{"id":"https://openalex.org/W2575229100","doi":"https://doi.org/10.1016/j.actbio.2017.01.036","title":"Cell-laden hydrogels for osteochondral and cartilage tissue engineering","display_name":"Cell-laden hydrogels for osteochondral and cartilage tissue engineering","publication_year":2017,"publication_date":"2017-01-11","ids":{"openalex":"https://openalex.org/W2575229100","doi":"https://doi.org/10.1016/j.actbio.2017.01.036","mag":"2575229100","pmid":"https://pubmed.ncbi.nlm.nih.gov/28088667","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5545789"},"language":"en","primary_location":{"id":"doi:10.1016/j.actbio.2017.01.036","doi":"https://doi.org/10.1016/j.actbio.2017.01.036","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.actbio.2017.01.036","pdf_url":null,"source":{"id":"https://openalex.org/S173145877","display_name":"Acta Biomaterialia","issn_l":"1742-7061","issn":["1742-7061","1878-7568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Acta Biomaterialia","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.actbio.2017.01.036","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054793325","display_name":"Jingzhou Yang","orcid":"https://orcid.org/0000-0003-1687-4389","observed_orcids":["https://orcid.org/0000-0003-1687-4389","https://orcid.org/0000-0001-7395-3396"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I4210105982","display_name":"Guangzhou Women and Children Medical Center","ror":"https://ror.org/01g53at17","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105982"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Jingzhou Yang","raw_affiliation_strings":["Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Guangzhou Women and Children's Medical Center, Sun Yat-sen University, Guangzhou 510623, Guangdong, People's Republic of China","Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA","Guangzhou Women and Children\u2019s Medical Center, Sun Yat-sen University, Guangzhou 510623, Guangdong, People's Republic of China","Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Guangzhou Women and Children's Medical Center, Sun Yat-sen University, Guangzhou 510623, Guangdong, People's Republic of China","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I157773358","https://openalex.org/I4210092658","https://openalex.org/I4210105982","https://openalex.org/I63966007"]},{"raw_affiliation_string":"Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Guangzhou Women and Children\u2019s Medical Center, Sun Yat-sen University, Guangzhou 510623, Guangdong, People's Republic of China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210105982"]},{"raw_affiliation_string":"Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA","institution_ids":["https://openalex.org/I4210092658","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067842712","display_name":"Yu Shrike Zhang","orcid":"https://orcid.org/0000-0002-0045-0808","observed_orcids":["https://orcid.org/0000-0002-0045-0808","https://orcid.org/0000-0002-2291-2022"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yu Shrike Zhang","raw_affiliation_strings":["Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA","Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA","Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210092658","https://openalex.org/I63966007"]},{"raw_affiliation_string":"Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA","institution_ids":["https://openalex.org/I4210092658","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059506493","display_name":"Kan Yue","orcid":"https://orcid.org/0000-0003-1450-0279","observed_orcids":["https://orcid.org/0000-0003-1450-0279"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kan Yue","raw_affiliation_strings":["Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA","Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA","Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210092658","https://openalex.org/I63966007"]},{"raw_affiliation_string":"Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA","institution_ids":["https://openalex.org/I4210092658","https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033056518","display_name":"Ali Khademhosseini","orcid":"https://orcid.org/0000-0002-2692-1524","observed_orcids":["https://orcid.org/0000-0002-2692-1524","https://orcid.org/0000-0001-6322-8852"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I185163786","display_name":"King Abdulaziz University","ror":"https://ror.org/02ma4wv74","country_code":"SA","type":"education","lineage":["https://openalex.org/I185163786"]},{"id":"https://openalex.org/I24062138","display_name":"Konkuk University","ror":"https://ror.org/025h1m602","country_code":"KR","type":"education","lineage":["https://openalex.org/I24062138"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["KR","SA","US"],"is_corresponding":true,"raw_author_name":"Ali Khademhosseini","raw_affiliation_strings":["Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Bioindustrial