{"id":"https://openalex.org/W2574436631","doi":"https://doi.org/10.1097/ogx.0000000000000403","title":"Noninvasive Prenatal Screening for Fetal Aneuploidy, 2016 Update: A Position Statement of the American College of Medical Genetics and Genomics","display_name":"Noninvasive Prenatal Screening for Fetal Aneuploidy, 2016 Update: A Position Statement of the American College of Medical Genetics and Genomics","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2574436631","doi":"https://doi.org/10.1097/ogx.0000000000000403","mag":"2574436631"},"language":"en","primary_location":{"id":"doi:10.1097/ogx.0000000000000403","doi":"https://doi.org/10.1097/ogx.0000000000000403","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ogx.0000000000000403","pdf_url":null,"source":{"id":"https://openalex.org/S115789314","display_name":"Obstetrical & Gynecological Survey","issn_l":"0029-7828","issn":["0029-7828","1533-9866"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrical & Gynecological Survey","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103068001","display_name":"Anthony R. Gregg","orcid":"https://orcid.org/0000-0002-7225-040X","observed_orcids":["https://orcid.org/0000-0002-7225-040X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anthony R. Gregg","raw_affiliation_strings":["(A.R.G)","(B.G.S)","(K.B.)","(R.G.B.)","(S.K.)","M.S.W)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(A.R.G)","institution_ids":[]},{"raw_affiliation_string":"(B.G.S)","institution_ids":[]},{"raw_affiliation_string":"(K.B.)","institution_ids":[]},{"raw_affiliation_string":"(R.G.B.)","institution_ids":[]},{"raw_affiliation_string":"(S.K.)","institution_ids":[]},{"raw_affiliation_string":"M.S.W)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087067193","display_name":"Brian G. Skotko","orcid":"https://orcid.org/0000-0002-5232-9882","observed_orcids":["https://orcid.org/0000-0002-5232-9882"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brian G. Skotko","raw_affiliation_strings":["(A.R.G)","(B.G.S)","(K.B.)","(R.G.B.)","(S.K.)","M.S.W)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(A.R.G)","institution_ids":[]},{"raw_affiliation_string":"(B.G.S)","institution_ids":[]},{"raw_affiliation_string":"(K.B.)","institution_ids":[]},{"raw_affiliation_string":"(R.G.B.)","institution_ids":[]},{"raw_affiliation_string":"(S.K.)","institution_ids":[]},{"raw_affiliation_string":"M.S.W)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000406381","display_name":"Judith Benkendorf","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Judith L. Benkendorf","raw_affiliation_strings":["(A.R.G)","(B.G.S)","(K.B.)","(R.G.B.)","(S.K.)","M.S.W)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(A.R.G)","institution_ids":[]},{"raw_affiliation_string":"(B.G.S)","institution_ids":[]},{"raw_affiliation_string":"(K.B.)","institution_ids":[]},{"raw_affiliation_string":"(R.G.B.)","institution_ids":[]},{"raw_affiliation_string":"(S.K.)","institution_ids":[]},{"raw_affiliation_string":"M.S.W)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003679316","display_name":"Kristin G. Monaghan","orcid":"https://orcid.org/0000-0003-3406-1250","observed_orcids":["https://orcid.org/0000-0003-3406-1250","https://orcid.org/0000-0003-4928-1475","https://orcid.org/0000-0002-2185-0691"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kristin G. Monaghan","raw_affiliation_strings":["(A.R.G)","(B.G.S)","(K.B.)","(R.G.B.)","(S.K.)","M.S.W)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(A.R.G)","institution_ids":[]},{"raw_affiliation_string":"(B.G.S)","institution_ids":[]},{"raw_affiliation_string":"(K.B.)","institution_ids":[]},{"raw_affiliation_string":"(R.G.B.)","institution_ids":[]},{"raw_affiliation_string":"(S.K.)","institution_ids":[]},{"raw_affiliation_string":"M.S.W)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038687912","display_name":"Komal Bajaj","orcid":"https://orcid.org/0000-0002-0942-3021","observed_orcids":["https://orcid.org/0000-0002-0942-3021"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Komal Bajaj","raw_affiliation_strings":["(A.R.G)","(B.G.S)","(K.B.)","(R.G.B.)","(S.K.)","M.S.W)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(A.R.G)","institution_ids":[]},{"raw_affiliation_string":"(B.G.S)","institution_ids":[]},{"raw_affiliation_string":"(K.B.)","institution_ids":[]},{"raw_affiliation_string":"(R.G.B.)","institution_ids":[]},{"raw_affiliation_string":"(S.K.)","institution_ids":[]},{"raw_affiliation_string":"M.S.W)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001165231","display_name":"Robert G. Best","orcid":"https://orcid.org/0000-0002-9691-125X","observed_orcids":["https://orcid.org/0000-0002-9691-125X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert G. Best","raw_affiliation_strings":["(A.R.G)","(B.G.S)","(K.B.)","(R.G.B.)","(S.K.)","M.S.W)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(A.R.G)","institution_ids":[]},{"raw_affiliation_string":"(B.G.S)","institution_ids":[]},{"raw_affiliation_string":"(K.B.)","institution_ids":[]},{"raw_affiliation_string":"(R.G.B.)","institution_ids":[]},{"raw_affiliation_string":"(S.K.)","institution_ids":[]},{"raw_affiliation_string":"M.S.W)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052153200","display_name":"Susan D. Klugman","orcid":"https://orcid.org/0000-0001-8775-008X","observed_orcids":["https://orcid.org/0000-0001-8775-008X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Susan Klugman","raw_affiliation_strings":["(A.R.G)","(B.G.S)","(K.B.)","(R.G.B.)","(S.K.)","M.S.W)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(A.R.G)","institution_ids":[]},{"raw_affiliation_string":"(B.G.S)","institution_ids":[]},{"raw_affiliation_string":"(K.B.)","institution_ids":[]},{"raw_affiliation_string":"(R.G.B.)","institution_ids":[]},{"raw_affiliation_string":"(S.K.)","institution_ids":[]},{"raw_affiliation_string":"M.S.W)","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110018455","display_name":"Michael