{"id":"https://openalex.org/W2575214870","doi":"https://doi.org/10.1080/10428194.2016.1272680","title":"MicroRNAs and tRNA-derived fragments predict the transformation of myelodysplastic syndromes to acute myeloid leukemia","display_name":"MicroRNAs and tRNA-derived fragments predict the transformation of myelodysplastic syndromes to acute myeloid leukemia","publication_year":2017,"publication_date":"2017-01-13","ids":{"openalex":"https://openalex.org/W2575214870","doi":"https://doi.org/10.1080/10428194.2016.1272680","mag":"2575214870","pmid":"https://pubmed.ncbi.nlm.nih.gov/28084850","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5505168"},"language":"en","primary_location":{"id":"doi:10.1080/10428194.2016.1272680","doi":"https://doi.org/10.1080/10428194.2016.1272680","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10428194.2016.1272680","pdf_url":null,"source":{"id":"https://openalex.org/S27064115","display_name":"Leukemia & lymphoma/Leukemia and lymphoma","issn_l":"1026-8022","issn":["1026-8022","1029-2403","1042-8194"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Leukemia &amp; Lymphoma","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC5505168","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056796466","display_name":"Yan Ping Guo","orcid":"https://orcid.org/0000-0001-5252-3960","observed_orcids":["https://orcid.org/0000-0001-5252-3960"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yan Guo","raw_affiliation_strings":["Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA;","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032665185","display_name":"Stephen Anthony Strickland","orcid":"https://orcid.org/0000-0002-6861-2041","observed_orcids":["https://orcid.org/0000-0002-6861-2041"]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen A. Strickland","raw_affiliation_strings":["Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN, USA;","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051485142","display_name":"Sanjay Ram Mohan","orcid":"https://orcid.org/0000-0002-6715-6697","observed_orcids":["https://orcid.org/0000-0002-6715-6697"]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sanjay Mohan","raw_affiliation_strings":["Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN, USA;","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101659644","display_name":"Shaoying Li","orcid":"https://orcid.org/0000-0002-6857-0523","observed_orcids":["https://orcid.org/0000-0002-6857-0523","https://orcid.org/0009-0006-4295-0567"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shaoying Li","raw_affiliation_strings":["Hematopathology Department, The University of Texas MD Anderson Cancer Center, Houston, TX, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematopathology Department, The University of Texas MD Anderson Cancer Center, Houston, TX, USA;","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081021825","display_name":"Amma Bosompem","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amma Bosompem","raw_affiliation_strings":["Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA;","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025571380","display_name":"Kasey C. Vickers","orcid":"https://orcid.org/0000-0001-5643-3102","observed_orcids":["https://orcid.org/0000-0001-5643-3102"]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kasey C. Vickers","raw_affiliation_strings":["Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA;","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101974311","display_name":"Shilin Zhao","orcid":"https://orcid.org/0000-0002-3787-8111","observed_orcids":["https://orcid.org/0000-0002-3787-8111"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shilin Zhao","raw_affiliation_strings":["Department of Cancer Biology, Vanderbilt University, Nashville, TN, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology, Vanderbilt University, Nashville, TN, USA;","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040171040","display_name":"Quanhu Sheng","orcid":"https://orcid.org/0000-0001-8951-9295","observed_orcids":["https://orcid.org/0000-0001-8951-9295"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Quanhu Sheng","raw_affiliation_strings":["Department of Cancer Biology, Vanderbilt University, Nashville, TN, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology, Vanderbilt University, Nashville, TN, USA;","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026268460","display_name":"Annette S. Kim","orcid":"https://orcid.org/0000-0002-8699-2439","observed_orcids":["https://orcid.org/0000-0002-8699-2439"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Annette S. Kim","raw_affiliation_strings":["Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-8699-2439","affiliations":[{"raw_affiliation_string":"Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1283280774"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5026268460"],"corresponding_institution_ids":["https://openalex.org/I1283280774"],"apc_list":null,"apc_paid":null,"fwci":7.9817,"has_fulltext":false,"cited_by_count":69,"citation_normalized_percentile":{"value":0.98074826,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":92,"max":100},"biblio":{"volume":"58","issue":"9","first_page":"2144","last_page":"2155"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.015200000256299973,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myelodysplastic-syndrome","display_name":"myelodysplastic