Technologies, College of Animal Bioscience and Technology, Konkuk University, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea; Department of Physics, King Abdulaziz University, Jeddah 21569, Saudi Arabia. Electronic address: alik@bwh.harvard.edu","Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA","Department of Bioindustrial Technologies, College of Animal Bioscience and Technology, Konkuk University, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea","Department of Physics, King Abdulaziz University, Jeddah 21569, Saudi Arabia","Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Bioindustrial Technologies, College of Animal Bioscience and Technology, Konkuk University, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea; Department of Physics, King Abdulaziz University, Jeddah 21569, Saudi Arabia. Electronic address: alik@bwh.harvard.edu","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I185163786","https://openalex.org/I24062138","https://openalex.org/I4210092658","https://openalex.org/I63966007"]},{"raw_affiliation_string":"Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Bioindustrial Technologies, College of Animal Bioscience and Technology, Konkuk University, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea","institution_ids":["https://openalex.org/I24062138"]},{"raw_affiliation_string":"Department of Physics, King Abdulaziz University, Jeddah 21569, Saudi Arabia","institution_ids":["https://openalex.org/I185163786"]},{"raw_affiliation_string":"Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA","institution_ids":["https://openalex.org/I4210092658","https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5033056518"],"corresponding_institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I185163786","https://openalex.org/I24062138","https://openalex.org/I4210092658","https://openalex.org/I63966007"],"apc_list":{"value":3810,"currency":"USD","value_usd":3810},"apc_paid":null,"fwci":3.8655,"has_fulltext":false,"cited_by_count":665,"citation_normalized_percentile":{"value":0.96699267,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"57","issue":null,"first_page":"1","last_page":"25"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.8187999725341797,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.8187999725341797,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.07980000227689743,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.044599998742341995,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cell-laden-hydrogels","display_name":"cell-laden hydrogels","score":0.9980000257492065},{"id":"https://openalex.org/keywords/osteochondral-tissue-engineering","display_name":"osteochondral tissue engineering","score":0.9610000252723694},{"id":"https://openalex.org/keywords/articular-cartilage-repair","display_name":"articular cartilage repair","score":0.8259999752044678},{"id":"https://openalex.org/keywords/chondrogenesis","display_name":"chondrogenesis","score":0.8149999976158142},{"id":"https://openalex.org/keywords/bone-formation","display_name":"bone formation","score":0.9980000257492065},{"id":"https://openalex.org/keywords/growth-factor-delivery","display_name":"growth factor delivery","score":0.9340000152587891},{"id":"https://openalex.org/keywords/3d-bioprinting","display_name":"3D bioprinting","score":0.8799999952316284},{"id":"https://openalex.org/keywords/cartilage-defects","display_name":"cartilage defects","score":0.5490000247955322}],"concepts":[{"id":"https://openalex.org/C108586683","wikidata":"https://www.wikidata.org/wiki/Q17164826","display_name":"Self-healing hydrogels","level":2,"score":0.8784615993499756},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.7234647870063782},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6852338314056396},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.678004264831543},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.5151968598365784},{"id":"https://openalex.org/C3020332539","wikidata":"https://www.wikidata.org/wiki/Q2014564","display_name":"Articular cartilage","level":4,"score":0.46620452404022217},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.1604054570198059},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.16014528274536133},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.13497766852378845},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1073780357837677},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10135963559150696},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.09820523858070374},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.06645917892456055},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010012","descriptor_name":"Osteogenesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020100","descriptor_name":"Hydrogels","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D020219","descriptor_name":"Chondrogenesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.actbio.2017.01.036","doi":"https://doi.org/10.1016/j.actbio.2017.01.036","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.actbio.2017.01.036","pdf_url":null,"source":{"id":"https://openalex.org/S173145877","display_name":"Acta