S. Watson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael S. Watson","raw_affiliation_strings":["(A.R.G)","(B.G.S)","(K.B.)","(R.G.B.)","(S.K.)","M.S.W)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(A.R.G)","institution_ids":[]},{"raw_affiliation_string":"(B.G.S)","institution_ids":[]},{"raw_affiliation_string":"(K.B.)","institution_ids":[]},{"raw_affiliation_string":"(R.G.B.)","institution_ids":[]},{"raw_affiliation_string":"(S.K.)","institution_ids":[]},{"raw_affiliation_string":"M.S.W)","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.8925,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.92658207,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"72","issue":"1","first_page":"6","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10453","display_name":"Maternal and Perinatal Health Interventions","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10786","display_name":"Maternal Mental Health During Pregnancy and Postpartum","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/noninvasive-prenatal-screening","display_name":"noninvasive prenatal screening","score":0.9879999756813049},{"id":"https://openalex.org/keywords/fetal-aneuploidy","display_name":"fetal aneuploidy","score":0.9890000224113464},{"id":"https://openalex.org/keywords/cell-free-dna","display_name":"cell-free DNA","score":0.8619999885559082},{"id":"https://openalex.org/keywords/maternal-blood","display_name":"maternal blood","score":0.6620000004768372},{"id":"https://openalex.org/keywords/prenatal-genetic-testing","display_name":"prenatal genetic testing","score":0.6209999918937683},{"id":"https://openalex.org/keywords/clinical-guidelines","display_name":"clinical guidelines","score":0.3799999952316284}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8338286280632019},{"id":"https://openalex.org/C2780182762","wikidata":"https://www.wikidata.org/wiki/Q1630279","display_name":"Guideline","level":2,"score":0.6239402294158936},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.5878583192825317},{"id":"https://openalex.org/C2992422692","wikidata":"https://www.wikidata.org/wiki/Q1136569","display_name":"Prenatal screening","level":5,"score":0.5742056965827942},{"id":"https://openalex.org/C2778258057","wikidata":"https://www.wikidata.org/wiki/Q1136569","display_name":"Prenatal diagnosis","level":4,"score":0.5372884273529053},{"id":"https://openalex.org/C152110520","wikidata":"https://www.wikidata.org/wiki/Q14225730","display_name":"Cell-free fetal DNA","level":5,"score":0.5261663198471069},{"id":"https://openalex.org/C64474127","wikidata":"https://www.wikidata.org/wiki/Q1071953","display_name":"Medical genetics","level":3,"score":0.5258258581161499},{"id":"https://openalex.org/C2775887326","wikidata":"https://www.wikidata.org/wiki/Q3308829","display_name":"Prenatal care","level":3,"score":0.4516821801662445},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.3986254334449768},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.39465653896331787},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.35745319724082947},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.2638453543186188},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.25294244289398193},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.24914848804473877},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.20062267780303955},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15509581565856934},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10683336853981018},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/ogx.0000000000000403","doi":"https://doi.org/10.1097/ogx.0000000000000403","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ogx.0000000000000403","pdf_url":null,"source":{"id":"https://openalex.org/S115789314","display_name":"Obstetrical & Gynecological Survey","issn_l":"0029-7828","issn":["0029-7828","1533-9866"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrical & Gynecological Survey","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.979200005531311,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.47999998927116394,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3017025014","https://openalex.org/W7039906999","https://openalex.org/W4382199509","https://openalex.org/W3024682669","https://openalex.org/W2600723055","https://openalex.org/W4324117223","https://openalex.org/W2968900619","https://openalex.org/W2121854446","https://openalex.org/W4321503383","https://openalex.org/W2906457582"],"abstract_inverted_index":{"(Abstracted":[0],"from":[1,27],"Genet":[2],"Med":[3],"2016;18(10):1056\u20131065)":[4],"Rapid":[5],"advancements":[6],"in":[7,14,32,40,56],"genomic":[8],"technologies":[9],"led":[10],"to":[11,51,75],"the":[12,28],"introduction":[13],"2011":[15],"of":[16,44,58],"noninvasive":[17],"prenatal":[18,36,59],"screening":[19,37,60],"(NIPS)":[20],"that":[21],"used":[22],"cell-free":[23],"DNA":[24],"(cfDNA)":[25],"derived":[26],"placenta":[29],"and":[30,47,62,72],"circulating":[31],"maternal":[33],"blood.":[34],"Noninvasive":[35],"is":[38],"addressed":[39],"this":[41],"American":[42],"College":[43],"Medical":[45],"Genetics":[46],"Genomics":[48],"(ACMG)":[49],"guideline":[50],"assist":[52],"patients":[53],"who":[54,66],"are":[55,67],"search":[57],"information":[61,74],"health":[63],"care":[64],"providers":[65],"responsible":[68],"for":[69],"providing":[70],"precise":[71],"up-to-date":[73],"their":[76],"patients.":[77]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":2}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2017-01-26T00:00:00"}