602"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Camilo Sandoval","raw_affiliation_strings":["Instituto Oncol\u00f3gico FALP, Las Condes, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Oncol\u00f3gico FALP, Las Condes, Chile","institution_ids":["https://openalex.org/I4210140602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051934691","display_name":"Alvaro Daniel Vidal","orcid":"https://orcid.org/0000-0003-0699-7879","observed_orcids":["https://orcid.org/0000-0003-0699-7879"]},"institutions":[{"id":"https://openalex.org/I4210140602","display_name":"Fundaci\u00f3n Arturo L\u00f3pez P\u00e9rez","ror":"https://ror.org/03r4w0b84","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210140602"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Alvaro Daniel Vidal","raw_affiliation_strings":["Instituto Oncol\u00f3gico FALP, Providencia, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Oncol\u00f3gico FALP, Providencia, Chile","institution_ids":["https://openalex.org/I4210140602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019129151","display_name":"Alejandro Rojas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I162148367","display_name":"Pontificia Universidad Cat\u00f3lica de Chile","ror":"https://ror.org/04teye511","country_code":"CL","type":"education","lineage":["https://openalex.org/I162148367"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Alejandro Rojas","raw_affiliation_strings":["Facultad de Medicina Universidad Cat\u00f3lica de Chile, Santiago, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Facultad de Medicina Universidad Cat\u00f3lica de Chile, Santiago, Chile","institution_ids":["https://openalex.org/I162148367"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083465810","display_name":"Crist\u00f3bal Rom\u00e1n","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140602","display_name":"Fundaci\u00f3n Arturo L\u00f3pez P\u00e9rez","ror":"https://ror.org/03r4w0b84","country_code":"CL","type":"healthcare","lineage":["https://openalex.org/I4210140602"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Cristobal Roman","raw_affiliation_strings":["Instituto Oncol\u00f3gico FALP, Santiago, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Oncol\u00f3gico FALP, Santiago, Chile","institution_ids":["https://openalex.org/I4210140602"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"34","issue":"2_suppl","first_page":"161","last_page":"161"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.011099999770522118,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.7480000257492065},{"id":"https://openalex.org/keywords/multiparametric-mri","display_name":"multiparametric MRI","score":0.9570000171661377},{"id":"https://openalex.org/keywords/gleason-score","display_name":"Gleason score","score":0.7590000033378601},{"id":"https://openalex.org/keywords/cancer-risk-prediction","display_name":"cancer risk prediction","score":0.5830000042915344},{"id":"https://openalex.org/keywords/diffusion-weighted-imaging","display_name":"diffusion-weighted imaging","score":0.7200000286102295},{"id":"https://openalex.org/keywords/dynamic-contrast-enhanced-mri","display_name":"dynamic contrast-enhanced MRI","score":0.972000002861023},{"id":"https://openalex.org/keywords/t2-weighted-imaging","display_name":"T2-weighted imaging","score":0.8619999885559082},{"id":"https://openalex.org/keywords/pi-rads","display_name":"PI-RADS","score":0.8629999756813049},{"id":"https://openalex.org/keywords/transrectal-ultrasound-guided-biopsy","display_name":"transrectal ultrasound-guided biopsy","score":0.8209999799728394},{"id":"https://openalex.org/keywords/histological-grade","display_name":"histological grade","score":0.5450000166893005}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8773117065429688},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.8167507648468018},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.6468629240989685},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.5948346853256226},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.5934086441993713},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5569267868995667},{"id":"https://openalex.org/C2910607126","wikidata":"https://www.wikidata.org/wiki/Q48790829","display_name":"Multiparametric