Biomaterialia","issn_l":"1742-7061","issn":["1742-7061","1878-7568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Acta Biomaterialia","raw_type":"journal-article"},{"id":"pmid:28088667","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28088667","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta biomaterialia","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:4997632","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5545789","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5545789","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5545789","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Acta Biomater","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.actbio.2017.01.036","doi":"https://doi.org/10.1016/j.actbio.2017.01.036","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.actbio.2017.01.036","pdf_url":null,"source":{"id":"https://openalex.org/S173145877","display_name":"Acta Biomaterialia","issn_l":"1742-7061","issn":["1742-7061","1878-7568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Acta Biomaterialia","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.428600013256073,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3152866314","display_name":"A miniaturized model of human skin and lymph node for drug discovery and testing","funder_award_id":"R56AI105024","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G317693313","display_name":"A Microfabrication Platform for Direct Printing Vascularized Functional Tissue Co","funder_award_id":"R01EB012597","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G4219809854","display_name":"Engineering Vascularized Bone Tissues By Microfabrication And Scaffolding","funder_award_id":"R01DE021468","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G5762996224","display_name":"EFRI-BioFLEX: Tissue Engineered Flexible Sensors, Actuators and Electronics for Chronic Wound Management","funder_award_id":"1240443","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G6190129805","display_name":"Microengineered Osteons for Bone Tissue Engineering","funder_award_id":"R01AR057837","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G7117515226","display_name":"3D combinatorial microenvironments for effective cell based therapy","funder_award_id":"R01HL099073","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8270734711","display_name":"Microengineered Osteoinductive and Vasculogenic Scaffold","funder_award_id":"R56AR063745","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"},{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":317,"referenced_works":["https://openalex.org/W66896058","https://openalex.org/W88047033","https://openalex.org/W299149974","https://openalex.org/W1120477740","https://openalex.org/W1495044187","https://openalex.org/W1499137675","https://openalex.org/W1502207071","https://openalex.org/W1505843546","https://openalex.org/W1514702387","https://openalex.org/W1535380624","https://openalex.org/W1541101179","https://openalex.org/W1560201504","https://openalex.org/W1564442748","https://openalex.org/W1728059589","https://openalex.org/W1795702683","https://openalex.org/W1901258766","https://openalex.org/W1921474434","https://openalex.org/W1923710437","https://openalex.org/W1962023711","https://openalex.org/W1963613524","https://openalex.org/W1964207157","https://openalex.org/W1964744563","https://openalex.org/W1964798096","https://openalex.org/W1965628287","https://openalex.org/W1966504316","https://openalex.org/W1968359010","https://openalex.org/W1968822620","https://openalex.org/W1970368333","https://openalex.org/W1971500643","https://openalex.org/W1971964281","https://openalex.org/W1972460098","https://openalex.org/W1974638778","https://openalex.org/W1974897852","https://openalex.org/W1975045353","https://openalex.org/W1975207418","https://openalex.org/W1976365868","https://openalex.org/W1976454147","https://openalex.org/W1977234663","https://openalex.org/W1977737380","https://openalex.org/W1978173381","https://openalex.org/W1980560357","https://openalex.org/W1980631211","https://openalex.org/W1984620261","https://openalex.org/W1985689735","https://openalex.org/W1985723207","https://openalex.org/W1987087659","https://openalex.org/W1988741595","https://openalex.org/W1989444744","https://openalex.org/W1989739945","https://openalex.org/W1989975809","https://openalex.org/W1989978553","https://openalex.org/W1990249097","https://openalex.org/W1992442994","https://openalex.org/W1992594866","https://openalex.org/W1992696273","https://openalex.org/W1993700548","https://openalex.org/W1993818347","https://openalex.org/W1994048411","https