syndrome","score":0.9909999966621399},{"id":"https://openalex.org/keywords/acute-myeloid-leukemia","display_name":"acute myeloid leukemia","score":0.9909999966621399},{"id":"https://openalex.org/keywords/disease-progression","display_name":"disease progression","score":0.7570000290870667},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.8989999890327454},{"id":"https://openalex.org/keywords/trna-derived-fragments","display_name":"tRNA-derived fragments","score":0.9279999732971191},{"id":"https://openalex.org/keywords/small-rna","display_name":"small RNA","score":0.8489999771118164},{"id":"https://openalex.org/keywords/mirna-isoforms","display_name":"miRNA isoforms","score":0.843999981880188},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.7289999723434448},{"id":"https://openalex.org/keywords/clonal-hematopoiesis","display_name":"clonal hematopoiesis","score":0.8209999799728394}],"concepts":[{"id":"https://openalex.org/C2780817109","wikidata":"https://www.wikidata.org/wiki/Q954625","display_name":"Myelodysplastic syndromes","level":3,"score":0.8879793882369995},{"id":"https://openalex.org/C2778729363","wikidata":"https://www.wikidata.org/wiki/Q11688946","display_name":"Myeloid leukemia","level":2,"score":0.7495936155319214},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.7360800504684448},{"id":"https://openalex.org/C2779282312","wikidata":"https://www.wikidata.org/wiki/Q1956561","display_name":"Myeloid","level":2,"score":0.5513021945953369},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.5287011861801147},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.4809081554412842},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4665279984474182},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.44374188780784607},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4303325116634369},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4217257797718048},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3863731324672699},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3500283658504486},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.34771662950515747},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.33831387758255005},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.290524423122406},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.26377880573272705},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.19663000106811523}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009190","descriptor_name":"Myelodysplastic Syndromes","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009190","descriptor_name":"Myelodysplastic Syndromes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009190","descriptor_name":"Myelodysplastic Syndromes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012343","descriptor_name":"RNA, Transfer","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015470","descriptor_name":"Leukemia, Myeloid, Acute","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D015470","descriptor_name":"Leukemia, Myeloid, Acute","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015470","descriptor_name":"Leukemia, Myeloid, Acute","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1080/10428194.2016.1272680","doi":"https://doi.org/10.1080/10428194.2016.1272680","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10428194.2016.1272680","pdf_url":null,"source":{"id":"https://openalex.org/S27064115","display_name":"Leukemia & lymphoma/Leukemia and lymphoma","issn_l":"1026-8022","issn":["1026-8022","1029-2403","1042-8194"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Leukemia &amp; Lymphoma","raw_type":"journal-article"},{"id":"pmid:28084850","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28084850","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Leukemia & lymphoma","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5066002","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5505168","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5505168","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5505168","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Leuk Lymphoma","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5066002","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5505168","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1496954631","display_name":"Circulating microRNAs Control Cholesterol Homeostasis through hepatic mechanisms","funder_award_id":"K22HL113039","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6412375718","display_name":"HDL-microRNA Intercellular Communication in Atherosclerosis","funder_award_id":"R01HL128996","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6628171993","display_name":"The Vanderbilt Institute for Clinical and Translational Research (VICTR) UL1","funder_award_id":"UL1RR024975","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G7498365172","display_name":"Macrophage SR-BI Regulates Autophagy, Angiogenin and tRNA-derived small RNAs","funder_award_id":"R01HL127173","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000880732","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA068485","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000905582","display_name":"HDL