{"id":"https://openalex.org/W2571238041","doi":"https://doi.org/10.1111/ajt.14194","title":"Disruption of Transplant Tolerance by an \u201cIncognito\u201d Form of CD8 T Cell\u2013Dependent Memory","display_name":"Disruption of Transplant Tolerance by an \u201cIncognito\u201d Form of CD8 T Cell\u2013Dependent Memory","publication_year":2017,"publication_date":"2017-01-09","ids":{"openalex":"https://openalex.org/W2571238041","doi":"https://doi.org/10.1111/ajt.14194","mag":"2571238041","pmid":"https://pubmed.ncbi.nlm.nih.gov/28066981","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5489385"},"language":"en","primary_location":{"id":"doi:10.1111/ajt.14194","doi":"https://doi.org/10.1111/ajt.14194","is_oa":true,"landing_page_url":"https://doi.org/10.1111/ajt.14194","pdf_url":null,"source":{"id":"https://openalex.org/S182625382","display_name":"American Journal of Transplantation","issn_l":"1600-6135","issn":["1600-6135","1600-6143"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1111/ajt.14194","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062239235","display_name":"Michelle K. Nelsen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M.K. Nelsen","raw_affiliation_strings":["Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037436028","display_name":"K. Scott Beard","orcid":"https://orcid.org/0000-0002-6077-4417","observed_orcids":["https://orcid.org/0000-0002-6077-4417"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K.S. Beard","raw_affiliation_strings":["Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036254159","display_name":"Robert J. Plenter","orcid":"https://orcid.org/0000-0002-3036-6092","observed_orcids":["https://orcid.org/0000-0002-3036-6092"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R.J. Plenter","raw_affiliation_strings":["Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066347052","display_name":"Ross M. Kedl","orcid":"https://orcid.org/0000-0002-9065-7895","observed_orcids":["https://orcid.org/0000-0002-9065-7895"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R.M. Kedl","raw_affiliation_strings":["Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014699103","display_name":"Eric T. Clambey","orcid":"https://orcid.org/0000-0002-7972-9544","observed_orcids":["https://orcid.org/0000-0002-7972-9544"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E.T. Clambey","raw_affiliation_strings":["Department of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, CO","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018120698","display_name":"Ronald G. Gill","orcid":"https://orcid.org/0000-0001-7520-4401","observed_orcids":["https://orcid.org/0000-0001-7520-4401"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"R.G. Gill","raw_affiliation_strings":["Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO","institution_ids":["https://openalex.org/I51713134"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5018120698"],"corresponding_institution_ids":["https://openalex.org/I51713134"],"apc_list":{"value":4300,"currency":"USD","value_usd":4300},"apc_paid":{"value":4300,"currency":"USD","value_usd":4300},"fwci":0.6187,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.63191135,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"17","issue":"7","first_page":"1742","last_page":"1753"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.0340999998152256,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12900","display_name":"Organ and Tissue Transplantation Research","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allograft-tolerance","display_name":"allograft tolerance","score":0.8640000224113464},{"id":"https://openalex.org/keywords/transplantation-tolerance","display_name":"transplantation tolerance","score":0.6949999928474426},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.8309999704360962},{"id":"https://openalex.org/keywords/immunological-memory","display_name":"immunological memory","score":0.7059999704360962},{"id":"https://openalex.org/keywords/ovalbumin","display_name":"ovalbumin","score":0.7450000047683716},{"id":"https://openalex.org/keywords/autoantigens","display_name":"autoantigens","score":0.9750000238418579},{"id":"https://openalex.org/keywords/alloantigen","display_name":"alloantigen","score":0.8009999990463257},{"id":"https://openalex.org/keywords/preexisting-immunity","display_name":"pre-existing immunity","score":0.5099999904632568}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7931205034255981},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.5206310153007507},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.4432753920555115},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3640539348125458},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.19649803638458252},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.154484361410141},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08559006452560425},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007156","descriptor_name":"Immunologic Memory","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010047","descriptor_name":"Ovalbumin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D014184","descriptor_name":"Transplantation, Homologous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016381","descriptor_name":"Islets of Langerhans Transplantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017951","descriptor_name":"Antigen Presentation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D018414","descriptor_name":"CD8-Positive T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D023001","descriptor_name":"Transplantation Tolerance","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1111/ajt.14194","doi":"https://doi.org/10.1111/ajt.14194","is_oa":true,"landing_page_url":"https://doi.org/10.1111/ajt.14194","pdf_url":null,"source":{"id":"https://openalex.org/S182625382","display_name":"American Journal of Transplantation","issn_l":"1600-6135","issn":["1600-6135","1600-6143"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Transplantation","raw_type":"journal-article"},{"id":"pmid:28066981","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28066981","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:4973731","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5489385","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5489385","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5489385","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Am