://openalex.org/W1994898751","https://openalex.org/W1994903148","https://openalex.org/W1995499476","https://openalex.org/W1997212355","https://openalex.org/W1997346678","https://openalex.org/W1997429761","https://openalex.org/W1998157485","https://openalex.org/W1998961294","https://openalex.org/W1999638634","https://openalex.org/W2000031847","https://openalex.org/W2000209705","https://openalex.org/W2001952131","https://openalex.org/W2003330618","https://openalex.org/W2004290723","https://openalex.org/W2005424476","https://openalex.org/W2006262006","https://openalex.org/W2007476414","https://openalex.org/W2007851955","https://openalex.org/W2007898091","https://openalex.org/W2008315456","https://openalex.org/W2008626012","https://openalex.org/W2010439076","https://openalex.org/W2011038175","https://openalex.org/W2011982118","https://openalex.org/W2012044194","https://openalex.org/W2012333093","https://openalex.org/W2013344742","https://openalex.org/W2014053740","https://openalex.org/W2014264391","https://openalex.org/W2015396326","https://openalex.org/W2015668670","https://openalex.org/W2016654090","https://openalex.org/W2017254150","https://openalex.org/W2018151517","https://openalex.org/W2020342708","https://openalex.org/W2020700245","https://openalex.org/W2020787517","https://openalex.org/W2021324974","https://openalex.org/W2021516914","https://openalex.org/W2021550972","https://openalex.org/W2022356720","https://openalex.org/W2022836746","https://openalex.org/W2023474734","https://openalex.org/W2025612961","https://openalex.org/W2025827978","https://openalex.org/W2025898370","https://openalex.org/W2026425833","https://openalex.org/W2026757718","https://openalex.org/W2027192227","https://openalex.org/W2027239520","https://openalex.org/W2028509138","https://openalex.org/W2029723752","https://openalex.org/W2029729635","https://openalex.org/W2029950779","https://openalex.org/W2030995864","https://openalex.org/W2031500555","https://openalex.org/W2032393093","https://openalex.org/W2033391292","https://openalex.org/W2033592937","https://openalex.org/W2034650092","https://openalex.org/W2034792467","https://openalex.org/W2034799871","https://openalex.org/W2035752329","https://openalex.org/W2036862827","https://openalex.org/W2036924614","https://openalex.org/W2038331445","https://openalex.org/W2038611660","https://openalex.org/W2038987199","https://openalex.org/W2039167655","https://openalex.org/W2039813962","https://openalex.org/W2040035248","https://openalex.org/W2040249570","https://openalex.org/W2040662965","https://openalex.org/W2040812466","https://openalex.org/W2042876113","https://openalex.org/W2043669923","https://openalex.org/W2045095867","https://openalex.org/W2045295282","https://openalex.org/W2046688088","https://openalex.org/W2046990574","https://openalex.org/W2047134067","https://openalex.org/W2048644480","https://openalex.org/W2048993028","https://openalex.org/W2049002990","https://openalex.org/W2049762522","https://openalex.org/W2049791410","https://openalex.org/W2050363987","https://openalex.org/W2052116137","https://openalex.org/W2053868595","https://openalex.org/W2053911973","https://openalex.org/W2054250836","https://openalex.org/W2054544903","https://openalex.org/W2056691205","https://openalex.org/W2057198306","https://openalex.org/W2058621622","https://openalex.org/W2059403602","https://openalex.org/W2059567868","https://openalex.org/W2059912755","https://openalex.org/W2060112963","https://openalex.org/W2060410041","https://openalex.org/W2060718794","https://openalex.org/W2060884060","https://openalex.org/W2061073787","https://openalex.org/W2061245480","https://openalex.org/W2061733341","https://openalex.org/W2062279390","https://openalex.org/W2062498918","https://openalex.org/W2063100081","https://openalex.org/W2064364366","https://openalex.org/W2064707228","https://openalex.org/W2064939106","https://openalex.org/W2065386894","https://openalex.org/W2066256262","https://openalex.org/W2066966685","https://openalex.org/W2067662578","https://openalex.org/W2067885678","https://openalex.org/W2069025518","https://openalex.org/W2069636884","https://openalex.org/W2069822613","https://openalex.org/W2071236789","https://openalex.org/W2072087534","https://openalex.org/W2072188965","https://openalex.org/W2072339743","https://openalex.org/W2073241345","https://openalex.org/W2074086931","https://openalex.org/W2075580027","https://openalex.org/W2075927574","https://openalex.org/W2077388592","https://openalex.org/W2077713404","https://openalex.org/W2078120593","https://openalex.org/W2078261756","https://openalex.org/W2078965873","https://openalex.org/W2079082206","https://openalex.org/W2079827923","https://openalex.org/W2080868522","https://openalex.org/W2082296643","https://openalex.org/W2082578015","https://openalex.org/W2082677148","https://openalex.org/W2083999930","https://openalex.org/W2085280471","https://openalex.org/W2085831434","https