MRI","level":4,"score":0.513454258441925},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.477845162153244},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.4454006850719452},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.440067857503891},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.43959206342697144},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.42245370149612427},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3879563808441162},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.33451664447784424},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27172529697418213}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1200/jco.2016.34.2_suppl.161","doi":"https://doi.org/10.1200/jco.2016.34.2_suppl.161","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2016.34.2_suppl.161","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},{"id":"pmh:oai:repositorio.uchile.cl:2250/141365","doi":null,"is_oa":true,"landing_page_url":"http://repositorio.uchile.cl/handle/2250/141365","pdf_url":null,"source":{"id":"https://openalex.org/S4306481413","display_name":"Universidad de Chile","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Clinical Oncology","raw_type":"Art\u00edculo de revista"}],"best_oa_location":{"id":"pmh:oai:repositorio.uchile.cl:2250/141365","doi":null,"is_oa":true,"landing_page_url":"http://repositorio.uchile.cl/handle/2250/141365","pdf_url":null,"source":{"id":"https://openalex.org/S4306481413","display_name":"Universidad de Chile","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Clinical Oncology","raw_type":"Art\u00edculo de revista"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2574165244","https://openalex.org/W1994158295","https://openalex.org/W2121547174","https://openalex.org/W1971237277","https://openalex.org/W2048726822","https://openalex.org/W2992439187","https://openalex.org/W2733517570","https://openalex.org/W3037371610","https://openalex.org/W3133453251","https://openalex.org/W2739390283"],"abstract_inverted_index":{"161":[0],"Background:":[1],"The":[2,19,76,147,185,240],"prostatic":[3],"multiparametric":[4],"MRI":[5],"(mpMRI)":[6],"can":[7],"enhance":[8],"the":[9,12,27,52,63,66,74,107,129,175,181,218,252],"performance":[10],"of":[11,21,29,68,85,109,140,170,206,230,235],"prostate":[13,36,265],"core":[14],"biopsy":[15,48,282],"to":[16,25,31,44,51,237],"detect":[17],"cancer.":[18,37,211],"objective":[20],"this":[22,276],"study":[23],"is":[24,242],"assess":[26],"capability":[28],"MpMRI":[30,41,241],"identify":[32],"high-":[33,262],"and":[34,57,65,70,83,120,161,180,204,209,255,263],"intermediate-risk":[35,264],"Methods:":[38],"Prospective":[39],"cohort.":[40],"was":[42,94,117,135,178,183,188,220],"performed":[43,95,119],"patients":[45,127,142],"with":[46,96,251,283],"TRUS-guided":[47,281],"indication":[49],"prior":[50],"biopsy.":[53,75],"Diffusion,":[54],"PIRADS,":[55],"DCE":[56],"T2":[58],"parameters":[59,226,271],"were":[60,78,143],"observed":[61],"on":[62,73,106,275],"MRI,":[64],"presence":[67,84],"cancer":[69,86,266],"Gleason":[71,87,144,232],"score":[72,145,169,234],"results":[77],"divided":[79],"between":[80,202],"no":[81],"cancer,":[82],"6":[88,233],"or":[89,173,223,269],"higher.":[90],"Logistic":[91],"regression":[92,116],"test":[93,259],"a":[97,168,200,228,243],"95%":[98],"confidence":[99],"interval.":[100],"We":[101,192],"assigned":[102],"different":[103],"values,":[104],"depending":[105],"importance":[108],"each":[110],"factor,":[111],"applying":[112],"binominal":[113],"regression.":[114],"Ordinal":[115],"then":[118],"Odds":[121],"ratio":[122],"calculated.":[123],"Results:":[124],"Seventy":[125],"three":[126],"met":[128],"described":[130],"criteria.":[131],"Cancer":[132],"detection":[133],"rate":[134],"60.27%":[136],"(44":[137],"patients).":[138],"Seventeen":[139],"these":[141],"six.":[146],"calculated":[148,176,193],"score,":[149],"gave":[150],"7":[151],"points":[152,157,163,172],"for":[153,158,164,260],"altered":[154,159,165,197,216,225,285],"T2,":[155],"8":[156],"diffusion":[160],"5":[162],"DCE.":[166],"With":[167,212],"12":[171],"more,":[174],"sensibility":[177],"84,62%":[179],"specificity":[182],"41.18%.":[184],"estimated":[186],"OR":[187],"1.15":[189],"[IC":[190],"1-1.38].":[191],"that":[194],"having":[195,207,231],"one":[196,215],"parameter,":[198,217],"had":[199],"probability":[201,219,229],"0.17":[203],"0.25":[205],"intermediate":[208],"high-risk":[210],"more":[213,224,270],"than":[214],"0.37.":[221],"One":[222],"gives":[227],"0.20":[236],"0.25.":[238],"Conclusions:":[239],"useful":[244],"tool":[245],"because":[246],"it":[247],"has":[248],"high":[249],"correlation":[250],"histological":[253],"grade,":[254],"it\u00b4s":[256],"an":[257,284],"excellent":[258],"predicting":[261],"when":[267],"two":[268],"are":[272],"altered.":[273],"Based":[274],"findings":[277],"we":[278],"strongly":[279],"suggest":[280],"MpMRI.":[286]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2017-01-26T00:00:00"}