{"id":"https://openalex.org/W2575177621","doi":null,"title":"\"Glutamate Excitotoxicity: An Insight into the Mechanism\".","display_name":"\"Glutamate Excitotoxicity: An Insight into the Mechanism\".","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2575177621","mag":"2575177621"},"language":"en","primary_location":{"id":"mag:2575177621","doi":null,"is_oa":false,"landing_page_url":"https://www.researchgate.net/profile/Ehtishamul_Haq/publication/264424639_Glutamate_Excitotoxicity_An_Insight_into_the_Mechanism/links/53df06a70cf2a76fb6680460.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081000126","display_name":"Henah Mehraj Balkhi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Henah Mehraj Balkhi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069464766","display_name":"Taseen Gul","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Taseen Gul","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055384980","display_name":"Mujeeb Zafar Banday","orcid":"https://orcid.org/0000-0001-8738-4614","observed_orcids":["https://orcid.org/0000-0001-8738-4614"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mujeeb Zafar Banday","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8738-4614","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5032384338","display_name":"Ehtishamul Haq","orcid":"https://orcid.org/0000-0002-4195-0606","observed_orcids":["https://orcid.org/0000-0002-4195-0606"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ehtishamul Haq","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4195-0606","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2447,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.50390384,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glutamate-excitotoxicity","display_name":"glutamate excitotoxicity","score":0.9679999947547913},{"id":"https://openalex.org/keywords/glutamate-receptors","display_name":"glutamate receptors","score":0.9679999947547913},{"id":"https://openalex.org/keywords/excitotoxic-cell-death","display_name":"excitotoxic cell death","score":0.8050000071525574},{"id":"https://openalex.org/keywords/glutamatergic-neurotransmission","display_name":"glutamatergic neurotransmission","score":0.6800000071525574},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.7870000004768372},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.5989999771118164},{"id":"https://openalex.org/keywords/glutamate-metabolism","display_name":"glutamate metabolism","score":0.625}],"concepts":[{"id":"https://openalex.org/C2781012912","wikidata":"https://www.wikidata.org/wiki/Q901117","display_name":"Excitotoxicity","level":4,"score":0.9895217418670654},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.8486734628677368},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7379392385482788},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.5946142673492432},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3741980195045471},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35547658801078796},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.28148990869522095},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13949120044708252},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.09414184093475342},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.05335921049118042}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2575177621","doi":null,"is_oa":false,"landing_page_url":"https://www.researchgate.net/profile/Ehtishamul_Haq/publication/264424639_Glutamate_Excitotoxicity_An_Insight_into_the_Mechanism/links/53df06a70cf2a76fb6680460.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.46810001134872437,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":96,"referenced_works":["https://openalex.org/W946801353","https://openalex.org/W1269597682","https://openalex.org/W1484355820","https://openalex.org/W1500094754","https://openalex.org/W1552073493","https://openalex.org/W1562792231","https://openalex.org/W1574540499","https://openalex.org/W1576577565","https://openalex.org/W1582272079","https://openalex.org/W1601332829","https://openalex.org/W1603471307","https://openalex.org/W1608350875","https://openalex.org/W1662302126","https://openalex.org/W1721669572","https://openalex.org/W1817392531","https://openalex.org/W1867012516","https://openalex.org/W1956388268","https://openalex.org/W1957783567","https://openalex.org/W1958675123","https://openalex.org/W1964553929","https://openalex.org/W1965438300","https://openalex.org/W1966594035","https://openalex.org/W1966761