{"id":"https://openalex.org/W25682316","doi":null,"title":"The significance of plasma high density lipoprotein cholesterol (hdlc).","display_name":"The significance of plasma high density lipoprotein cholesterol (hdlc).","publication_year":2007,"publication_date":"2007-09-01","ids":{"openalex":"https://openalex.org/W25682316","mag":"25682316","pmid":"https://pubmed.ncbi.nlm.nih.gov/18092443"},"language":"en","primary_location":{"id":"pmid:18092443","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18092443","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nepal Medical College journal : NMCJ","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074710772","display_name":"Suprita Gupta","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Suprita Gupta","raw_affiliation_strings":["Department of Biochemistry, National Medical College, Birgunj, Nepal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, National Medical College, Birgunj, Nepal","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083397429","display_name":"Ganapathy Rajagopal","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ganapathy Rajagopal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4464,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.69562222,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"9","issue":"3","first_page":"212","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.5669000148773193,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.5669000148773193,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.42239999771118164,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12975","display_name":"Paraoxonase enzyme and polymorphisms","score":0.006300000008195639,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.9369999766349792},{"id":"https://openalex.org/keywords/cholesterol-transport","display_name":"cholesterol transport","score":0.675000011920929},{"id":"https://openalex.org/keywords/atherogenesis","display_name":"atherogenesis","score":0.7429999709129333},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.9049999713897705},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.9760000109672546},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.7900000214576721},{"id":"https://openalex.org/keywords/exercise","display_name":"physical activity","score":0.6639999747276306},{"id":"https://openalex.org/keywords/lifestyle-modification","display_name":"lifestyle modification","score":0.9419999718666077},{"id":"https://openalex.org/keywords/bile-acid-synthesis","display_name":"bile acid synthesis","score":0.5329999923706055}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7781121730804443},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.7095030546188354},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6155235171318054},{"id":"https://openalex.org/C110459506","wikidata":"https://www.wikidata.org/wiki/Q7318217","display_name":"Reverse cholesterol transport","level":4,"score":0.5916165709495544},{"id":"https://openalex.org/C2780541478","wikidata":"https://www.wikidata.org/wiki/Q410020","display_name":"High-density lipoprotein","level":3,"score":0.5514258146286011},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5317042469978333},{"id":"https://openalex.org/C3018906752","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary heart disease","level":2,"score":0.49916648864746094},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.4264095425605774}],"mesh":[{"descriptor_ui":"D001161","descriptor_name":"Arteriosclerosis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001161","descriptor_name":"Arteriosclerosis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008019","descriptor_name":"Life Style","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008076","descriptor_name":"Cholesterol, HDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016540","descriptor_name":"Smoking Cessation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019161","descriptor_name":"Hydroxymethylglutaryl-CoA Reductase Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:18092443","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18092443","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nepal Medical College journal : NMCJ","raw_type":"Journal Article"},{"id":"mag:25682316","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18092443","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W1552709412","https://openalex.org/W1988442083","https://openalex.org/W1993524316","https://openalex.org/W1995653405","https://openalex.org/W1996234795","https://openalex.org/W2000800064","https://openalex.org/W2003163223","https://openalex.org/W2018178643","https://openalex.org/W2040589021","https://openalex.org/W2043154979","https://openalex.org/W2048993312","https://openalex.org/W2053217945","https://openalex.org/W2063391304","https://openalex.org/W2065028684","https://openalex.org/W2068491694","https://openalex.org/W2068877753","https://openalex.org/W2074899698","https://openalex.org/W2081801534","https://openalex.org/W2084993196","https://openalex.org/W2087911379","https://openalex.org/W2096198395","https://openalex.org/W2100496118","https://openalex.org/W2102583631","https://openalex.org/W2107562400","https://openalex.org/W2110881163","https://openalex.org/W2111662961","https://openalex.org/W2112854176","https://openalex.org/W2113923156","https://openalex.org/W2115092750","https://openalex.org/W2115847479","https://openalex.org/W2116708624","https://openalex.org/W2129360604","https://openalex.org/W2132157071","https://openalex.org/W2132540363","https://openalex.org/W2133741785","https://openalex.org/W2133867160","https://openalex.org/W2138604360","https://openalex.org/W2138851777","https://openalex.org/W2140300598","https://openalex.org/W2146570456","https://openalex.org/W2148783573","https://openalex.org/W2152905269","https://openalex.org/W2160982674","https://openalex.org/W2166084034","https://openalex.org/W2171139285","https://openalex.org/W2244410202","https://openalex.org/W2325748026","https://openalex.org/W2332183914","https://openalex.org/W2337202947","https://openalex.org/W2461360472","https://openalex.org/W2462237620","https://openalex.org/W2500646860","https://openalex.org/W2600898673","https://openalex.org/W2605292800","https://openalex.org/W6772754464"],"related_works":["https://openalex.org/W3351662","https://openalex.org/W2365840962","https://openalex.org/W2026497415","https://openalex.org/W2408988722","https://openalex.org/W1984048743","https://openalex.org/W2077089918","https://openalex.org/W2976217346","https://openalex.org/W2356927191","https://openalex.org/W7095485258","https://openalex.org/W2407451989"],"abstract_inverted_index":{"High":[0],"Density":[1],"Lipoprotein":[2],"(HDL)":[3],"transports":[4],"in":[5,59,78,101],"plasma,":[6],"phospholipids,":[7],"cholesterol,":[8],"and":[9,38,42,71,76,92],"triacylglycerol.":[10],"The":[11,28],"cholesterol":[12,18,32],"associated":[13],"with":[14],"HDL":[15],"(HDLc)":[16],"is":[17,20,49],"that":[19],"scavenged":[21],"from":[22,67],"peripheral":[23],"tissues":[24],"back":[25],"to":[26],"liver.":[27],"liver":[29],"converts":[30],"this":[31],"into":[33,45],"bile":[34,36],"acids,":[35],"salts,":[37],"esterifies":[39],"the":[40,97],"rest":[41],"secretes":[43],"them":[44],"bile.":[46],"Low":[47],"HDLc":[48,58,100],"a":[50],"risk":[51],"factor":[52],"for":[53],"atherogenesis.":[54],"Higher":[55],"levels":[56],"of":[57,65,83,99],"plasma":[60],"are":[61],"therefore":[62],"an":[63],"index":[64],"safety":[66],"coronary":[68],"heart":[69],"disease":[70],"atherosclerosis.":[72],"Regular":[73],"physical":[74],"exercise,":[75],"changes":[77],"life":[79],"style":[80],"like":[81],"cessation":[82],"smoking,":[84],"lowered":[85],"alcohol":[86],"consumption,":[87],"modified":[88],"dietary":[89],"fat":[90],"intake":[91],"certain":[93],"medications":[94],"can":[95],"improve":[96],"level":[98],"plasma.":[102]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}