J Transplant","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1111/ajt.14194","doi":"https://doi.org/10.1111/ajt.14194","is_oa":true,"landing_page_url":"https://doi.org/10.1111/ajt.14194","pdf_url":null,"source":{"id":"https://openalex.org/S182625382","display_name":"American Journal of Transplantation","issn_l":"1600-6135","issn":["1600-6135","1600-6143"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Transplantation","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3488383117","display_name":null,"funder_award_id":"HHSN-272201300006C","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G4294805107","display_name":"Colorado Clinical and Translational Sciences Institute","funder_award_id":"TL1TR001081","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5627044594","display_name":"Islet transplantation in autoimmune diabetes","funder_award_id":"R01DK099187","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000890470","display_name":"Training Program in Immunology","funder_award_id":"T32AI007405","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W1523683863","https://openalex.org/W1530240148","https://openalex.org/W1532778742","https://openalex.org/W1545698425","https://openalex.org/W1552791058","https://openalex.org/W1586476801","https://openalex.org/W1589207430","https://openalex.org/W1595539869","https://openalex.org/W1606573708","https://openalex.org/W1622954330","https://openalex.org/W1749521422","https://openalex.org/W1895002782","https://openalex.org/W1903027828","https://openalex.org/W1943179159","https://openalex.org/W1968878349","https://openalex.org/W1970072226","https://openalex.org/W1981084653","https://openalex.org/W1992915380","https://openalex.org/W1994026561","https://openalex.org/W1997508510","https://openalex.org/W2003041213","https://openalex.org/W2009661102","https://openalex.org/W2016184595","https://openalex.org/W2020850832","https://openalex.org/W2023147743","https://openalex.org/W2025881173","https://openalex.org/W2026898846","https://openalex.org/W2038208647","https://openalex.org/W2048454985","https://openalex.org/W2050301366","https://openalex.org/W2053432732","https://openalex.org/W2060963592","https://openalex.org/W2065828486","https://openalex.org/W2068238618","https://openalex.org/W2076125315","https://openalex.org/W2083380291","https://openalex.org/W2084407937","https://openalex.org/W2085241267","https://openalex.org/W2089327657","https://openalex.org/W2094134441","https://openalex.org/W2099468505","https://openalex.org/W2100645145","https://openalex.org/W2116127682","https://openalex.org/W2116276243","https://openalex.org/W2117737461","https://openalex.org/W2123737617","https://openalex.org/W2125758525","https://openalex.org/W2126845096","https://openalex.org/W2128963820","https://openalex.org/W2131124022","https://openalex.org/W2131811425","https://openalex.org/W2148052826","https://openalex.org/W2149142511","https://openalex.org/W2152561959","https://openalex.org/W2158307912","https://openalex.org/W2166148915","https://openalex.org/W2167194408","https://openalex.org/W2167745011","https://openalex.org/W2168080774","https://openalex.org/W2378712848","https://openalex.org/W4313343356","https://openalex.org/W4313422306"],"related_works":["https://openalex.org/W2774132137","https://openalex.org/W3092597382","https://openalex.org/W2059023962","https://openalex.org/W2149142511","https://openalex.org/W1982954850","https://openalex.org/W2102812484","https://openalex.org/W2323101903","https://openalex.org/W2076771134","https://openalex.org/W2153537610","https://openalex.org/W2003131745"],"abstract_inverted_index":{"Several":[0],"approaches":[1],"successfully":[2],"achieve":[3],"allograft":[4,23],"tolerance":[5,24,45,75,139,152,187],"in":[6],"preclinical":[7],"models":[8],"but":[9],"are":[10],"challenging":[11],"to":[12,57,69,85,108,119,129,144,185,197],"translate":[13],"into":[14],"clinical":[15,198],"practice.":[16],"Many":[17],"clinically":[18],"relevant":[19],"factors":[20],"can":[21,136,190],"attenuate":[22],"induction,":[25],"including":[26],"intrinsic":[27],"genetic":[28],"resistance,":[29],"peritransplant":[30],"infection,":[31],"inflammation,":[32],"and":[33,72,158,188],"preexisting":[34,62],"antidonor":[35],"immunity.":[36],"The":[37],"prevailing":[38],"view":[39],"for":[40],"immune":[41,92,195],"memory":[42,52,64,93,102],"as":[43,113],"a":[44,82,130],"barrier":[46,196],"is":[47,123,183],"that":[48,54,100,127,182,189],"the":[49,121,166],"host":[50,101,122],"harbors":[51],"cells":[53,65,71,104],"spontaneously":[55],"cross-react":[56],"donor":[58,70,145],"MHC":[59,146],"antigens.":[60,147],"Such":[61],"\"heterologous\"":[63],"have":[66],"direct":[67],"reactivity":[68,143],"resist":[73],"most":[74],"regimens.":[76],"In":[77],"this":[78,149,172],"study,":[79],"we":[80],"developed":[81],"model":[83,131],"system":[84],"determine":[86],"if":[87],"an":[88,175,192],"alternative":[89],"form":[90,179],"of":[91,151,163,180],"could":[94,105],"also":[95],"block":[96],"tolerance.":[97,200],"We":[98],"posited":[99],"T":[103,156],"potentially":[106],"respond":[107],"donor-derived":[109],"non-MHC":[110],"antigens,":[111],"such":[112],"latent":[114],"viral":[115],"antigens":[116],"or":[117,177],"autoantigens,":[118],"which":[120],"immune.":[124],"Results":[125],"show":[126],"immunity":[128,181],"nonself":[132],"antigen,":[133],"ovalbumin":[134],"(OVA),":[135],"dramatically":[137],"disrupt":[138],"despite":[140],"undetectable":[141],"initial":[142],"Importantly,":[148],"blockade":[150],"was":[153],"CD8":[154],"+":[155],"cell\u2013dependent":[157],"required":[159],"linked":[160],"antigen":[161],"presentation":[162],"alloantigens":[164],"with":[165],"test":[167],"OVA":[168],"antigen.":[169],"As":[170],"such,":[171],"pathway":[173],"represents":[174],"unapparent,":[176],"\"incognito,\"":[178],"sufficient":[184],"prevent":[186],"be":[191],"unforeseen":[193],"additional":[194],"transplant":[199]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2017-01-13T00:00:00"}