076","https://openalex.org/W1967476518","https://openalex.org/W1971502696","https://openalex.org/W1973249583","https://openalex.org/W1973252641","https://openalex.org/W1976955003","https://openalex.org/W1978266024","https://openalex.org/W1981028990","https://openalex.org/W1985584861","https://openalex.org/W1987080089","https://openalex.org/W1988726352","https://openalex.org/W1993385893","https://openalex.org/W1994127068","https://openalex.org/W2000080307","https://openalex.org/W2000761533","https://openalex.org/W2003410399","https://openalex.org/W2005003771","https://openalex.org/W2006806309","https://openalex.org/W2010848099","https://openalex.org/W2013986174","https://openalex.org/W2015412484","https://openalex.org/W2015747402","https://openalex.org/W2016413308","https://openalex.org/W2019859522","https://openalex.org/W2020160421","https://openalex.org/W2020931266","https://openalex.org/W2021029707","https://openalex.org/W2024945446","https://openalex.org/W2029918421","https://openalex.org/W2030214963","https://openalex.org/W2032444047","https://openalex.org/W2033678540","https://openalex.org/W2036839645","https://openalex.org/W2042651745","https://openalex.org/W2042717034","https://openalex.org/W2043166209","https://openalex.org/W2045281710","https://openalex.org/W2049511526","https://openalex.org/W2051395367","https://openalex.org/W2052503745","https://openalex.org/W2053739364","https://openalex.org/W2054307806","https://openalex.org/W2054566340","https://openalex.org/W2059785678","https://openalex.org/W2061265791","https://openalex.org/W2062341643","https://openalex.org/W2079352525","https://openalex.org/W2085402579","https://openalex.org/W2087141223","https://openalex.org/W2094027072","https://openalex.org/W2094673798","https://openalex.org/W2095025678","https://openalex.org/W2095521912","https://openalex.org/W2100569416","https://openalex.org/W2107893282","https://openalex.org/W2109078104","https://openalex.org/W2110653553","https://openalex.org/W2120307371","https://openalex.org/W2123615043","https://openalex.org/W2124729399","https://openalex.org/W2131024077","https://openalex.org/W2131437696","https://openalex.org/W2132949150","https://openalex.org/W2136424515","https://openalex.org/W2138861499","https://openalex.org/W2154239194","https://openalex.org/W2155551742","https://openalex.org/W2159650080","https://openalex.org/W2160648225","https://openalex.org/W2160954023","https://openalex.org/W2167000365","https://openalex.org/W2400014979","https://openalex.org/W2412841281","https://openalex.org/W3149346444"],"related_works":["https://openalex.org/W2082879602","https://openalex.org/W151767562","https://openalex.org/W4282837361","https://openalex.org/W145122870","https://openalex.org/W2049729089","https://openalex.org/W2029994068","https://openalex.org/W2530472223","https://openalex.org/W2926695396","https://openalex.org/W131379985","https://openalex.org/W2914736643"],"abstract_inverted_index":{"Blatant":[0],"role":[1],"of":[2,20,35,48,65,84,107],"glutamate":[3,23,66,73,85],"in":[4,27,33,71],"physiology":[5,83],"and":[6,17,51,59,82,87,90,111,121],"neurologic":[7],"disorders":[8],"has":[9],"made":[10],"it":[11,30],"challenging":[12],"to":[13,56,77,113],"know":[14],"its":[15],"chemistry":[16],"metabolic":[18],"mode":[19],"action.":[21],"As":[22],"is":[24,31,47],"ubiquitously":[25],"present":[26],"the":[28,44,80,105,108],"brain,":[29],"involved":[32],"number":[34],"essential":[36],"phenomenons":[37],"associated":[38],"with":[39,99],"neural":[40,75],"functioning.":[41],"Among":[42],"all":[43],"processes":[45,110],"excitotoxicity":[46,54,120,125],"great":[49],"significance":[50],"consequence.":[52],"Glutamate":[53],"refers":[55],"neuronal":[57],"dysfunction":[58],"degeneration":[60],"caused":[61],"by":[62],"over":[63],"activation":[64],"receptors.":[67],"This":[68],"overview":[69],"apostrophizes":[70],"brief":[72],"from":[74],"transmission":[76],"excitotoxicity,":[78],"engrossing":[79],"structure":[81],"receptors":[86],"plausible":[88],"cellular":[89],"molecular":[91],"mechanisms":[92],"underlying":[93],"excitotoxic":[94],"cell":[95],"death.":[96],"Considerable":[97],"acquaintance":[98],"this":[100],"intriguing":[101],"phenomenon":[102],"will":[103],"enhance":[104],"understanding":[106],"neuropathologic":[109],"help":[112],"develop":[114],"a":[115],"conceptual":[116],"model":[117],"for":[118,124],"modulating":[119],"emerging":[122],"targets":[123],"research.":[126],".":[127]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2017-01-26T00:00:00"}