Function in Human Disease","funder_award_id":"P01HL116263","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320307856","display_name":"World Health Organization","ror":"https://ror.org/01f80g185"},{"id":"https://openalex.org/F4320309151","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34"},{"id":"https://openalex.org/F4320316438","display_name":"Georgia Clinical and Translational Science Alliance","ror":"https://ror.org/034hw7m59"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":75,"referenced_works":["https://openalex.org/W150563020","https://openalex.org/W187238933","https://openalex.org/W205262919","https://openalex.org/W754452945","https://openalex.org/W1551919060","https://openalex.org/W1605230984","https://openalex.org/W1832399013","https://openalex.org/W1849737288","https://openalex.org/W1916500361","https://openalex.org/W1964532149","https://openalex.org/W1969628021","https://openalex.org/W1970373031","https://openalex.org/W1974087139","https://openalex.org/W1974249701","https://openalex.org/W1974300980","https://openalex.org/W1975258982","https://openalex.org/W1979144446","https://openalex.org/W1994039406","https://openalex.org/W1996545149","https://openalex.org/W2000543053","https://openalex.org/W2011715510","https://openalex.org/W2020966397","https://openalex.org/W2021967782","https://openalex.org/W2025826318","https://openalex.org/W2026134786","https://openalex.org/W2026745206","https://openalex.org/W2028951287","https://openalex.org/W2036649644","https://openalex.org/W2036897871","https://openalex.org/W2041241597","https://openalex.org/W2053447157","https://openalex.org/W2055309264","https://openalex.org/W2056115325","https://openalex.org/W2056208804","https://openalex.org/W2061638986","https://openalex.org/W2068332602","https://openalex.org/W2070196854","https://openalex.org/W2070494208","https://openalex.org/W2077327925","https://openalex.org/W2077830421","https://openalex.org/W2081113032","https://openalex.org/W2087463572","https://openalex.org/W2097400599","https://openalex.org/W2099660828","https://openalex.org/W2107027906","https://openalex.org/W2110065044","https://openalex.org/W2112453062","https://openalex.org/W2114942826","https://openalex.org/W2120456037","https://openalex.org/W2121761021","https://openalex.org/W2123355582","https://openalex.org/W2123680400","https://openalex.org/W2124985265","https://openalex.org/W2125720510","https://openalex.org/W2127738065","https://openalex.org/W2141384633","https://openalex.org/W2142574304","https://openalex.org/W2144770839","https://openalex.org/W2149313870","https://openalex.org/W2157326360","https://openalex.org/W2163199119","https://openalex.org/W2179438025","https://openalex.org/W2215639959","https://openalex.org/W2252865825","https://openalex.org/W2258643423","https://openalex.org/W2270590066","https://openalex.org/W2303912045","https://openalex.org/W2307595788","https://openalex.org/W2326726820","https://openalex.org/W2339658711","https://openalex.org/W2510630609","https://openalex.org/W2516121919","https://openalex.org/W2979326436","https://openalex.org/W4210767115","https://openalex.org/W7073834223"],"related_works":["https://openalex.org/W2581293588","https://openalex.org/W3032822804","https://openalex.org/W3089094475","https://openalex.org/W4417503322","https://openalex.org/W2045344595","https://openalex.org/W2053447157","https://openalex.org/W4400577457","https://openalex.org/W7135939925","https://openalex.org/W4403213055","https://openalex.org/W3158798650"],"abstract_inverted_index":{"Myelodysplastic":[0],"syndromes":[1],"(MDS)":[2],"are":[3,142],"clonal":[4],"hematopoietic":[5],"disorders":[6],"of":[7,15,33,48,59,95,108,116,125],"the":[8,46,117],"elderly":[9],"that":[10,38,101,137,141],"carry":[11],"an":[12,78],"increased":[13],"risk":[14],"progression":[16,47],"to":[17,40,50,68,77,144,146],"acute":[18],"myeloid":[19],"leukemia":[20],"(AML).":[21],"Since":[22],"small":[23],"non-coding":[24],"RNAs":[25],"(sRNAs),":[26],"including":[27,88,113],"microRNA":[28],"(miRNAs),":[29],"act":[30],"as":[31,120,122],"regulators":[32],"cellular":[34],"differentiation,":[35],"we":[36,132],"hypothesized":[37],"changes":[39],"sRNAs":[41],"might":[42],"be":[43],"implicated":[44],"in":[45],"MDS":[49,139],"AML.":[51,147],"We":[52,97],"conducted":[53],"sRNA":[54,135],"sequencing":[55],"on":[56],"three":[57,114],"sets":[58],"patients:":[60],"Group":[61,70,81],"A":[62,104],"(MDS":[63,72],"patients":[64,73,84,89],"who":[65,74],"never":[66],"progressed":[67,76],"AML);":[69,79],"B":[71],"later":[75],"and":[80,105,129],"C":[82],"(AML":[83],"with":[85,90],"myelodysplasia-related":[86],"changes,":[87],"a":[91],"known":[92],"preceding":[93],"diagnosis":[94],"MDS).":[96],"identified":[98,134],"five":[99],"miRNAs":[100],"differentiated":[102],"Groups":[103],"B,":[106],"independent":[107],"bone":[109],"marrow":[110],"blast":[111],"percentage,":[112],"members":[115],"miR-181":[118],"family,":[119],"well":[121],"differential":[123],"patterns":[124],"miRNA":[126],"isoforms":[127],"(isomiRs)":[128],"tDRs.":[130],"Thus,":[131],"have":[133],"biomarkers":[136],"predict":[138],"cases":[140],"likely":[143],"progress":[145]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":19},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-01-26T00:00:00"}