://openalex.org/W2086514756","https://openalex.org/W2087721125","https://openalex.org/W2087796183","https://openalex.org/W2089525117","https://openalex.org/W2090100338","https://openalex.org/W2090562220","https://openalex.org/W2090883656","https://openalex.org/W2091298400","https://openalex.org/W2092156139","https://openalex.org/W2093165790","https://openalex.org/W2093895190","https://openalex.org/W2094791861","https://openalex.org/W2094800427","https://openalex.org/W2095289107","https://openalex.org/W2095935778","https://openalex.org/W2098654565","https://openalex.org/W2099285233","https://openalex.org/W2099606884","https://openalex.org/W2099679304","https://openalex.org/W2100994995","https://openalex.org/W2101752831","https://openalex.org/W2102308673","https://openalex.org/W2102826200","https://openalex.org/W2103765130","https://openalex.org/W2105057096","https://openalex.org/W2106150379","https://openalex.org/W2106298197","https://openalex.org/W2106749830","https://openalex.org/W2106782312","https://openalex.org/W2106894836","https://openalex.org/W2107985093","https://openalex.org/W2110666890","https://openalex.org/W2112626453","https://openalex.org/W2113123985","https://openalex.org/W2113894819","https://openalex.org/W2114118213","https://openalex.org/W2114302992","https://openalex.org/W2114684608","https://openalex.org/W2115380097","https://openalex.org/W2116947669","https://openalex.org/W2118742829","https://openalex.org/W2122743263","https://openalex.org/W2122883560","https://openalex.org/W2125504755","https://openalex.org/W2125987139","https://openalex.org/W2126424577","https://openalex.org/W2126765952","https://openalex.org/W2128603683","https://openalex.org/W2129573593","https://openalex.org/W2130606072","https://openalex.org/W2131205613","https://openalex.org/W2131411124","https://openalex.org/W2131630404","https://openalex.org/W2132551021","https://openalex.org/W2132610511","https://openalex.org/W2133910053","https://openalex.org/W2137198352","https://openalex.org/W2140350993","https://openalex.org/W2140885226","https://openalex.org/W2141219094","https://openalex.org/W2141362699","https://openalex.org/W2142046859","https://openalex.org/W2142162781","https://openalex.org/W2142801671","https://openalex.org/W2143695056","https://openalex.org/W2145649722","https://openalex.org/W2146253179","https://openalex.org/W2146992068","https://openalex.org/W2147143026","https://openalex.org/W2147153041","https://openalex.org/W2149341739","https://openalex.org/W2150042837","https://openalex.org/W2150058708","https://openalex.org/W2151776485","https://openalex.org/W2152851858","https://openalex.org/W2153949260","https://openalex.org/W2155748521","https://openalex.org/W2157010935","https://openalex.org/W2158961840","https://openalex.org/W2159387246","https://openalex.org/W2159468893","https://openalex.org/W2159542600","https://openalex.org/W2162426041","https://openalex.org/W2164223789","https://openalex.org/W2167010128","https://openalex.org/W2168967248","https://openalex.org/W2168994101","https://openalex.org/W2169275072","https://openalex.org/W2172164714","https://openalex.org/W2173410376","https://openalex.org/W2184277544","https://openalex.org/W2190221908","https://openalex.org/W2206726567","https://openalex.org/W2234995241","https://openalex.org/W2238974852","https://openalex.org/W2259823352","https://openalex.org/W2261256504","https://openalex.org/W2268771337","https://openalex.org/W2286771936","https://openalex.org/W2301845707","https://openalex.org/W2321178842","https://openalex.org/W2386180845","https://openalex.org/W2410576463","https://openalex.org/W2414683703","https://openalex.org/W2414701500","https://openalex.org/W2431663241","https://openalex.org/W2464253764","https://openalex.org/W2467992712","https://openalex.org/W2479598273","https://openalex.org/W2484479210","https://openalex.org/W2500442904","https://openalex.org/W2500804873","https://openalex.org/W2502401296","https://openalex.org/W4252175453","https://openalex.org/W4255781844","https://openalex.org/W4292081433","https://openalex.org/W6602732489","https://openalex.org/W6718245233"],"related_works":["https://openalex.org/W4383959330","https://openalex.org/W2886050999","https://openalex.org/W3014664585","https://openalex.org/W3117913230","https://openalex.org/W4210982877","https://openalex.org/W2159468893","https://openalex.org/W4376309456","https://openalex.org/W2580970567","https://openalex.org/W2088640654","https://openalex.org/W2414936143"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":35},{"year":2025,"cited_by_count":51},{"year":2024,"cited_by_count":80},{"year":2023,"cited_by_count":111},{"year":2022,"cited_by_count":86},{"year":2021,"cited_by_count":94},{"year":2020,"cited_by_count":68},{"year":2019,"cited_by_count":66},{"year":2018,"cited_by_count":56},{"year":2017,"cited_by_count":17}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2017-01-26T00:00:00"}
