{"id":"https://openalex.org/W2561266809","doi":"https://doi.org/10.12688/f1000research.10509.1","title":"Inducible targeting of CNS astrocytes in Aldh1l1-CreERT2 BAC transgenic mice","display_name":"Inducible targeting of CNS astrocytes in Aldh1l1-CreERT2 BAC transgenic mice","publication_year":2016,"publication_date":"2016-12-30","ids":{"openalex":"https://openalex.org/W2561266809","doi":"https://doi.org/10.12688/f1000research.10509.1","mag":"2561266809","pmid":"https://pubmed.ncbi.nlm.nih.gov/28149504","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5265728"},"language":"en","primary_location":{"id":"doi:10.12688/f1000research.10509.1","doi":"https://doi.org/10.12688/f1000research.10509.1","is_oa":true,"landing_page_url":"https://doi.org/10.12688/f1000research.10509.1","pdf_url":"https://f1000research.com/articles/5-2934/v1/pdf","source":{"id":"https://openalex.org/S4210239046","display_name":"F1000Research","issn_l":"2046-1402","issn":["2046-1402"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320357","host_organization_name":"Faculty of 1000","host_organization_lineage":["https://openalex.org/P4310320357","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Faculty of 1000","Taylor & Francis"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"F1000Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://f1000research.com/articles/5-2934/v1/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066404563","display_name":"Jan Winchenbach","orcid":"https://orcid.org/0009-0000-9157-7806","observed_orcids":["https://orcid.org/0009-0000-9157-7806"]},"institutions":[{"id":"https://openalex.org/I4210137682","display_name":"Max Planck Institute of Experimental Medicine","ror":"https://ror.org/04a7f6w43","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210137682","https://openalex.org/I4387154714"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jan Winchenbach","raw_affiliation_strings":["Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen, Germany","Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I4210137682"]},{"raw_affiliation_string":"Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen","institution_ids":["https://openalex.org/I4210137682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065154925","display_name":"Tim D\u00fcking","orcid":"https://orcid.org/0000-0002-4347-7648","observed_orcids":["https://orcid.org/0000-0002-4347-7648"]},"institutions":[{"id":"https://openalex.org/I4210137682","display_name":"Max Planck Institute of Experimental Medicine","ror":"https://ror.org/04a7f6w43","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210137682","https://openalex.org/I4387154714"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Tim D\u00fcking","raw_affiliation_strings":["Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen, Germany","Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen"],"raw_orcid":"https://orcid.org/0000-0002-4347-7648","affiliations":[{"raw_affiliation_string":"Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I4210137682"]},{"raw_affiliation_string":"Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen","institution_ids":["https://openalex.org/I4210137682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064438209","display_name":"Stefan A. Berghoff","orcid":"https://orcid.org/0000-0002-3794-7295","observed_orcids":["https://orcid.org/0000-0002-3794-7295"]},"institutions":[{"id":"https://openalex.org/I4210137682","display_name":"Max Planck Institute of Experimental Medicine","ror":"https://ror.org/04a7f6w43","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210137682","https://openalex.org/I4387154714"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefan A. Berghoff","raw_affiliation_strings":["Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen, Germany","Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I4210137682"]},{"raw_affiliation_string":"Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen","institution_ids":["https://openalex.org/I4210137682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091177645","display_name":"Sina K. Stumpf","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137682","display_name":"Max Planck Institute of Experimental Medicine","ror":"https://ror.org/04a7f6w43","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210137682","https://openalex.org/I4387154714"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sina K. Stumpf","raw_affiliation_strings":["Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen, Germany","Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I4210137682"]},{"raw_affiliation_string":"Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen","institution_ids":["https://openalex.org/I4210137682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020599553","display_name":"Swen