{"id":"https://openalex.org/W2561417170","doi":null,"title":"Characterizing the Role of Nanoparticle Design on Tumor Transport and Stability in the Extracellular Environment","display_name":"Characterizing the Role of Nanoparticle Design on Tumor Transport and Stability in the Extracellular Environment","publication_year":2014,"publication_date":"2014-06-01","ids":{"openalex":"https://openalex.org/W2561417170","mag":"2561417170"},"language":"en","primary_location":{"id":"pmh:oai:utoronto.scholaris.ca:1807/68359","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/68359","pdf_url":"https://utoronto.scholaris.ca/bitstreams/07700045-85b6-4f1a-a1a9-dc66ce8bfbac/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://utoronto.scholaris.ca/bitstreams/07700045-85b6-4f1a-a1a9-dc66ce8bfbac/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047253093","display_name":"Alexandre Albanese","orcid":"https://orcid.org/0000-0001-7093-574X","observed_orcids":["https://orcid.org/0000-0001-7093-574X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Alexandre Albanese","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5047253093"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11686","display_name":"Dendrimers and Hyperbranched Polymers","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nanoparticle-design","display_name":"nanoparticle design","score":0.9330000281333923},{"id":"https://openalex.org/keywords/tumor-targeting","display_name":"tumor targeting","score":0.7630000114440918},{"id":"https://openalex.org/keywords/extracellular-environment","display_name":"extracellular environment","score":0.7649999856948853},{"id":"https://openalex.org/keywords/nanoparticle-stability","display_name":"nanoparticle stability","score":0.9760000109672546},{"id":"https://openalex.org/keywords/nanomedicine","display_name":"nanomedicine","score":0.7329999804496765},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"drug delivery","score":0.5540000200271606},{"id":"https://openalex.org/keywords/nanomaterial-synthesis","display_name":"nanomaterial synthesis","score":0.7540000081062317}],"concepts":[{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.6370100378990173},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.6180994510650635},{"id":"https://openalex.org/C112972136","wikidata":"https://www.wikidata.org/wiki/Q7595718","display_name":"Stability (learning theory)","level":2,"score":0.4981400966644287},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4590974450111389},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3462083339691162},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.3444809317588806},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3200782537460327},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.30820995569229126},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20479395985603333},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:utoronto.scholaris.ca:1807/68359","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/68359","pdf_url":"https://utoronto.scholaris.ca/bitstreams/07700045-85b6-4f1a-a1a9-dc66ce8bfbac/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"mag:2561417170","doi":null,"is_oa":false,"landing_page_url":"https://tspace.library.utoronto.ca/bitstream/1807/68359/1/Albanese_Alexandre_201406_PhD_thesis.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:utoronto.scholaris.ca:1807/68359","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/68359","pdf_url":"https://utoronto.scholaris.ca/bitstreams/07700045-85b6-4f1a-a1a9-dc66ce8bfbac/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2561417170.pdf","grobid_xml":"https://content.openalex.org/works/W2561417170.grobid-xml"},"referenced_works_count":291,"referenced_works":["https://openalex.org/W111438725","https://openalex.org/W178698445","https://openalex.org/W239348210","https://openalex.org/W257050988","https://openalex.org/W286579105","https://openalex.org/W562467826","https://openalex.org/W617436691","https://openalex.org/W647381190","https://openalex.org/W1493048246","https://openalex.org/W1498713448","https://openalex.org/W1511436383","https://openalex.org/W1586420148","https://openalex.org/W1636022800","https://openalex.org/W1672766972","https://openalex.org/W1871308790","https://openalex.org/W1906279522","https://openalex.org/W1956944003","https://openalex.org/W1963565300","https://openalex.org/W1963745089","https://openalex.org/W1964067749","https://openalex.org/W1965097716","https://openalex.org/W1965232052","https://openalex.org/W1965709929","https://openalex.org/W1966239026","https://openalex.org/W1967217835","https://openalex.org/W1967221930","https://openalex.org/W1967850823","https://openalex.org/W1968492694","https://openalex.org/W1968583232","https://openalex.org/W1969471545","https://openalex.org/W1969540651","https://openalex.org/W1969645755","https://openalex.org/W1969814828","https://openalex.org/W1970238879","https://openalex.org/W1970727831","https://openalex.org/W1971942263","