{"id":"https://openalex.org/W2563064463","doi":null,"title":"Apolipoprotein E phenotypes and B-amyloid (1-40) levels in demented patients in Greece","display_name":"Apolipoprotein E phenotypes and B-amyloid (1-40) levels in demented patients in Greece","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W2563064463","mag":"2563064463"},"language":"en","primary_location":{"id":"mag:2563064463","doi":null,"is_oa":false,"landing_page_url":"https://ikee.lib.auth.gr/record/280942","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113708499","display_name":"Eleni Hatzifilippou","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u0395. Hatzifilippou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057716586","display_name":"T. Banaki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T. Banaki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025117856","display_name":"J. Baloyannis","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Baloyannis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080935494","display_name":"Effrosyni Koutsouraki","orcid":"https://orcid.org/0000-0001-6057-3749","observed_orcids":["https://orcid.org/0000-0001-6057-3749"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Effrosyni Koutsouraki","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6057-3749","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084523497","display_name":"Stavros Balogiannis","orcid":"https://orcid.org/0000-0002-6865-1075","observed_orcids":["https://orcid.org/0000-0002-6865-1075"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stavros Balogiannis","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6865-1075","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111392426","display_name":"Vasiliki Kosta","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vasiliki Kosta","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"83","last_page":"89"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.8065999746322632,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.8065999746322632,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.19189999997615814,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/apolipoprotein-e","display_name":"apolipoprotein E","score":0.9419999718666077},{"id":"https://openalex.org/keywords/amyloid-beta-40","display_name":"A\u03b240","score":0.8809999823570251},{"id":"https://openalex.org/keywords/plasma-amyloid-beta","display_name":"plasma amyloid-beta","score":0.7639999985694885},{"id":"https://openalex.org/keywords/dementia","display_name":"dementia","score":0.9620000123977661},{"id":"https://openalex.org/keywords/dementia-severity","display_name":"dementia severity","score":0.7760000228881836},{"id":"https://openalex.org/keywords/apoe-epsilon4","display_name":"APOE \u03b54","score":0.5590000152587891},{"id":"https://openalex.org/keywords/apoe3","display_name":"APOE3","score":0.824999988079071},{"id":"https://openalex.org/keywords/apoe2","display_name":"APOE2","score":0.7089999914169312},{"id":"https://openalex.org/keywords/genetic-risk-factors","display_name":"genetic risk factors","score":0.503000020980835}],"concepts":[{"id":"https://openalex.org/C57089818","wikidata":"https://www.wikidata.org/wiki/Q424728","display_name":"Apolipoprotein E","level":3,"score":0.792424738407135},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.7382452487945557},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.6933115720748901},{"id":"https://openalex.org/C2777633098","wikidata":"https://www.wikidata.org/wiki/Q2736051","display_name":"Amyloid (mycology)","level":2,"score":0.5989196300506592},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5986020565032959},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5289271473884583},{"id":"https://openalex.org/C2779951007","wikidata":"https://www.wikidata.org/wiki/Q816798","display_name":"Amyloidosis","level":2,"score":0.4781968593597412},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4569118916988373},{"id":"https://openalex.org/C62746215","wikidata":"https://www.wikidata.org/wiki/Q14890615","display_name":"Apolipoprotein B","level":3,"score":0.44962769746780396},{"id":"https://openalex.org/C3019216857","wikidata":"https://www.wikidata.org/wiki/Q417667","display_name":"\u03b2 amyloid","level":4,"score":0.42724621295928955},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.3575640320777893},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.35090261697769165},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.31546759605407715},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2850364148616791},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19976845383644104},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.19331926107406616},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.17636454105377197},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1186898946762085}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2563064463","doi":null,"is_oa":false,"landing_page_url":"https://ikee.lib.auth.gr/record/280942","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1976358248","https://openalex.org/W1993948405","https://openalex.org/W2003143015","https://openalex.org/W2006409771","https://openalex.org/W2035589234","https://openalex.org/W2080341716","https://openalex.org/W2131975162","https://openalex.org/W2137903730","https://openalex.org/W2150790063"],"related_works":["https://openalex.org/W2138877132","https://openalex.org/W2347255212","https://openalex.org/W2341558723","https://openalex.org/W2017779103","https://openalex.org/W2110450363","https://openalex.org/W2222668575","https://openalex.org/W1984093145","https://openalex.org/W1971687966","https://openalex.org/W3217619031","https://openalex.org/W4312087150"],"abstract_inverted_index":{"The":[0],"aim":[1],"of":[2,17,25,32,48,54,74,90,118],"our":[3],"investigation":[4],"was":[5],"to":[6],"correlate":[7],"the":[8,12,15,23,30,67,71,84,106,115],"ApoE":[9,107],"phenotypes":[10,108],"with":[11,22,66,83,105],"type":[13],"and":[14,60],"severity":[16],"dementia":[18],"as":[19,21,97,110,112],"well":[20,111],"levels":[24,89,117],"amyloid":[26,76,91,119],"\u03b2":[27,77,92],"(1-40)":[28,78,93],"in":[29],"plasma":[31,75],"demented":[33],"patients.":[34],"We":[35],"have":[36],"examined":[37],"40":[38],"patients":[39,104],"(27":[40],"females,":[41],"13":[42],"males),":[43],"suffered":[44],"from":[45],"several":[46],"types":[47],"dementia,":[49],"at":[50],"a":[51],"mean":[52],"age":[53],"70.4\u00b110.1":[55],"years":[56,62],"old":[57],"for":[58,63],"females":[59],"69.4\u00b110.5":[61],"males.":[64],"Patients":[65,82],"phenotype":[68],"E3/2":[69,113],"demonstrated":[70,114],"highest":[72,116],"concentrations":[73],"(mean":[79,94],"321.8":[80],"pg/ml).":[81],"E4/3":[85,109],"isoform":[86],"revealed":[87],"high":[88],"210.6":[95],"pg/ml)":[96],"well.":[98],"Our":[99],"present":[100],"results":[101],"indicate":[102],"that":[103],"\u00e2":[120],"(1-40).":[121]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-01-06T00:00:00"}