H\u00fclsmann","orcid":"https://orcid.org/0000-0001-5042-8724","observed_orcids":["https://orcid.org/0000-0001-5042-8724"]},"institutions":[{"id":"https://openalex.org/I4210116730","display_name":"Universit\u00e4tsmedizin G\u00f6ttingen","ror":"https://ror.org/021ft0n22","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210116730"]},{"id":"https://openalex.org/I4210129011","display_name":"Nanoscale Microscopy and Molecular Physiology of the Brain Cluster of Excellence 171 \u2014 DFG Research Center 103","ror":"https://ror.org/02wkzzr31","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129011"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Swen H\u00fclsmann","raw_affiliation_strings":["Clinic for Anesthesiology, Research Group Central Respiratory Control, University Medical Center G\u00f6ttingen, Experimental Neuroanesthesiology, G\u00f6ttingen, Germany; Center Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), G\u00f6ttingen, Germany","Center Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), G\u00f6ttingen","Clinic for Anesthesiology, Research Group Central Respiratory Control, University Medical Center G\u00f6ttingen, Experimental Neuroanesthesiology, G\u00f6ttingen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinic for Anesthesiology, Research Group Central Respiratory Control, University Medical Center G\u00f6ttingen, Experimental Neuroanesthesiology, G\u00f6ttingen, Germany; Center Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I4210116730","https://openalex.org/I4210129011"]},{"raw_affiliation_string":"Center Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), G\u00f6ttingen","institution_ids":["https://openalex.org/I4210129011"]},{"raw_affiliation_string":"Clinic for Anesthesiology, Research Group Central Respiratory Control, University Medical Center G\u00f6ttingen, Experimental Neuroanesthesiology, G\u00f6ttingen","institution_ids":["https://openalex.org/I4210116730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038465445","display_name":"Klaus\u2010Armin Nave","orcid":"https://orcid.org/0000-0001-8724-9666","observed_orcids":["https://orcid.org/0000-0001-8724-9666"]},"institutions":[{"id":"https://openalex.org/I4210129011","display_name":"Nanoscale Microscopy and Molecular Physiology of the Brain Cluster of Excellence 171 \u2014 DFG Research Center 103","ror":"https://ror.org/02wkzzr31","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129011"]},{"id":"https://openalex.org/I4210137682","display_name":"Max Planck Institute of Experimental Medicine","ror":"https://ror.org/04a7f6w43","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210137682","https://openalex.org/I4387154714"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Klaus-Armin Nave","raw_affiliation_strings":["Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen, Germany; Center Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), G\u00f6ttingen, Germany","Center Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), G\u00f6ttingen","Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen"],"raw_orcid":"https://orcid.org/0000-0001-8724-9666","affiliations":[{"raw_affiliation_string":"Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen, Germany; Center Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I4210129011","https://openalex.org/I4210137682"]},{"raw_affiliation_string":"Center Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), G\u00f6ttingen","institution_ids":["https://openalex.org/I4210129011"]},{"raw_affiliation_string":"Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen","institution_ids":["https://openalex.org/I4210137682"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072237751","display_name":"Gesine Saher","orcid":"https://orcid.org/0000-0003-3507-9604","observed_orcids":["https://orcid.org/0000-0003-3507-9604"]},"institutions":[{"id":"https://openalex.org/I4210137682","display_name":"Max Planck Institute of Experimental Medicine","ror":"https://ror.org/04a7f6w43","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210137682","https://openalex.org/I4387154714"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Gesine Saher","raw_affiliation_strings":["Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen, Germany","Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen"],"raw_orcid":"https://orcid.org/0000-0003-3507-9604","affiliations":[{"raw_affiliation_string":"Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I4210137682"]},{"raw_affiliation_string":"Department of Neurogenetics, Max Planck Institute of