https://openalex.org/W1972257652","https://openalex.org/W1973831032","https://openalex.org/W1975754293","https://openalex.org/W1976301815","https://openalex.org/W1978002868","https://openalex.org/W1979232921","https://openalex.org/W1979639615","https://openalex.org/W1979721854","https://openalex.org/W1980742772","https://openalex.org/W1984649408","https://openalex.org/W1984804948","https://openalex.org/W1985006200","https://openalex.org/W1985744874","https://openalex.org/W1985858988","https://openalex.org/W1985997303","https://openalex.org/W1986076794","https://openalex.org/W1987521215","https://openalex.org/W1988190543","https://openalex.org/W1988217845","https://openalex.org/W1988505580","https://openalex.org/W1989025666","https://openalex.org/W1989266670","https://openalex.org/W1989642666","https://openalex.org/W1990791836","https://openalex.org/W1990796256","https://openalex.org/W1993390114","https://openalex.org/W1993418575","https://openalex.org/W1994333466","https://openalex.org/W1995340305","https://openalex.org/W1995599967","https://openalex.org/W1995704440","https://openalex.org/W1996139192","https://openalex.org/W1996993122","https://openalex.org/W1997153101","https://openalex.org/W1997203755","https://openalex.org/W1999562731","https://openalex.org/W2000076998","https://openalex.org/W2000482482","https://openalex.org/W2001809903","https://openalex.org/W2002391544","https://openalex.org/W2002661845","https://openalex.org/W2002870035","https://openalex.org/W2003336829","https://openalex.org/W2003451349","https://openalex.org/W2003558371","https://openalex.org/W2003741425","https://openalex.org/W2004197988","https://openalex.org/W2004761363","https://openalex.org/W2005585148","https://openalex.org/W2005840555","https://openalex.org/W2006165138","https://openalex.org/W2007256551","https://openalex.org/W2007573145","https://openalex.org/W2007988714","https://openalex.org/W2008800413","https://openalex.org/W2009583928","https://openalex.org/W2009805582","https://openalex.org/W2009963235","https://openalex.org/W2010225410","https://openalex.org/W2010477422","https://openalex.org/W2011032800","https://openalex.org/W2012607179","https://openalex.org/W2012867417","https://openalex.org/W2013722826","https://openalex.org/W2015869127","https://openalex.org/W2016927087","https://openalex.org/W2018435413","https://openalex.org/W2018478612","https://openalex.org/W2019555018","https://openalex.org/W2021234842","https://openalex.org/W2022590560","https://openalex.org/W2023453467","https://openalex.org/W2023640794","https://openalex.org/W2024360896","https://openalex.org/W2025036947","https://openalex.org/W2025188006","https://openalex.org/W2025868400","https://openalex.org/W2026323174","https://openalex.org/W2027239458","https://openalex.org/W2028156849","https://openalex.org/W2028837111","https://openalex.org/W2030635479","https://openalex.org/W2031938923","https://openalex.org/W2033715508","https://openalex.org/W2034618316","https://openalex.org/W2035697316","https://openalex.org/W2035901751","https://openalex.org/W2036279456","https://openalex.org/W2037827070","https://openalex.org/W2038246612","https://openalex.org/W2038324181","https://openalex.org/W2041771455","https://openalex.org/W2042452418","https://openalex.org/W2042949277","https://openalex.org/W2044054332","https://openalex.org/W2044794349","https://openalex.org/W2045459881","https://openalex.org/W2045537130","https://openalex.org/W2045811489","https://openalex.org/W2046851174","https://openalex.org/W2047348515","https://openalex.org/W2047417642","https://openalex.org/W2048262430","https://openalex.org/W2048926712","https://openalex.org/W2048939436","https://openalex.org/W2049092063","https://openalex.org/W2049565903","https://openalex.org/W2050886209","https://openalex.org/W2050910055","https://openalex.org/W2052566608","https://openalex.org/W2054283902","https://openalex.org/W2054311522","https://openalex.org/W2054537734","https://openalex.org/W2055142978","https://openalex.org/W2055829654","https://openalex.org/W2056262153","https://openalex.org/W2057910069","https://openalex.org/W2059132797","https://openalex.org/W2059978839","https://openalex.org/W2061135343","https://openalex.org/W2061999521","https://openalex.org/W2062430935","https://openalex.org/W2064093384","https://openalex.org/W2064615886","https://openalex.org/W2065426711","https://openalex.org/W2066351250","https://openalex.org/W2067796149","https://openalex.org/W2069693261","https://openalex.org/W2069873753","https://openalex.org/W2069928673","https://openalex.org/W2070003597","https://openalex.org/W2070185859","https://openalex.org/W2071020745","https://openalex.org/W2071636590","https://openalex.org/W2071659125","https://openalex.org/W2072236397","https://openalex.org/W2072247105","https://openalex.org/W2072931590","https://openalex.org/W2076025083","https://openalex.org/W2076663232","https://openalex.org/W2076759023","https://openalex.org/W2077021162","https://openalex.org/W2077228161","