{"id":"https://openalex.org/W2565726679","doi":null,"title":"EXAMINATION OF THE EFFECTS OF VALPROIC ACID EXPOSURE OR P300 PROTEIN INHIBITION ON THE BALANCE OF APOPTOSIS AND PROLIFERATION IN P19 EMBRYONAL CARCINOMA CELLS","display_name":"EXAMINATION OF THE EFFECTS OF VALPROIC ACID EXPOSURE OR P300 PROTEIN INHIBITION ON THE BALANCE OF APOPTOSIS AND PROLIFERATION IN P19 EMBRYONAL CARCINOMA CELLS","publication_year":2016,"publication_date":"2016-08-26","ids":{"openalex":"https://openalex.org/W2565726679","mag":"2565726679"},"language":"en","primary_location":{"id":"pmh:oai:queensu.scholaris.ca:1974/14754","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1974/14754","pdf_url":null,"source":{"id":"https://openalex.org/S4306402568","display_name":"QSpace (Queen's University Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I204722609","host_organization_name":"Queen's University","host_organization_lineage":["https://openalex.org/I204722609"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026535803","display_name":"Jordan Bricker","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jordan Bricker","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5026535803"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11736","display_name":"Histone Deacetylase Inhibitors Research","score":0.5601000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11736","display_name":"Histone Deacetylase Inhibitors Research","score":0.5601000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":0.10440000146627426,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.0697999969124794,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/valproic-acid","display_name":"valproic acid","score":0.9959999918937683},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.6110000014305115},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.996999979019165},{"id":"https://openalex.org/keywords/p19-cells","display_name":"P19 cells","score":0.8389999866485596},{"id":"https://openalex.org/keywords/embryonal-carcinoma-cells","display_name":"embryonal carcinoma cells","score":0.8989999890327454},{"id":"https://openalex.org/keywords/histone-deacetylase-inhibition","display_name":"histone deacetylase inhibition","score":0.8370000123977661}],"concepts":[{"id":"https://openalex.org/C2777172819","wikidata":"https://www.wikidata.org/wiki/Q240642","display_name":"Valproic Acid","level":3,"score":0.8215983510017395},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.7565938234329224},{"id":"https://openalex.org/C2780327976","wikidata":"https://www.wikidata.org/wiki/Q1451877","display_name":"Embryonal carcinoma","level":4,"score":0.5832780003547668},{"id":"https://openalex.org/C26805974","wikidata":"https://www.wikidata.org/wiki/Q7117837","display_name":"P19 cell","level":5,"score":0.5582216382026672},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.44304358959198},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4061744809150696},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.350403368473053},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.34207063913345337},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33973586559295654},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2562115788459778},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.23969349265098572},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.19586116075515747},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1359688639640808},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.12368032336235046},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09485477209091187},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.07828345894813538},{"id":"https://openalex.org/C20875687","wikidata":"https://www.wikidata.org/wiki/Q2642600","display_name":"Adult stem cell","level":4,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:queensu.scholaris.ca:1974/14754","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1974/14754","pdf_url":null,"source":{"id":"https://openalex.org/S4306402568","display_name":"QSpace (Queen's University Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I204722609","host_organization_name":"Queen's University","host_organization_lineage":["https://openalex.org/I204722609"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"thesis"},{"id":"mag:2565726679","doi":null,"is_oa":false,"landing_page_url":"https://qspace.library.queensu.ca/bitstream/1974/14754/1/Bricker_Jordan_K_201608_MSc.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9789000153541565}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W1565312988","https://openalex.org/W1576171467","https://openalex.org/W1884928119","https://openalex.org/W1969788568","https://openalex.org/W1975761225","https://openalex.org/W1978669073","https://openalex.org/W1991395601","https://openalex.org/W1992125440","https://openalex.org/W1993712190","https://openalex.org/W1994514343","https://openalex.org/W2006131488","https://openalex.org/W2007427704","https://openalex.org/W2008622536","https://openalex.org/W2013734499","https://openalex.org/W2023708410","https://openalex.org/W2025013855","https://openalex.org/W2027761377","https://openalex.org/W2027815400","https://openalex.org/W2032713647","https://openalex.org/W2043654167","https://openalex.org/W2044227662","https://openalex.org/W2044626217","https://openalex.org/W2047732548","https://openalex.org/W2062809474","https://openalex.org/W2069430143","https://openalex.org/W2071383476","https://openalex.org/W2072419481","https://openalex.org/W2072669480","https://openalex.org/W2075626786","https://openalex.org/W2080364290","https://openalex.org/W2084301200","https://openalex.org/W2090381051","https://openalex.org/W2091228398","https://openalex.org/W2094198005","https://openalex.org/W2099008736","https://openalex.org/W2100288005","https://openalex.org/W2105999198","https://openalex.org/W2106775330","https://openalex.org/W2107450703","https://openalex.org/W2112632935","https://openalex.org/W2113693564","https://openalex.org/W2117691193","https://openalex.org/W2121273360","https://openalex.org/W2122431006","https://openalex.org/W2123763356","https://openalex.org/W2125355900","https://openalex.org/W2132760127","https://openalex.org/W2134374915","https://openalex.org/W2134511627","https://openalex.org/W2150290220","https://openalex.org/W2154352037","https://openalex.org/W2155326660","https://openalex.org/W2161413382","https://openalex.org/W2186843249","https://openalex.org/W2265459094","https://openalex.org/W2313581099","https://openalex.org/W2343980063","https://openalex.org/W2345561050","https://openalex.org/W2378720171"],"related_works":["https://openalex.org/W7216956948","https://openalex.org/W2034545959","https://openalex.org/W7099210304","https://openalex.org/W7223289463","https://openalex.org/W2392942215","https://openalex.org/W3133494078","https://openalex.org/W6922510565","https://openalex.org/W1423960553","https://openalex.org/W2370354267","https://openalex.org/W7096429088"],"abstract_inverted_index":{"Thesis":[0],"(Master,":[1],"Pharmacology":[2],"&":[3],"Toxicology)":[4],"--":[5],"Queen's":[6],"University,":[7],"2016-08-25":[8],"22:29:17.202":[9]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-09-03T10:48:47.769340","created_date":"2017-01-06T00:00:00"}