Experimental Medicine, G\u00f6ttingen","institution_ids":["https://openalex.org/I4210137682"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5038465445","https://openalex.org/A5072237751"],"corresponding_institution_ids":["https://openalex.org/I4210129011","https://openalex.org/I4210137682"],"apc_list":{"value":1350,"currency":"USD","value_usd":1350},"apc_paid":{"value":1350,"currency":"USD","value_usd":1350},"fwci":1.2209,"has_fulltext":true,"cited_by_count":74,"citation_normalized_percentile":{"value":0.76269817,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"5","issue":null,"first_page":"2934","last_page":"2934"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.6942999958992004,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.6942999958992004,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.1696999967098236,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.039400000125169754,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/astrocytes","display_name":"astrocytes","score":0.9100000262260437},{"id":"https://openalex.org/keywords/creert2","display_name":"CreERT2","score":0.6759999990463257},{"id":"https://openalex.org/keywords/inducible-cre-recombinase","display_name":"inducible Cre recombinase","score":0.8169999718666077},{"id":"https://openalex.org/keywords/bac-transgenic-mice","display_name":"BAC transgenic mice","score":0.9549999833106995},{"id":"https://openalex.org/keywords/neuronal-glial-interactions","display_name":"neuron-glia interactions","score":0.8309999704360962},{"id":"https://openalex.org/keywords/neocortex","display_name":"neocortex","score":0.8019999861717224},{"id":"https://openalex.org/keywords/neurovascular-coupling","display_name":"neurovascular coupling","score":0.7020000219345093},{"id":"https://openalex.org/keywords/cerebral-metabolism","display_name":"brain metabolism","score":0.9409999847412109},{"id":"https://openalex.org/keywords/synaptic-plasticity","display_name":"synaptic plasticity","score":0.8500000238418579}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7428444027900696},{"id":"https://openalex.org/C125929170","wikidata":"https://www.wikidata.org/wiki/Q908966","display_name":"Cre recombinase","level":5,"score":0.6531513333320618},{"id":"https://openalex.org/C2777222312","wikidata":"https://www.wikidata.org/wiki/Q726562","display_name":"Neocortex","level":2,"score":0.5933103561401367},{"id":"https://openalex.org/C102230213","wikidata":"https://www.wikidata.org/wiki/Q430117","display_name":"Transgene","level":3,"score":0.5474728345870972},{"id":"https://openalex.org/C2779830541","wikidata":"https://www.wikidata.org/wiki/Q1622829","display_name":"Microglia","level":3,"score":0.4157232642173767},{"id":"https://openalex.org/C141035611","wikidata":"https://www.wikidata.org/wiki/Q5532934","display_name":"Genetically modified mouse","level":4,"score":0.40747547149658203},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2976371943950653},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22923412919044495},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.21519899368286133},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.12173956632614136},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.09993436932563782}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.12688/f1000research.10509.1","doi":"https://doi.org/10.12688/f1000research.10509.1","is_oa":true,"landing_page_url":"https://doi.org/10.12688/f1000research.10509.1","pdf_url":"https://f1000research.com/articles/5-2934/v1/pdf","source":{"id":"https://openalex.org/S4210239046","display_name":"F1000Research","issn_l":"2046-1402","issn":["2046-1402"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320357","host_organization_name":"Faculty of 1000","host_organization_lineage":["https://openalex.org/P4310320357","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Faculty of 1000","Taylor & Francis"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"F1000Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4155860","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5265728","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5265728","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5265728","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"F1000Res","raw_type":"Text"},{"id":"pmid:28149504","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28149504","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"F1000Research","raw_type":"Journal Article"},{"id":"pmh:oai:pure.mpg.de:item_2390024","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11858/00-001M-0000-002C-5B56-B","pdf_url":"http://hdl.handle.net/11858/00-001M-0000-002C-5B56-B","source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Faculty