https://openalex.org/W2077841486","https://openalex.org/W2078816993","https://openalex.org/W2080076901","https://openalex.org/W2081424254","https://openalex.org/W2082041852","https://openalex.org/W2082078647","https://openalex.org/W2082511916","https://openalex.org/W2083710155","https://openalex.org/W2084186494","https://openalex.org/W2084405056","https://openalex.org/W2086439640","https://openalex.org/W2086451443","https://openalex.org/W2087852222","https://openalex.org/W2088170069","https://openalex.org/W2088223764","https://openalex.org/W2089391836","https://openalex.org/W2092045871","https://openalex.org/W2092492380","https://openalex.org/W2093279818","https://openalex.org/W2094437628","https://openalex.org/W2094842452","https://openalex.org/W2096406493","https://openalex.org/W2097095007","https://openalex.org/W2099747712","https://openalex.org/W2100627342","https://openalex.org/W2101312385","https://openalex.org/W2102247052","https://openalex.org/W2106878780","https://openalex.org/W2107682048","https://openalex.org/W2108611432","https://openalex.org/W2108615682","https://openalex.org/W2108623236","https://openalex.org/W2109827510","https://openalex.org/W2110012055","https://openalex.org/W2110634891","https://openalex.org/W2110636972","https://openalex.org/W2112001302","https://openalex.org/W2112165279","https://openalex.org/W2112280691","https://openalex.org/W2113972541","https://openalex.org/W2116263694","https://openalex.org/W2116813457","https://openalex.org/W2117630026","https://openalex.org/W2118167053","https://openalex.org/W2119378732","https://openalex.org/W2120277821","https://openalex.org/W2122751535","https://openalex.org/W2123310574","https://openalex.org/W2125123295","https://openalex.org/W2125442511","https://openalex.org/W2126163864","https://openalex.org/W2128797730","https://openalex.org/W2129191745","https://openalex.org/W2129209927","https://openalex.org/W2130052270","https://openalex.org/W2131580401","https://openalex.org/W2132651708","https://openalex.org/W2133112122","https://openalex.org/W2133391229","https://openalex.org/W2134891510","https://openalex.org/W2135658169","https://openalex.org/W2137358137","https://openalex.org/W2137864764","https://openalex.org/W2138460593","https://openalex.org/W2138874065","https://openalex.org/W2139344679","https://openalex.org/W2141518860","https://openalex.org/W2143534453","https://openalex.org/W2144780390","https://openalex.org/W2145364955","https://openalex.org/W2147449180","https://openalex.org/W2148924929","https://openalex.org/W2150146274","https://openalex.org/W2152366705","https://openalex.org/W2152877944","https://openalex.org/W2153130388","https://openalex.org/W2155118487","https://openalex.org/W2156969927","https://openalex.org/W2157016784","https://openalex.org/W2157571064","https://openalex.org/W2158138220","https://openalex.org/W2158180922","https://openalex.org/W2158558808","https://openalex.org/W2159147379","https://openalex.org/W2159946927","https://openalex.org/W2160045751","https://openalex.org/W2160312052","https://openalex.org/W2161279046","https://openalex.org/W2161946327","https://openalex.org/W2163308073","https://openalex.org/W2164845223","https://openalex.org/W2166828161","https://openalex.org/W2167798860","https://openalex.org/W2168090230","https://openalex.org/W2168321305","https://openalex.org/W2168909179","https://openalex.org/W2169081435","https://openalex.org/W2169207702","https://openalex.org/W2169515956","https://openalex.org/W2169659582","https://openalex.org/W2170829363","https://openalex.org/W2171083652","https://openalex.org/W2171864173","https://openalex.org/W2220693209","https://openalex.org/W2283256024","https://openalex.org/W2312662255","https://openalex.org/W2322463543","https://openalex.org/W2324813121","https://openalex.org/W2326063830","https://openalex.org/W2334645916","https://openalex.org/W2770540844","https://openalex.org/W2912349604"],"related_works":["https://openalex.org/W1985968515","https://openalex.org/W2581403421","https://openalex.org/W2326063830","https://openalex.org/W2015868317","https://openalex.org/W2595933318","https://openalex.org/W6988643748","https://openalex.org/W7110499847","https://openalex.org/W2102866212","https://openalex.org/W4250156341","https://openalex.org/W2124130800"],"abstract_inverted_index":{"Nanotechnology":[0],"has":[1],"emerged":[2],"as":[3],"an":[4,24],"exciting":[5],"strategy":[6],"for":[7,43],"the":[8],"delivery":[9],"of":[10,27],"diagnostic":[11],"and":[12],"therapeutic":[13],"agents":[14],"into":[15],"established":[16],"tumors.":[17],"Advancements":[18],"in":[19],"nanomaterial":[20],"synthesis":[21],"have":[22],"generated":[23],"extensive":[25],"number":[26],"nanoparticle":[28],"designs":[29],"made":[30],"from":[31],"different":[32],"materials.":[33],"Unfortunately,":[34],"it":[35],"remains":[36],"impossible":[37],"to":[38],"predict":[39],"a":[40],"design's":[41],"effectiveness":[42]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2017-01-06T00:00:00"}