of 1000 Research","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:53c8f73488c14ec299224e06b6b62fe4","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/53c8f73488c14ec299224e06b6b62fe4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"F1000Research, Vol 5 (2016)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.12688/f1000research.10509.1","doi":"https://doi.org/10.12688/f1000research.10509.1","is_oa":true,"landing_page_url":"https://doi.org/10.12688/f1000research.10509.1","pdf_url":"https://f1000research.com/articles/5-2934/v1/pdf","source":{"id":"https://openalex.org/S4210239046","display_name":"F1000Research","issn_l":"2046-1402","issn":["2046-1402"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320357","host_organization_name":"Faculty of 1000","host_organization_lineage":["https://openalex.org/P4310320357","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Faculty of 1000","Taylor & Francis"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"F1000Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2320301096","display_name":null,"funder_award_id":"SA 2014/2-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G2927478161","display_name":null,"funder_award_id":"SFB/TR43,  SPP1757 SA 2014/2-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G3650154318","display_name":null,"funder_award_id":"SPP1757 SA 2014/2-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G509498957","display_name":null,"funder_award_id":"SPP-1757","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G731236078","display_name":null,"funder_award_id":"SFBTR43","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2561266809.pdf","grobid_xml":"https://content.openalex.org/works/W2561266809.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1549778670","https://openalex.org/W1981627824","https://openalex.org/W1985436254","https://openalex.org/W1986195427","https://openalex.org/W2005926878","https://openalex.org/W2008045627","https://openalex.org/W2008205503","https://openalex.org/W2033481352","https://openalex.org/W2035631224","https://openalex.org/W2038253875","https://openalex.org/W2048086625","https://openalex.org/W2054226892","https://openalex.org/W2054275187","https://openalex.org/W2059803506","https://openalex.org/W2084772990","https://openalex.org/W2104135721","https://openalex.org/W2109627278","https://openalex.org/W2124940469","https://openalex.org/W2131414694","https://openalex.org/W2146152985","https://openalex.org/W2147223211","https://openalex.org/W2155433808","https://openalex.org/W2238394920","https://openalex.org/W2559768163","https://openalex.org/W4416598126"],"related_works":["https://openalex.org/W7029276737","https://openalex.org/W2996475264","https://openalex.org/W2559768163","https://openalex.org/W1985436254","https://openalex.org/W2038253875","https://openalex.org/W2035631224","https://openalex.org/W4416973094","https://openalex.org/W4413907413","https://openalex.org/W7100342716","https://openalex.org/W2054226892"],"abstract_inverted_index":{"Background:":[0],"Studying":[1],"astrocytes":[2,102],"in":[3,37,63,71,83,103],"higher":[4],"brain":[5,106],"functions":[6],"has":[7],"been":[8],"hampered":[9],"by":[10],"the":[11,17,25,28,45],"lack":[12],"of":[13,20,44,113],"genetic":[14],"tools":[15],"for":[16,100],"efficient":[18,60],"expression":[19,80],"inducible":[21],"Cre":[22,53],"recombinase":[23],"throughout":[24],"CNS,":[26],"including":[27,87],"neocortex.":[29],"Methods:":[30],"Therefore,":[31],"we":[32],"generated":[33],"BAC":[34],"transgenic":[35],"mice,":[36,55],"which":[38],"CreERT2":[39],"is":[40],"expressed":[41],"under":[42],"control":[43],"Aldh1l1":[46],"regulatory":[47],"region.":[48],"Results:":[49],"When":[50],"crossbred":[51],"to":[52],"reporter":[54],"adult":[56],"Aldh1l1-CreERT2":[57,79,94],"mice":[58,95],"show":[59],"gene":[61],"targeting":[62],"astrocytes.":[64],"No":[65],"such":[66],"Cre-mediated":[67],"recombination":[68],"was":[69,81],"detectable":[70],"CNS":[72],"neurons,":[73],"oligodendrocytes,":[74],"and":[75,89,110],"microglia.":[76],"As":[77],"expected,":[78],"evident":[82],"several":[84],"peripheral":[85],"organs,":[86],"liver":[88],"kidney.":[90],"Conclusions:":[91],"Taken":[92],"together,":[93],"are":[96],"a":[97],"useful":[98],"tool":[99],"studying":[101],"neurovascular":[104],"coupling,":[105],"metabolism,":[107],"synaptic":[108],"plasticity":[109],"other":[111],"aspects":[112],"neuron-glia":[114],"interactions.":[115]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":16},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":18},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2017-01-06T00:00:00"}
